CY1123505T1 - Καινοτομα πεπτιδια και συνδυασμος πεπτιδιων για χρηση στην ανοσοθεραπεια εναντι του επιθηλιακου καρκινου των ωοθηκων και αλλων καρκινων - Google Patents

Καινοτομα πεπτιδια και συνδυασμος πεπτιδιων για χρηση στην ανοσοθεραπεια εναντι του επιθηλιακου καρκινου των ωοθηκων και αλλων καρκινων

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Publication number
CY1123505T1
CY1123505T1 CY20201100848T CY201100848T CY1123505T1 CY 1123505 T1 CY1123505 T1 CY 1123505T1 CY 20201100848 T CY20201100848 T CY 20201100848T CY 201100848 T CY201100848 T CY 201100848T CY 1123505 T1 CY1123505 T1 CY 1123505T1
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CY
Cyprus
Prior art keywords
cancer
peptides
present
epithelial ovarian
novel peptides
Prior art date
Application number
CY20201100848T
Other languages
English (en)
Inventor
Heiko Schuster
Janet PEPER
Philipp Wagner
Hans-Georg Rammensee
Original Assignee
Immatics Biotechnologies Gmbh
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Filing date
Publication date
Application filed by Immatics Biotechnologies Gmbh filed Critical Immatics Biotechnologies Gmbh
Publication of CY1123505T1 publication Critical patent/CY1123505T1/el

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Abstract

Η παρούσα εφεύρεση σχετίζεται με ένα πεπτίδιο, πρωτεΐνες, νουκλεϊκά οξέα και κύτταρα για χρήση σε ανοσοθεραπευτικές μεθόδους. Συγκεκριμένα, η παρούσα εφεύρεση σχετίζεται με την ανοσοθεραπεία του καρκίνου. Η παρούσα εφεύρεση σχετίζεται επιπλέον με όγκο-σχετιζόμενους πεπτιδικούς επιτόπους Τ-κυττάρων, μεμονωμένους ή σε συνδυασμό με άλλα ογκο-σχετιζόμενα πεπτίδια, τα οποία μπορούν, για παράδειγμα, να λειτουργούν ως ενεργά φαρμακευτικά συστατικά συνθέσεων εμβολίων που διεγείρουν αντικαρκινικές ανοσοαπαντήσεις ή για τη διέγερση Τ-κυττάρων ex vivo και τη μεταφορά τους σε ασθενείς. Πεπτίδια προσδεδεμένα σε μόρια του μείζονος συμπλέγματος ιστοσυμβατότητας (major histocompatibility complex, MHC) ή παρόμοια πεπτίδια, μπορούν επίσης να αποτελέσουν στόχους αντισωμάτων, διαλυτών υποδοχέων Τ-κυττάρων και άλλων μορίων πρόσδεσης.
CY20201100848T 2015-07-15 2020-09-08 Καινοτομα πεπτιδια και συνδυασμος πεπτιδιων για χρηση στην ανοσοθεραπεια εναντι του επιθηλιακου καρκινου των ωοθηκων και αλλων καρκινων CY1123505T1 (el)

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US20200155603A1 (en) 2020-05-21
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WO2017009400A1 (en) 2017-01-19
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IL256697A (en) 2018-03-29
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