SI1490480T1 - Primitivne in proksimalne jetrne matične celice - Google Patents

Primitivne in proksimalne jetrne matične celice

Info

Publication number
SI1490480T1
SI1490480T1 SI200332477A SI200332477A SI1490480T1 SI 1490480 T1 SI1490480 T1 SI 1490480T1 SI 200332477 A SI200332477 A SI 200332477A SI 200332477 A SI200332477 A SI 200332477A SI 1490480 T1 SI1490480 T1 SI 1490480T1
Authority
SI
Slovenia
Prior art keywords
primitive
stem cells
hepatic stem
proximal hepatic
proximal
Prior art date
Application number
SI200332477A
Other languages
English (en)
Inventor
Lola Reid
Nicholas G. Moss
Mark E. Furth
John W. Ludlow
Andrew T. Bruce
Original Assignee
University of North Carolina at Chapel Hill, Office of Commercialization and Economic Development
Vesta Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of North Carolina at Chapel Hill, Office of Commercialization and Economic Development, Vesta Therapeutics, Inc. filed Critical University of North Carolina at Chapel Hill, Office of Commercialization and Economic Development
Publication of SI1490480T1 publication Critical patent/SI1490480T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • C12N5/0672—Stem cells; Progenitor cells; Precursor cells; Oval cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/36—Lipids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SI200332477A 2002-03-15 2003-03-14 Primitivne in proksimalne jetrne matične celice SI1490480T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36536102P 2002-03-15 2002-03-15
PCT/US2003/007852 WO2003078588A2 (en) 2002-03-15 2003-03-14 Primitive and proximal hepatic stem cells
EP03728245.6A EP1490480B1 (en) 2002-03-15 2003-03-14 Primitive and proximal hepatic stem cells

Publications (1)

Publication Number Publication Date
SI1490480T1 true SI1490480T1 (sl) 2016-06-30

Family

ID=28042021

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200332477A SI1490480T1 (sl) 2002-03-15 2003-03-14 Primitivne in proksimalne jetrne matične celice

Country Status (18)

Country Link
US (4) US7413897B2 (sl)
EP (2) EP1490480B1 (sl)
JP (2) JP4723811B2 (sl)
KR (1) KR101119878B1 (sl)
CN (3) CN1742082B (sl)
AU (2) AU2003233399B2 (sl)
CA (1) CA2479510C (sl)
CY (1) CY1118167T1 (sl)
DK (1) DK1490480T3 (sl)
ES (1) ES2569951T3 (sl)
HK (1) HK1209783A1 (sl)
HU (1) HUE032238T2 (sl)
IL (1) IL164048A0 (sl)
MX (1) MXPA04009031A (sl)
PL (1) PL372619A1 (sl)
RU (1) RU2327479C2 (sl)
SI (1) SI1490480T1 (sl)
WO (1) WO2003078588A2 (sl)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL164048A0 (en) * 2002-03-15 2005-12-18 Univ North Carolina Primitive and proximal hepatic stemcells
WO2005012512A1 (en) 2003-08-01 2005-02-10 Norimasa Nakamura Scaffold-free self-organized 3d synthetic tissue
WO2007083504A1 (ja) * 2003-08-01 2007-07-26 Norimasa Nakamura スキャフォールドフリー自己組織性三次元人工組織（Ｓｃａｆｆｏｌｄ－ｆｒｅｅ Ｓｅｌｆ－Ｏｒｇａｎｉｚｅｄ ３Ｄ ｓｙｎｔｈｅｔｉｃ ｔｉｓｓｕｅ）
US7622108B2 (en) * 2004-04-23 2009-11-24 Bioe, Inc. Multi-lineage progenitor cells
ATE506431T1 (de) * 2004-04-23 2011-05-15 Bioe Llc Mehrfachlinien-vorläuferzellen
WO2006126219A1 (en) * 2005-05-26 2006-11-30 Fresenius Medical Care Deutschland G.M.B.H. Liver progenitor cells
CA2630355A1 (en) * 2005-11-16 2007-05-24 University Of North Carolina At Chapel Hill Extracellular matrix components for expansion or differentiation of hepatic progenitors
RU2008130098A (ru) * 2005-12-22 2010-01-27 Веста Терапьютикс, Инк. (Us) Способ лечения нарушения функции печени с использованием печеночных клеток-предшественников
US7727763B2 (en) * 2006-04-17 2010-06-01 Bioe, Llc Differentiation of multi-lineage progenitor cells to respiratory epithelial cells
WO2007127698A2 (en) * 2006-04-25 2007-11-08 Board Of Supervisors Of Louisiana State Universityand Agricultural And Mechanical College Adipose derived adult stem cells in hepatic regeneration
PT2029725T (pt) 2006-05-26 2018-04-12 Univ North Carolina Chapel Hill Precursores de células hepáticas estreladas e métodos para isolar as mesmas
IN2010KN00157A (sl) * 2007-06-15 2015-08-28 Univ North Carolina
EP2192908A4 (en) * 2007-07-25 2010-09-01 Bioe Inc DIFFERENTIATION OF PRECURSOR CELLS OF MULTIPLE ABSTRACTS AGAINST CHONDROCYTES
US20100087000A1 (en) * 2008-05-02 2010-04-08 Vesta Therapeutics, Inc. Hepatic progenitor cell and method of isolating same
JP5822287B2 (ja) * 2008-05-14 2015-11-24 公立大学法人横浜市立大学 ヒト肝幹細胞、その調製方法、分化誘導方法及び利用方法
CA2724839A1 (en) * 2008-05-21 2009-11-26 Bioe Llc Differentiation of multi-lineage progenitor cells to pancreatic cells
MX2010012730A (es) 2008-05-22 2011-03-01 Vesta Therapeutics Inc Metodo para diferenciacion de celulas progenitoras de mamifero en celulas de islote pancreaticas que producen insulina.
US20100227393A1 (en) * 2009-03-06 2010-09-09 Eric Lagasse Liver stem cells: isolation of hepatic progenitor cells from the human gall bladder
BR112012009848B1 (pt) * 2009-10-30 2021-11-03 The University Of North Carolina At Chapel Hill Método de obtenção de células-tronco/progenitoras multipotentes de mamíferos capazes de se diferenciar em linhagens hepáticas e pancreáticas
US9341550B2 (en) * 2010-11-19 2016-05-17 On-Chip Biotechnologies Co., Ltd. Method for detecting low concentrations of specific cell from high concentrations of cell populations, and method for collecting and analyzing detected cell
AU2012262382B2 (en) * 2011-05-27 2016-10-13 DePuy Synthes Products, Inc. Bioartificial proximal tubule systems and methods of use
CN104105493A (zh) 2011-12-08 2014-10-15 耶达研究及发展有限公司 哺乳动物胎儿肺细胞以及其治疗用途
WO2013192342A1 (en) * 2012-06-20 2013-12-27 Celula, Inc. Materials and methods for processing cell populations
JP6510162B2 (ja) * 2013-01-21 2019-05-08 テルモ株式会社 シート状細胞培養物の製造方法
US9533013B2 (en) * 2013-03-13 2017-01-03 University Of North Carolina At Chapel Hill Method of treating pancreatic and liver conditions by endoscopic-mediated (or laparoscopic-mediated) transplantation of stem cells into/onto bile duct walls of particular regions of the biliary tree
EP3685884A1 (en) * 2013-09-19 2020-07-29 The Board of Trustees of the Leland Stanford Junior University Methods and compositions for producing hepatocyte-like cells
JP6643993B2 (ja) 2013-12-16 2020-02-12 フレゼニウス メディカル ケア ドイッチェランド ゲゼルシャフト ミット ベシュレンクテル ハフツング 膵島様細胞構造体及びそれを調製する方法
JP6595157B2 (ja) * 2014-03-04 2019-10-23 富士フイルム株式会社 細胞撮像制御装置および方法並びにプログラム
US10179896B2 (en) 2015-05-12 2019-01-15 Baker Group, LLP Method and system for a bioartificial organ
WO2016200340A1 (en) * 2015-06-12 2016-12-15 Agency For Science, Technology And Research Derivation of hepatic stem cells and mature liver cell types and uses thereof
US10668109B2 (en) 2015-06-18 2020-06-02 Yeda Research And Development Co. Ltd. Conditioning protocols and use of same for tissue regeneration
CN105483077A (zh) * 2015-12-24 2016-04-13 福州市传染病医院 一种提高肝细胞增殖活性的细胞培养方法
JP2019134682A (ja) * 2016-06-01 2019-08-15 国立研究開発法人医薬基盤・健康・栄養研究所 肝幹細胞様細胞の調製方法
US10767164B2 (en) 2017-03-30 2020-09-08 The Research Foundation For The State University Of New York Microenvironments for self-assembly of islet organoids from stem cells differentiation
EP3743080A4 (en) * 2018-01-26 2021-10-27 Polarityte, Inc. SELF-ASSEMBLY MATERIALS COORDINATED WITH A COMPLEX LIVING INTERFACE (CLICSAM)
EP4293109A1 (en) 2022-06-14 2023-12-20 Upside Foods, Inc. Non-skeletal muscle-derived cells as a source of suspension capable myogenic cells for cultured foods

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5665589A (en) * 1988-12-14 1997-09-09 The United States Of America As Represented By The Department Of Health And Human Services Human liver epithelial cell lines
EP0597964A4 (en) * 1991-08-07 1994-11-30 Einstein Coll Med PROLIFERATION OF HEPATOCYTE PRECURSORS.
EP1688037A3 (en) * 1993-11-19 2006-12-13 Albert Einstein College Of Medicine Of Yeshiva University Hepatoblasts and method of isolating same
ZA951199B (en) * 1994-02-14 1996-08-14 Kirin Brewery Protein having tpo activity
US5843633A (en) * 1996-04-26 1998-12-01 Amcell Corporation Characterization of a human hematopoietic progenitor cell antigen
HUP0101343A3 (en) * 1998-04-17 2003-10-28 Lexigen Pharmaceuticals Corp L Enhancement of antibody-cytokine fusion protein mediated immune responses by co-administration with prostaglandin inhibitor
US6129911A (en) 1998-07-10 2000-10-10 Rhode Island Hospital, A Lifespan Partner Liver stem cell
PE20001250A1 (es) * 1998-11-16 2000-11-21 Detroit Diesel Corp Metodo y sistema para el control de material devuelto
JP2000287680A (ja) * 1999-04-09 2000-10-17 Sentan Kagaku Gijutsu Incubation Center:Kk 未成熟肝細胞を成熟肝細胞へ分化させる方法
JP3553858B2 (ja) * 1999-08-25 2004-08-11 東洋紡績株式会社 血管網類似構造体を有する細胞培養用モジュール
CA2424779C (en) * 2000-10-03 2016-08-23 University Of North Carolina At Chapel Hill Processes for clonal growth of hepatic progenitor cells
IL164048A0 (en) * 2002-03-15 2005-12-18 Univ North Carolina Primitive and proximal hepatic stemcells

Also Published As

Publication number Publication date
KR20060010693A (ko) 2006-02-02
AU2008202656A1 (en) 2008-07-10
CN1742082A (zh) 2006-03-01
US20040018621A1 (en) 2004-01-29
EP1490480B1 (en) 2016-02-03
AU2008202656B8 (en) 2011-12-15
JP5463271B2 (ja) 2014-04-09
CN1742082B (zh) 2015-01-21
IL164048A0 (en) 2005-12-18
JP2011087591A (ja) 2011-05-06
US20070099297A1 (en) 2007-05-03
EP1490480A2 (en) 2004-12-29
AU2008202656B2 (en) 2011-03-17
EP3023491A1 (en) 2016-05-25
US20140302601A1 (en) 2014-10-09
ES2569951T3 (es) 2016-05-13
JP4723811B2 (ja) 2011-07-13
RU2327479C2 (ru) 2008-06-27
CY1118167T1 (el) 2017-06-28
MXPA04009031A (es) 2005-12-12
AU2008202656A8 (en) 2011-12-15
US7413897B2 (en) 2008-08-19
US20170096641A1 (en) 2017-04-06
JP2005520513A (ja) 2005-07-14
CA2479510C (en) 2019-10-29
WO2003078588A3 (en) 2004-04-01
EP1490480A4 (en) 2006-06-14
WO2003078588A9 (en) 2003-12-11
HK1209783A1 (en) 2016-04-08
CN104630129A (zh) 2015-05-20
US8691523B2 (en) 2014-04-08
CA2479510A1 (en) 2003-09-25
AU2003233399B2 (en) 2008-03-20
AU2003233399A1 (en) 2003-09-29
HUE032238T2 (en) 2017-09-28
PL372619A1 (en) 2005-07-25
KR101119878B1 (ko) 2012-03-09
RU2005125598A (ru) 2006-01-27
DK1490480T3 (en) 2016-04-11
WO2003078588A2 (en) 2003-09-25

Similar Documents

Publication Publication Date Title
HK1209783A1 (en) Primitive and proximal hepatic stem cells
EP1689854A4 (en) PLACENTAR STEM CELLS AND USES THEREOF
TWI316092B (en) Alloy and its use
PT2702871T (pt) Biotecido de colagénio e sua utilização
AU2003239159A8 (en) Placental derived stem cells and uses thereof
EP1539941A4 (en) ADZYMES AND THEIR USES
EP1539003A4 (en) MICRODERMABRASION COMPOSITION AND SET
IL174479A0 (en) Hemiasterlin derivatives and uses thereof
EP1551384A4 (en) R-NSAID ESTERS AND ITS USE
IL163868A0 (en) Hermiasterlin derivatives and uses thereof
GB2359641B (en) Mapping circuitry and method
EP1581637A4 (en) MATERIALS AND METHODS WITH HUMAN STEM CELLS
EP1689629A4 (en) WHEELCHAIR CONSTRUCTIONS AND RELATED IMPROVEMENTS
AU2003296369A8 (en) Imminoamines and preparation thereof
IL173342A0 (en) Entrapped stem cells and uses thereof
EP1616873A4 (en) LIPID REGULATING MEDIUM AND ITS USE
GB0301009D0 (en) Laryngoscopes and parts thereof
EP1467673A4 (en) IRRIGATION SOLUTION AND METHODS OF USE
AU2003231827A8 (en) Pseudo-tissues and uses thereof
GB0318546D0 (en) Quinoxalinones and their use
AU2003263895A8 (en) Contraceptive methods and formulations
AU2003302173A8 (en) Spirotetrathiocarbamates and spirooxothiocarbamates
AU2003272717A8 (en) Frozen spermatozoa compositions and uses thereof
GB0317985D0 (en) Plant and plant extracts and their use
GB0220776D0 (en) FOXP2 and uses thereof