CY2507B1 - Novel fungal protease - Google Patents
Novel fungal proteaseInfo
- Publication number
- CY2507B1 CY2507B1 CY0500015A CY0500015A CY2507B1 CY 2507 B1 CY2507 B1 CY 2507B1 CY 0500015 A CY0500015 A CY 0500015A CY 0500015 A CY0500015 A CY 0500015A CY 2507 B1 CY2507 B1 CY 2507B1
- Authority
- CY
- Cyprus
- Prior art keywords
- subtilisin
- serine protease
- aspergillus
- type
- novel
- Prior art date
Links
- 108091005804 Peptidases Proteins 0.000 title 1
- 239000004365 Protease Substances 0.000 title 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 title 1
- 230000002538 fungal effect Effects 0.000 title 1
- 241000228212 Aspergillus Species 0.000 abstract 3
- 102000012479 Serine Proteases Human genes 0.000 abstract 3
- 108010022999 Serine Proteases Proteins 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 230000002950 deficient Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
- C12N9/62—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from Aspergillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Mycology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Detergent Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP92810281 | 1992-04-15 | ||
| GB939305097A GB9305097D0 (en) | 1993-03-12 | 1993-03-12 | Noval fungal protease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY2507B1 true CY2507B1 (en) | 2005-12-23 |
Family
ID=26132501
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY0500015A CY2507B1 (en) | 1992-04-15 | 2005-02-22 | Novel fungal protease |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0574347B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP3424840B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR100270644B1 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE252156T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU663173B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2093950C (cg-RX-API-DMAC7.html) |
| CY (1) | CY2507B1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE69333249T2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK0574347T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2208637T3 (cg-RX-API-DMAC7.html) |
| FI (1) | FI112667B (cg-RX-API-DMAC7.html) |
| HU (1) | HU219809B (cg-RX-API-DMAC7.html) |
| IL (2) | IL170763A (cg-RX-API-DMAC7.html) |
| MX (1) | MX9302202A (cg-RX-API-DMAC7.html) |
| NO (1) | NO315379B1 (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ247397A (cg-RX-API-DMAC7.html) |
| PT (1) | PT574347E (cg-RX-API-DMAC7.html) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5821350A (en) * | 1995-11-01 | 1998-10-13 | Nexia Biotechnologies, Inc. | Aspergillus niger beta-galactosidase gene |
| CN1160465C (zh) * | 1995-12-15 | 2004-08-04 | 诺沃奇梅兹有限公司 | 其中areA、pepC和/或pepE基因已被灭活的真菌 |
| DK0894126T3 (da) | 1996-03-27 | 2006-06-12 | Novozymes As | Alkalisk phosphatase-deficient trådformet svamp |
| AU3256397A (en) * | 1996-06-05 | 1998-01-05 | Gist-Brocades B.V. | Fungal metallo protease genes |
| JPH1016992A (ja) * | 1996-07-04 | 1998-01-20 | Toagosei Co Ltd | 接着剤用容器 |
| US6806062B1 (en) | 1998-10-05 | 2004-10-19 | Novozymes A/S | Fungal transcriptional activator useful in methods for producing polypeptides |
| ATE469223T1 (de) | 2000-03-14 | 2010-06-15 | Novozymes As | Pilz transkriptionsaktivator zur verwendung in verfahren zur herstellung von polypeptiden |
| CN101292024B (zh) * | 2005-10-17 | 2012-04-18 | 诺维信公司 | 用于表达抗体的真菌突变体的用途 |
| US8633010B2 (en) | 2007-12-06 | 2014-01-21 | Novozymes A/S | Fungal PepC inhibitor |
| US8986974B2 (en) * | 2009-12-18 | 2015-03-24 | Novozymes, Inc. | Methods for producing polypeptidies in protease-deficient mutants of trichoderma |
| MD4186C1 (ro) * | 2012-02-20 | 2013-06-30 | Институт Микробиологии И Биотехнологии Академии Наук Молдовы | Tulpină de fungi Fusarium gibbosum - producătoare de proteaze acide şi neutre, xilanaze şi b-glucozidaze |
| WO2015004241A2 (en) | 2013-07-10 | 2015-01-15 | Novartis Ag | Multiple proteases deficient filamentous fungal cells and methods of use thereof |
| US10619144B2 (en) | 2013-08-23 | 2020-04-14 | Novozymes A/S | Regulated PepC expression |
| WO2016012468A1 (en) | 2014-07-21 | 2016-01-28 | Novartis Ag | Production of glycoproteins with mammalian-like n-glycans in filamentous fungi |
| CN116121151A (zh) * | 2023-03-20 | 2023-05-16 | 广东溢多利生物科技股份有限公司 | 黑曲霉突变株anpep15m1及其应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1333777C (en) * | 1988-07-01 | 1995-01-03 | Randy M. Berka | Aspartic proteinase deficient filamentous fungi |
-
1993
- 1993-04-06 EP EP93810243A patent/EP0574347B1/en not_active Expired - Lifetime
- 1993-04-06 PT PT93810243T patent/PT574347E/pt unknown
- 1993-04-06 ES ES93810243T patent/ES2208637T3/es not_active Expired - Lifetime
- 1993-04-06 DE DE69333249T patent/DE69333249T2/de not_active Expired - Lifetime
- 1993-04-06 AT AT93810243T patent/ATE252156T1/de active
- 1993-04-06 DK DK93810243T patent/DK0574347T3/da active
- 1993-04-08 FI FI931634A patent/FI112667B/fi not_active IP Right Cessation
- 1993-04-13 CA CA002093950A patent/CA2093950C/en not_active Expired - Lifetime
- 1993-04-14 JP JP08663293A patent/JP3424840B2/ja not_active Expired - Lifetime
- 1993-04-14 KR KR1019930006178A patent/KR100270644B1/ko not_active Expired - Lifetime
- 1993-04-14 IL IL170763A patent/IL170763A/en not_active IP Right Cessation
- 1993-04-14 NO NO19931368A patent/NO315379B1/no not_active IP Right Cessation
- 1993-04-14 IL IL105383A patent/IL105383A0/xx not_active IP Right Cessation
- 1993-04-14 HU HU9301087A patent/HU219809B/hu unknown
- 1993-04-14 NZ NZ247397A patent/NZ247397A/en not_active IP Right Cessation
- 1993-04-15 AU AU36959/93A patent/AU663173B2/en not_active Expired
- 1993-04-15 MX MX9302202A patent/MX9302202A/es unknown
-
2003
- 2003-02-03 JP JP2003026301A patent/JP3636455B2/ja not_active Expired - Lifetime
-
2005
- 2005-02-22 CY CY0500015A patent/CY2507B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003235591A (ja) | 2003-08-26 |
| NZ247397A (en) | 1995-08-28 |
| FI931634L (fi) | 1993-10-16 |
| DE69333249D1 (de) | 2003-11-20 |
| JPH0646863A (ja) | 1994-02-22 |
| KR100270644B1 (ko) | 2000-11-01 |
| IL105383A0 (en) | 1993-08-18 |
| CA2093950C (en) | 2006-05-09 |
| FI931634A0 (fi) | 1993-04-08 |
| HU219809B (hu) | 2001-08-28 |
| HUT67800A (en) | 1995-05-29 |
| JP3424840B2 (ja) | 2003-07-07 |
| DK0574347T3 (da) | 2004-01-26 |
| AU663173B2 (en) | 1995-09-28 |
| PT574347E (pt) | 2004-02-27 |
| EP0574347A3 (cg-RX-API-DMAC7.html) | 1994-04-13 |
| JP3636455B2 (ja) | 2005-04-06 |
| EP0574347A2 (en) | 1993-12-15 |
| FI112667B (fi) | 2003-12-31 |
| DE69333249T2 (de) | 2004-07-29 |
| MX9302202A (es) | 1994-04-29 |
| NO931368L (no) | 1993-10-18 |
| ATE252156T1 (de) | 2003-11-15 |
| IL170763A (en) | 2007-10-31 |
| AU3695993A (en) | 1993-10-21 |
| ES2208637T3 (es) | 2004-06-16 |
| NO931368D0 (no) | 1993-04-14 |
| EP0574347B1 (en) | 2003-10-15 |
| KR930021783A (ko) | 1993-11-23 |
| NO315379B1 (no) | 2003-08-25 |
| HU9301087D0 (en) | 1993-06-28 |
| CA2093950A1 (en) | 1993-10-16 |
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