EP0643723A4 - HALOGENATION USING A HALO-VILSMEIER REAGENT. - Google Patents

HALOGENATION USING A HALO-VILSMEIER REAGENT.

Info

Publication number
EP0643723A4
EP0643723A4 EP93902957A EP93902957A EP0643723A4 EP 0643723 A4 EP0643723 A4 EP 0643723A4 EP 93902957 A EP93902957 A EP 93902957A EP 93902957 A EP93902957 A EP 93902957A EP 0643723 A4 EP0643723 A4 EP 0643723A4
Authority
EP
European Patent Office
Prior art keywords
halogenation
halo
vilsmeier reagent
vilsmeier
reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP93902957A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0643723A1 (en
Inventor
Neil Howard Baine
Donald Nathaniel Kline
Richard Eric Mewshaw
Franklin Owings
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0643723A1 publication Critical patent/EP0643723A1/en
Publication of EP0643723A4 publication Critical patent/EP0643723A4/en
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J3/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0066Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EP93902957A 1992-01-06 1993-01-06 HALOGENATION USING A HALO-VILSMEIER REAGENT. Ceased EP0643723A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US817179 1979-01-31
US81717992A 1992-01-06 1992-01-06
US94134892A 1992-09-04 1992-09-04
PCT/US1993/000079 WO1993014106A1 (en) 1992-01-06 1993-01-06 Halogenation using halo-vilsmeier reagent
US941348 2001-08-28

Publications (2)

Publication Number Publication Date
EP0643723A1 EP0643723A1 (en) 1995-03-22
EP0643723A4 true EP0643723A4 (en) 1995-05-10

Family

ID=27124147

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93902957A Ceased EP0643723A4 (en) 1992-01-06 1993-01-06 HALOGENATION USING A HALO-VILSMEIER REAGENT.

Country Status (23)

Country Link
EP (1) EP0643723A4 (zh)
JP (1) JPH07505138A (zh)
KR (1) KR940703849A (zh)
CN (1) CN1077201A (zh)
AP (1) AP370A (zh)
AU (1) AU666167B2 (zh)
BG (1) BG98887A (zh)
BR (1) BR9305786A (zh)
CA (1) CA2127272A1 (zh)
CZ (1) CZ161994A3 (zh)
FI (1) FI943214A0 (zh)
HU (1) HUT68273A (zh)
IL (1) IL104302A (zh)
MA (1) MA22761A1 (zh)
MX (1) MX9300025A (zh)
NO (1) NO942535L (zh)
NZ (1) NZ246788A (zh)
OA (1) OA09961A (zh)
RU (1) RU94038223A (zh)
SI (1) SI9300006A (zh)
SK (1) SK80094A3 (zh)
TW (1) TW300226B (zh)
WO (1) WO1993014106A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683995A (en) * 1992-11-18 1997-11-04 Smithkline Beecham Corporation 17 substituted acyl-3-carboxy 3,5-diene steroidals as α-reductase inhibitors
US5641765A (en) * 1992-11-18 1997-06-24 Smithkline Beecham Corporation 17-αand 17-βsubstituted acyl-3-carboxy-3,5-dienes and use in inhibiting 5-α-reductase
EP1765804A4 (en) 2004-06-08 2009-11-11 Univ Temple HETEROARYLSULFONES AND SULFONAMIDES AND THEIR THERAPEUTIC USES

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA883034B (en) * 1987-04-29 1989-03-29 Smithkline Beckman Corp Steroid 5-alpha-reductase inhibitors

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *

Also Published As

Publication number Publication date
EP0643723A1 (en) 1995-03-22
HUT68273A (en) 1995-06-28
CN1077201A (zh) 1993-10-13
NZ246788A (en) 1996-11-26
HU9402030D0 (en) 1994-09-28
CZ161994A3 (en) 1995-03-15
AU666167B2 (en) 1996-02-01
OA09961A (en) 1995-12-11
NO942535D0 (no) 1994-07-05
MX9300025A (es) 1994-01-31
AU3434893A (en) 1993-08-03
NO942535L (no) 1994-07-05
MA22761A1 (fr) 1993-10-01
TW300226B (zh) 1997-03-11
JPH07505138A (ja) 1995-06-08
CA2127272A1 (en) 1993-07-22
WO1993014106A1 (en) 1993-07-22
IL104302A (en) 1998-02-22
RU94038223A (ru) 1997-04-20
SI9300006A (en) 1993-09-30
KR940703849A (ko) 1994-12-12
IL104302A0 (en) 1993-05-13
FI943214A (fi) 1994-07-05
AP9300473A0 (en) 1993-01-31
SK80094A3 (en) 1994-12-07
FI943214A0 (fi) 1994-07-05
AP370A (en) 1994-11-10
BG98887A (bg) 1995-05-31
BR9305786A (pt) 1997-02-18

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