MX2012007837A - Derivados de oxazolopirimidina 2, 5 - sustituidos. - Google Patents
Derivados de oxazolopirimidina 2, 5 - sustituidos.Info
- Publication number
- MX2012007837A MX2012007837A MX2012007837A MX2012007837A MX2012007837A MX 2012007837 A MX2012007837 A MX 2012007837A MX 2012007837 A MX2012007837 A MX 2012007837A MX 2012007837 A MX2012007837 A MX 2012007837A MX 2012007837 A MX2012007837 A MX 2012007837A
- Authority
- MX
- Mexico
- Prior art keywords
- derivatives
- substituted oxazolopyrimidine
- substituted
- oxazolopyrimidine derivatives
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
La presente invención se refiere a compuestos de oxazolopirimidina de fórmula I, (ver fórmula (I)) en la que A, R1 y R2 se definen como se ha indicado en las reivindicaciones. Los compuestos de la fórmula I son adecuados, por ejemplo, para la cicatrización.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10305044 | 2010-01-14 | ||
PCT/EP2011/050303 WO2011086081A1 (de) | 2010-01-14 | 2011-01-12 | 2,5-substituierte oxazolopyrimidinderivate |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2012007837A true MX2012007837A (es) | 2012-07-30 |
Family
ID=41800382
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012007837A MX2012007837A (es) | 2010-01-14 | 2011-01-12 | Derivados de oxazolopirimidina 2, 5 - sustituidos. |
Country Status (21)
Country | Link |
---|---|
US (1) | US9040544B2 (es) |
EP (1) | EP2523963B1 (es) |
JP (1) | JP5841069B2 (es) |
KR (1) | KR101764607B1 (es) |
CN (1) | CN102834400B (es) |
AR (1) | AR079885A1 (es) |
AU (1) | AU2011206617B2 (es) |
BR (1) | BR112012017484A2 (es) |
CA (1) | CA2784565C (es) |
DK (1) | DK2523963T3 (es) |
ES (1) | ES2524712T3 (es) |
HK (1) | HK1178887A1 (es) |
IL (1) | IL220719A (es) |
MX (1) | MX2012007837A (es) |
MY (1) | MY159857A (es) |
PT (1) | PT2523963E (es) |
RU (1) | RU2554874C2 (es) |
SG (1) | SG182483A1 (es) |
TW (1) | TWI544926B (es) |
UY (1) | UY33181A (es) |
WO (1) | WO2011086081A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR079981A1 (es) | 2010-01-13 | 2012-03-07 | Sanofi Aventis | Derivados de acido carboxilico que comprenden un anillo de oxoazolopirimidina 2,5,7- sustituido |
UY33176A (es) | 2010-01-13 | 2011-08-31 | Sanofi Aventis | Derivados de oxazolopirimidina sustituida en 2, 5, 7. |
RU2559896C2 (ru) * | 2010-01-14 | 2015-08-20 | Санофи | Гетероциклические производные карбоновых кислот, имеющие 2,5-замещенное оксазолопиримидиновое кольцо |
CA2784560C (en) * | 2010-01-14 | 2017-12-05 | Sanofi | Carboxylic acid derivatives having a 2,5-substituted oxazolopyrimidine ring |
US9321787B2 (en) | 2011-07-07 | 2016-04-26 | Sanofi | Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3679682A (en) * | 1970-04-23 | 1972-07-25 | Fmc Corp | CERTAIN 5H-ISOXAZOLO{8 5,4-d{9 PYRIMIDIN-4-ONES |
WO2004096813A1 (en) * | 2003-04-25 | 2004-11-11 | University College Cardiff Consultants Limited | Heterocyclic compounds for use in the treatment of viral infections |
JP4638410B2 (ja) * | 2003-04-30 | 2011-02-23 | ノバルティス アーゲー | スフィンゴシン−1−ホスフェートレセプターモジュレーターとしての、アミノプロパノール誘導体 |
CA2524054C (en) * | 2003-05-19 | 2012-04-24 | Irm Llc | Immunosuppressant compounds and compositions |
ES2467160T3 (es) * | 2003-05-19 | 2014-06-12 | Irm Llc | Compuestos y composiciones inmunosupresores |
KR20080047410A (ko) * | 2005-08-23 | 2008-05-28 | 아이알엠 엘엘씨 | 면역억제제 화합물 및 조성물 |
US7919519B2 (en) * | 2005-11-23 | 2011-04-05 | Epix Pharmaceuticals Inc. | S1P receptor modulating compounds and use thereof |
JP2009520688A (ja) | 2005-11-23 | 2009-05-28 | エピックス デラウェア, インコーポレイテッド | S1p受容体調節化合物およびそれらの使用 |
EP2121648A2 (en) * | 2007-03-21 | 2009-11-25 | EPIX Pharmaceuticals, Inc. | S1p receptor modulating compounds and use thereof |
WO2009013545A2 (en) * | 2007-07-26 | 2009-01-29 | Astrazeneca Ab | Chemical compounds |
US7863291B2 (en) * | 2008-04-23 | 2011-01-04 | Bristol-Myers Squibb Company | Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands |
TW201000099A (en) | 2008-06-20 | 2010-01-01 | Amgen Inc | S1P1 receptor agonists and use thereof |
RU2503680C2 (ru) * | 2008-07-15 | 2014-01-10 | Санофи-Авентис | ОКСАЗОЛОПИРИМИДИНЫ КАК АГОНИСТЫ РЕЦЕПТОРА Edg-1 |
UY33176A (es) | 2010-01-13 | 2011-08-31 | Sanofi Aventis | Derivados de oxazolopirimidina sustituida en 2, 5, 7. |
AR079982A1 (es) * | 2010-01-13 | 2012-03-07 | Sanofi Aventis | Derivados de acido carboxilico heterociclicos que comprenden un anillo de oxazolopirimidina 2,5,7- sustituido., composiciones farmaceuticas y procesos para prepararlos. |
AR079981A1 (es) * | 2010-01-13 | 2012-03-07 | Sanofi Aventis | Derivados de acido carboxilico que comprenden un anillo de oxoazolopirimidina 2,5,7- sustituido |
RU2559896C2 (ru) | 2010-01-14 | 2015-08-20 | Санофи | Гетероциклические производные карбоновых кислот, имеющие 2,5-замещенное оксазолопиримидиновое кольцо |
CA2784560C (en) * | 2010-01-14 | 2017-12-05 | Sanofi | Carboxylic acid derivatives having a 2,5-substituted oxazolopyrimidine ring |
-
2011
- 2011-01-12 TW TW100101051A patent/TWI544926B/zh not_active IP Right Cessation
- 2011-01-12 WO PCT/EP2011/050303 patent/WO2011086081A1/de active Application Filing
- 2011-01-12 DK DK11700529.8T patent/DK2523963T3/en active
- 2011-01-12 CN CN201180014162.5A patent/CN102834400B/zh active Active
- 2011-01-12 EP EP11700529.8A patent/EP2523963B1/de active Active
- 2011-01-12 UY UY0001033181A patent/UY33181A/es not_active Application Discontinuation
- 2011-01-12 AR ARP110100094A patent/AR079885A1/es active IP Right Grant
- 2011-01-12 RU RU2012134636/04A patent/RU2554874C2/ru active
- 2011-01-12 AU AU2011206617A patent/AU2011206617B2/en not_active Ceased
- 2011-01-12 BR BR112012017484-3A patent/BR112012017484A2/pt active Search and Examination
- 2011-01-12 SG SG2012051397A patent/SG182483A1/en unknown
- 2011-01-12 PT PT117005298T patent/PT2523963E/pt unknown
- 2011-01-12 KR KR1020127021237A patent/KR101764607B1/ko active IP Right Grant
- 2011-01-12 JP JP2012548412A patent/JP5841069B2/ja active Active
- 2011-01-12 CA CA2784565A patent/CA2784565C/en not_active Expired - Fee Related
- 2011-01-12 ES ES11700529.8T patent/ES2524712T3/es active Active
- 2011-01-12 MY MYPI2012002622A patent/MY159857A/en unknown
- 2011-01-12 MX MX2012007837A patent/MX2012007837A/es active IP Right Grant
- 2011-01-14 US US13/521,825 patent/US9040544B2/en active Active
-
2012
- 2012-07-02 IL IL220719A patent/IL220719A/en active IP Right Grant
-
2013
- 2013-05-10 HK HK13105593.5A patent/HK1178887A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CN102834400A (zh) | 2012-12-19 |
AU2011206617B2 (en) | 2015-07-16 |
EP2523963B1 (de) | 2014-08-27 |
PT2523963E (pt) | 2014-11-06 |
TWI544926B (zh) | 2016-08-11 |
BR112012017484A2 (pt) | 2020-08-25 |
JP5841069B2 (ja) | 2016-01-06 |
SG182483A1 (en) | 2012-08-30 |
HK1178887A1 (en) | 2013-09-19 |
AR079885A1 (es) | 2012-02-29 |
IL220719A (en) | 2015-03-31 |
MY159857A (en) | 2017-02-15 |
US20130072501A1 (en) | 2013-03-21 |
ES2524712T3 (es) | 2014-12-11 |
KR20120115403A (ko) | 2012-10-17 |
CA2784565C (en) | 2018-03-13 |
CA2784565A1 (en) | 2011-07-21 |
TW201134473A (en) | 2011-10-16 |
KR101764607B1 (ko) | 2017-08-03 |
RU2554874C2 (ru) | 2015-06-27 |
JP2013517243A (ja) | 2013-05-16 |
RU2012134636A (ru) | 2014-02-20 |
US9040544B2 (en) | 2015-05-26 |
AU2011206617A1 (en) | 2012-08-02 |
DK2523963T3 (en) | 2014-12-01 |
CN102834400B (zh) | 2015-06-10 |
EP2523963A1 (de) | 2012-11-21 |
WO2011086081A1 (de) | 2011-07-21 |
UY33181A (es) | 2011-08-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |