CY1115055T1 - Παραγωγα καρβοξυλικου οξεος με ενα 2,5-υποκατεστημενο δακτυλιο οξαζολοπυριμιδινης - Google Patents
Παραγωγα καρβοξυλικου οξεος με ενα 2,5-υποκατεστημενο δακτυλιο οξαζολοπυριμιδινηςInfo
- Publication number
- CY1115055T1 CY1115055T1 CY20141100079T CY141100079T CY1115055T1 CY 1115055 T1 CY1115055 T1 CY 1115055T1 CY 20141100079 T CY20141100079 T CY 20141100079T CY 141100079 T CY141100079 T CY 141100079T CY 1115055 T1 CY1115055 T1 CY 1115055T1
- Authority
- CY
- Cyprus
- Prior art keywords
- carboxylic acid
- acid producers
- oxazolopyrimidine ring
- substituted oxazolopyrimidine
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Η εφεύρεση αφορά σε ενώσεις οξαζολοπυριμιδίνης του τύπου Ι, όπου τα Α, R1, R2, R3 και X έχουν όπως ορίζεται στις αξιώσεις. Οι ενώσεις του τύπου Ι ενδείκνυνται, επί παραδείγματι, για την επούλωση τραυμάτων.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10305042 | 2010-01-14 | ||
EP11700404.4A EP2523962B1 (de) | 2010-01-14 | 2011-01-12 | Carbonsäurederivate mit einem 2,5-substituierten oxazolopyrimidinring |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1115055T1 true CY1115055T1 (el) | 2016-12-14 |
Family
ID=41800578
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20141100079T CY1115055T1 (el) | 2010-01-14 | 2014-01-30 | Παραγωγα καρβοξυλικου οξεος με ενα 2,5-υποκατεστημενο δακτυλιο οξαζολοπυριμιδινης |
Country Status (31)
Country | Link |
---|---|
US (1) | US8846692B2 (el) |
EP (1) | EP2523962B1 (el) |
JP (1) | JP5841067B2 (el) |
KR (1) | KR101759128B1 (el) |
CN (1) | CN102791717B (el) |
AR (1) | AR079997A1 (el) |
AU (1) | AU2011206615B2 (el) |
BR (1) | BR112012017437B1 (el) |
CA (1) | CA2784560C (el) |
CL (1) | CL2012001972A1 (el) |
CO (1) | CO6612239A2 (el) |
CY (1) | CY1115055T1 (el) |
DK (1) | DK2523962T3 (el) |
ES (1) | ES2441954T3 (el) |
HK (1) | HK1178885A1 (el) |
HR (1) | HRP20140179T1 (el) |
IL (1) | IL220720A (el) |
MA (1) | MA33917B1 (el) |
MX (1) | MX2012007834A (el) |
MY (1) | MY156550A (el) |
NZ (1) | NZ601113A (el) |
PL (1) | PL2523962T3 (el) |
PT (1) | PT2523962E (el) |
RS (1) | RS53254B (el) |
RU (1) | RU2564018C2 (el) |
SG (1) | SG182484A1 (el) |
SI (1) | SI2523962T1 (el) |
TW (1) | TWI510242B (el) |
UY (1) | UY33179A (el) |
WO (1) | WO2011086079A1 (el) |
ZA (1) | ZA201204174B (el) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UY33177A (es) | 2010-01-13 | 2011-08-31 | Sanofi Aventis | Derivados de ácido carboxílico que comprenden un anillo de oxazolopirimidina 2, 5, 7-sustituido |
TWI485153B (zh) | 2010-01-13 | 2015-05-21 | Sanofi Aventis | 2,5,7-經取代唑并嘧啶衍生物 |
WO2011086081A1 (de) * | 2010-01-14 | 2011-07-21 | Sanofi-Aventis | 2,5-substituierte oxazolopyrimidinderivate |
AR079884A1 (es) * | 2010-01-14 | 2012-02-29 | Sanofi Aventis | Derivados de acido carboxilico heterociclicos que comprenden un anillo de oxazolopirimidina 2,5-sustituida |
US9321787B2 (en) * | 2011-07-07 | 2016-04-26 | Sanofi | Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring |
EP2862574A1 (en) * | 2013-10-15 | 2015-04-22 | Sanofi | {4-[5-(3-chloro-phenoxy)-oxazolo[5,4 d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-acetic acid for use in the prevention or treatment of acute kidney injury |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3679682A (en) * | 1970-04-23 | 1972-07-25 | Fmc Corp | CERTAIN 5H-ISOXAZOLO{8 5,4-d{9 PYRIMIDIN-4-ONES |
JPH01242587A (ja) * | 1988-03-25 | 1989-09-27 | Sankyo Co Ltd | 縮環オキサゾロチエノピリミジン誘導体 |
CA2523739A1 (en) * | 2003-04-25 | 2004-11-11 | University College Cardiff Consultants Limited | Heterocyclic compounds for use in the treatment of viral infections |
EP1622866B1 (en) * | 2003-04-30 | 2012-07-25 | Novartis AG | Aminopropanol derivatives as sphingosine-1-phosphate receptor modulators |
CN1787817B (zh) * | 2003-05-19 | 2011-09-07 | Irm责任有限公司 | 免疫抑制剂化合物及组合物 |
CA2524048C (en) * | 2003-05-19 | 2013-06-25 | Irm Llc | Immunosuppressant compounds and compositions |
CN101291908A (zh) * | 2005-08-23 | 2008-10-22 | Irm责任有限公司 | 免疫抑制剂化合物和组合物 |
EP2121648A2 (en) * | 2007-03-21 | 2009-11-25 | EPIX Pharmaceuticals, Inc. | S1p receptor modulating compounds and use thereof |
TW201000099A (en) * | 2008-06-20 | 2010-01-01 | Amgen Inc | S1P1 receptor agonists and use thereof |
RU2503680C2 (ru) * | 2008-07-15 | 2014-01-10 | Санофи-Авентис | ОКСАЗОЛОПИРИМИДИНЫ КАК АГОНИСТЫ РЕЦЕПТОРА Edg-1 |
TWI485153B (zh) * | 2010-01-13 | 2015-05-21 | Sanofi Aventis | 2,5,7-經取代唑并嘧啶衍生物 |
UY33177A (es) * | 2010-01-13 | 2011-08-31 | Sanofi Aventis | Derivados de ácido carboxílico que comprenden un anillo de oxazolopirimidina 2, 5, 7-sustituido |
TWI517851B (zh) * | 2010-01-13 | 2016-01-21 | 賽諾菲阿凡提斯公司 | 含2,5,7-經取代唑并嘧啶環之雜環羧酸衍生物 |
AR079884A1 (es) * | 2010-01-14 | 2012-02-29 | Sanofi Aventis | Derivados de acido carboxilico heterociclicos que comprenden un anillo de oxazolopirimidina 2,5-sustituida |
WO2011086081A1 (de) * | 2010-01-14 | 2011-07-21 | Sanofi-Aventis | 2,5-substituierte oxazolopyrimidinderivate |
-
2011
- 2011-01-12 WO PCT/EP2011/050301 patent/WO2011086079A1/de active Application Filing
- 2011-01-12 NZ NZ601113A patent/NZ601113A/xx unknown
- 2011-01-12 US US13/521,831 patent/US8846692B2/en active Active
- 2011-01-12 ES ES11700404.4T patent/ES2441954T3/es active Active
- 2011-01-12 KR KR1020127021242A patent/KR101759128B1/ko active IP Right Grant
- 2011-01-12 PT PT117004044T patent/PT2523962E/pt unknown
- 2011-01-12 PL PL11700404T patent/PL2523962T3/pl unknown
- 2011-01-12 MY MYPI2012002588A patent/MY156550A/en unknown
- 2011-01-12 MX MX2012007834A patent/MX2012007834A/es active IP Right Grant
- 2011-01-12 SG SG2012051405A patent/SG182484A1/en unknown
- 2011-01-12 EP EP11700404.4A patent/EP2523962B1/de active Active
- 2011-01-12 DK DK11700404.4T patent/DK2523962T3/en active
- 2011-01-12 RU RU2012134630/04A patent/RU2564018C2/ru active
- 2011-01-12 TW TW100101053A patent/TWI510242B/zh active
- 2011-01-12 MA MA35055A patent/MA33917B1/fr unknown
- 2011-01-12 JP JP2012548410A patent/JP5841067B2/ja active Active
- 2011-01-12 UY UY0001033179A patent/UY33179A/es not_active Application Discontinuation
- 2011-01-12 CA CA2784560A patent/CA2784560C/en active Active
- 2011-01-12 CN CN201180013877.9A patent/CN102791717B/zh active Active
- 2011-01-12 AU AU2011206615A patent/AU2011206615B2/en active Active
- 2011-01-12 RS RS20140062A patent/RS53254B/en unknown
- 2011-01-12 AR ARP110100092A patent/AR079997A1/es active IP Right Grant
- 2011-01-12 SI SI201130094T patent/SI2523962T1/sl unknown
- 2011-01-12 BR BR112012017437-1A patent/BR112012017437B1/pt active IP Right Grant
-
2012
- 2012-06-07 ZA ZA2012/04174A patent/ZA201204174B/en unknown
- 2012-07-02 IL IL220720A patent/IL220720A/en active IP Right Grant
- 2012-07-13 CL CL2012001972A patent/CL2012001972A1/es unknown
- 2012-07-26 CO CO12125684A patent/CO6612239A2/es unknown
-
2013
- 2013-05-10 HK HK13105591.7A patent/HK1178885A1/xx unknown
-
2014
- 2014-01-30 CY CY20141100079T patent/CY1115055T1/el unknown
- 2014-02-26 HR HRP20140179AT patent/HRP20140179T1/hr unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1117878T1 (el) | Πυριδινo-2-αμιδια χρησιμα ως αγωνιστες του cb2 | |
CY1115055T1 (el) | Παραγωγα καρβοξυλικου οξεος με ενα 2,5-υποκατεστημενο δακτυλιο οξαζολοπυριμιδινης | |
CY1121586T1 (el) | Αντιοξειδωτικοι ρυθμιστες της φλεγμονης: παραγωγα ελαιανολικου οξεος με αμινικη και αλλες τροποποιησεις στο c-17 | |
CY1116602T1 (el) | Παραγωγα υδροξαμικου οξεος | |
CY1118475T1 (el) | Αντιοξειδωτικοι ρυθμιστες φλεγμονης: c-17 ομολογοποιημενα παραγωγα ολεανολικου οξεος | |
CY1117956T1 (el) | N3-αντικατεστημενα-n1-sulfonyl-5-fluoropyrimidinone παραγωγα | |
CY1116945T1 (el) | Παραγωγα ινδολιζινης, διεργασια για την παρασκευη αυτης και θεραπευτικη χρηση αυτης | |
CY1118950T1 (el) | Νεα παραγωγα πυραζολιου | |
CY1115945T1 (el) | Παραγωγα πυραζολοκινολινονης, η παρασκευη τους και η θεραπευτικη τους χρηση | |
EA201691085A1 (ru) | Замещенные бензамиды и способы их применения | |
MX341133B (es) | Compuestos y metodos para la inhibición de hdac. | |
CY1118593T1 (el) | Πρωτοτυπα παραγωγα πυραζινης | |
UA110338C2 (en) | Chemical compounds | |
EA201000950A1 (ru) | Азолилметилоксираны, их применение, а также содержащие их средства | |
EA201391303A1 (ru) | Амиды n-(1,2,5-оксадиазол-3-ил)-, n-(тетразол-5-ил)- и n-(триазол-5-ил)бициклоарилкарбоновых кислот и их применение в качестве гербицидов | |
CY1118883T1 (el) | Μεθοδος παρασκευης βορτιοξετινης | |
MA33948B1 (fr) | Dérivés d'acide 3-hétéroaroylamino-propionique substitues par oxygène et leur utilisation en tant qu'agents pharmaceutiques. | |
MY156525A (en) | 2,5,7-substituted oxazolopyrimidine derivatives | |
CY1111914T1 (el) | Μεθοδος συνθεσης της ιβαβραδινης και των αλατων προσθηκης αυτης με ενα φαρμακευτικως αποδεκτο οξυ | |
CR20110403A (es) | Derivados de tiadiazoles y oxadiazoles, su preparación y su aplicación en terapia | |
MX2012007870A (es) | Derivados de acido carboxilico que comprende un anillo de oxazolopirimidina 2, 5, 7-sustituido. | |
MY156476A (en) | Heterocyclic carboxylic acid derivatives having a 2,5-substituted oxazolopyrimidine ring | |
MX2012007833A (es) | Derivados de acido carboxilico heterociclicos que contienen un anillo de oxazolopirimidina 2, 5, 7 - sustituido. | |
MX2012007837A (es) | Derivados de oxazolopirimidina 2, 5 - sustituidos. | |
CY1112855T1 (el) | Παραγωγα των πυρρολοπυριδινο-2-καρβοξαμιδιων, η παρασκευη τους και η θεραπευτικη εφαρμογη τους |