MX2012007836A - Derivados de acido carboxilico heterociclicos que comprenden un anillo de oxazolopirimidina 2,5-sustituida. - Google Patents

Derivados de acido carboxilico heterociclicos que comprenden un anillo de oxazolopirimidina 2,5-sustituida.

Info

Publication number
MX2012007836A
MX2012007836A MX2012007836A MX2012007836A MX2012007836A MX 2012007836 A MX2012007836 A MX 2012007836A MX 2012007836 A MX2012007836 A MX 2012007836A MX 2012007836 A MX2012007836 A MX 2012007836A MX 2012007836 A MX2012007836 A MX 2012007836A
Authority
MX
Mexico
Prior art keywords
carboxylic acid
acid derivatives
heterocyclic carboxylic
oxazolopyrimidine ring
substituted oxazolopyrimidine
Prior art date
Application number
MX2012007836A
Other languages
English (en)
Inventor
Matthias Schaefer
Dieter Kadereit
Stephanie Hachtel
Axel Dietrich
Thomas Huebschle
Katrin Hiss
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of MX2012007836A publication Critical patent/MX2012007836A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente invención se refiere a compuestos de oxazolopirimidina de la fórmula I, (ver fórmula (I)) en la que A, R1, R2 y R3 se definen como se ha indicado en las reivindicaciones. Los compuestos de la fórmula I son adecuados, por ejemplo, para la curación de heridas.
MX2012007836A 2010-01-14 2011-01-12 Derivados de acido carboxilico heterociclicos que comprenden un anillo de oxazolopirimidina 2,5-sustituida. MX2012007836A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10305043 2010-01-14
PCT/EP2011/050302 WO2011086080A1 (de) 2010-01-14 2011-01-12 Heterocyclische carbonsäurederivate mit einem 2,5-substituierten oxazolopyrimidinring

Publications (1)

Publication Number Publication Date
MX2012007836A true MX2012007836A (es) 2012-07-30

Family

ID=41820700

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012007836A MX2012007836A (es) 2010-01-14 2011-01-12 Derivados de acido carboxilico heterociclicos que comprenden un anillo de oxazolopirimidina 2,5-sustituida.

Country Status (21)

Country Link
US (1) US8846690B2 (es)
EP (1) EP2523960B1 (es)
JP (1) JP5841068B2 (es)
KR (1) KR101759127B1 (es)
CN (1) CN102834399B (es)
AR (1) AR079884A1 (es)
AU (1) AU2011206616B2 (es)
BR (1) BR112012017447B1 (es)
CA (1) CA2804128C (es)
DK (1) DK2523960T3 (es)
ES (1) ES2437471T3 (es)
HK (1) HK1178886A1 (es)
IL (1) IL220718A (es)
MX (1) MX2012007836A (es)
MY (1) MY156476A (es)
PT (1) PT2523960E (es)
RU (1) RU2559896C2 (es)
SG (1) SG182474A1 (es)
TW (1) TWI482623B (es)
UY (1) UY33180A (es)
WO (1) WO2011086080A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI485153B (zh) 2010-01-13 2015-05-21 Sanofi Aventis ２，５，７－經取代唑并嘧啶衍生物
AR079981A1 (es) 2010-01-13 2012-03-07 Sanofi Aventis Derivados de acido carboxilico que comprenden un anillo de oxoazolopirimidina 2,5,7- sustituido
AU2011206615B2 (en) * 2010-01-14 2015-03-19 Sanofi Carboxylic acid derivatives having A 2,5-substituted oxazolopyrimidine ring
MY159857A (en) 2010-01-14 2017-02-15 Sanofi Sa 2,5-substituted oxazolopyrimidine derivatives
US9309019B2 (en) 2010-05-21 2016-04-12 Adhezion Biomedical, Llc Low dose gamma sterilization of liquid adhesives
US9321787B2 (en) 2011-07-07 2016-04-26 Sanofi Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3679682A (en) * 1970-04-23 1972-07-25 Fmc Corp CERTAIN 5H-ISOXAZOLO{8 5,4-d{9 PYRIMIDIN-4-ONES
WO2004096757A1 (en) * 2003-04-30 2004-11-11 Novartis Ag Aminopropanol derivatives as sphingosine-1-phosphate receptor modulators
US7060697B2 (en) * 2003-05-19 2006-06-13 Irm Llc Immunosuppressant compounds and compositions
PE20050158A1 (es) * 2003-05-19 2005-05-12 Irm Llc Compuestos inmunosupresores y composiciones
BRPI0615133A2 (pt) * 2005-08-23 2011-05-03 Irm Llc compostos imunossupressores, composições farmacêuticas contendo os mesmos assim como referido uso
US7855193B2 (en) * 2005-11-23 2010-12-21 Epix Pharmaceuticals, Inc. S1P receptor modulating compounds and use thereof
WO2007109334A2 (en) * 2006-03-21 2007-09-27 Epix Delaware, Inc. Sip receptor modulating compounds and use thereof
TW201000099A (en) * 2008-06-20 2010-01-01 Amgen Inc S1P1 receptor agonists and use thereof
EP2318415B1 (en) * 2008-07-15 2013-02-20 Sanofi Oxazolopyrimidines as edg-1 receptor agonists
TWI517851B (zh) * 2010-01-13 2016-01-21 賽諾菲阿凡提斯公司 含２，５，７－經取代唑并嘧啶環之雜環羧酸衍生物
TWI485153B (zh) * 2010-01-13 2015-05-21 Sanofi Aventis ２，５，７－經取代唑并嘧啶衍生物
AR079981A1 (es) * 2010-01-13 2012-03-07 Sanofi Aventis Derivados de acido carboxilico que comprenden un anillo de oxoazolopirimidina 2,5,7- sustituido
AU2011206615B2 (en) * 2010-01-14 2015-03-19 Sanofi Carboxylic acid derivatives having A 2,5-substituted oxazolopyrimidine ring
MY159857A (en) * 2010-01-14 2017-02-15 Sanofi Sa 2,5-substituted oxazolopyrimidine derivatives

Also Published As

Publication number Publication date
US8846690B2 (en) 2014-09-30
ES2437471T3 (es) 2014-01-10
DK2523960T3 (da) 2014-01-20
WO2011086080A1 (de) 2011-07-21
CA2804128A1 (en) 2011-07-21
EP2523960B1 (de) 2013-10-16
BR112012017447B1 (pt) 2019-10-29
HK1178886A1 (en) 2013-09-19
JP5841068B2 (ja) 2016-01-06
KR20120101731A (ko) 2012-09-14
CN102834399B (zh) 2015-04-22
SG182474A1 (en) 2012-08-30
KR101759127B1 (ko) 2017-07-18
BR112012017447A2 (pt) 2016-04-19
CA2804128C (en) 2017-12-12
RU2559896C2 (ru) 2015-08-20
EP2523960A1 (de) 2012-11-21
TW201134474A (en) 2011-10-16
PT2523960E (pt) 2013-12-09
UY33180A (es) 2011-08-31
US20130072502A1 (en) 2013-03-21
AR079884A1 (es) 2012-02-29
JP2013517242A (ja) 2013-05-16
CN102834399A (zh) 2012-12-19
IL220718A (en) 2015-02-26
AU2011206616B2 (en) 2016-06-16
AU2011206616A1 (en) 2012-08-02
TWI482623B (zh) 2015-05-01
MY156476A (en) 2016-02-26
RU2012134548A (ru) 2014-02-20

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