CY1110494T1 - Μεταστροφες μεταβολικου ρυθμου σε ζυμωσεις που εκφραζουν ανασυνδυασμενες πρωτεϊνες - Google Patents

Μεταστροφες μεταβολικου ρυθμου σε ζυμωσεις που εκφραζουν ανασυνδυασμενες πρωτεϊνες

Info

Publication number
CY1110494T1
CY1110494T1 CY20091100652T CY091100652T CY1110494T1 CY 1110494 T1 CY1110494 T1 CY 1110494T1 CY 20091100652 T CY20091100652 T CY 20091100652T CY 091100652 T CY091100652 T CY 091100652T CY 1110494 T1 CY1110494 T1 CY 1110494T1
Authority
CY
Cyprus
Prior art keywords
expression
host cells
recombinant host
knowledges
transformation
Prior art date
Application number
CY20091100652T
Other languages
Greek (el)
English (en)
Inventor
Dana Andersen
John Joly
Bradley R Snedecor
Original Assignee
Genentech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22928808&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1110494(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech, Inc. filed Critical Genentech, Inc.
Publication of CY1110494T1 publication Critical patent/CY1110494T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Fertilizers (AREA)
CY20091100652T 2000-11-03 2009-06-23 Μεταστροφες μεταβολικου ρυθμου σε ζυμωσεις που εκφραζουν ανασυνδυασμενες πρωτεϊνες CY1110494T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24596200P 2000-11-03 2000-11-03
EP01987201A EP1332222B1 (en) 2000-11-03 2001-11-01 Metabolic rate shifts in fermentations expressing recombinant proteins

Publications (1)

Publication Number Publication Date
CY1110494T1 true CY1110494T1 (el) 2015-04-29

Family

ID=22928808

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100652T CY1110494T1 (el) 2000-11-03 2009-06-23 Μεταστροφες μεταβολικου ρυθμου σε ζυμωσεις που εκφραζουν ανασυνδυασμενες πρωτεϊνες

Country Status (14)

Country Link
US (1) US6716602B2 (xx)
EP (1) EP1332222B1 (xx)
JP (1) JP4878724B2 (xx)
AT (1) ATE426674T1 (xx)
AU (1) AU3944002A (xx)
CA (1) CA2426100A1 (xx)
CY (1) CY1110494T1 (xx)
DE (1) DE60138127D1 (xx)
DK (1) DK1332222T3 (xx)
ES (1) ES2324645T3 (xx)
HK (1) HK1054765A1 (xx)
IL (2) IL155482A0 (xx)
PT (1) PT1332222E (xx)
WO (1) WO2002040697A2 (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7294481B1 (en) 1999-01-05 2007-11-13 Immunex Corporation Method for producing recombinant proteins
AU2003243366B2 (en) * 2002-05-30 2008-01-24 Natureworks Llc Methods and materials for the production of lactic acid in yeast
GB0321100D0 (en) * 2003-09-09 2003-10-08 Celltech R&D Ltd Biological products
WO2010031074A2 (en) 2008-09-15 2010-03-18 Genentech, Inc. Compositions and methods for regulating cell osmolarity
AU2010311567B2 (en) 2009-10-26 2015-03-26 Chugai Seiyaku Kabushiki Kaisha Method for the production of a glycosylated immunoglobulin
GB2482536B (en) * 2010-08-05 2013-07-24 Hera Pharmaceuticals Inc Expression of antibody or a fragment thereof in lactobacillus
CN112575018A (zh) 2012-09-19 2021-03-30 弗·哈夫曼-拉罗切有限公司 用于防止正亮氨酸错误地掺入蛋白质中的方法和组合物
ES2704697T3 (es) 2013-08-05 2019-03-19 Greenlight Biosciences Inc Proteínas genomodificadas con un sitio de escisión de proteasa
EP3147369A4 (en) 2014-05-21 2018-02-07 Ajinomoto Co., Inc. Fibroin-like protein production method
CN104164465B (zh) * 2014-07-14 2017-07-04 北京泰德制药股份有限公司 一种表达重组蛋白的发酵工艺
RU2739500C2 (ru) 2014-11-05 2020-12-25 Дженентек, Инк. Способы получения двуцепочечных белков в бактериях
CN108064308B (zh) * 2014-11-05 2023-06-09 豪夫迈·罗氏有限公司 细菌中产生双链蛋白的方法
JP2018516600A (ja) 2015-05-29 2018-06-28 カーギル・インコーポレイテッド 高いｐＨを使用してステビオールグリコシドを産生するための発酵方法及びそこから得られる組成物
CN107614677A (zh) 2015-05-29 2018-01-19 嘉吉公司 用于使用多阶段进料生产甜菊醇糖苷的发酵方法
WO2016196345A1 (en) 2015-05-29 2016-12-08 Cargill, Incorporated Heat treatment to produce glycosides
CN107920548A (zh) 2015-08-06 2018-04-17 嘉吉公司 用于产生甜菊醇糖苷的发酵方法
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
US11098310B2 (en) 2016-01-27 2021-08-24 Just-Evotec Biologics, Inc. Expression from transposon-based vectors and uses
JP6937309B2 (ja) 2016-01-27 2021-09-22 ジャスト−エヴォテック バイオロジックス、インコーポレイテッド ハイブリッドプロモーターおよびその使用
US11261462B2 (en) 2016-01-27 2022-03-01 Just-Evotec Biologics, Inc. Inducible expression from transposon-based vectors and uses
AR111625A1 (es) 2017-04-27 2019-07-31 Juno Therapeutics Gmbh Reactivos de partículas oligoméricas y métodos de uso de los mismos

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4565785A (en) 1978-06-08 1986-01-21 The President And Fellows Of Harvard College Recombinant DNA molecule
US4673641A (en) 1982-12-16 1987-06-16 Molecular Genetics Research And Development Limited Partnership Co-aggregate purification of proteins
US4710473A (en) 1983-08-10 1987-12-01 Amgen, Inc. DNA plasmids
US4738921A (en) 1984-09-27 1988-04-19 Eli Lilly And Company Derivative of the tryptophan operon for expression of fused gene products
US4795706A (en) 1985-01-31 1989-01-03 Eli Lilly And Company Novel expression control sequences
US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
US5342763A (en) 1992-11-23 1994-08-30 Genentech, Inc. Method for producing polypeptide via bacterial fermentation
CA2153445C (en) * 1994-09-08 2002-05-21 Ashok Raj Saxena Video optimized media streamer user interface
US5639635A (en) 1994-11-03 1997-06-17 Genentech, Inc. Process for bacterial production of polypeptides
US5789199A (en) * 1994-11-03 1998-08-04 Genentech, Inc. Process for bacterial production of polypeptides
US5790423A (en) * 1995-06-14 1998-08-04 Audible, Inc. Interactive audio transmission receiving and playback system
AR005035A1 (es) 1995-12-11 1999-04-07 Merck Patent Ges Mit Beschränkter Haftung Procedimiento para preparar proteinas recombinantes en e. coli, mediante fermentacion con gran concentracion de celulas.
US6615192B1 (en) * 1999-03-12 2003-09-02 Matsushita Electric Industrial Co., Ltd. Contents copying system, copying method, computer-readable recording medium and disc drive copying contents but not a cipher key via a host computer
CA2338634C (en) * 1999-05-28 2007-06-26 Matsushita Electric Industrial Co., Ltd. A semiconductor memory card, playback apparatus, recording apparatus, playback method, recording method, and computer-readable recording medium
DE19943919B4 (de) 1999-09-14 2004-05-27 Pharmacia Ab Verfahren zur Steigerung der Ausbeute von rekombinanten Proteinen in mikrobiellen Fermentationsprozessen

Also Published As

Publication number Publication date
CA2426100A1 (en) 2002-05-23
US6716602B2 (en) 2004-04-06
US20020164700A1 (en) 2002-11-07
EP1332222B1 (en) 2009-03-25
PT1332222E (pt) 2009-06-30
AU3944002A (en) 2002-05-27
DE60138127D1 (de) 2009-05-07
DK1332222T3 (da) 2009-07-06
WO2002040697A2 (en) 2002-05-23
IL155482A (en) 2010-12-30
EP1332222A2 (en) 2003-08-06
HK1054765A1 (en) 2003-12-12
ATE426674T1 (de) 2009-04-15
JP2004517614A (ja) 2004-06-17
JP4878724B2 (ja) 2012-02-15
IL155482A0 (en) 2003-11-23
WO2002040697A3 (en) 2003-03-13
ES2324645T3 (es) 2009-08-12

Similar Documents

Publication Publication Date Title
CY1110494T1 (el) Μεταστροφες μεταβολικου ρυθμου σε ζυμωσεις που εκφραζουν ανασυνδυασμενες πρωτεϊνες
DE69332981D1 (de) Methoden zur herstellung löslicher, oligomerer proteine
DK0663010T3 (da) Fremgangsmåde til forøgelse af sekretion af overudtrykte proteiner
BR0306979A (pt) Polipeptìdeo isolado, proteìna de fusão, molécula isolada de polinucleotìdeo, vetor de expressão, célula cultivada, anticorpo ou fragmento de anticorpo, e, métodos para produzir uma proteìna, para produzir um anticorpo, para estimular uma resposta imune em um mamìfero, para expandir células hematopoiéticas e progenitores de células hematopoiéticas, para detectar a presença de rna zcytor17lig e de zcytor17lig em uma amostra biológica, para matar cérlulas cancerìgenas, para inibir a proliferação induzida por zcytor17lig ou diferenciação de células hematopoiéticas e progenitoras de células hematopoiéticas, para reduzir a inflamação induzida por zcytor17lig para suprimir uma resposta inflamatória em um mamìfero com inflamação, para tratar um mamìfero acometido por uma doença inflamatória e para detectar inflamação em um paciente
BR9205802A (pt) Processo para a produção extracelular de proteina de heme heteróloga em um fungo filamentoso, construção de DNA, vetor de expressão de recombinante e célula hospedeira
DK0894126T3 (da) Alkalisk phosphatase-deficient trådformet svamp
HK1072610A1 (en) High level constitutive production of anthrax protective antigen
BR0008772B1 (pt) vetor de expressão, célula bacteriana ou fúngica cultivada, processos para expandir in vitro células hematopoiéticas e progenitores de células hematopoiéticas, e para detectar a presença de rna de ligando zalfa11 e de ligando zalfa 11 in vitro em uma amostra biológica.
IL173474A0 (en) Methods for producing recombinant proteins
DK0737747T3 (da) Cytoplasmatisk ekspression af antistoffer, antistoffragmenter og antistoffragmentfusionsmolekyler I E. coli
HUP0303843A2 (hu) CLyA-hemolizin alkalmazása proteinek exkretáltatására
SG163592A1 (en) Methods and compositions for increasing longevity and protein yield from a cell culture
EA201000945A1 (ru) Конструирование системы секреции на основе sm-белков
EA200100023A1 (ru) Промышленный способ производства гетерологичных белков в пригодных для этого способа штаммах е.coli
TW200510544A (en) Improved method for the recombinant production of polypeptides
ATE288476T1 (de) Herstellung von proteinen
ATE123524T1 (de) Herstellungsverfahren für chymosin.
CN104593402A (zh) 运用大肠杆菌作为生物反应器生产重组的抗肿瘤19肽的方法
DK0725822T3 (da) Fremgangsmåde til rekombinant fremstilling af proteiner i gær
ATE409746T1 (de) Neuer spannungsabhängiger kaliumkanal und seine verwendung zur entwicklung von therapeutika
DK0801682T3 (da) Fremgangsmåde til fremstilling af proteiner
ATE403863T1 (de) Verfahren zum nachweis von intrazellulären atp und/oder genexpression
DE69434135D1 (de) Rekombinante dnase b aus streptococcus pyogenes
SE8903865D0 (sv) Expression of heterologous proteins using eukaryotic cells
ATE470700T1 (de) Bazillus zelle für die herstellung von proteinen