DK2049097T3 - Sammensætning og fremgangsmåde til at binde acetaldehyd i maven - Google Patents

Sammensætning og fremgangsmåde til at binde acetaldehyd i maven Download PDF

Info

Publication number
DK2049097T3
DK2049097T3 DK07730774.2T DK07730774T DK2049097T3 DK 2049097 T3 DK2049097 T3 DK 2049097T3 DK 07730774 T DK07730774 T DK 07730774T DK 2049097 T3 DK2049097 T3 DK 2049097T3
Authority
DK
Denmark
Prior art keywords
stomach
composition
binding acetaldehyde
acetaldehyde
binding
Prior art date
Application number
DK07730774.2T
Other languages
English (en)
Inventor
Osmo Suovaniemi
Ville Salaspuro
Martti Marvola
Mikko Salaspuro
Original Assignee
Biohit Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biohit Oyj filed Critical Biohit Oyj
Application granted granted Critical
Publication of DK2049097T3 publication Critical patent/DK2049097T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/131Amines acyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846Poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/485Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Dairy Products (AREA)
  • Confectionery (AREA)
  • Non-Alcoholic Beverages (AREA)
DK07730774.2T 2006-05-22 2007-05-22 Sammensætning og fremgangsmåde til at binde acetaldehyd i maven DK2049097T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80212006P 2006-05-22 2006-05-22
FI20060501A FI20060501L (fi) 2006-05-22 2006-05-22 Koostumus ja menetelmä asetaldehydin sitomiseksi vatsassa
PCT/FI2007/050287 WO2007135241A2 (en) 2006-05-22 2007-05-22 Composition and method for binding acetaldehyde in stomach

Publications (1)

Publication Number Publication Date
DK2049097T3 true DK2049097T3 (da) 2021-01-25

Family

ID=38436750

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07730774.2T DK2049097T3 (da) 2006-05-22 2007-05-22 Sammensætning og fremgangsmåde til at binde acetaldehyd i maven

Country Status (16)

Country Link
US (2) US20090253793A1 (da)
EP (2) EP2034982A1 (da)
JP (5) JP2009538832A (da)
KR (4) KR20090030272A (da)
CN (2) CN101668522B (da)
CY (1) CY1123875T1 (da)
DK (1) DK2049097T3 (da)
EA (2) EA021063B1 (da)
ES (1) ES2845635T3 (da)
FI (1) FI20060501L (da)
HU (1) HUE052428T2 (da)
LT (1) LT2049097T (da)
PL (1) PL2049097T3 (da)
PT (1) PT2049097T (da)
SI (1) SI2049097T1 (da)
WO (2) WO2007135241A2 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110171296A1 (en) * 2000-10-30 2011-07-14 Biohit Oyj Method and preparation for binding acetaldehyde in saliva, the stomach and the large intestine
US20070077297A1 (en) 2004-09-30 2007-04-05 Scolr Pharma, Inc. Modified release ibuprofen dosage form
FI20060501L (fi) * 2006-05-22 2007-11-23 Biohit Oyj Koostumus ja menetelmä asetaldehydin sitomiseksi vatsassa
JP5496616B2 (ja) * 2009-11-18 2014-05-21 フロイント産業株式会社 大腸ドラッグデリバリーシステム製剤
DE102011001768A1 (de) 2011-04-04 2012-10-04 Gunnar Frank Präparat oder Nahrungsergänzungsmittel
FI20115377A (fi) * 2011-04-18 2012-10-19 Biohit Oyj Ylempien hengitys- ja ruoansulatuselinten mikrobi-infektioihin liittyvissä tiloissa käytettäväksi tarkoitettuja lääketieteellisiä tuotteita
ITMI20120847A1 (it) * 2012-05-16 2013-11-17 Labomar S R L Formulazione per sostanze a bassa biodisponibilità.
FI129157B (fi) * 2012-05-28 2021-08-13 Biohit Oyj Koostumus käytettäväksi vakavien päänsärkyjen esiintymistiheyden pienentämiseksi tai niiden vähentämiseksi
JP2016514120A (ja) * 2013-03-12 2016-05-19 ビオヒット・ユルキネン・オサケユキテュアBiohit Oyj 胃腸管においてアルデヒドを結合するための経口投与用組成物
BR112015006048A2 (pt) * 2013-03-12 2017-07-04 Biohit Oyj composição encapsulada para ligação com aldeídos no estômago
FI20135503L (fi) * 2013-05-13 2014-11-14 Biohit Oyj Kysteiini tai sen johdannainen atrofisen gastriitin hoitamiseen
FI20145217A (fi) * 2014-03-06 2015-09-07 Biohit Oyj Koostumus aldehydien ja vapaiden radikaalien sitomiseksi ruoansulatuskanavassa
CN105267267A (zh) * 2014-06-05 2016-01-27 樊伟 L-半胱氨酸组合物在预防、清除(或消除)吸烟、饮酒时所产生的致癌因素乙醛的应用
FI127823B (en) * 2015-03-06 2019-03-15 Biohit Oyj A composition for preventing the symptoms of a hangover
JP6009050B1 (ja) * 2015-08-21 2016-10-19 国立大学法人東北大学 飲酒による悪酔いまたは二日酔いの軽減または予防剤
US11717554B2 (en) * 2019-09-19 2023-08-08 Max R&D Llc Method for preventing or treating hangover symptom(s) associated with consumption of alcoholic beverage(s)

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1500300A (en) * 1975-01-06 1978-02-08 Ciba Geigy Ag Pharmaceutical preparation for the treatment of circulatory disorders
PH22818A (en) * 1986-02-18 1989-01-19 Takeda Chemical Industries Ltd Composition and method for reducing acetaldehyde toxicity
SE462779B (sv) * 1988-10-10 1990-09-03 Lejus Medical Ab Farmaceutisk komposition innehaallande n-acetylcystein i en kaerna belagd med hydroxipropylmetylcellulosaftalat
JPH0421635A (ja) 1990-05-16 1992-01-24 Suntory Ltd アセトアルデヒドの毒性抑制剤およびアセトアルデヒドの毒性抑制に有効な飲食物
JPH0789876A (ja) * 1993-09-20 1995-04-04 Shiseido Co Ltd 徐放性製剤
US5965161A (en) * 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
FI97304C (fi) * 1994-11-16 1996-11-25 Locus Genex Oy Menetelmä mahasyövän riskin seulonnaksi
JP2000507613A (ja) * 1996-11-01 2000-06-20 アイレックス・オンコロジー・インコーポレイテッド Dfmo含有持続放出配合物
US20020068365A1 (en) * 1998-07-28 2002-06-06 Eric H. Kuhrts Controlled release nitric oxide producing agents
US6303607B1 (en) * 1998-09-10 2001-10-16 Cv Therapeutics, Inc. Method for administering a sustained release ranolanolazine formulation
DZ2937A1 (fr) * 1998-11-12 2004-03-15 Smithkline Beecham Plc Compositions nouvelles de sensibilidants à l'insuline.
JP2000178194A (ja) * 1998-12-18 2000-06-27 Pola Chem Ind Inc 徐放性製剤
FI121528B (fi) * 2000-10-30 2010-12-31 Biohit Oyj Farmaseuttinen koostumus syöpään sairastumisen riskin vähentämiseen paikallisesti sitomalla asetaldehydi syljessä, mahalaukussa tai paksusuolessa
JP3715529B2 (ja) * 2000-12-19 2005-11-09 雅嗣 田中 アルコール代謝促進剤
DE10224170A1 (de) * 2002-05-31 2003-12-11 Desitin Arzneimittel Gmbh Pharmazeutische Zusammensetzung mit verzögerter Wirkstofffreisetzung
DE10224655B4 (de) * 2002-06-03 2005-03-10 Deuter Sport & Leder Rucksack mit integriertem Kleinkindersitz
FI119571B (fi) * 2002-09-06 2008-12-31 Biohit Oyj Menetelmä esofagiitin tai Barrettin ruokatorven riskin osoittamiseksi yksilöllä
WO2004066924A2 (en) * 2003-01-24 2004-08-12 Andrx Labs Llc Novel pharmaceutical formulation containing a proton pump inhibitor and an antacid
US20050271754A1 (en) * 2004-06-07 2005-12-08 Cochrane Patrick W Composition for prevention or treatment of an alcohol hangover
JP5654726B2 (ja) * 2004-10-08 2015-01-14 ビオヒット・ユルキネン・オサケユキテュアBiohit Oyj 唾液中のアルデヒド類を結合するための方法および製剤
FI122914B (fi) * 2005-04-01 2012-08-31 Biohit Oyj Elintarvikekoostumus asetaldehydin sitomiseksi suussa ja ruoansulatuskanavassa ja menetelmä koostumuksen valmistamiseksi
FI20060501L (fi) * 2006-05-22 2007-11-23 Biohit Oyj Koostumus ja menetelmä asetaldehydin sitomiseksi vatsassa

Also Published As

Publication number Publication date
SI2049097T1 (sl) 2021-05-31
JP5394235B2 (ja) 2014-01-22
JP6178657B2 (ja) 2017-08-09
CN101668522B (zh) 2015-06-24
EP2049097A2 (en) 2009-04-22
LT2049097T (lt) 2021-02-10
EA200802360A1 (ru) 2010-02-26
EP2034982A1 (en) 2009-03-18
JP2009537613A (ja) 2009-10-29
CY1123875T1 (el) 2022-05-27
WO2007135241A3 (en) 2009-09-17
KR20130099217A (ko) 2013-09-05
EP2049097B1 (en) 2020-11-04
JP2013177413A (ja) 2013-09-09
PL2049097T3 (pl) 2021-05-31
EA200802361A1 (ru) 2009-06-30
ES2845635T3 (es) 2021-07-27
PT2049097T (pt) 2021-02-04
JP2013231080A (ja) 2013-11-14
WO2007135241A2 (en) 2007-11-29
WO2007135242A1 (en) 2007-11-29
US8758812B2 (en) 2014-06-24
US20100239663A1 (en) 2010-09-23
EA019832B1 (ru) 2014-06-30
KR20090030272A (ko) 2009-03-24
CN101668522A (zh) 2010-03-10
CN101489545A (zh) 2009-07-22
FI20060501L (fi) 2007-11-23
HUE052428T2 (hu) 2021-04-28
EA021063B1 (ru) 2015-03-31
US20090253793A1 (en) 2009-10-08
KR20130020733A (ko) 2013-02-27
JP2016196500A (ja) 2016-11-24
JP2009538832A (ja) 2009-11-12
FI20060501A0 (fi) 2006-05-22
KR20090015986A (ko) 2009-02-12

Similar Documents

Publication Publication Date Title
DK2049097T3 (da) Sammensætning og fremgangsmåde til at binde acetaldehyd i maven
CY2020009I1 (el) Δεσμευτικοι παραγοντες σκληροστινης
NO20190583A1 (no) Kompletteringssystem for anvendelse i en brønn og fremgangsmåte for komplettering av en brønn
DK2079355T3 (da) Fremgangsmåde og system til brilleordination
HK1217203A1 (zh) 白介素- 的結合成員
DK2099823T4 (da) Målbindingsmiddelvarianter og anvendelser deraf
DK2046362T3 (da) Formulering omfattende valleprotein og hydrolysater til forbedring af muskelrekuperation
DK2147315T3 (da) Diabetesrelaterede biomarkører og fremgangsmåder til anvendelse deraf
DK2087002T3 (da) Sammensætninger og fremgangsmåder til binding af sphingosin-1-phosphat
DK2010501T3 (da) Imidazolbaserede forbindelser, sammensætninger omfattende disse og fremgangsmåder for deres anvendelse
DK2167963T3 (da) Polymerbærere til immunhistokemi og in situ-hybridisering
DK1997291T3 (da) Metode og anordning til sikker godkendelse
EP2114272A4 (en) DEVICE FOR STRENGTHENING THE VERTEBRAL COLUMN AND ASSOCIATED METHOD
DK2222675T3 (da) 5-anilinoimidazopyridiner og fremgangsmåder til deres anvendelse
DK2066339T3 (da) Sammensætninger og fremgangsmåder til forstærkning af immunreaktioner
DK2010676T3 (da) Fremgangsmåde og kit til molekylær kromosomal kvantificering
DK2066817T3 (da) Molekylære afbrydere og fremgangsmåder til anvendelse deraf
DK2131939T3 (da) Filteranordning og fremgangsmåde
EP1764799A4 (en) READING DEVICE, PROGRAM, AND READING METHOD
DK1988090T3 (da) Imidazol-5-carboxylsyrederivater, fremgangsmåder til fremstilling af disse og anvendelse deraf
DK1976884T3 (da) Anti-ephrinb2-antistoffer og fremgangsmåder til anvendelse deraf.
DK2217875T3 (da) Brygfremgangsmåde og bryggerianlæg
EP2160891A4 (en) DIGITAL READING DEVICE AND METHOD
DK1999403T3 (da) Multikoblingssystem og fremgangsmåde relateret dertil
NO20075424L (no) Fremgangsmate og anvendelse