RS57346B1 - Premiks formulacija deksmedetomidina - Google Patents
Premiks formulacija deksmedetomidinaInfo
- Publication number
- RS57346B1 RS57346B1 RS20180628A RSP20180628A RS57346B1 RS 57346 B1 RS57346 B1 RS 57346B1 RS 20180628 A RS20180628 A RS 20180628A RS P20180628 A RSP20180628 A RS P20180628A RS 57346 B1 RS57346 B1 RS 57346B1
- Authority
- RS
- Serbia
- Prior art keywords
- premix formulation
- dexmedetomidine
- dexmedetomidine premix
- formulation
- premix
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0023—Heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Anesthesiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/343,672 US8242158B1 (en) | 2012-01-04 | 2012-01-04 | Dexmedetomidine premix formulation |
EP12823234.5A EP2648520B1 (en) | 2012-01-04 | 2012-06-18 | Dexmedetomidine premix formulation |
PCT/US2012/042940 WO2013103378A1 (en) | 2012-01-04 | 2012-06-18 | Dexmedetomidine premix formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
RS57346B1 true RS57346B1 (sr) | 2018-08-31 |
Family
ID=46613447
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20180628A RS57346B1 (sr) | 2012-01-04 | 2012-06-18 | Premiks formulacija deksmedetomidina |
Country Status (35)
Country | Link |
---|---|
US (10) | US8242158B1 (sr) |
EP (2) | EP3345599A1 (sr) |
JP (4) | JP5892177B2 (sr) |
KR (1) | KR101632103B1 (sr) |
CN (2) | CN103281902A (sr) |
AR (2) | AR089673A1 (sr) |
AU (1) | AU2013201069B1 (sr) |
BR (1) | BR112013008005A8 (sr) |
CA (1) | CA2806706C (sr) |
CL (1) | CL2013000815A1 (sr) |
CO (1) | CO6680698A2 (sr) |
CY (1) | CY1120521T1 (sr) |
DK (1) | DK2648520T3 (sr) |
EC (1) | ECSP13012569A (sr) |
ES (1) | ES2671749T3 (sr) |
GT (1) | GT201300055A (sr) |
HK (1) | HK1249429A1 (sr) |
HR (1) | HRP20180838T1 (sr) |
HU (1) | HUE038128T2 (sr) |
IL (1) | IL224867B (sr) |
LT (1) | LT2648520T (sr) |
MX (1) | MX2013003629A (sr) |
MY (2) | MY188598A (sr) |
PE (2) | PE20131166A1 (sr) |
PL (1) | PL2648520T3 (sr) |
PT (1) | PT2648520T (sr) |
RS (1) | RS57346B1 (sr) |
SA (2) | SA115360458B1 (sr) |
SG (1) | SG191706A1 (sr) |
SI (1) | SI2648520T1 (sr) |
TR (1) | TR201809123T4 (sr) |
TW (2) | TWI593409B (sr) |
UY (1) | UY34562A (sr) |
WO (1) | WO2013103378A1 (sr) |
ZA (1) | ZA201301649B (sr) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20130096170A1 (en) | 2011-10-14 | 2013-04-18 | Hospira, Inc. | Methods of treating pediatric patients using dexmedetomidine |
US8242158B1 (en) * | 2012-01-04 | 2012-08-14 | Hospira, Inc. | Dexmedetomidine premix formulation |
TWI624278B (zh) * | 2013-10-07 | 2018-05-21 | 帝國製藥美國股份有限公司 | 使用非鎮靜性右美托咪啶經皮組成物用於治療戒斷症候群的方法及組成物 |
TWI629066B (zh) | 2013-10-07 | 2018-07-11 | 帝國製藥美國股份有限公司 | 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物 |
TWI629067B (zh) | 2013-10-07 | 2018-07-11 | 美商帝國製藥美國股份有限公司 | 用於經皮輸送非鎮靜量右美托咪啶之方法及組成物 |
CN110585173A (zh) | 2013-10-07 | 2019-12-20 | 帝国制药美国公司 | 右旋美托咪啶经皮递送装置及其使用方法 |
MX2016007902A (es) * | 2013-12-18 | 2016-10-28 | Gnt Llc | Composiciones y metodos para el tratamiento del glaucoma. |
FI127534B (en) * | 2014-11-10 | 2018-08-31 | Vetcare Oy | Substituted benzoefuroquinolizine and ɑ2-adrenergic agonist comprising compositions |
CN106038538A (zh) * | 2015-04-17 | 2016-10-26 | 江苏恒瑞医药股份有限公司 | 一种右美托咪定的预混合制剂 |
CN105168122B (zh) * | 2015-09-24 | 2018-11-27 | 辰欣药业股份有限公司 | 一种盐酸右美托咪定注射液及其制备工艺 |
US20170128421A1 (en) * | 2015-11-11 | 2017-05-11 | Siva Prasad Reddy Sura | Premix formulation for parenteral use and packaging thereof |
US10632043B2 (en) * | 2015-11-11 | 2020-04-28 | Aurobindo Pharma Ltd | Premix formulation for parenteral use and packaging thereof |
US9717796B1 (en) * | 2016-04-20 | 2017-08-01 | Slypharma, Llc | Heat sterilizeable, premixed, ready to use dexmedetomidine solution packaged in a flexible plastic container |
CN107412152B (zh) * | 2016-05-24 | 2020-12-04 | 海南合瑞制药股份有限公司 | 一种盐酸右美托咪定注射液组合物 |
EP3560495B1 (en) * | 2016-12-26 | 2021-07-28 | Hisamitsu Pharmaceutical Co., Inc. | Microneedle device |
DK3562486T3 (da) | 2016-12-31 | 2024-06-10 | Bioxcel Therapeutics Inc | Anvendelse af sublingual dexmedetomidin til behandling af agitation |
CN107028880A (zh) * | 2017-06-09 | 2017-08-11 | 安徽赛诺制药有限公司 | 一种盐酸右美托咪定注射液的生产工艺 |
WO2019164765A1 (en) * | 2018-02-26 | 2019-08-29 | Slayback Pharma Llc | Ready-to-use dexmedetomidine compositions |
CN108956809B (zh) * | 2018-06-04 | 2021-03-23 | 四川科伦药物研究院有限公司 | 一种检测1-(1-氯乙基)-2,3-二甲苯有关物质的方法 |
WO2020006119A1 (en) | 2018-06-27 | 2020-01-02 | Bioxcel Therapeutics, Inc. | Methods for treating agitation using dexmedetomidine hydrochloride |
JP7488201B2 (ja) | 2018-06-27 | 2024-05-21 | バイオエクセル セラピューティクス,インコーポレイテッド | デクスメデトミジンを含むフィルム製剤、及びその作製方法 |
CN108872431B (zh) * | 2018-07-09 | 2021-03-23 | 成都倍特药业股份有限公司 | 一种检测4-(1-(2,5-二甲基苯基)乙基)-1h-咪唑或/和其盐酸盐的方法 |
CN109081811A (zh) * | 2018-09-19 | 2018-12-25 | 南京正大天晴制药有限公司 | 盐酸右美托咪定的有关物质及其制备方法 |
JP2019048091A (ja) * | 2018-10-23 | 2019-03-28 | ニプロ株式会社 | デクスメデトミジン注射液を充填したプレフィルドシリンジ |
US11160791B2 (en) | 2018-11-01 | 2021-11-02 | Medefil, Inc. | Dexmedetomidine injection premix formulation in ready to use (RTU) bags |
CN111481506B (zh) * | 2019-01-25 | 2023-01-24 | 江苏恒瑞医药股份有限公司 | 一种包含经鼻给药的右美托咪定组合物的药物制品 |
CN116474219A (zh) * | 2019-06-28 | 2023-07-25 | 四川普锐特药业有限公司 | 保持给药均一度的药物流体分配器及右美托咪定鼻喷器 |
JP2022540706A (ja) | 2019-07-19 | 2022-09-16 | バイオエクセル セラピューティクス,インコーポレイテッド | 鎮静作用のないデクスメデトミジン治療レジメン |
AU2021356687A1 (en) * | 2020-10-08 | 2023-06-15 | Bioxcel Therapeutics, Inc. | Treatment of bipolar disorders and psychosis using dexmedetomidine hydrochloride |
EP4085891A1 (en) | 2021-05-05 | 2022-11-09 | B. Braun Melsungen AG | Dexmedetomidine-solution in a low-density polyethylene container |
CN113041242A (zh) * | 2021-05-18 | 2021-06-29 | 上海交通大学医学院附属仁济医院 | 右美托咪定在促进肝脏再生中的应用 |
CN113116815A (zh) * | 2021-06-07 | 2021-07-16 | 辰欣药业股份有限公司 | 一种盐酸右美托咪定注射液的制备方法 |
US11806334B1 (en) | 2023-01-12 | 2023-11-07 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
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-
2012
- 2012-01-04 US US13/343,672 patent/US8242158B1/en active Active
- 2012-06-18 PL PL12823234T patent/PL2648520T3/pl unknown
- 2012-06-18 CN CN2012800037344A patent/CN103281902A/zh active Pending
- 2012-06-18 TR TR2018/09123T patent/TR201809123T4/tr unknown
- 2012-06-18 CN CN201710644232.4A patent/CN107802624A/zh active Pending
- 2012-06-18 RS RS20180628A patent/RS57346B1/sr unknown
- 2012-06-18 KR KR1020137007434A patent/KR101632103B1/ko active IP Right Grant
- 2012-06-18 ES ES12823234.5T patent/ES2671749T3/es active Active
- 2012-06-18 DK DK12823234.5T patent/DK2648520T3/en active
- 2012-06-18 MX MX2013003629A patent/MX2013003629A/es unknown
- 2012-06-18 CA CA2806706A patent/CA2806706C/en active Active
- 2012-06-18 PT PT128232345T patent/PT2648520T/pt unknown
- 2012-06-18 JP JP2013552744A patent/JP5892177B2/ja active Active
- 2012-06-18 WO PCT/US2012/042940 patent/WO2013103378A1/en active Application Filing
- 2012-06-18 BR BR112013008005A patent/BR112013008005A8/pt not_active Application Discontinuation
- 2012-06-18 AU AU2013201069A patent/AU2013201069B1/en active Active
- 2012-06-18 MY MYPI2017000279A patent/MY188598A/en unknown
- 2012-06-18 EP EP18157214.0A patent/EP3345599A1/en not_active Withdrawn
- 2012-06-18 MY MYPI2013000733A patent/MY161022A/en unknown
- 2012-06-18 SG SG2013015441A patent/SG191706A1/en unknown
- 2012-06-18 PE PE2013000622A patent/PE20131166A1/es not_active Application Discontinuation
- 2012-06-18 HU HUE12823234A patent/HUE038128T2/hu unknown
- 2012-06-18 PE PE2016000713A patent/PE20160681A1/es unknown
- 2012-06-18 SI SI201231312T patent/SI2648520T1/en unknown
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