ZA200901742B - Moleculor switches and methods for their use - Google Patents
Moleculor switches and methods for their useInfo
- Publication number
- ZA200901742B ZA200901742B ZA200901742A ZA200901742A ZA200901742B ZA 200901742 B ZA200901742 B ZA 200901742B ZA 200901742 A ZA200901742 A ZA 200901742A ZA 200901742 A ZA200901742 A ZA 200901742A ZA 200901742 B ZA200901742 B ZA 200901742B
- Authority
- ZA
- South Africa
- Prior art keywords
- moleculor
- switches
- methods
- moleculor switches
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/30—Phosphoric diester hydrolysing, i.e. nuclease
- C12Q2521/337—Ribozyme
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/50—Other enzymatic activities
- C12Q2521/501—Ligase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/125—Sandwich assay format
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/10—Detection mode being characterised by the assay principle
- C12Q2565/101—Interaction between at least two labels
- C12Q2565/1015—Interaction between at least two labels labels being on the same oligonucleotide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82845106P | 2006-10-06 | 2006-10-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200901742B true ZA200901742B (en) | 2010-06-30 |
Family
ID=39268069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200901742A ZA200901742B (en) | 2006-10-06 | 2007-10-05 | Moleculor switches and methods for their use |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9127311B2 (xx) |
| EP (1) | EP2066817B1 (xx) |
| JP (1) | JP5688507B2 (xx) |
| KR (1) | KR20090098960A (xx) |
| CN (1) | CN101600808B (xx) |
| AU (1) | AU2007304837B2 (xx) |
| BR (1) | BRPI0718137B1 (xx) |
| CA (1) | CA2663164C (xx) |
| DK (1) | DK2066817T3 (xx) |
| ES (1) | ES2520023T3 (xx) |
| IL (1) | IL197543A (xx) |
| MX (1) | MX2009003193A (xx) |
| WO (1) | WO2008040095A1 (xx) |
| ZA (1) | ZA200901742B (xx) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1948822T3 (da) | 2005-10-07 | 2011-10-17 | Johnson & Johnson Res Pty Ltd | Multikomponent-nukleinsyreenzymer og fremgangsmåder til deres anvendelse |
| WO2008054834A2 (en) * | 2006-02-03 | 2008-05-08 | Columbia University | Binary deoxyribozyme probes for nucleic acid analysis |
| ES2520023T3 (es) | 2006-10-06 | 2014-11-11 | Speedx Pty Ltd | Interruptores moleculares y métodos para su uso |
| KR101583834B1 (ko) * | 2007-04-05 | 2016-01-19 | 존슨 앤드 존슨 리서치 피티와이 리미티드 | 핵산 효소 및 복합체 및 이의 사용 방법 |
| US9051606B2 (en) | 2010-09-10 | 2015-06-09 | Qiagen Gaithersburg, Inc. | Methods and compositions for nucleic acid detection |
| EP2640852B1 (en) | 2010-11-19 | 2018-08-22 | Speedx Pty Ltd | Signal amplification |
| BR112014005505B1 (pt) * | 2011-09-09 | 2021-01-12 | Speedx Pty Ltd. | substrato de polinucleotídeo isolado para uma enzima de ácido nucleico multi-componente (mnazima) ou dnazima, método para detectar a presença de pelo menos um alvo, kit e montagem |
| AU2013221480B2 (en) * | 2012-02-14 | 2018-08-23 | Cornell University | Method for relative quantification of nucleic acid sequence, expression, or copy changes, using combined nuclease, ligation, and polymerase reactions |
| NO2817421T3 (xx) * | 2012-02-20 | 2018-05-12 | ||
| AU2013202354A1 (en) * | 2012-06-18 | 2014-01-16 | Speedx Pty Ltd | Target detection and signal amplification |
| US10316320B2 (en) | 2013-04-18 | 2019-06-11 | Bar Ilan University | Systems comprising non-immunogenic and nuclease resistant nucleic acid origami devices for molecular computation |
| CN105763200B (zh) * | 2016-02-05 | 2018-10-16 | 大连大学 | 基于dna链置换的4-10译码器设计方法 |
| CN105954957B (zh) * | 2016-05-02 | 2018-10-23 | 福建医科大学 | 基于金纳米团簇固相复合物的nand逻辑门及其构建方法 |
| EP3665305A1 (en) | 2017-08-10 | 2020-06-17 | Katholieke Universiteit Leuven | Nucleic acid enzyme sensor |
| SG11201912883WA (en) | 2017-12-21 | 2020-01-30 | Speedx Pty Ltd | Nucleic acid ratio determination |
| CA3108430A1 (en) * | 2018-08-09 | 2020-02-13 | Speedx Pty Ltd | Multiplex detection of nucleic acids |
| KR102239459B1 (ko) * | 2019-09-16 | 2021-04-12 | 한국화학연구원 | 산화 그래핀, DNAzyme 및 PNA를 포함하는 온도 센서용 조성물 및 이를 이용한 온도 센싱 방법 |
| CN112501260B (zh) * | 2020-11-27 | 2021-06-29 | 广东省科学院生态环境与土壤研究所 | 一种双酚a的检测方法、荧光检测试剂盒及其应用 |
| CN112630439A (zh) * | 2020-12-11 | 2021-04-09 | 郑州轻工业大学 | 基于纳米金的分裂型适体传感器及其制备方法和应用 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4000A (en) * | 1845-04-16 | Combined lock and latch | ||
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5176995A (en) | 1985-03-28 | 1993-01-05 | Hoffmann-La Roche Inc. | Detection of viruses by amplification and hybridization |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| AR243935A1 (es) | 1987-12-15 | 1993-09-30 | Gene Shears Pty Ltd | Compuesto oligonucleotidico de aplicacion biologica en plantas y excluyendo su uso farmaceutico, metodo para prepararlo y composicion que lo comprende. |
| US5424413A (en) | 1992-01-22 | 1995-06-13 | Gen-Probe Incorporated | Branched nucleic acid probes |
| WO1994013833A1 (en) | 1992-12-04 | 1994-06-23 | Innovir Laboratories, Inc. | Ribozyme amplified diagnostics |
| US5876924A (en) | 1994-06-22 | 1999-03-02 | Mount Sinai School Of Medicine | Nucleic acid amplification method hybridization signal amplification method (HSAM) |
| US5807718A (en) | 1994-12-02 | 1998-09-15 | The Scripps Research Institute | Enzymatic DNA molecules |
| US7141665B1 (en) | 1998-04-29 | 2006-11-28 | The Scripps Research Institute | Enzymatic DNA molecules |
| US5545729A (en) * | 1994-12-22 | 1996-08-13 | Hybridon, Inc. | Stabilized ribozyme analogs |
| AU697317B2 (en) | 1995-02-27 | 1998-10-01 | Intelligene Ltd. | Detection of biomolecules |
| AU735522C (en) | 1997-04-29 | 2005-04-07 | Scripps Research Institute, The | Enzymatic dna molecules |
| CA2321948A1 (en) | 1998-03-05 | 1999-09-10 | Johnson & Johnson Research Pty. Limited | Zymogenic nucleic acid detection methods, and related molecules and kits |
| EP1063296A1 (en) * | 1998-03-12 | 2000-12-27 | Taisho Pharmaceutical Co., Ltd | Nucleic acid enzyme showing allosteric rna-cleaving activity on target rna |
| DE19811618C1 (de) | 1998-03-17 | 2000-08-31 | Andreas Jenne | Ribozym codierende DNA und ein Oligonucleotidsubstrat enthaltende Zusammensetzung und Verfahren zur Messung von Transkriptionsraten |
| ATE431852T1 (de) | 1998-03-27 | 2009-06-15 | Johnson & Johnson Res Pty Ltd | Diagnostische methoden basierend auf katalytischen nukleinsäuren |
| DE19915141C2 (de) | 1999-03-26 | 2002-11-21 | Artus Ges Fuer Molekularbiolog | Detektion von Nucleinsäure-Amplifikaten |
| WO2003089650A2 (en) | 2001-11-05 | 2003-10-30 | Sirna Therapeutics, Inc. | Allosteric nucleic acid sensor molecules |
| AU4345401A (en) | 2000-03-06 | 2001-09-17 | Ribozyme Pharmaceuticals, Inc. | Nucleic acid sensor molecules |
| JP3595843B2 (ja) * | 2000-10-13 | 2004-12-02 | 独立行政法人産業技術総合研究所 | Ｒｎａ分子を認識することにより他の特定の標的ｒｎａに対する切断活性を獲得する核酸酵素 |
| WO2005051174A2 (en) | 2003-11-21 | 2005-06-09 | The Trustees Of Columbia University In The City Of New York | Nucleic acid aptamer-based compositions and methods |
| WO2005073405A2 (en) | 2004-01-29 | 2005-08-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Catalytic polynucleotide and its use for determination of analytes |
| US7553945B2 (en) * | 2005-08-03 | 2009-06-30 | Bowling Green State University | RNA complexes and methods of their production |
| ES2370910T3 (es) * | 2005-10-07 | 2011-12-23 | Johnson & Johnson Research Pty Limited | Enzimas de ácido nucleico multicomponentes y procedimientos para su uso. |
| DK1948822T3 (da) | 2005-10-07 | 2011-10-17 | Johnson & Johnson Res Pty Ltd | Multikomponent-nukleinsyreenzymer og fremgangsmåder til deres anvendelse |
| US8673551B2 (en) * | 2005-12-07 | 2014-03-18 | Speedx Pty Ltd. | Methods, plasmid vectors and primers for assessing HIV viral fitness |
| WO2008054834A2 (en) | 2006-02-03 | 2008-05-08 | Columbia University | Binary deoxyribozyme probes for nucleic acid analysis |
| ES2520023T3 (es) | 2006-10-06 | 2014-11-11 | Speedx Pty Ltd | Interruptores moleculares y métodos para su uso |
| KR101583834B1 (ko) | 2007-04-05 | 2016-01-19 | 존슨 앤드 존슨 리서치 피티와이 리미티드 | 핵산 효소 및 복합체 및 이의 사용 방법 |
| WO2008122598A2 (en) | 2007-04-06 | 2008-10-16 | Virco Bvba | Respiratory syncytial virus (rsv) viral load detection assay |
| WO2009022125A1 (en) | 2007-08-13 | 2009-02-19 | University Of Strathclyde | Identification of nucleic acid sequences |
| US20110207132A1 (en) | 2008-08-04 | 2011-08-25 | University Of Maryland | Probes and methods for detecting analytes |
-
2007
- 2007-10-05 ES ES07815323.6T patent/ES2520023T3/es active Active
- 2007-10-05 DK DK07815323.6T patent/DK2066817T3/da active
- 2007-10-05 US US12/442,275 patent/US9127311B2/en not_active Expired - Fee Related
- 2007-10-05 CA CA2663164A patent/CA2663164C/en active Active
- 2007-10-05 CN CN200780037345.2A patent/CN101600808B/zh not_active Expired - Fee Related
- 2007-10-05 WO PCT/AU2007/001517 patent/WO2008040095A1/en active Application Filing
- 2007-10-05 BR BRPI0718137A patent/BRPI0718137B1/pt not_active IP Right Cessation
- 2007-10-05 MX MX2009003193A patent/MX2009003193A/es active IP Right Grant
- 2007-10-05 KR KR1020097009384A patent/KR20090098960A/ko not_active Application Discontinuation
- 2007-10-05 ZA ZA200901742A patent/ZA200901742B/xx unknown
- 2007-10-05 JP JP2009530739A patent/JP5688507B2/ja not_active Expired - Fee Related
- 2007-10-05 AU AU2007304837A patent/AU2007304837B2/en not_active Ceased
- 2007-10-05 EP EP07815323.6A patent/EP2066817B1/en active Active
-
2009
- 2009-03-11 IL IL197543A patent/IL197543A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CA2663164A1 (en) | 2008-04-10 |
| JP5688507B2 (ja) | 2015-03-25 |
| IL197543A0 (en) | 2009-12-24 |
| BRPI0718137A2 (pt) | 2013-11-05 |
| US9127311B2 (en) | 2015-09-08 |
| EP2066817A4 (en) | 2011-02-09 |
| ES2520023T3 (es) | 2014-11-11 |
| WO2008040095A1 (en) | 2008-04-10 |
| EP2066817A1 (en) | 2009-06-10 |
| BRPI0718137B1 (pt) | 2016-05-10 |
| DK2066817T3 (da) | 2014-10-13 |
| IL197543A (en) | 2016-10-31 |
| EP2066817B1 (en) | 2014-07-30 |
| AU2007304837B2 (en) | 2011-09-29 |
| CN101600808B (zh) | 2014-07-09 |
| AU2007304837A1 (en) | 2008-04-10 |
| MX2009003193A (es) | 2009-08-13 |
| CN101600808A (zh) | 2009-12-09 |
| CA2663164C (en) | 2016-07-12 |
| KR20090098960A (ko) | 2009-09-18 |
| US20100136536A1 (en) | 2010-06-03 |
| JP2010505394A (ja) | 2010-02-25 |
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