PT2523959E - Derivados heterocíclicos de ácidos carboxílicos com um anel oxazolopirimidina substituído em 2,5,7 - Google Patents

Derivados heterocíclicos de ácidos carboxílicos com um anel oxazolopirimidina substituído em 2,5,7 Download PDF

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Publication number
PT2523959E
PT2523959E PT117001362T PT11700136T PT2523959E PT 2523959 E PT2523959 E PT 2523959E PT 117001362 T PT117001362 T PT 117001362T PT 11700136 T PT11700136 T PT 11700136T PT 2523959 E PT2523959 E PT 2523959E
Authority
PT
Portugal
Prior art keywords
carboxylic acid
acid derivatives
heterocyclic carboxylic
oxazolopyrimidine ring
substituted oxazolopyrimidine
Prior art date
Application number
PT117001362T
Other languages
English (en)
Inventor
Stephanie Hachtel
Dieter Kadereit
Matthias Schaefer
Axel Dietrich
Thomas Huebschle
Katrin Hiss
Andreas Gille
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of PT2523959E publication Critical patent/PT2523959E/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT117001362T 2010-01-13 2011-01-12 Derivados heterocíclicos de ácidos carboxílicos com um anel oxazolopirimidina substituído em 2,5,7 PT2523959E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10305037 2010-01-13

Publications (1)

Publication Number Publication Date
PT2523959E true PT2523959E (pt) 2014-03-10

Family

ID=41820658

Family Applications (1)

Application Number Title Priority Date Filing Date
PT117001362T PT2523959E (pt) 2010-01-13 2011-01-12 Derivados heterocíclicos de ácidos carboxílicos com um anel oxazolopirimidina substituído em 2,5,7

Country Status (21)

Country Link
US (1) US8846691B2 (pt)
EP (1) EP2523959B1 (pt)
JP (1) JP5844278B2 (pt)
KR (1) KR101759121B1 (pt)
CN (1) CN102906098B (pt)
AR (1) AR079982A1 (pt)
AU (1) AU2011206614B8 (pt)
BR (1) BR112012017240A2 (pt)
CA (1) CA2792134C (pt)
DK (1) DK2523959T3 (pt)
ES (1) ES2449705T3 (pt)
HK (1) HK1178888A1 (pt)
IL (1) IL220708A (pt)
MX (1) MX2012007833A (pt)
MY (1) MY156551A (pt)
PT (1) PT2523959E (pt)
RU (1) RU2554869C2 (pt)
SG (1) SG182473A1 (pt)
TW (1) TWI517851B (pt)
UY (1) UY33178A (pt)
WO (1) WO2011086078A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI485153B (zh) 2010-01-13 2015-05-21 Sanofi Aventis 2,5,7-經取代唑并嘧啶衍生物
AU2011206615B2 (en) * 2010-01-14 2015-03-19 Sanofi Carboxylic acid derivatives having A 2,5-substituted oxazolopyrimidine ring
CN102834399B (zh) * 2010-01-14 2015-04-22 赛诺菲 具有2,5-取代的*唑并嘧啶环的杂环羧酸衍生物
MY159857A (en) 2010-01-14 2017-02-15 Sanofi Sa 2,5-substituted oxazolopyrimidine derivatives
US9321787B2 (en) 2011-07-07 2016-04-26 Sanofi Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3679682A (en) * 1970-04-23 1972-07-25 Fmc Corp CERTAIN 5H-ISOXAZOLO{8 5,4-d{9 PYRIMIDIN-4-ONES
PE20050158A1 (es) * 2003-05-19 2005-05-12 Irm Llc Compuestos inmunosupresores y composiciones
US7060697B2 (en) * 2003-05-19 2006-06-13 Irm Llc Immunosuppressant compounds and compositions
US7855193B2 (en) * 2005-11-23 2010-12-21 Epix Pharmaceuticals, Inc. S1P receptor modulating compounds and use thereof
WO2007109334A2 (en) * 2006-03-21 2007-09-27 Epix Delaware, Inc. Sip receptor modulating compounds and use thereof
TW201000099A (en) * 2008-06-20 2010-01-01 Amgen Inc S1P1 receptor agonists and use thereof

Also Published As

Publication number Publication date
KR20120101593A (ko) 2012-09-13
TW201134472A (en) 2011-10-16
ES2449705T3 (es) 2014-03-20
AR079982A1 (es) 2012-03-07
AU2011206614A1 (en) 2012-08-02
CN102906098B (zh) 2015-07-15
UY33178A (es) 2011-08-31
JP5844278B2 (ja) 2016-01-13
AU2011206614B2 (en) 2015-02-26
CA2792134C (en) 2017-12-05
EP2523959A1 (de) 2012-11-21
RU2012134463A (ru) 2014-02-20
CN102906098A (zh) 2013-01-30
KR101759121B1 (ko) 2017-07-18
MY156551A (en) 2016-02-26
AU2011206614B8 (en) 2015-03-05
MX2012007833A (es) 2012-07-20
TWI517851B (zh) 2016-01-21
WO2011086078A1 (de) 2011-07-21
HK1178888A1 (en) 2013-09-19
SG182473A1 (en) 2012-08-30
CA2792134A1 (en) 2011-07-21
US20130158051A1 (en) 2013-06-20
RU2554869C2 (ru) 2015-06-27
IL220708A (en) 2015-02-26
EP2523959B1 (de) 2013-11-27
BR112012017240A2 (pt) 2016-03-22
US8846691B2 (en) 2014-09-30
DK2523959T3 (en) 2014-03-10
JP2013517240A (ja) 2013-05-16

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