CY2008001I2 - Antiviral compounds - Google Patents

Antiviral compounds

Info

Publication number
CY2008001I2
CY2008001I2 CY200800001C CY2008001C CY2008001I2 CY 2008001 I2 CY2008001 I2 CY 2008001I2 CY 200800001 C CY200800001 C CY 200800001C CY 2008001 C CY2008001 C CY 2008001C CY 2008001 I2 CY2008001 I2 CY 2008001I2
Authority
CY
Cyprus
Prior art keywords
antiviral compounds
antiviral
compounds
Prior art date
Application number
CY200800001C
Other languages
English (en)
Other versions
CY2008001I1 (el
Original Assignee
The Wellcome Foundation Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Wellcome Foundation Limited filed Critical The Wellcome Foundation Limited
Publication of CY2008001I2 publication Critical patent/CY2008001I2/el
Publication of CY2008001I1 publication Critical patent/CY2008001I1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Plant Substances (AREA)
CY200800001C 1987-05-30 2008-01-25 Antiviral compounds CY2008001I1 (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878712745A GB8712745D0 (en) 1987-05-30 1987-05-30 Antiviral compounds

Publications (2)

Publication Number Publication Date
CY2008001I2 true CY2008001I2 (el) 2009-11-04
CY2008001I1 CY2008001I1 (el) 2009-11-04

Family

ID=10618179

Family Applications (2)

Application Number Title Priority Date Filing Date
CY200197A CY2001A (en) 1987-05-30 1997-12-05 Antiviral compounds
CY200800001C CY2008001I1 (el) 1987-05-30 2008-01-25 Antiviral compounds

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY200197A CY2001A (en) 1987-05-30 1997-12-05 Antiviral compounds

Country Status (31)

Country Link
US (2) US5424295A (el)
EP (1) EP0294114B1 (el)
JP (1) JP2667873B2 (el)
KR (1) KR970009474B1 (el)
CN (1) CN1020107C (el)
AT (1) ATE142636T1 (el)
AU (1) AU622403B2 (el)
CA (1) CA1330990C (el)
CS (1) CS277006B6 (el)
CY (2) CY2001A (el)
DD (2) DD282694A5 (el)
DE (2) DE3855522T2 (el)
DK (1) DK171670B1 (el)
ES (1) ES2091750T3 (el)
FI (1) FI89805C (el)
GB (1) GB8712745D0 (el)
GR (1) GR3021257T3 (el)
HK (1) HK78497A (el)
HU (2) HU205001B (el)
IL (1) IL86531A (el)
LU (1) LU91370I2 (el)
MC (1) MC1935A1 (el)
MY (1) MY103567A (el)
NL (1) NL300302I2 (el)
NO (2) NO172543C (el)
NZ (1) NZ224813A (el)
PH (1) PH27292A (el)
PL (1) PL157684B1 (el)
PT (1) PT87592B (el)
SA (1) SA99200688A (el)
ZA (2) ZA883829B (el)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8712745D0 (en) * 1987-05-30 1987-07-01 Wellcome Found Antiviral compounds
US6060459A (en) * 1987-10-28 2000-05-09 Pro-Neuron, Inc. Enhancing blood cell count with oxypurine nucleosides
DD293498A5 (de) * 1989-07-20 1991-09-05 Zi Fuer Molekularbiologie Der Adw,De Verfahren zur herstellung eines mittels fuer die behandlung oder prophylaxe von hepatits-infektionen bei mensch und tier
US6337209B1 (en) 1992-02-26 2002-01-08 Glaxo Wellcome Inc. Molecular constructs containing a carcinoembryonic antigen regulatory sequence
GB8919607D0 (en) 1989-08-30 1989-10-11 Wellcome Found Novel entities for cancer therapy
KR910007655A (ko) * 1989-10-03 1991-05-30 엠. 피. 잭슨 치료용 뉴클레오시드
US5206351A (en) * 1990-06-15 1993-04-27 Ash Stevens, Inc. Process for the preparation of 2-amino (2,3,5-tri-o-benzyl-beta-d-arabinofuranosyl)adenine
GB9015914D0 (en) * 1990-07-19 1990-09-05 Wellcome Found Heterocyclic compounds
US5283331A (en) * 1990-12-20 1994-02-01 Nippon Kayaku Kabushiki Kaisha 2-halogeno-oxetanocin A and phosphoric ester thereof
GB9104165D0 (en) * 1991-02-27 1991-04-17 Wellcome Found Novel entities for hiv therapy
US5961987A (en) * 1996-10-31 1999-10-05 University Of Iowa Research Foundation Ocular protein stimulants
JP3619017B2 (ja) 1998-06-24 2005-02-09 日本臓器製薬株式会社 新規アラビノシルアデニン誘導体
US6653318B1 (en) 1999-07-21 2003-11-25 Yale University 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use
DE60121425T2 (de) * 2000-02-18 2007-02-01 Southern Research Institute, Birmingham Verfahren zur Herstellung von 2-Chlor-9-(2-deoxy-2-flour-ß-D-arabinofuranosyl)-9H-purin-6-amin
US6753322B2 (en) * 2000-06-06 2004-06-22 Pfizer Inc 2-aminocarbonyl-9H-purine derivatives
JP3421330B2 (ja) * 2000-11-02 2003-06-30 持田製薬株式会社 ビダラビン注射用乾燥製剤
MXPA04004966A (es) 2001-11-27 2006-03-21 Anadys Pharmaceuticals Inc Nucleosidos de 3-beta-d-ribofuranoziltiazol(4,5-d(pirimidina y uso de los mismos.
US7321033B2 (en) * 2001-11-27 2008-01-22 Anadys Pharmaceuticals, Inc. 3-B-D-ribofuranosylthiazolo [4,5-d] pyrimidine nucleosides and uses thereof
WO2004028481A2 (en) * 2002-09-30 2004-04-08 Genelabs Technologies, Inc. Nucleoside derivatives for treating hepatitis c virus infection
AR052995A1 (es) 2004-12-17 2007-04-18 Anadys Pharmaceuticals Inc Compuestos de 3h-oxazolo y 3h-tiazolo[4, 5 - d]pirimidin-2-ona3, 5-disustituidos y 3, 5, 7-trisustituidos con actividad inmunomoduladora, sus profarmacos, composiciones farmaceuticas que los contienen y su empleo en el tratamiento de enfermedades de origen viral
US20060178512A1 (en) * 2005-02-04 2006-08-10 Cheruthur Govindan Method for preparing amino acid esters of nucleoside analogues
KR20080090400A (ko) 2005-11-21 2008-10-08 애나디스 파마슈티칼스, 인코포레이티드 5-아미노-3Ｈ-티아졸로[4,5-ｄ]피리미딘-2-온의 제조 방법
US7709448B2 (en) * 2006-06-22 2010-05-04 Anadys Pharmaceuticals, Inc. Prodrugs of 5-amino-3-(3′-deoxy-β-D-ribofuranosyl)-thiazolo[4,5-d]pyrimidin-2,7-dione
DE602007012881D1 (en) 2006-07-18 2011-04-14 Anadys Pharmaceuticals Inc Carbonat- und carbamat-prodrugs von thiazolo ä4,5-dü-pyrimidinen
CN101092441A (zh) * 2007-07-17 2007-12-26 北京本草天源药物研究院 一种奈拉滨的合成方法
US7846912B2 (en) * 2007-09-13 2010-12-07 Protia, Llc Deuterium-enriched nelarabine
CN101768197A (zh) * 2008-12-29 2010-07-07 北京德众万全药物技术开发有限公司 一种奈拉滨的制备方法
CN103665076B (zh) * 2012-08-30 2018-01-09 上海阳帆医药科技有限公司 奈拉滨的制备方法
CN104892709B (zh) * 2015-06-04 2018-01-19 新乡学院 一种合成奈拉滨的方法
WO2018133835A1 (en) * 2017-01-20 2018-07-26 National Institute Of Biological Sciences, Beijing Nucleoside analogue regulating mammalian circadian rhythm
WO2022258014A1 (zh) * 2021-06-09 2022-12-15 正大天晴药业集团股份有限公司 用于制备奈拉滨的重组基因工程菌及其应用
CN115279891B (zh) * 2021-06-09 2024-11-22 正大天晴药业集团股份有限公司 用于制备奈拉滨的重组基因工程菌及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759011A (fr) * 1969-11-17 1971-05-17 Wellcome Found Aminopurines
US3758684A (en) * 1971-09-07 1973-09-11 Burroughs Wellcome Co Treating dna virus infections with amino purine derivatives
US4055717A (en) * 1976-05-17 1977-10-25 Parke, Davis & Company 9-(3-O-Acyl-β-D-arabinofuranosyl)adenine compounds, 9-(2,3-di-O-acyl-β-D-arabinofuranosyl)-adenine compounds, and method for their production
US4048432A (en) * 1976-05-17 1977-09-13 Parke, Davis & Company 9-(3,5-Di-O-acyl-β-D-arabinofuranosyl)adenine compounds and method for their production
US4055718A (en) * 1976-05-17 1977-10-25 Parke, Davis & Company 9-(2-O-Acyl-β-D-arabinofuranosyl)-adenine compounds and method for their production
JPS6053941B2 (ja) * 1977-08-10 1985-11-28 日本電気株式会社 バイアスライト駆動方式
US4371613A (en) * 1977-08-10 1983-02-01 Ajinomoto Company Incorporated Method for producing purine arabinosides
JPS5515716A (en) * 1978-07-18 1980-02-04 Ajinomoto Co Inc Production of purine arabinoside
GB1573777A (en) * 1977-11-03 1980-08-28 Wellcome Found 9-d-arabinonucleosides and an enzymatic process for their preparation
US4495180A (en) * 1982-06-21 1985-01-22 Merck & Co., Inc. Prodrugs of Ara-A an antiviral agent
JPS58225097A (ja) * 1982-06-23 1983-12-27 Yamasa Shoyu Co Ltd ヌクレオシド５′−アルキルもしくはアルケニルりん酸
IE73219B1 (en) * 1985-03-16 1997-05-07 Wellcome Found Therapeutic nucleosides
GB8712745D0 (en) * 1987-05-30 1987-07-01 Wellcome Found Antiviral compounds

Also Published As

Publication number Publication date
AU622403B2 (en) 1992-04-09
DE3855522T2 (de) 1997-02-06
AU1671888A (en) 1988-12-01
LU91370I2 (fr) 2007-12-10
NO2007016I1 (no) 2008-01-14
MY103567A (en) 1993-08-28
DK289788A (da) 1988-12-01
DE3855522D1 (de) 1996-10-17
NL300302I1 (nl) 2008-01-02
PL157684B1 (pl) 1992-06-30
NO172543C (no) 1993-08-04
ZA897598B (en) 1990-01-31
FI89805C (fi) 1993-11-25
DD282694A5 (de) 1990-09-19
HUT47129A (en) 1989-01-30
IL86531A (en) 1993-07-08
EP0294114A2 (en) 1988-12-07
US5539098A (en) 1996-07-23
HU205001B (en) 1992-03-30
DE122008000003I2 (de) 2010-02-04
CS8803635A2 (en) 1990-09-12
NO172543B (no) 1993-04-26
PT87592B (pt) 1992-09-30
JP2667873B2 (ja) 1997-10-27
DE122008000003I1 (de) 2008-04-17
NO882357L (no) 1988-12-01
HK78497A (en) 1997-06-20
FI882511A0 (fi) 1988-05-27
KR880013967A (ko) 1988-12-22
EP0294114B1 (en) 1996-09-11
KR970009474B1 (ko) 1997-06-13
ATE142636T1 (de) 1996-09-15
PL272729A1 (en) 1989-02-06
FI882511L (fi) 1988-12-01
HU199870B (en) 1990-03-28
IL86531A0 (en) 1988-11-15
DD293962A5 (de) 1991-09-19
EP0294114A3 (en) 1990-01-24
ES2091750T3 (es) 1996-11-16
ZA883829B (en) 1990-01-31
FI89805B (fi) 1993-08-13
SA99200688A (ar) 2005-12-03
PH27292A (en) 1993-05-04
US5424295A (en) 1995-06-13
CY2001A (en) 1997-12-05
GB8712745D0 (en) 1987-07-01
DK289788D0 (da) 1988-05-27
DK171670B1 (da) 1997-03-10
NZ224813A (en) 1991-04-26
NO882357D0 (no) 1988-05-27
NO2007016I2 (no) 2008-06-23
GR3021257T3 (en) 1997-01-31
MC1935A1 (fr) 1989-05-19
PT87592A (pt) 1989-05-31
CA1330990C (en) 1994-07-26
CN1020107C (zh) 1993-03-17
CN1031233A (zh) 1989-02-22
CS277006B6 (en) 1992-11-18
JPS63310831A (ja) 1988-12-19
CY2008001I1 (el) 2009-11-04
NL300302I2 (nl) 2008-05-01
HU895829D0 (en) 1990-01-28

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