MX2012007833A - Derivados de acido carboxilico heterociclicos que contienen un anillo de oxazolopirimidina 2, 5, 7 - sustituido. - Google Patents
Derivados de acido carboxilico heterociclicos que contienen un anillo de oxazolopirimidina 2, 5, 7 - sustituido.Info
- Publication number
- MX2012007833A MX2012007833A MX2012007833A MX2012007833A MX2012007833A MX 2012007833 A MX2012007833 A MX 2012007833A MX 2012007833 A MX2012007833 A MX 2012007833A MX 2012007833 A MX2012007833 A MX 2012007833A MX 2012007833 A MX2012007833 A MX 2012007833A
- Authority
- MX
- Mexico
- Prior art keywords
- carboxylic acid
- acid derivatives
- heterocyclic carboxylic
- oxazolopyrimidine ring
- substituted oxazolopyrimidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
La invención se refiere a compuestos de oxazolopirimidina de fórmula (I), (ver fórmula (I)) en la que A, R1, R2, R3, R4, X e Y se definen como se ha indicado en las reivindicaciones. Los compuestos de fórmula I son adecuados, p. ej., para la curación de heridas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10305037 | 2010-01-13 | ||
| PCT/EP2011/050299 WO2011086078A1 (de) | 2010-01-13 | 2011-01-12 | Heterocyclische carbonsäurederivate mit einem 2,5,7-substituiertem oxazolopyrimidinring |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2012007833A true MX2012007833A (es) | 2012-07-20 |
Family
ID=41820658
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012007833A MX2012007833A (es) | 2010-01-13 | 2011-01-12 | Derivados de acido carboxilico heterociclicos que contienen un anillo de oxazolopirimidina 2, 5, 7 - sustituido. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8846691B2 (es) |
| EP (1) | EP2523959B1 (es) |
| JP (1) | JP5844278B2 (es) |
| KR (1) | KR101759121B1 (es) |
| CN (1) | CN102906098B (es) |
| AR (1) | AR079982A1 (es) |
| AU (1) | AU2011206614B8 (es) |
| BR (1) | BR112012017240A2 (es) |
| CA (1) | CA2792134C (es) |
| DK (1) | DK2523959T3 (es) |
| ES (1) | ES2449705T3 (es) |
| HK (1) | HK1178888A1 (es) |
| IL (1) | IL220708A (es) |
| MX (1) | MX2012007833A (es) |
| MY (1) | MY156551A (es) |
| PT (1) | PT2523959E (es) |
| RU (1) | RU2554869C2 (es) |
| SG (1) | SG182473A1 (es) |
| TW (1) | TWI517851B (es) |
| UY (1) | UY33178A (es) |
| WO (1) | WO2011086078A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY33176A (es) | 2010-01-13 | 2011-08-31 | Sanofi Aventis | Derivados de oxazolopirimidina sustituida en 2, 5, 7. |
| PT2523960E (pt) * | 2010-01-14 | 2013-12-09 | Sanofi Sa | Derivados heterocíclicos de ácidos carboxílicos com um anel oxazolopirimidina substituído em 2,5 |
| SG182483A1 (en) * | 2010-01-14 | 2012-08-30 | Sanofi Sa | 2,5-substituted oxazolopyrimidine derivatives |
| EP2523962B1 (de) * | 2010-01-14 | 2013-11-27 | Sanofi | Carbonsäurederivate mit einem 2,5-substituierten oxazolopyrimidinring |
| US9321787B2 (en) | 2011-07-07 | 2016-04-26 | Sanofi | Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3679682A (en) * | 1970-04-23 | 1972-07-25 | Fmc Corp | CERTAIN 5H-ISOXAZOLO{8 5,4-d{9 PYRIMIDIN-4-ONES |
| US7417065B2 (en) * | 2003-05-19 | 2008-08-26 | Irm Llc | Immunosuppressant compounds and compositions |
| CN1791592B (zh) * | 2003-05-19 | 2012-07-04 | Irm责任有限公司 | 免疫抑制剂化合物和组合物 |
| CA2630714C (en) * | 2005-11-23 | 2014-01-14 | Epix Delaware, Inc. | S1p receptor modulating compounds and use thereof |
| MX2009010060A (es) * | 2007-03-21 | 2010-01-20 | Epix Pharm Inc | Compuestos moduladores del receptor de esfingosin-1-fosfato y uso de los mismos. |
| TW201000099A (en) * | 2008-06-20 | 2010-01-01 | Amgen Inc | S1P1 receptor agonists and use thereof |
-
2011
- 2011-01-11 AR ARP110100075A patent/AR079982A1/es unknown
- 2011-01-11 TW TW100100891A patent/TWI517851B/zh not_active IP Right Cessation
- 2011-01-11 UY UY0001033178A patent/UY33178A/es not_active Application Discontinuation
- 2011-01-12 CN CN201180013919.9A patent/CN102906098B/zh active Active
- 2011-01-12 AU AU2011206614A patent/AU2011206614B8/en not_active Ceased
- 2011-01-12 JP JP2012548409A patent/JP5844278B2/ja active Active
- 2011-01-12 DK DK11700136.2T patent/DK2523959T3/en active
- 2011-01-12 WO PCT/EP2011/050299 patent/WO2011086078A1/de active Application Filing
- 2011-01-12 ES ES11700136.2T patent/ES2449705T3/es active Active
- 2011-01-12 KR KR1020127021141A patent/KR101759121B1/ko active IP Right Grant
- 2011-01-12 CA CA2792134A patent/CA2792134C/en not_active Expired - Fee Related
- 2011-01-12 US US13/521,829 patent/US8846691B2/en active Active
- 2011-01-12 RU RU2012134463/04A patent/RU2554869C2/ru not_active IP Right Cessation
- 2011-01-12 MY MYPI2012002589A patent/MY156551A/en unknown
- 2011-01-12 SG SG2012051165A patent/SG182473A1/en unknown
- 2011-01-12 MX MX2012007833A patent/MX2012007833A/es active IP Right Grant
- 2011-01-12 BR BR112012017240A patent/BR112012017240A2/pt not_active IP Right Cessation
- 2011-01-12 EP EP11700136.2A patent/EP2523959B1/de active Active
- 2011-01-12 PT PT117001362T patent/PT2523959E/pt unknown
-
2012
- 2012-07-01 IL IL220708A patent/IL220708A/en not_active IP Right Cessation
-
2013
- 2013-05-10 HK HK13105594.4A patent/HK1178888A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN102906098A (zh) | 2013-01-30 |
| KR20120101593A (ko) | 2012-09-13 |
| JP2013517240A (ja) | 2013-05-16 |
| KR101759121B1 (ko) | 2017-07-18 |
| AU2011206614B8 (en) | 2015-03-05 |
| CN102906098B (zh) | 2015-07-15 |
| HK1178888A1 (en) | 2013-09-19 |
| RU2012134463A (ru) | 2014-02-20 |
| MY156551A (en) | 2016-02-26 |
| UY33178A (es) | 2011-08-31 |
| EP2523959B1 (de) | 2013-11-27 |
| PT2523959E (pt) | 2014-03-10 |
| TW201134472A (en) | 2011-10-16 |
| CA2792134C (en) | 2017-12-05 |
| TWI517851B (zh) | 2016-01-21 |
| AU2011206614A1 (en) | 2012-08-02 |
| WO2011086078A1 (de) | 2011-07-21 |
| US8846691B2 (en) | 2014-09-30 |
| EP2523959A1 (de) | 2012-11-21 |
| SG182473A1 (en) | 2012-08-30 |
| AU2011206614B2 (en) | 2015-02-26 |
| AR079982A1 (es) | 2012-03-07 |
| JP5844278B2 (ja) | 2016-01-13 |
| IL220708A (en) | 2015-02-26 |
| ES2449705T3 (es) | 2014-03-20 |
| RU2554869C2 (ru) | 2015-06-27 |
| BR112012017240A2 (pt) | 2016-03-22 |
| US20130158051A1 (en) | 2013-06-20 |
| CA2792134A1 (en) | 2011-07-21 |
| DK2523959T3 (en) | 2014-03-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |