UY33178A - Derivados de ácido carboxílico heteroxíclicos que comprenden un anillo de oxazolopirimidina 2, 5, 7-sustituido - Google Patents

Derivados de ácido carboxílico heteroxíclicos que comprenden un anillo de oxazolopirimidina 2, 5, 7-sustituido

Info

Publication number
UY33178A
UY33178A UY0001033178A UY33178A UY33178A UY 33178 A UY33178 A UY 33178A UY 0001033178 A UY0001033178 A UY 0001033178A UY 33178 A UY33178 A UY 33178A UY 33178 A UY33178 A UY 33178A
Authority
UY
Uruguay
Prior art keywords
carboxylic acid
ring
acid derivatives
oxazolopirimidine
heteroxyclic
Prior art date
Application number
UY0001033178A
Other languages
English (en)
Inventor
Dr Axel Diertrich
Dr Andreas Gille
Dr Stephanie Hechtel
Dr Katrin Hiss
Dr Thmas Huebschle
Dr Dieter Kadereit
Dr Matthias Schaefer
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of UY33178A publication Critical patent/UY33178A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Derivados de ácido carboxílico heteroxíclicos que comprenden un anillo oxazolopirimidina 2,5,7-sustituido. La presente invención se refiere a compuestos de oxazolopirimidina de fórmula I, en la qe A, R1, R2, R3, R4, X e Y se definen como se ha indicado en las reivindicaciones. Los compuestos de fórmula I son adecuados, p. ej., para la curación de heridas.
UY0001033178A 2010-01-13 2011-01-11 Derivados de ácido carboxílico heteroxíclicos que comprenden un anillo de oxazolopirimidina 2, 5, 7-sustituido UY33178A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10305037 2010-01-13

Publications (1)

Publication Number Publication Date
UY33178A true UY33178A (es) 2011-08-31

Family

ID=41820658

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001033178A UY33178A (es) 2010-01-13 2011-01-11 Derivados de ácido carboxílico heteroxíclicos que comprenden un anillo de oxazolopirimidina 2, 5, 7-sustituido

Country Status (21)

Country Link
US (1) US8846691B2 (es)
EP (1) EP2523959B1 (es)
JP (1) JP5844278B2 (es)
KR (1) KR101759121B1 (es)
CN (1) CN102906098B (es)
AR (1) AR079982A1 (es)
AU (1) AU2011206614B8 (es)
BR (1) BR112012017240A2 (es)
CA (1) CA2792134C (es)
DK (1) DK2523959T3 (es)
ES (1) ES2449705T3 (es)
HK (1) HK1178888A1 (es)
IL (1) IL220708A (es)
MX (1) MX2012007833A (es)
MY (1) MY156551A (es)
PT (1) PT2523959E (es)
RU (1) RU2554869C2 (es)
SG (1) SG182473A1 (es)
TW (1) TWI517851B (es)
UY (1) UY33178A (es)
WO (1) WO2011086078A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI485153B (zh) 2010-01-13 2015-05-21 Sanofi Aventis ２，５，７－經取代唑并嘧啶衍生物
AU2011206615B2 (en) * 2010-01-14 2015-03-19 Sanofi Carboxylic acid derivatives having A 2,5-substituted oxazolopyrimidine ring
CN102834399B (zh) * 2010-01-14 2015-04-22 赛诺菲 具有2,5-取代的*唑并嘧啶环的杂环羧酸衍生物
MY159857A (en) 2010-01-14 2017-02-15 Sanofi Sa 2,5-substituted oxazolopyrimidine derivatives
US9321787B2 (en) 2011-07-07 2016-04-26 Sanofi Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3679682A (en) * 1970-04-23 1972-07-25 Fmc Corp CERTAIN 5H-ISOXAZOLO{8 5,4-d{9 PYRIMIDIN-4-ONES
PE20050158A1 (es) * 2003-05-19 2005-05-12 Irm Llc Compuestos inmunosupresores y composiciones
US7060697B2 (en) * 2003-05-19 2006-06-13 Irm Llc Immunosuppressant compounds and compositions
US7855193B2 (en) * 2005-11-23 2010-12-21 Epix Pharmaceuticals, Inc. S1P receptor modulating compounds and use thereof
WO2007109334A2 (en) * 2006-03-21 2007-09-27 Epix Delaware, Inc. Sip receptor modulating compounds and use thereof
TW201000099A (en) * 2008-06-20 2010-01-01 Amgen Inc S1P1 receptor agonists and use thereof

Also Published As

Publication number Publication date
KR20120101593A (ko) 2012-09-13
TW201134472A (en) 2011-10-16
ES2449705T3 (es) 2014-03-20
AR079982A1 (es) 2012-03-07
AU2011206614A1 (en) 2012-08-02
PT2523959E (pt) 2014-03-10
CN102906098B (zh) 2015-07-15
JP5844278B2 (ja) 2016-01-13
AU2011206614B2 (en) 2015-02-26
CA2792134C (en) 2017-12-05
EP2523959A1 (de) 2012-11-21
RU2012134463A (ru) 2014-02-20
CN102906098A (zh) 2013-01-30
KR101759121B1 (ko) 2017-07-18
MY156551A (en) 2016-02-26
AU2011206614B8 (en) 2015-03-05
MX2012007833A (es) 2012-07-20
TWI517851B (zh) 2016-01-21
WO2011086078A1 (de) 2011-07-21
HK1178888A1 (en) 2013-09-19
SG182473A1 (en) 2012-08-30
CA2792134A1 (en) 2011-07-21
US20130158051A1 (en) 2013-06-20
RU2554869C2 (ru) 2015-06-27
IL220708A (en) 2015-02-26
EP2523959B1 (de) 2013-11-27
BR112012017240A2 (pt) 2016-03-22
US8846691B2 (en) 2014-09-30
DK2523959T3 (en) 2014-03-10
JP2013517240A (ja) 2013-05-16

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20140610