DK2066817T3 - Molekylære afbrydere og fremgangsmåder til anvendelse deraf - Google Patents
Molekylære afbrydere og fremgangsmåder til anvendelse derafInfo
- Publication number
- DK2066817T3 DK2066817T3 DK07815323.6T DK07815323T DK2066817T3 DK 2066817 T3 DK2066817 T3 DK 2066817T3 DK 07815323 T DK07815323 T DK 07815323T DK 2066817 T3 DK2066817 T3 DK 2066817T3
- Authority
- DK
- Denmark
- Prior art keywords
- methods
- molecular switches
- switches
- molecular
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/30—Phosphoric diester hydrolysing, i.e. nuclease
- C12Q2521/337—Ribozyme
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/50—Other enzymatic activities
- C12Q2521/501—Ligase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/125—Sandwich assay format
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/10—Detection mode being characterised by the assay principle
- C12Q2565/101—Interaction between at least two labels
- C12Q2565/1015—Interaction between at least two labels labels being on the same oligonucleotide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82845106P | 2006-10-06 | 2006-10-06 | |
| PCT/AU2007/001517 WO2008040095A1 (en) | 2006-10-06 | 2007-10-05 | Molecular switches and methods for their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2066817T3 true DK2066817T3 (da) | 2014-10-13 |
Family
ID=39268069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07815323.6T DK2066817T3 (da) | 2006-10-06 | 2007-10-05 | Molekylære afbrydere og fremgangsmåder til anvendelse deraf |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9127311B2 (da) |
| EP (1) | EP2066817B1 (da) |
| JP (1) | JP5688507B2 (da) |
| KR (1) | KR20090098960A (da) |
| CN (1) | CN101600808B (da) |
| AU (1) | AU2007304837B2 (da) |
| BR (1) | BRPI0718137B1 (da) |
| CA (1) | CA2663164C (da) |
| DK (1) | DK2066817T3 (da) |
| ES (1) | ES2520023T3 (da) |
| IL (1) | IL197543A (da) |
| MX (1) | MX2009003193A (da) |
| WO (1) | WO2008040095A1 (da) |
| ZA (1) | ZA200901742B (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2385141T3 (da) | 2005-10-07 | 2013-10-28 | Speedx Pty Ltd | Flerkomponentnukleinsyreenzymer og fremgangsmåder til anvendelse heraf |
| EP1987166A4 (en) | 2006-02-03 | 2010-06-02 | Univ Columbia | DEOXYRIBOZYME BINARY PROBES FOR ANALYSIS OF NUCLEIC ACID |
| US9127311B2 (en) | 2006-10-06 | 2015-09-08 | Speedx Pty Ltd | Molecular switches and methods for their use |
| AU2008235256B2 (en) * | 2007-04-05 | 2014-05-15 | Speedx Pty Ltd | Nucleic acid enzymes and complexes and methods for their use |
| US9051606B2 (en) | 2010-09-10 | 2015-06-09 | Qiagen Gaithersburg, Inc. | Methods and compositions for nucleic acid detection |
| WO2012065231A1 (en) * | 2010-11-19 | 2012-05-24 | Speedx Pty Ltd | Signal amplification |
| WO2013033792A1 (en) | 2011-09-09 | 2013-03-14 | Speedx Pty Ltd | Nucleic acid enzyme substrates |
| CA2863257C (en) * | 2012-02-14 | 2021-12-14 | Cornell University | Method for relative quantification of nucleic acid sequence, expression, or copy changes, using combined nuclease, ligation, and polymerase reactions |
| EP2817421B1 (en) | 2012-02-20 | 2017-12-13 | SpeeDx Pty Ltd | Detection of nucleic acids |
| AU2013202354A1 (en) * | 2012-06-18 | 2014-01-16 | Speedx Pty Ltd | Target detection and signal amplification |
| JP2016522807A (ja) | 2013-04-18 | 2016-08-04 | バル・イラン・ユニバーシティＢａｒ Ｉｌａｎ Ｕｎｉｖｅｒｓｉｔｙ | 分子計算のための非免疫原性及び核酸分解酵素耐性核酸折り紙デバイスを含むシステム |
| CN105763200B (zh) * | 2016-02-05 | 2018-10-16 | 大连大学 | 基于dna链置换的4-10译码器设计方法 |
| CN105954957B (zh) * | 2016-05-02 | 2018-10-23 | 福建医科大学 | 基于金纳米团簇固相复合物的nand逻辑门及其构建方法 |
| EP3665305A1 (en) | 2017-08-10 | 2020-06-17 | Katholieke Universiteit Leuven | Nucleic acid enzyme sensor |
| KR20210057028A (ko) * | 2018-08-09 | 2021-05-20 | 스피디엑스 피티와이 리미티드 | 핵산의 다중 검출 |
| KR102239459B1 (ko) * | 2019-09-16 | 2021-04-12 | 한국화학연구원 | 산화 그래핀, DNAzyme 및 PNA를 포함하는 온도 센서용 조성물 및 이를 이용한 온도 센싱 방법 |
| CN112501260B (zh) * | 2020-11-27 | 2021-06-29 | 广东省科学院生态环境与土壤研究所 | 一种双酚a的检测方法、荧光检测试剂盒及其应用 |
| CN112630439A (zh) * | 2020-12-11 | 2021-04-09 | 郑州轻工业大学 | 基于纳米金的分裂型适体传感器及其制备方法和应用 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4000A (en) * | 1845-04-16 | Combined lock and latch | ||
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5176995A (en) * | 1985-03-28 | 1993-01-05 | Hoffmann-La Roche Inc. | Detection of viruses by amplification and hybridization |
| US4965188A (en) * | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4800159A (en) * | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| ATE115999T1 (de) | 1987-12-15 | 1995-01-15 | Gene Shears Pty Ltd | Ribozyme. |
| US5424413A (en) | 1992-01-22 | 1995-06-13 | Gen-Probe Incorporated | Branched nucleic acid probes |
| ES2176233T3 (es) * | 1992-12-04 | 2002-12-01 | Univ Yale | Deteccion diagnostica amplificada con ribozimas. |
| US5876924A (en) | 1994-06-22 | 1999-03-02 | Mount Sinai School Of Medicine | Nucleic acid amplification method hybridization signal amplification method (HSAM) |
| US7141665B1 (en) * | 1998-04-29 | 2006-11-28 | The Scripps Research Institute | Enzymatic DNA molecules |
| US5807718A (en) * | 1994-12-02 | 1998-09-15 | The Scripps Research Institute | Enzymatic DNA molecules |
| US5545729A (en) * | 1994-12-22 | 1996-08-13 | Hybridon, Inc. | Stabilized ribozyme analogs |
| EP0822992A4 (en) | 1995-02-27 | 2000-08-09 | Intelligene Ltd | DETECTION OF BIOMOLECULES |
| CN1261920A (zh) | 1997-04-29 | 2000-08-02 | 斯克里普斯研究学院 | 酶促dna分子 |
| IL138126A0 (en) | 1998-03-05 | 2001-10-31 | Johnson & Johnson Res Pty Ltd | Zymogenic nucleic acid detection methods and related molecules and kits |
| WO1999046388A1 (fr) * | 1998-03-12 | 1999-09-16 | Taisho Pharmaceutical Co., Ltd. | Enzyme d'acide nucleique ayant une activite de clivage d'arn allosterique sur un arn cible |
| DE19811618C1 (de) * | 1998-03-17 | 2000-08-31 | Andreas Jenne | Ribozym codierende DNA und ein Oligonucleotidsubstrat enthaltende Zusammensetzung und Verfahren zur Messung von Transkriptionsraten |
| ATE431852T1 (de) | 1998-03-27 | 2009-06-15 | Johnson & Johnson Res Pty Ltd | Diagnostische methoden basierend auf katalytischen nukleinsäuren |
| DE19915141C2 (de) | 1999-03-26 | 2002-11-21 | Artus Ges Fuer Molekularbiolog | Detektion von Nucleinsäure-Amplifikaten |
| EP1263947A2 (en) * | 2000-03-06 | 2002-12-11 | Ribozyme Pharmaceuticals, Inc. | Nucleic acid sensor molecules |
| JP3595843B2 (ja) * | 2000-10-13 | 2004-12-02 | 独立行政法人産業技術総合研究所 | Ｒｎａ分子を認識することにより他の特定の標的ｒｎａに対する切断活性を獲得する核酸酵素 |
| AU2002367785A1 (en) | 2001-11-05 | 2003-11-03 | Sirna Therapeutics, Inc | Allosteric nucleic acid sensor molecules |
| WO2005051174A2 (en) | 2003-11-21 | 2005-06-09 | The Trustees Of Columbia University In The City Of New York | Nucleic acid aptamer-based compositions and methods |
| WO2005073405A2 (en) * | 2004-01-29 | 2005-08-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Catalytic polynucleotide and its use for determination of analytes |
| US7553945B2 (en) * | 2005-08-03 | 2009-06-30 | Bowling Green State University | RNA complexes and methods of their production |
| CN101341260B (zh) * | 2005-10-07 | 2014-02-12 | 强生研究有限公司 | 多组分核酸酶及其使用方法 |
| DK2385141T3 (da) * | 2005-10-07 | 2013-10-28 | Speedx Pty Ltd | Flerkomponentnukleinsyreenzymer og fremgangsmåder til anvendelse heraf |
| US8673551B2 (en) * | 2005-12-07 | 2014-03-18 | Speedx Pty Ltd. | Methods, plasmid vectors and primers for assessing HIV viral fitness |
| EP1987166A4 (en) * | 2006-02-03 | 2010-06-02 | Univ Columbia | DEOXYRIBOZYME BINARY PROBES FOR ANALYSIS OF NUCLEIC ACID |
| US9127311B2 (en) | 2006-10-06 | 2015-09-08 | Speedx Pty Ltd | Molecular switches and methods for their use |
| AU2008235256B2 (en) | 2007-04-05 | 2014-05-15 | Speedx Pty Ltd | Nucleic acid enzymes and complexes and methods for their use |
| CA2682337C (en) * | 2007-04-06 | 2017-01-17 | Virco Bvba | Respiratory syncytial virus (rsv) viral load detection assay |
| EP2188394B1 (en) | 2007-08-13 | 2015-06-24 | University of Strathclyde | Identification of nucleic acid sequences |
| WO2010017246A1 (en) | 2008-08-04 | 2010-02-11 | University Of Maryland | Probes and methods for detecting analytes |
-
2007
- 2007-10-05 US US12/442,275 patent/US9127311B2/en not_active Expired - Fee Related
- 2007-10-05 DK DK07815323.6T patent/DK2066817T3/da active
- 2007-10-05 BR BRPI0718137A patent/BRPI0718137B1/pt active IP Right Grant
- 2007-10-05 CN CN200780037345.2A patent/CN101600808B/zh active Active
- 2007-10-05 MX MX2009003193A patent/MX2009003193A/es active IP Right Grant
- 2007-10-05 CA CA2663164A patent/CA2663164C/en active Active
- 2007-10-05 WO PCT/AU2007/001517 patent/WO2008040095A1/en active Application Filing
- 2007-10-05 ES ES07815323.6T patent/ES2520023T3/es active Active
- 2007-10-05 EP EP07815323.6A patent/EP2066817B1/en active Active
- 2007-10-05 AU AU2007304837A patent/AU2007304837B2/en not_active Ceased
- 2007-10-05 KR KR1020097009384A patent/KR20090098960A/ko not_active Application Discontinuation
- 2007-10-05 ZA ZA200901742A patent/ZA200901742B/xx unknown
- 2007-10-05 JP JP2009530739A patent/JP5688507B2/ja not_active Expired - Fee Related
-
2009
- 2009-03-11 IL IL197543A patent/IL197543A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| JP5688507B2 (ja) | 2015-03-25 |
| AU2007304837B2 (en) | 2011-09-29 |
| CN101600808A (zh) | 2009-12-09 |
| EP2066817B1 (en) | 2014-07-30 |
| CA2663164C (en) | 2016-07-12 |
| KR20090098960A (ko) | 2009-09-18 |
| AU2007304837A1 (en) | 2008-04-10 |
| BRPI0718137B1 (pt) | 2016-05-10 |
| JP2010505394A (ja) | 2010-02-25 |
| ZA200901742B (en) | 2010-06-30 |
| US9127311B2 (en) | 2015-09-08 |
| IL197543A0 (en) | 2009-12-24 |
| WO2008040095A1 (en) | 2008-04-10 |
| BRPI0718137A2 (pt) | 2013-11-05 |
| US20100136536A1 (en) | 2010-06-03 |
| EP2066817A4 (en) | 2011-02-09 |
| ES2520023T3 (es) | 2014-11-11 |
| CA2663164A1 (en) | 2008-04-10 |
| EP2066817A1 (en) | 2009-06-10 |
| CN101600808B (zh) | 2014-07-09 |
| IL197543A (en) | 2016-10-31 |
| MX2009003193A (es) | 2009-08-13 |
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