CO6612239A2 - Derivados de ácido carboxílico que comprenden un anillo de oxazolopiridina 2,5-sustituido - Google Patents

Derivados de ácido carboxílico que comprenden un anillo de oxazolopiridina 2,5-sustituido

Info

Publication number
CO6612239A2
CO6612239A2 CO12125684A CO12125684A CO6612239A2 CO 6612239 A2 CO6612239 A2 CO 6612239A2 CO 12125684 A CO12125684 A CO 12125684A CO 12125684 A CO12125684 A CO 12125684A CO 6612239 A2 CO6612239 A2 CO 6612239A2
Authority
CO
Colombia
Prior art keywords
substituted
carboxylic acid
acid derivatives
oxazolopyridine ring
oxazolopyridine
Prior art date
Application number
CO12125684A
Other languages
English (en)
Inventor
Dieter Kadereit
Matthias Schaefer
Stephanie Hachtel
Axel Dietrich
Thomas Huebschle
Katrin Hiss
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of CO6612239A2 publication Critical patent/CO6612239A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a compuestos de oxazolopirimidina de la fórmula I,en la que A, R, R, Ry X se definen como se ha indicado en las reivindicaciones. Los compuestos de la fórmula I son adecuados, p. ej., para la curación de heridas.
CO12125684A 2010-01-14 2012-07-26 Derivados de ácido carboxílico que comprenden un anillo de oxazolopiridina 2,5-sustituido CO6612239A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10305042 2010-01-14

Publications (1)

Publication Number Publication Date
CO6612239A2 true CO6612239A2 (es) 2013-02-01

Family

ID=41800578

Family Applications (1)

Application Number Title Priority Date Filing Date
CO12125684A CO6612239A2 (es) 2010-01-14 2012-07-26 Derivados de ácido carboxílico que comprenden un anillo de oxazolopiridina 2,5-sustituido

Country Status (31)

Country Link
US (1) US8846692B2 (es)
EP (1) EP2523962B1 (es)
JP (1) JP5841067B2 (es)
KR (1) KR101759128B1 (es)
CN (1) CN102791717B (es)
AR (1) AR079997A1 (es)
AU (1) AU2011206615B2 (es)
BR (1) BR112012017437B1 (es)
CA (1) CA2784560C (es)
CL (1) CL2012001972A1 (es)
CO (1) CO6612239A2 (es)
CY (1) CY1115055T1 (es)
DK (1) DK2523962T3 (es)
ES (1) ES2441954T3 (es)
HK (1) HK1178885A1 (es)
HR (1) HRP20140179T1 (es)
IL (1) IL220720A (es)
MA (1) MA33917B1 (es)
MX (1) MX2012007834A (es)
MY (1) MY156550A (es)
NZ (1) NZ601113A (es)
PL (1) PL2523962T3 (es)
PT (1) PT2523962E (es)
RS (1) RS53254B (es)
RU (1) RU2564018C2 (es)
SG (1) SG182484A1 (es)
SI (1) SI2523962T1 (es)
TW (1) TWI510242B (es)
UY (1) UY33179A (es)
WO (1) WO2011086079A1 (es)
ZA (1) ZA201204174B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR079980A1 (es) 2010-01-13 2012-03-07 Sanofi Aventis Derivados de oxazolopirimidina sustituida en 2,5,7
UY33177A (es) 2010-01-13 2011-08-31 Sanofi Aventis Derivados de ácido carboxílico que comprenden un anillo de oxazolopirimidina 2, 5, 7-sustituido
SG182474A1 (en) * 2010-01-14 2012-08-30 Sanofi Sa Heterocyclic carboxylic acid derivatives having a 2,5-substituted oxazolopyrimidine ring
EP2523963B1 (de) 2010-01-14 2014-08-27 Sanofi 2,5-substituierte oxazolopyrimidinderivate als edg-1 agonisten
US9321787B2 (en) * 2011-07-07 2016-04-26 Sanofi Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring
EP2862574A1 (en) * 2013-10-15 2015-04-22 Sanofi {4-[5-(3-chloro-phenoxy)-oxazolo[5,4 d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-acetic acid for use in the prevention or treatment of acute kidney injury

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3679682A (en) * 1970-04-23 1972-07-25 Fmc Corp CERTAIN 5H-ISOXAZOLO{8 5,4-d{9 PYRIMIDIN-4-ONES
JPH01242587A (ja) * 1988-03-25 1989-09-27 Sankyo Co Ltd 縮環オキサゾロチエノピリミジン誘導体
EP1622913A1 (en) * 2003-04-25 2006-02-08 University College Cardiff Consultants, Ltd. Heterocyclic compounds for use in the treatment of viral infections
WO2004096757A1 (en) * 2003-04-30 2004-11-11 Novartis Ag Aminopropanol derivatives as sphingosine-1-phosphate receptor modulators
CL2004001120A1 (es) * 2003-05-19 2005-04-15 Irm Llc Compuestos derivados de amina sustituidas con heterociclos, inmunosupresores; composicion farmaceutica; y uso para tratar enfermedades mediadas por interacciones de linfocito, tales como enfermedades autoinmunes, inflamatorias, infecciosas, cancer.
SI1638551T1 (sl) * 2003-05-19 2012-04-30 Irm Llc Imunosupresivne spojine in sestavki
CA2619101A1 (en) * 2005-08-23 2007-03-01 Irm Llc Immunosuppressant compounds and compositions
AU2007227278B2 (en) * 2007-03-21 2014-09-11 Epix Pharmaceuticals, Inc. SIP receptor modulating compounds and use thereof
TW201000099A (en) * 2008-06-20 2010-01-01 Amgen Inc S1P1 receptor agonists and use thereof
CA2730843A1 (en) * 2008-07-15 2010-01-21 Sanofi-Aventis Oxazolopyrimidines as edg-1 receptor agonists
AR079980A1 (es) * 2010-01-13 2012-03-07 Sanofi Aventis Derivados de oxazolopirimidina sustituida en 2,5,7
UY33177A (es) * 2010-01-13 2011-08-31 Sanofi Aventis Derivados de ácido carboxílico que comprenden un anillo de oxazolopirimidina 2, 5, 7-sustituido
UY33178A (es) * 2010-01-13 2011-08-31 Sanofi Aventis Derivados de ácido carboxílico heteroxíclicos que comprenden un anillo de oxazolopirimidina 2, 5, 7-sustituido
EP2523963B1 (de) * 2010-01-14 2014-08-27 Sanofi 2,5-substituierte oxazolopyrimidinderivate als edg-1 agonisten
SG182474A1 (en) * 2010-01-14 2012-08-30 Sanofi Sa Heterocyclic carboxylic acid derivatives having a 2,5-substituted oxazolopyrimidine ring

Also Published As

Publication number Publication date
NZ601113A (en) 2013-07-26
SI2523962T1 (sl) 2014-02-28
AU2011206615A1 (en) 2012-08-02
RU2564018C2 (ru) 2015-09-27
PT2523962E (pt) 2014-02-06
AR079997A1 (es) 2012-03-07
IL220720A (en) 2015-02-26
MX2012007834A (es) 2012-07-30
KR20120101732A (ko) 2012-09-14
HK1178885A1 (en) 2013-09-19
WO2011086079A1 (de) 2011-07-21
PL2523962T3 (pl) 2014-05-30
JP5841067B2 (ja) 2016-01-06
UY33179A (es) 2011-08-31
CY1115055T1 (el) 2016-12-14
TW201134475A (en) 2011-10-16
US8846692B2 (en) 2014-09-30
CN102791717A (zh) 2012-11-21
EP2523962B1 (de) 2013-11-27
RS53254B (en) 2014-08-29
CN102791717B (zh) 2016-03-30
CA2784560C (en) 2017-12-05
MA33917B1 (fr) 2013-01-02
TWI510242B (zh) 2015-12-01
BR112012017437A2 (pt) 2021-03-02
EP2523962A1 (de) 2012-11-21
AU2011206615B2 (en) 2015-03-19
HRP20140179T1 (hr) 2014-03-28
US20130079358A1 (en) 2013-03-28
KR101759128B1 (ko) 2017-07-18
ZA201204174B (en) 2013-02-27
ES2441954T3 (es) 2014-02-07
CA2784560A1 (en) 2011-07-21
DK2523962T3 (en) 2014-03-10
MY156550A (en) 2016-02-26
CL2012001972A1 (es) 2012-10-19
RU2012134630A (ru) 2014-02-20
SG182484A1 (en) 2012-08-30
BR112012017437B1 (pt) 2022-03-03
IL220720A0 (en) 2012-08-30
JP2013517241A (ja) 2013-05-16

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