EA200100023A1 - Промышленный способ производства гетерологичных белков в пригодных для этого способа штаммах е.coli - Google Patents

Промышленный способ производства гетерологичных белков в пригодных для этого способа штаммах е.coli

Info

Publication number
EA200100023A1
EA200100023A1 EA200100023A EA200100023A EA200100023A1 EA 200100023 A1 EA200100023 A1 EA 200100023A1 EA 200100023 A EA200100023 A EA 200100023A EA 200100023 A EA200100023 A EA 200100023A EA 200100023 A1 EA200100023 A1 EA 200100023A1
Authority
EA
Eurasian Patent Office
Prior art keywords
manufacture
coli strains
coli
proteins suitable
industrial
Prior art date
Application number
EA200100023A
Other languages
English (en)
Inventor
Жером Пьеррар
Кароль Гиттон
Оливье Фавр-Бюлль
Original Assignee
Авентис Анималь Нютрисьон С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Авентис Анималь Нютрисьон С.А. filed Critical Авентис Анималь Нютрисьон С.А.
Publication of EA200100023A1 publication Critical patent/EA200100023A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Abstract

Настоящее изобретение относится к новому промышленному способу получения гетерологичных белков в E. coli, в котором осуществляют посев и культивирование в подходящей культуральной среде бактерий E. coli, модифицированных подходящей системой экспрессии гетерологичных белков, отличающемуся тем, что штаммом E. coli является штамм E. coli W.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200100023A 1998-06-10 1999-06-08 Промышленный способ производства гетерологичных белков в пригодных для этого способа штаммах е.coli EA200100023A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9807474A FR2780416B1 (fr) 1998-06-10 1998-06-10 Procede industriel de production de proteines heterologues chez e. coli et souches utiles pour le procede
PCT/FR1999/001343 WO1999064607A1 (fr) 1998-06-10 1999-06-08 Procede industriel de production de proteines heterologues chez e. coli et souches utiles pour le procede

Publications (1)

Publication Number Publication Date
EA200100023A1 true EA200100023A1 (ru) 2001-06-25

Family

ID=9527357

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200100023A EA200100023A1 (ru) 1998-06-10 1999-06-08 Промышленный способ производства гетерологичных белков в пригодных для этого способа штаммах е.coli

Country Status (8)

Country Link
EP (1) EP1084258A1 (ru)
JP (1) JP2002517252A (ru)
AU (1) AU753879B2 (ru)
CA (1) CA2331150A1 (ru)
EA (1) EA200100023A1 (ru)
FR (1) FR2780416B1 (ru)
IL (1) IL140073A0 (ru)
WO (1) WO1999064607A1 (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2822460B1 (fr) * 2001-03-26 2005-04-29 Rhodia Chimie Sa Procede de preparation enantioselectif d'acides carboxyliques optiquement actifs par hydrolyse enzymatique de nitriles
JPWO2003085108A1 (ja) * 2002-04-10 2005-08-11 味の素株式会社 ヒダントイナーゼ遺伝子及びカルバミラーゼ遺伝子を有する組換えｄｎａ、並びにアミノ酸製造方法
DE602004021778D1 (de) * 2003-02-27 2009-08-13 Basf Se Modifizierte nitrilasen und deren verwendung in verfahren zur herstellung von carbonsäuren
JP5808527B2 (ja) * 2010-04-09 2015-11-10 三洋化成工業株式会社 有用物質製造方法
JP5808526B2 (ja) * 2010-04-09 2015-11-10 三洋化成工業株式会社 有用物質製造方法
JP5808529B2 (ja) * 2010-06-28 2015-11-10 三洋化成工業株式会社 有用物質生産方法
JP5808530B2 (ja) * 2010-06-28 2015-11-10 三洋化成工業株式会社 有用物質生産方法
EP2841584B1 (en) 2012-04-26 2021-03-17 Adisseo France S.A.S. A method of production of 2,4-dihydroxybutyric acid
EP2872639B1 (en) 2012-07-11 2018-03-14 Institut National Des Sciences Appliquees A microorganism modified for the production of 1,3-propanediol
IN2014DN10637A (ru) 2012-07-11 2015-09-11 Adisseo France Sas

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2209591A1 (de) * 1971-03-04 1972-09-14 Asahi Kasei Kogyo K.K., Osaka (Japan) Verfahren zur biotechnischen Herstellung von L-5-Hydroxytryptophan
US4246346A (en) * 1978-09-05 1981-01-20 Aktiebolaget Fermenta Antibiotic and steroid transformation process
US5000000A (en) * 1988-08-31 1991-03-19 University Of Florida Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes
GB8821795D0 (en) * 1988-09-16 1988-10-19 Erba Carlo Spa New derivatives of human/bovine basic fibroplast growth factor
ES2020792A6 (es) * 1990-08-03 1991-09-16 Antibioticos Sa Un procedimiento enzimatico para la presentacion de acido 7-amino-cefa-losporanico y un procedimiento para expresar la enzima 7b (4-carboxibutanamido) cefalosporinacilasa.
IT1252308B (it) * 1990-12-21 1995-06-08 Antibioticos Spa Procedimento enzimatico per la produzione di acido 7- amminocefalosporanico e derivati
FR2694571B1 (fr) * 1992-08-10 1994-11-04 Rhone Poulenc Chimie Polypeptides possédant une activité nitrilase, séquence d'ADN codant pour lesdits polypeptides, cassettes d'expression et micro-organismes hôtes permettant leur obtention.
JP3880636B2 (ja) * 1994-01-10 2007-02-14 味の素株式会社 発酵法によるｌ−グルタミン酸の製造法
FR2755143B1 (fr) * 1996-10-25 1998-11-27 Rhone Poulenc Nutrition Animal Procede de preparation de l'acide 2-hydroxy-4-methylthio-butyrique par utilisation d'une nitrilase

Also Published As

Publication number Publication date
AU4046699A (en) 1999-12-30
EP1084258A1 (fr) 2001-03-21
IL140073A0 (en) 2002-02-10
WO1999064607A1 (fr) 1999-12-16
CA2331150A1 (fr) 1999-12-16
FR2780416B1 (fr) 2002-12-20
JP2002517252A (ja) 2002-06-18
AU753879B2 (en) 2002-10-31
FR2780416A1 (fr) 1999-12-31

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