DK2066817T3 - Molecular switches and methods for using them - Google Patents
Molecular switches and methods for using themInfo
- Publication number
- DK2066817T3 DK2066817T3 DK07815323.6T DK07815323T DK2066817T3 DK 2066817 T3 DK2066817 T3 DK 2066817T3 DK 07815323 T DK07815323 T DK 07815323T DK 2066817 T3 DK2066817 T3 DK 2066817T3
- Authority
- DK
- Denmark
- Prior art keywords
- methods
- molecular switches
- switches
- molecular
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/30—Phosphoric diester hydrolysing, i.e. nuclease
- C12Q2521/337—Ribozyme
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/50—Other enzymatic activities
- C12Q2521/501—Ligase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/125—Sandwich assay format
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/10—Detection mode being characterised by the assay principle
- C12Q2565/101—Interaction between at least two labels
- C12Q2565/1015—Interaction between at least two labels labels being on the same oligonucleotide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82845106P | 2006-10-06 | 2006-10-06 | |
| PCT/AU2007/001517 WO2008040095A1 (en) | 2006-10-06 | 2007-10-05 | Molecular switches and methods for their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2066817T3 true DK2066817T3 (en) | 2014-10-13 |
Family
ID=39268069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07815323.6T DK2066817T3 (en) | 2006-10-06 | 2007-10-05 | Molecular switches and methods for using them |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9127311B2 (en) |
| EP (1) | EP2066817B1 (en) |
| JP (1) | JP5688507B2 (en) |
| KR (1) | KR20090098960A (en) |
| CN (1) | CN101600808B (en) |
| AU (1) | AU2007304837B2 (en) |
| BR (1) | BRPI0718137B1 (en) |
| CA (1) | CA2663164C (en) |
| DK (1) | DK2066817T3 (en) |
| ES (1) | ES2520023T3 (en) |
| IL (1) | IL197543A (en) |
| MX (1) | MX2009003193A (en) |
| WO (1) | WO2008040095A1 (en) |
| ZA (1) | ZA200901742B (en) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5665272B2 (en) | 2005-10-07 | 2015-02-04 | スピーデクス ピーティーワイ リミテッド | Multi-component nucleic acid enzymes and methods for their use |
| EP1987166A4 (en) * | 2006-02-03 | 2010-06-02 | Univ Columbia | Binary deoxyribozyme probes for nucleic acid analysis |
| KR20090098960A (en) | 2006-10-06 | 2009-09-18 | 존슨 앤드 존슨 리서치 피티와이 리미티드 | Molecular switches and methods for their use |
| AU2008235256B2 (en) * | 2007-04-05 | 2014-05-15 | Speedx Pty Ltd | Nucleic acid enzymes and complexes and methods for their use |
| US9051606B2 (en) | 2010-09-10 | 2015-06-09 | Qiagen Gaithersburg, Inc. | Methods and compositions for nucleic acid detection |
| BR112013012450B1 (en) | 2010-11-19 | 2020-10-13 | Speedx Pty Ltd | target detection methods |
| MX349801B (en) * | 2011-09-09 | 2017-08-14 | Speedx Pty Ltd | Nucleic acid enzyme substrates. |
| WO2013123220A1 (en) * | 2012-02-14 | 2013-08-22 | Cornell University | Method for relative quantification of nucleic acid sequence, expression, or copy changes, using combined nuclease, ligation, and polymerase reactions |
| CA2863808C (en) | 2012-02-20 | 2020-07-21 | Speedx Pty Ltd | Methods and oligonucleotides for amplifying and/or detecting nucleic acids |
| AU2013202354A1 (en) * | 2012-06-18 | 2014-01-16 | Speedx Pty Ltd | Target detection and signal amplification |
| US10316320B2 (en) | 2013-04-18 | 2019-06-11 | Bar Ilan University | Systems comprising non-immunogenic and nuclease resistant nucleic acid origami devices for molecular computation |
| CN105763200B (en) * | 2016-02-05 | 2018-10-16 | 大连大学 | 4-10 decoder design methods based on DNA chain displacement |
| CN105954957B (en) * | 2016-05-02 | 2018-10-23 | 福建医科大学 | NAND gate based on gold nano cluster solid-phase complex and its construction method |
| US11614403B2 (en) | 2017-08-10 | 2023-03-28 | Fox Biosystems Nv | Nucleic acid enzyme sensor |
| CA3108430A1 (en) * | 2018-08-09 | 2020-02-13 | Speedx Pty Ltd | Multiplex detection of nucleic acids |
| KR102239459B1 (en) * | 2019-09-16 | 2021-04-12 | 한국화학연구원 | Composition for temperature sensors including graphene oxide, DNAzyme and PNA and temperature sensing method using the same |
| CN112501260B (en) * | 2020-11-27 | 2021-06-29 | 广东省科学院生态环境与土壤研究所 | Bisphenol A detection method, fluorescence detection kit and application thereof |
| CN112630439A (en) * | 2020-12-11 | 2021-04-09 | 郑州轻工业大学 | Splitting aptamer sensor based on nanogold and preparation method and application thereof |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4000A (en) * | 1845-04-16 | Combined lock and latch | ||
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4965188A (en) * | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US5176995A (en) * | 1985-03-28 | 1993-01-05 | Hoffmann-La Roche Inc. | Detection of viruses by amplification and hybridization |
| US4800159A (en) * | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| MC2115A1 (en) | 1987-12-15 | 1991-07-05 | Gene Shears Pty Ltd | RIBOZYNES |
| US5424413A (en) | 1992-01-22 | 1995-06-13 | Gen-Probe Incorporated | Branched nucleic acid probes |
| ATE217347T1 (en) * | 1992-12-04 | 2002-05-15 | Univ Yale | DIAGNOSIS USING SIGNAL AMPLIFICATION BY A RIBOZYME |
| US5876924A (en) | 1994-06-22 | 1999-03-02 | Mount Sinai School Of Medicine | Nucleic acid amplification method hybridization signal amplification method (HSAM) |
| US5807718A (en) * | 1994-12-02 | 1998-09-15 | The Scripps Research Institute | Enzymatic DNA molecules |
| US7141665B1 (en) * | 1998-04-29 | 2006-11-28 | The Scripps Research Institute | Enzymatic DNA molecules |
| US5545729A (en) * | 1994-12-22 | 1996-08-13 | Hybridon, Inc. | Stabilized ribozyme analogs |
| MX9706501A (en) | 1995-02-27 | 1998-02-28 | Intelligene Ltd | Detection of biomolecules. |
| JP4203126B2 (en) | 1997-04-29 | 2008-12-24 | ザ スクリップス リサーチ インスティテュート | Enzymatic DNA molecule |
| IL138126A0 (en) * | 1998-03-05 | 2001-10-31 | Johnson & Johnson Res Pty Ltd | Zymogenic nucleic acid detection methods and related molecules and kits |
| EP1063296A1 (en) * | 1998-03-12 | 2000-12-27 | Taisho Pharmaceutical Co., Ltd | Nucleic acid enzyme showing allosteric rna-cleaving activity on target rna |
| DE19811618C1 (en) * | 1998-03-17 | 2000-08-31 | Andreas Jenne | DNA encoding ribozyme and an oligonucleotide substrate-containing composition and method for measuring transcription rates |
| ATE431852T1 (en) | 1998-03-27 | 2009-06-15 | Johnson & Johnson Res Pty Ltd | DIAGNOSTIC METHODS BASED ON CATALYTIC NUCLEIC ACIDS |
| DE19915141C2 (en) | 1999-03-26 | 2002-11-21 | Artus Ges Fuer Molekularbiolog | Detection of nucleic acid amplificates |
| JP2003525631A (en) * | 2000-03-06 | 2003-09-02 | リボザイム・ファーマシューティカルズ・インコーポレーテッド | Nucleic acid sensor molecule |
| JP3595843B2 (en) * | 2000-10-13 | 2004-12-02 | 独立行政法人産業技術総合研究所 | Nucleic acid enzymes that acquire cleavage activity against other specific target RNAs by recognizing RNA molecules |
| AU2002367785A1 (en) | 2001-11-05 | 2003-11-03 | Sirna Therapeutics, Inc | Allosteric nucleic acid sensor molecules |
| WO2005051174A2 (en) | 2003-11-21 | 2005-06-09 | The Trustees Of Columbia University In The City Of New York | Nucleic acid aptamer-based compositions and methods |
| US20070254282A1 (en) | 2004-01-29 | 2007-11-01 | Yissum Research And Development Company Of The Hebrew University Of Jerusalem | Catalytic Polynucleotide and Its Use for Determination of Analytes |
| US7553945B2 (en) * | 2005-08-03 | 2009-06-30 | Bowling Green State University | RNA complexes and methods of their production |
| JP5665272B2 (en) * | 2005-10-07 | 2015-02-04 | スピーデクス ピーティーワイ リミテッド | Multi-component nucleic acid enzymes and methods for their use |
| ZA200802937B (en) * | 2005-10-07 | 2009-09-30 | Johnson & Johnson Res Pty Ltd | Multicomponent nucleic acid enzymes and methods for their use |
| CN101365808B (en) * | 2005-12-07 | 2012-04-25 | 泰博特克药品有限公司 | Methods, plasmid vectors and primers for assessing HIV viralfitness |
| EP1987166A4 (en) * | 2006-02-03 | 2010-06-02 | Univ Columbia | Binary deoxyribozyme probes for nucleic acid analysis |
| KR20090098960A (en) | 2006-10-06 | 2009-09-18 | 존슨 앤드 존슨 리서치 피티와이 리미티드 | Molecular switches and methods for their use |
| AU2008235256B2 (en) | 2007-04-05 | 2014-05-15 | Speedx Pty Ltd | Nucleic acid enzymes and complexes and methods for their use |
| AU2008235527B2 (en) * | 2007-04-06 | 2014-02-20 | Speedx Pty Ltd | Respiratory syncytial virus (RSV) viral load detection assay |
| JP2010535528A (en) | 2007-08-13 | 2010-11-25 | ユニバーシティ オブ ストラスクライド | Nucleic acid sequence identification |
| WO2010017246A1 (en) | 2008-08-04 | 2010-02-11 | University Of Maryland | Probes and methods for detecting analytes |
-
2007
- 2007-10-05 KR KR1020097009384A patent/KR20090098960A/en not_active Application Discontinuation
- 2007-10-05 WO PCT/AU2007/001517 patent/WO2008040095A1/en active Application Filing
- 2007-10-05 JP JP2009530739A patent/JP5688507B2/en not_active Expired - Fee Related
- 2007-10-05 BR BRPI0718137A patent/BRPI0718137B1/en active IP Right Grant
- 2007-10-05 CA CA2663164A patent/CA2663164C/en active Active
- 2007-10-05 AU AU2007304837A patent/AU2007304837B2/en not_active Ceased
- 2007-10-05 ES ES07815323.6T patent/ES2520023T3/en active Active
- 2007-10-05 CN CN200780037345.2A patent/CN101600808B/en active Active
- 2007-10-05 MX MX2009003193A patent/MX2009003193A/en active IP Right Grant
- 2007-10-05 US US12/442,275 patent/US9127311B2/en not_active Expired - Fee Related
- 2007-10-05 EP EP07815323.6A patent/EP2066817B1/en active Active
- 2007-10-05 ZA ZA200901742A patent/ZA200901742B/en unknown
- 2007-10-05 DK DK07815323.6T patent/DK2066817T3/en active
-
2009
- 2009-03-11 IL IL197543A patent/IL197543A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EP2066817A4 (en) | 2011-02-09 |
| ES2520023T3 (en) | 2014-11-11 |
| CA2663164C (en) | 2016-07-12 |
| AU2007304837A1 (en) | 2008-04-10 |
| ZA200901742B (en) | 2010-06-30 |
| MX2009003193A (en) | 2009-08-13 |
| JP5688507B2 (en) | 2015-03-25 |
| EP2066817A1 (en) | 2009-06-10 |
| IL197543A (en) | 2016-10-31 |
| EP2066817B1 (en) | 2014-07-30 |
| JP2010505394A (en) | 2010-02-25 |
| CN101600808B (en) | 2014-07-09 |
| CA2663164A1 (en) | 2008-04-10 |
| KR20090098960A (en) | 2009-09-18 |
| WO2008040095A1 (en) | 2008-04-10 |
| IL197543A0 (en) | 2009-12-24 |
| US20100136536A1 (en) | 2010-06-03 |
| BRPI0718137B1 (en) | 2016-05-10 |
| AU2007304837B2 (en) | 2011-09-29 |
| US9127311B2 (en) | 2015-09-08 |
| CN101600808A (en) | 2009-12-09 |
| BRPI0718137A2 (en) | 2013-11-05 |
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