CY1123875T1 - Συνθεση και μεθοδος για τη δεσμευση ακεταλδεϋδης στο στομαχι - Google Patents

Συνθεση και μεθοδος για τη δεσμευση ακεταλδεϋδης στο στομαχι

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Publication number
CY1123875T1
CY1123875T1 CY20211100066T CY211100066T CY1123875T1 CY 1123875 T1 CY1123875 T1 CY 1123875T1 CY 20211100066 T CY20211100066 T CY 20211100066T CY 211100066 T CY211100066 T CY 211100066T CY 1123875 T1 CY1123875 T1 CY 1123875T1
Authority
CY
Cyprus
Prior art keywords
stomach
composition
acetaldehyde
compound
present
Prior art date
Application number
CY20211100066T
Other languages
English (en)
Inventor
Osmo Suovaniemi
Ville Salaspuro
Martti Marvola
Mikko Salaspuro
Original Assignee
Biohit Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biohit Oyj filed Critical Biohit Oyj
Publication of CY1123875T1 publication Critical patent/CY1123875T1/el

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/131—Amines acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
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  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Abstract

Η παρούσα εφεύρεση αναφέρεται σε μια μη τοξική σύνθεση η οποία δεσμεύει την ακεταλδεΰδη που υπάρχει στο στομάχι, το έντερο ή/και το κόλον. Η σύνθεση περιλαμβάνει μία ή περισσότερες δεσμεύουσες την ακεταλδεΰδη ενώσεις που περιλαμβάνουν μία ή περισσότερες ελεύθερες σουλφυδρυλο ή/και αμινο ομάδες. Η ένωση(-εις) αναμιγνύεται με έναν μη τοξικό φορέα που πραγματοποιεί παρατεταμένη απελευθέρωση της ρηθείσας ένωσης(-εων) στο γαστροεντερικό σωλήνα. Αυτές οι συνθέσεις είναι ωφέλιμες ιδιαίτερα σε ασθενείς που έχουν ατροφική γαστρίτιδα ή αχλωρυδρικό στομάχι ή στομάχι με χαμηλά επίπεδα οξέων.
CY20211100066T 2006-05-22 2021-01-27 Συνθεση και μεθοδος για τη δεσμευση ακεταλδεϋδης στο στομαχι CY1123875T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80212006P 2006-05-22 2006-05-22
FI20060501A FI20060501L (fi) 2006-05-22 2006-05-22 Koostumus ja menetelmä asetaldehydin sitomiseksi vatsassa
PCT/FI2007/050287 WO2007135241A2 (en) 2006-05-22 2007-05-22 Composition and method for binding acetaldehyde in stomach

Publications (1)

Publication Number Publication Date
CY1123875T1 true CY1123875T1 (el) 2022-05-27

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CY20211100066T CY1123875T1 (el) 2006-05-22 2021-01-27 Συνθεση και μεθοδος για τη δεσμευση ακεταλδεϋδης στο στομαχι

Country Status (16)

Country Link
US (2) US20090253793A1 (el)
EP (2) EP2034982A1 (el)
JP (5) JP2009538832A (el)
KR (4) KR20090030272A (el)
CN (2) CN101668522B (el)
CY (1) CY1123875T1 (el)
DK (1) DK2049097T3 (el)
EA (2) EA021063B1 (el)
ES (1) ES2845635T3 (el)
FI (1) FI20060501L (el)
HU (1) HUE052428T2 (el)
LT (1) LT2049097T (el)
PL (1) PL2049097T3 (el)
PT (1) PT2049097T (el)
SI (1) SI2049097T1 (el)
WO (2) WO2007135241A2 (el)

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EA200802360A1 (ru) 2010-02-26
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