CY1118167T1 - Πρωτογενη και εγγυς ηπατικα βλαστοκυτταρα - Google Patents
Πρωτογενη και εγγυς ηπατικα βλαστοκυτταραInfo
- Publication number
- CY1118167T1 CY1118167T1 CY20161100363T CY161100363T CY1118167T1 CY 1118167 T1 CY1118167 T1 CY 1118167T1 CY 20161100363 T CY20161100363 T CY 20161100363T CY 161100363 T CY161100363 T CY 161100363T CY 1118167 T1 CY1118167 T1 CY 1118167T1
- Authority
- CY
- Cyprus
- Prior art keywords
- liver
- stem cells
- human
- primary
- cells
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/067—Hepatocytes
- C12N5/0672—Stem cells; Progenitor cells; Precursor cells; Oval cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/36—Lipids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70525—ICAM molecules, e.g. CD50, CD54, CD102
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
Abstract
Τα ηπατικά προγονικά κύτταρα περιλαμβάνουν δύο πληθυσμούς ανθρώπινων ηπατικών βλαστοκυττάρων, τα πρωτογενή και τα εγγύς ηπατικά βλαστοκύτταρα, και δύο πληθυσμούς δεσμευμένων προγονικών κυττάρων, έναν για τα χολικά κύτταρα και έναν για τα ηπατοκύτταρα. Τα ανθρώπινα πρωτογενή ηπατικά βλαστοκύτταρα είναι ένα πολύ μικρό τμήμα του ηπατικού κυτταρικού πληθυσμού και οδηγούν σε εγγύς ηπατικά βλαστοκύτταρα που απαρτίζουν ένα πολύ μεγαλύτερο τμήμα του ήπατος. Τα ανθρώπινα εγγύς ηπατικά βλαστοκύτταρα οδηγούν σε χολικά και ηπατοκυτταρικά δεσμευμένα προγονικά κύτταρα. Τα πρωτογενή και τα εγγύς βλαστοκύτταρα είναι τα πρωτογενή βλαστοκύτταρα για το ανθρώπινο ήπαρ. Τα ανθρώπινα πρωτογενή ηπατικά βλαστοκύτταρα μπορούν να απομονωθούν με ανοσοδιαλογή από ανθρώπινα ήπατα ή καλλιέργεια ανθρώπινων ηπατικών κυττάρων υπό συνθήκες που επιλέγονται για ένα ανθρώπινο πρωτογενές ηπατικό βλαστοκύτταρο. Τα εγγύς ηπατικά βλαστοκύτταρα μπορούν να απομονωθούν με ανοσοδιαλογή ή με την καλλιέργεια ανθρώπινων ηπατικών κυττάρων υπό συνθήκες που περιλαμβάνουν έναν αναπτυξιακό παράγοντα. Τα εγγύς ηπατικά βλαστοκύτταρα μπορούν επίσης να απομονωθούν με την καλλιέργεια αποικιών που περιλαμβάνουν ένα πρωτογενές ηπατικό βλαστοκύτταρο υπό συνθήκες οι οποίες περιλαμβάνουν έναν αναπτυξιακό παράγοντα. Οι συνθέσεις που προκύπτουν μπορούν να χρησιμοποιηθούν για τη θεραπευτική αντιμετώπιση ηπατικών διαταραχών και για την παραγωγή βιοτεχνητών οργάνων.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36536102P | 2002-03-15 | 2002-03-15 | |
PCT/US2003/007852 WO2003078588A2 (en) | 2002-03-15 | 2003-03-14 | Primitive and proximal hepatic stem cells |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1118167T1 true CY1118167T1 (el) | 2017-06-28 |
Family
ID=28042021
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20161100363T CY1118167T1 (el) | 2002-03-15 | 2016-04-28 | Πρωτογενη και εγγυς ηπατικα βλαστοκυτταρα |
Country Status (18)
Country | Link |
---|---|
US (4) | US7413897B2 (el) |
EP (2) | EP3023491A1 (el) |
JP (2) | JP4723811B2 (el) |
KR (1) | KR101119878B1 (el) |
CN (3) | CN104630129A (el) |
AU (2) | AU2003233399B2 (el) |
CA (1) | CA2479510C (el) |
CY (1) | CY1118167T1 (el) |
DK (1) | DK1490480T3 (el) |
ES (1) | ES2569951T3 (el) |
HK (1) | HK1209783A1 (el) |
HU (1) | HUE032238T2 (el) |
IL (1) | IL164048A0 (el) |
MX (1) | MXPA04009031A (el) |
PL (1) | PL372619A1 (el) |
RU (1) | RU2327479C2 (el) |
SI (1) | SI1490480T1 (el) |
WO (1) | WO2003078588A2 (el) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104630129A (zh) * | 2002-03-15 | 2015-05-20 | 北卡罗来纳大学查伯山分校 | 原肝干细胞和近肝干细胞 |
JP4522994B2 (ja) | 2003-08-01 | 2010-08-11 | 憲正 中村 | スキャフォールドフリー自己組織性三次元人工組織(Scaffold−freeSelf−Organized3Dsynthetictissue) |
WO2007083504A1 (ja) * | 2003-08-01 | 2007-07-26 | Norimasa Nakamura | スキャフォールドフリー自己組織性三次元人工組織(Scaffold-free Self-Organized 3D synthetic tissue) |
EP1747265B1 (en) * | 2004-04-23 | 2011-04-20 | BioE LLC | Multi-lineage progenitor cells |
US7622108B2 (en) * | 2004-04-23 | 2009-11-24 | Bioe, Inc. | Multi-lineage progenitor cells |
WO2006126219A1 (en) * | 2005-05-26 | 2006-11-30 | Fresenius Medical Care Deutschland G.M.B.H. | Liver progenitor cells |
US20070155009A1 (en) | 2005-11-16 | 2007-07-05 | University Of North Carolina At Chapel Hill | Extracellular matrix components for expansion or differentiation of hepatic progenitors |
AU2006331706A1 (en) * | 2005-12-22 | 2007-07-05 | Vesta Therapeutics, Inc. | Method of using hepatic progenitors in treating liver dysfunction |
CA2646491A1 (en) * | 2006-04-17 | 2007-10-25 | Bioe, Inc. | Differentiation of multi-lineage progenitor cells to respiratory epithelial cells |
JP2009535035A (ja) * | 2006-04-25 | 2009-10-01 | ボード オブ スーパーバイザーズ オブ ルイジアナ ステイト ユニバーシティ アンド アグリカルチュラル アンド メカニカル カレッジ | 肝臓再生における脂肪細胞由来成体幹細胞 |
ES2664375T3 (es) * | 2006-05-26 | 2018-04-19 | The University Of North Carolina At Chapel Hill | Precursores de células estrelladas hepáticas y métodos para aislarlos |
JP2010529855A (ja) * | 2007-06-15 | 2010-09-02 | ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | 間葉系フィーダー細胞由来のパラ分泌シグナルならびにそれを用いる肝前駆体の増加および分化の調整 |
CN101835479A (zh) * | 2007-07-25 | 2010-09-15 | 佰欧益有限公司 | 多系祖细胞分化为软骨细胞 |
WO2009134773A1 (en) * | 2008-05-02 | 2009-11-05 | Vesta Therapeutics, Inc. | Hepatic progenitor cell and method of isolating same |
EP2295537A4 (en) * | 2008-05-14 | 2011-11-30 | Public Univ Corp Yokohama City | HUMAN HEPATIC STRAIN CELL, PREPARATION METHOD THEREFOR, METHOD OF INDUCING ITS DIFFERENTIATION AND METHOD OF USE |
WO2009143241A2 (en) * | 2008-05-21 | 2009-11-26 | Bioe, Inc. | Differentiation of multi-lineage progenitor cells to pancreatic cells |
KR20110051166A (ko) | 2008-05-22 | 2011-05-17 | 베스타 테라퓨틱스 인코포레이티드 | 포유동물의 전구 세포를 인슐린 생성 이자섬 세포로 분화시키는 방법 |
US20100227393A1 (en) * | 2009-03-06 | 2010-09-09 | Eric Lagasse | Liver stem cells: isolation of hepatic progenitor cells from the human gall bladder |
RU2580246C2 (ru) * | 2009-10-30 | 2016-04-10 | Дзе Юниверсити Оф Норт Каролина Эт Чапел Хилл | Мультипотентные стволовые клетки внепеченочных желчных путей и способы их выделения |
WO2012067259A1 (ja) | 2010-11-19 | 2012-05-24 | 株式会社オンチップ・バイオテクノロジーズ | 高濃度夾雑細胞群から低濃度の特定細胞を検出する方法と検出した細胞を回収し解析する方法 |
CN110511901A (zh) * | 2011-05-27 | 2019-11-29 | 德普伊新特斯产品有限责任公司 | 生物人工近端小管系统及使用方法 |
JP2015500279A (ja) | 2011-12-08 | 2015-01-05 | イェダ リサーチ アンド デベロップメント カンパニー リミテッド | 哺乳動物胎児肺細胞および該細胞の治療的使用 |
EP2864472A4 (en) * | 2012-06-20 | 2015-12-30 | Celula Inc | MATERIALS AND METHODS FOR TREATING CELLULAR POPULATIONS |
JP6510162B2 (ja) * | 2013-01-21 | 2019-05-08 | テルモ株式会社 | シート状細胞培養物の製造方法 |
US9533013B2 (en) * | 2013-03-13 | 2017-01-03 | University Of North Carolina At Chapel Hill | Method of treating pancreatic and liver conditions by endoscopic-mediated (or laparoscopic-mediated) transplantation of stem cells into/onto bile duct walls of particular regions of the biliary tree |
SG10201914005TA (en) * | 2013-09-19 | 2020-03-30 | Univ Leland Stanford Junior | Methods and compositions for producing hepatocyte-like cells |
BR112016013623B1 (pt) | 2013-12-16 | 2023-03-21 | Fresenius Medical Care Deutschland Gmbh | Método de preparação de uma estrutura de célula esferoide semelhante à ilhota pancreática cultivada artificialmente, e uso de uma estrutura de célula esferoide |
JP6595157B2 (ja) * | 2014-03-04 | 2019-10-23 | 富士フイルム株式会社 | 細胞撮像制御装置および方法並びにプログラム |
WO2016183231A1 (en) | 2015-05-12 | 2016-11-17 | Baker Group, LLP | Method and system for a bioartificial organ |
CN108431209B (zh) * | 2015-06-12 | 2023-02-10 | 新加坡科技研究局 | 肝脏干细胞的衍生和成熟肝细胞类型及其用途 |
EP4026563A1 (en) | 2015-06-18 | 2022-07-13 | Yeda Research and Development Co. Ltd | Conditioning protocols and use of same for tissue regeneration |
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US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
WO2019148143A1 (en) * | 2018-01-26 | 2019-08-01 | Polarityte, Inc. | Complex living interface-coordinated self-assembling materials (clicsam) |
EP4293109A1 (en) | 2022-06-14 | 2023-12-20 | Upside Foods, Inc. | Non-skeletal muscle-derived cells as a source of suspension capable myogenic cells for cultured foods |
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US5665589A (en) * | 1988-12-14 | 1997-09-09 | The United States Of America As Represented By The Department Of Health And Human Services | Human liver epithelial cell lines |
EP1559778A1 (en) * | 1991-08-07 | 2005-08-03 | Albert Einstein College Of Medicine Of Yeshiva University | Proliferation of hepatocyte precursors |
EP1688037A3 (en) * | 1993-11-19 | 2006-12-13 | Albert Einstein College Of Medicine Of Yeshiva University | Hepatoblasts and method of isolating same |
ZA951199B (en) * | 1994-02-14 | 1996-08-14 | Kirin Brewery | Protein having tpo activity |
US5843633A (en) * | 1996-04-26 | 1998-12-01 | Amcell Corporation | Characterization of a human hematopoietic progenitor cell antigen |
EP1071469A2 (en) * | 1998-04-17 | 2001-01-31 | Lexigen Pharmaceuticals Corp. | Enhancement of antibody-cytokine fusion protein mediated immune responses by co-administration with prostaglandin inhibitor |
US6129911A (en) * | 1998-07-10 | 2000-10-10 | Rhode Island Hospital, A Lifespan Partner | Liver stem cell |
PE20001250A1 (es) * | 1998-11-16 | 2000-11-21 | Detroit Diesel Corp | Metodo y sistema para el control de material devuelto |
JP2000287680A (ja) * | 1999-04-09 | 2000-10-17 | Sentan Kagaku Gijutsu Incubation Center:Kk | 未成熟肝細胞を成熟肝細胞へ分化させる方法 |
JP3553858B2 (ja) * | 1999-08-25 | 2004-08-11 | 東洋紡績株式会社 | 血管網類似構造体を有する細胞培養用モジュール |
KR100887623B1 (ko) | 2000-10-03 | 2009-03-11 | 유니버시티 오브 노스 캐롤라이나 | 간 전구세포의 클론 증식방법 |
CN104630129A (zh) * | 2002-03-15 | 2015-05-20 | 北卡罗来纳大学查伯山分校 | 原肝干细胞和近肝干细胞 |
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2003
- 2003-03-14 CN CN201410815377.2A patent/CN104630129A/zh active Pending
- 2003-03-14 EP EP15003527.7A patent/EP3023491A1/en not_active Withdrawn
- 2003-03-14 HU HUE03728245A patent/HUE032238T2/en unknown
- 2003-03-14 CA CA2479510A patent/CA2479510C/en not_active Expired - Lifetime
- 2003-03-14 JP JP2003576582A patent/JP4723811B2/ja not_active Expired - Lifetime
- 2003-03-14 KR KR1020047014503A patent/KR101119878B1/ko active IP Right Grant
- 2003-03-14 WO PCT/US2003/007852 patent/WO2003078588A2/en active Application Filing
- 2003-03-14 CN CN03809989.6A patent/CN1742082B/zh not_active Expired - Fee Related
- 2003-03-14 PL PL03372619A patent/PL372619A1/xx not_active Application Discontinuation
- 2003-03-14 MX MXPA04009031A patent/MXPA04009031A/es active IP Right Grant
- 2003-03-14 AU AU2003233399A patent/AU2003233399B2/en not_active Ceased
- 2003-03-14 IL IL16404803A patent/IL164048A0/xx not_active IP Right Cessation
- 2003-03-14 RU RU2005125598/15A patent/RU2327479C2/ru not_active IP Right Cessation
- 2003-03-14 US US10/387,547 patent/US7413897B2/en not_active Expired - Lifetime
- 2003-03-14 CN CNA038099896A patent/CN1742082A/zh active Granted
- 2003-03-14 ES ES03728245.6T patent/ES2569951T3/es not_active Expired - Lifetime
- 2003-03-14 SI SI200332477A patent/SI1490480T1/sl unknown
- 2003-03-14 EP EP03728245.6A patent/EP1490480B1/en not_active Expired - Lifetime
- 2003-03-14 DK DK03728245.6T patent/DK1490480T3/en active
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2006
- 2006-12-12 US US11/609,729 patent/US8691523B2/en not_active Expired - Fee Related
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2008
- 2008-06-16 AU AU2008202656A patent/AU2008202656B8/en not_active Ceased
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2010
- 2010-12-03 JP JP2010270893A patent/JP5463271B2/ja not_active Expired - Fee Related
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2014
- 2014-04-03 US US14/244,761 patent/US20140302601A1/en not_active Abandoned
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2015
- 2015-10-22 HK HK15110414.0A patent/HK1209783A1/xx unknown
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2016
- 2016-04-28 CY CY20161100363T patent/CY1118167T1/el unknown
- 2016-10-12 US US15/291,785 patent/US20170096641A1/en not_active Abandoned
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