CY1112505T1 - Ανοσοκατασταλτικες ενωσεις και συνθεσεις - Google Patents

Ανοσοκατασταλτικες ενωσεις και συνθεσεις

Info

Publication number
CY1112505T1
CY1112505T1 CY20121100286T CY121100286T CY1112505T1 CY 1112505 T1 CY1112505 T1 CY 1112505T1 CY 20121100286 T CY20121100286 T CY 20121100286T CY 121100286 T CY121100286 T CY 121100286T CY 1112505 T1 CY1112505 T1 CY 1112505T1
Authority
CY
Cyprus
Prior art keywords
compositions
immunosuppressive compounds
diseases
immunosuppressant
prevention
Prior art date
Application number
CY20121100286T
Other languages
English (en)
Inventor
Thomas H Marsilje
Nathanael S Gray
Tao Jiang
Wenshuo Lu
Shifeng Pan
Original Assignee
Irm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Irm Llc filed Critical Irm Llc
Publication of CY1112505T1 publication Critical patent/CY1112505T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Abstract

Η παρούσα εφεύρεση σχετίζεται με ανοσοκατασταλτικά, τη διαδικασία για την παρασκευή τους, τις χρήσεις τους και τις φαρμακευτικές συνθέσεις που τα περιέχουν. Η εφεύρεση παρέχει μια νέα κατηγορία ενώσεων χρήσιμων στη θεραπεία ή στην πρόληψη ασθενειών ή διαταραχών που προκαλούνται από λεμφικές αλληλεπιδράσεις, συγκεκριμένα ασθένειες οι οποίες σχετίζονται με τη μεταγωγή σήματος μέσω του υποδοχέα ΕDG.
CY20121100286T 2003-05-19 2012-03-16 Ανοσοκατασταλτικες ενωσεις και συνθεσεις CY1112505T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47193103P 2003-05-19 2003-05-19
EP04752678A EP1638551B1 (en) 2003-05-19 2004-05-19 Immunosuppressant compounds and compositions

Publications (1)

Publication Number Publication Date
CY1112505T1 true CY1112505T1 (el) 2015-12-09

Family

ID=33476902

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20121100286T CY1112505T1 (el) 2003-05-19 2012-03-16 Ανοσοκατασταλτικες ενωσεις και συνθεσεις

Country Status (18)

Country Link
US (2) US7462629B2 (el)
EP (1) EP1638551B1 (el)
JP (1) JP4575920B2 (el)
CN (4) CN1791395B (el)
AT (1) ATE537825T1 (el)
AU (2) AU2004240649A1 (el)
BR (1) BRPI0410454A (el)
CA (1) CA2524054C (el)
CY (1) CY1112505T1 (el)
DK (1) DK1638551T3 (el)
ES (1) ES2379169T3 (el)
HK (1) HK1090559A1 (el)
MX (1) MXPA05012459A (el)
PL (1) PL1638551T3 (el)
PT (1) PT1638551E (el)
SI (1) SI1638551T1 (el)
WO (1) WO2004103309A2 (el)
ZA (1) ZA200508203B (el)

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US7462629B2 (en) 2008-12-09
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MXPA05012459A (es) 2006-02-22
CN1787817A (zh) 2006-06-14
EP1638551A2 (en) 2006-03-29
CA2524054A1 (en) 2004-12-02
US7060697B2 (en) 2006-06-13
CN1791395A (zh) 2006-06-21
EP1638551A4 (en) 2008-12-31
CN1791592B (zh) 2012-07-04
HK1090559A1 (en) 2006-12-29
AU2004240649A1 (en) 2004-12-02
SI1638551T1 (sl) 2012-04-30
CN1816544A (zh) 2006-08-09
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CN1791592A (zh) 2006-06-21
PL1638551T3 (pl) 2012-05-31
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US20050009786A1 (en) 2005-01-13
CN1787817B (zh) 2011-09-07
US20050014724A1 (en) 2005-01-20
DK1638551T3 (da) 2012-04-02
JP4575920B2 (ja) 2010-11-04
EP1638551B1 (en) 2011-12-21
ATE537825T1 (de) 2012-01-15
AU2008203088A1 (en) 2008-08-07
CN1816544B (zh) 2011-06-08
BRPI0410454A (pt) 2006-06-13
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ZA200508203B (en) 2007-02-28
PT1638551E (pt) 2012-03-28

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