CY1120521T1 - Παρασκευασμα προμειγματος δεξμεδετομιδινης - Google Patents
Παρασκευασμα προμειγματος δεξμεδετομιδινηςInfo
- Publication number
- CY1120521T1 CY1120521T1 CY20181100462T CY181100462T CY1120521T1 CY 1120521 T1 CY1120521 T1 CY 1120521T1 CY 20181100462 T CY20181100462 T CY 20181100462T CY 181100462 T CY181100462 T CY 181100462T CY 1120521 T1 CY1120521 T1 CY 1120521T1
- Authority
- CY
- Cyprus
- Prior art keywords
- temxedetomidine
- extract
- preparation
- composition
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0023—Heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
Φαρμακευτικές συνθέσεις περιέχουν δεξμεδετομιδίνη ή ένα φαρμακευτικά αποδεκτό άλας αυτής, όπου η σύνθεση παρασκευάζεται ως ένα υγρό για παρεντερική χορήγηση σε ένα υποκείμενο και όπου η σύνθεση είναι τοποθετημένη εντός ενός σφραγισμένου περιέκτη ως ένα πρόμειγμα. Οι φαρμακευτικές συνθέσεις μπορούν να χρησιμοποιούνται στην περιεγχειρητική φροντίδα ενός ασθενούς ή για καταστολή.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/343,672 US8242158B1 (en) | 2012-01-04 | 2012-01-04 | Dexmedetomidine premix formulation |
PCT/US2012/042940 WO2013103378A1 (en) | 2012-01-04 | 2012-06-18 | Dexmedetomidine premix formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1120521T1 true CY1120521T1 (el) | 2019-07-10 |
Family
ID=46613447
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20181100462T CY1120521T1 (el) | 2012-01-04 | 2018-05-03 | Παρασκευασμα προμειγματος δεξμεδετομιδινης |
Country Status (35)
Country | Link |
---|---|
US (10) | US8242158B1 (el) |
EP (2) | EP3345599A1 (el) |
JP (4) | JP5892177B2 (el) |
KR (1) | KR101632103B1 (el) |
CN (2) | CN103281902A (el) |
AR (2) | AR089673A1 (el) |
AU (1) | AU2013201069B1 (el) |
BR (1) | BR112013008005A8 (el) |
CA (1) | CA2806706C (el) |
CL (1) | CL2013000815A1 (el) |
CO (1) | CO6680698A2 (el) |
CY (1) | CY1120521T1 (el) |
DK (1) | DK2648520T3 (el) |
EC (1) | ECSP13012569A (el) |
ES (1) | ES2671749T3 (el) |
GT (1) | GT201300055A (el) |
HK (1) | HK1249429A1 (el) |
HR (1) | HRP20180838T1 (el) |
HU (1) | HUE038128T2 (el) |
IL (1) | IL224867B (el) |
LT (1) | LT2648520T (el) |
MX (1) | MX2013003629A (el) |
MY (2) | MY188598A (el) |
PE (2) | PE20160681A1 (el) |
PL (1) | PL2648520T3 (el) |
PT (1) | PT2648520T (el) |
RS (1) | RS57346B1 (el) |
SA (2) | SA115360458B1 (el) |
SG (1) | SG191706A1 (el) |
SI (1) | SI2648520T1 (el) |
TR (1) | TR201809123T4 (el) |
TW (2) | TWI574688B (el) |
UY (1) | UY34562A (el) |
WO (1) | WO2013103378A1 (el) |
ZA (1) | ZA201301649B (el) |
Families Citing this family (33)
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US20130096170A1 (en) | 2011-10-14 | 2013-04-18 | Hospira, Inc. | Methods of treating pediatric patients using dexmedetomidine |
US8242158B1 (en) * | 2012-01-04 | 2012-08-14 | Hospira, Inc. | Dexmedetomidine premix formulation |
TWI629066B (zh) | 2013-10-07 | 2018-07-11 | 帝國製藥美國股份有限公司 | 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物 |
BR112016006848A2 (pt) * | 2013-10-07 | 2017-08-01 | Teikoku Pharma Usa Inc | métodos e composições para distribuição transdérmica de uma quantidade não sedativa de dexmedetomidina |
CA2924231C (en) | 2013-10-07 | 2018-04-03 | Teikoku Pharma Usa, Inc. | Dexmedetomidine transdermal delivery devices and methods for using the same |
US20150098983A1 (en) * | 2013-10-07 | 2015-04-09 | Teikoku Pharma Usa, Inc. | Methods and Compositions for Treating Withdrawal Syndromes Using Non-Sedative Dexmedetomidine Transdermal Compositions |
MX2016007902A (es) * | 2013-12-18 | 2016-10-28 | Gnt Llc | Composiciones y metodos para el tratamiento del glaucoma. |
FI127534B (en) * | 2014-11-10 | 2018-08-31 | Vetcare Oy | Substituted benzoefuroquinolizine and ɑ2-adrenergic agonist comprising compositions |
CN106038538A (zh) * | 2015-04-17 | 2016-10-26 | 江苏恒瑞医药股份有限公司 | 一种右美托咪定的预混合制剂 |
CN105168122B (zh) * | 2015-09-24 | 2018-11-27 | 辰欣药业股份有限公司 | 一种盐酸右美托咪定注射液及其制备工艺 |
US20170128421A1 (en) * | 2015-11-11 | 2017-05-11 | Siva Prasad Reddy Sura | Premix formulation for parenteral use and packaging thereof |
US10632043B2 (en) * | 2015-11-11 | 2020-04-28 | Aurobindo Pharma Ltd | Premix formulation for parenteral use and packaging thereof |
US9717796B1 (en) * | 2016-04-20 | 2017-08-01 | Slypharma, Llc | Heat sterilizeable, premixed, ready to use dexmedetomidine solution packaged in a flexible plastic container |
CN107412152B (zh) * | 2016-05-24 | 2020-12-04 | 海南合瑞制药股份有限公司 | 一种盐酸右美托咪定注射液组合物 |
EP3560495B1 (en) * | 2016-12-26 | 2021-07-28 | Hisamitsu Pharmaceutical Co., Inc. | Microneedle device |
CN110337290A (zh) | 2016-12-31 | 2019-10-15 | 比奥克斯塞尔医疗股份有限公司 | 舌下右旋美托咪啶用于治疗激越的用途 |
CN107028880A (zh) * | 2017-06-09 | 2017-08-11 | 安徽赛诺制药有限公司 | 一种盐酸右美托咪定注射液的生产工艺 |
US20190262314A1 (en) * | 2018-02-26 | 2019-08-29 | Slayback Pharma Llc | Ready-to-use dexmedetomidine compositions |
CN108956809B (zh) * | 2018-06-04 | 2021-03-23 | 四川科伦药物研究院有限公司 | 一种检测1-(1-氯乙基)-2,3-二甲苯有关物质的方法 |
WO2020006119A1 (en) | 2018-06-27 | 2020-01-02 | Bioxcel Therapeutics, Inc. | Methods for treating agitation using dexmedetomidine hydrochloride |
CN114983979A (zh) | 2018-06-27 | 2022-09-02 | 比奥克斯塞尔医疗股份有限公司 | 含右美托咪定的膜制剂及其制造方法 |
CN108872431B (zh) * | 2018-07-09 | 2021-03-23 | 成都倍特药业股份有限公司 | 一种检测4-(1-(2,5-二甲基苯基)乙基)-1h-咪唑或/和其盐酸盐的方法 |
CN109081811A (zh) * | 2018-09-19 | 2018-12-25 | 南京正大天晴制药有限公司 | 盐酸右美托咪定的有关物质及其制备方法 |
JP2019048091A (ja) * | 2018-10-23 | 2019-03-28 | ニプロ株式会社 | デクスメデトミジン注射液を充填したプレフィルドシリンジ |
US11160791B2 (en) | 2018-11-01 | 2021-11-02 | Medefil, Inc. | Dexmedetomidine injection premix formulation in ready to use (RTU) bags |
CN111481506B (zh) * | 2019-01-25 | 2023-01-24 | 江苏恒瑞医药股份有限公司 | 一种包含经鼻给药的右美托咪定组合物的药物制品 |
CN116474219A (zh) * | 2019-06-28 | 2023-07-25 | 四川普锐特药业有限公司 | 保持给药均一度的药物流体分配器及右美托咪定鼻喷器 |
BR112022000992A2 (pt) | 2019-07-19 | 2022-06-14 | Arx Llc | Regimes de tratamento de dexmedetomidina não sedantes |
CN116615243A (zh) * | 2020-10-08 | 2023-08-18 | 比奥克斯塞尔医疗股份有限公司 | 使用右美托咪啶盐酸盐治疗躁郁症和精神病 |
EP4085891A1 (en) | 2021-05-05 | 2022-11-09 | B. Braun Melsungen AG | Dexmedetomidine-solution in a low-density polyethylene container |
CN113041242A (zh) * | 2021-05-18 | 2021-06-29 | 上海交通大学医学院附属仁济医院 | 右美托咪定在促进肝脏再生中的应用 |
CN113116815A (zh) * | 2021-06-07 | 2021-07-16 | 辰欣药业股份有限公司 | 一种盐酸右美托咪定注射液的制备方法 |
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2012
- 2012-01-04 US US13/343,672 patent/US8242158B1/en active Active
- 2012-06-18 CN CN2012800037344A patent/CN103281902A/zh active Pending
- 2012-06-18 KR KR1020137007434A patent/KR101632103B1/ko active IP Right Grant
- 2012-06-18 CA CA2806706A patent/CA2806706C/en active Active
- 2012-06-18 EP EP18157214.0A patent/EP3345599A1/en not_active Withdrawn
- 2012-06-18 MY MYPI2017000279A patent/MY188598A/en unknown
- 2012-06-18 BR BR112013008005A patent/BR112013008005A8/pt not_active Application Discontinuation
- 2012-06-18 HU HUE12823234A patent/HUE038128T2/hu unknown
- 2012-06-18 RS RS20180628A patent/RS57346B1/sr unknown
- 2012-06-18 JP JP2013552744A patent/JP5892177B2/ja active Active
- 2012-06-18 CN CN201710644232.4A patent/CN107802624A/zh active Pending
- 2012-06-18 PE PE2016000713A patent/PE20160681A1/es unknown
- 2012-06-18 PL PL12823234T patent/PL2648520T3/pl unknown
- 2012-06-18 PE PE2013000622A patent/PE20131166A1/es not_active Application Discontinuation
- 2012-06-18 ES ES12823234.5T patent/ES2671749T3/es active Active
- 2012-06-18 TR TR2018/09123T patent/TR201809123T4/tr unknown
- 2012-06-18 EP EP12823234.5A patent/EP2648520B1/en not_active Revoked
- 2012-06-18 PT PT128232345T patent/PT2648520T/pt unknown
- 2012-06-18 MX MX2013003629A patent/MX2013003629A/es unknown
- 2012-06-18 LT LTEP12823234.5T patent/LT2648520T/lt unknown
- 2012-06-18 WO PCT/US2012/042940 patent/WO2013103378A1/en active Application Filing
- 2012-06-18 AU AU2013201069A patent/AU2013201069B1/en active Active
- 2012-06-18 SI SI201231312T patent/SI2648520T1/en unknown
- 2012-06-18 DK DK12823234.5T patent/DK2648520T3/en active
- 2012-06-18 MY MYPI2013000733A patent/MY161022A/en unknown
- 2012-06-18 SG SG2013015441A patent/SG191706A1/en unknown
- 2012-07-03 US US13/541,524 patent/US8338470B1/en active Active
- 2012-11-15 US US13/678,148 patent/US8455527B1/en active Active
- 2012-11-15 US US13/678,260 patent/US8436033B1/en active Active
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2013
- 2013-01-04 TW TW102100340A patent/TWI574688B/zh active
- 2013-01-04 TW TW105101909A patent/TWI593409B/zh active
- 2013-01-04 UY UY0001034562A patent/UY34562A/es not_active Application Discontinuation
- 2013-01-04 AR ARP130100046A patent/AR089673A1/es not_active Application Discontinuation
- 2013-01-05 SA SA115360458A patent/SA115360458B1/ar unknown
- 2013-01-05 SA SA113340176A patent/SA113340176B1/ar unknown
- 2013-02-21 IL IL224867A patent/IL224867B/en active IP Right Grant
- 2013-02-27 GT GT201300055A patent/GT201300055A/es unknown
- 2013-03-04 ZA ZA2013/01649A patent/ZA201301649B/en unknown
- 2013-03-06 CO CO13045125A patent/CO6680698A2/es unknown
- 2013-03-22 CL CL2013000815A patent/CL2013000815A1/es unknown
- 2013-04-19 EC ECSP13012569 patent/ECSP13012569A/es unknown
- 2013-04-22 US US13/867,861 patent/US8648106B2/en active Active
- 2013-11-12 HK HK18109069.7A patent/HK1249429A1/zh unknown
- 2013-12-27 JP JP2013273409A patent/JP5990832B2/ja active Active
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2014
- 2014-01-24 JP JP2014011233A patent/JP5927680B2/ja active Active
- 2014-02-10 US US14/177,008 patent/US9320712B2/en active Active
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2015
- 2015-02-06 JP JP2015022203A patent/JP2015110639A/ja not_active Withdrawn
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2016
- 2016-03-02 US US15/058,602 patent/US9616049B2/en active Active
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2017
- 2017-02-28 US US15/444,932 patent/US10016396B2/en active Active
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2018
- 2018-05-03 CY CY20181100462T patent/CY1120521T1/el unknown
- 2018-05-25 HR HRP20180838TT patent/HRP20180838T1/hr unknown
- 2018-06-08 US US16/003,894 patent/US20180289674A1/en not_active Abandoned
- 2018-06-08 US US16/003,850 patent/US20180289673A1/en not_active Abandoned
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2019
- 2019-11-06 AR ARP190103245A patent/AR117001A2/es unknown
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