EA200100023A1 - INDUSTRIAL METHOD OF MANUFACTURE OF HETEROLOGICAL PROTEINS SUITABLE FOR THIS METHOD OF E.COLI STRAINS - Google Patents

INDUSTRIAL METHOD OF MANUFACTURE OF HETEROLOGICAL PROTEINS SUITABLE FOR THIS METHOD OF E.COLI STRAINS

Info

Publication number
EA200100023A1
EA200100023A1 EA200100023A EA200100023A EA200100023A1 EA 200100023 A1 EA200100023 A1 EA 200100023A1 EA 200100023 A EA200100023 A EA 200100023A EA 200100023 A EA200100023 A EA 200100023A EA 200100023 A1 EA200100023 A1 EA 200100023A1
Authority
EA
Eurasian Patent Office
Prior art keywords
manufacture
coli strains
coli
proteins suitable
industrial
Prior art date
Application number
EA200100023A
Other languages
Russian (ru)
Inventor
Жером Пьеррар
Кароль Гиттон
Оливье Фавр-Бюлль
Original Assignee
Авентис Анималь Нютрисьон С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Авентис Анималь Нютрисьон С.А. filed Critical Авентис Анималь Нютрисьон С.А.
Publication of EA200100023A1 publication Critical patent/EA200100023A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Abstract

Настоящее изобретение относится к новому промышленному способу получения гетерологичных белков в E. coli, в котором осуществляют посев и культивирование в подходящей культуральной среде бактерий E. coli, модифицированных подходящей системой экспрессии гетерологичных белков, отличающемуся тем, что штаммом E. coli является штамм E. coli W.Международная заявка была опубликована вместе с отчетом о международном поиске.The present invention relates to a new industrial method for the production of heterologous proteins in E. coli, in which E. coli bacteria are sown and cultured in a suitable culture medium modified by a suitable system of expression of heterologous proteins, characterized in that the E. coli strain is E. coli strain W. The international application was published along with an international search report.

EA200100023A 1998-06-10 1999-06-08 INDUSTRIAL METHOD OF MANUFACTURE OF HETEROLOGICAL PROTEINS SUITABLE FOR THIS METHOD OF E.COLI STRAINS EA200100023A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9807474A FR2780416B1 (en) 1998-06-10 1998-06-10 INDUSTRIAL PROCESS FOR PRODUCING HETEROLOGOUS PROTEINS IN E. COLI AND STRAINS USEFUL FOR THE PROCESS
PCT/FR1999/001343 WO1999064607A1 (en) 1998-06-10 1999-06-08 Industrial method for producing heterologous proteins in e.coli and strains useful for said method

Publications (1)

Publication Number Publication Date
EA200100023A1 true EA200100023A1 (en) 2001-06-25

Family

ID=9527357

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200100023A EA200100023A1 (en) 1998-06-10 1999-06-08 INDUSTRIAL METHOD OF MANUFACTURE OF HETEROLOGICAL PROTEINS SUITABLE FOR THIS METHOD OF E.COLI STRAINS

Country Status (8)

Country Link
EP (1) EP1084258A1 (en)
JP (1) JP2002517252A (en)
AU (1) AU753879B2 (en)
CA (1) CA2331150A1 (en)
EA (1) EA200100023A1 (en)
FR (1) FR2780416B1 (en)
IL (1) IL140073A0 (en)
WO (1) WO1999064607A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2822460B1 (en) * 2001-03-26 2005-04-29 Rhodia Chimie Sa PROCESS FOR THE ENANTIOSELECTIVE PREPARATION OF OPTICALLY ACTIVE CARBOXYLIC ACIDS BY ENZYMATIC HYDROLYSIS OF NITRILES
JPWO2003085108A1 (en) * 2002-04-10 2005-08-11 味の素株式会社 Recombinant DNA having hydantoinase gene and carbamylase gene, and method for producing amino acid
DE602004021778D1 (en) * 2003-02-27 2009-08-13 Basf Se MODIFIED NITRILASES AND THEIR USE IN PROCEDURES FOR THE PREPARATION OF CARBOXYLIC ACIDS
JP5808527B2 (en) * 2010-04-09 2015-11-10 三洋化成工業株式会社 Method for producing useful substances
JP5808526B2 (en) * 2010-04-09 2015-11-10 三洋化成工業株式会社 Method for producing useful substances
JP5808529B2 (en) * 2010-06-28 2015-11-10 三洋化成工業株式会社 Useful substance production method
JP5808530B2 (en) * 2010-06-28 2015-11-10 三洋化成工業株式会社 Useful substance production method
EP2841584B1 (en) 2012-04-26 2021-03-17 Adisseo France S.A.S. A method of production of 2,4-dihydroxybutyric acid
EP2872639B1 (en) 2012-07-11 2018-03-14 Institut National Des Sciences Appliquees A microorganism modified for the production of 1,3-propanediol
IN2014DN10637A (en) 2012-07-11 2015-09-11 Adisseo France Sas

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2209591A1 (en) * 1971-03-04 1972-09-14 Asahi Kasei Kogyo K.K., Osaka (Japan) Process for the biotechnological production of L-5-hydroxytryptophan
US4246346A (en) * 1978-09-05 1981-01-20 Aktiebolaget Fermenta Antibiotic and steroid transformation process
US5000000A (en) * 1988-08-31 1991-03-19 University Of Florida Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes
GB8821795D0 (en) * 1988-09-16 1988-10-19 Erba Carlo Spa New derivatives of human/bovine basic fibroplast growth factor
ES2020792A6 (en) * 1990-08-03 1991-09-16 Antibioticos Sa A process for the enzymatic preparation of 7-aminocephalosporanic acid.
IT1252308B (en) * 1990-12-21 1995-06-08 Antibioticos Spa ENZYMATIC PROCEDURE FOR THE PRODUCTION OF 7- AMINOCEPHALOSPORANIC ACID AND DERIVATIVES
FR2694571B1 (en) * 1992-08-10 1994-11-04 Rhone Poulenc Chimie Polypeptides having nitrilase activity, DNA sequence coding for said polypeptides, expression cassettes and host microorganisms allowing their production.
JP3880636B2 (en) * 1994-01-10 2007-02-14 味の素株式会社 Method for producing L-glutamic acid by fermentation
FR2755143B1 (en) * 1996-10-25 1998-11-27 Rhone Poulenc Nutrition Animal PROCESS FOR THE PREPARATION OF 2-HYDROXY-4-METHYLTHIO-BUTYRIC ACID USING A NITRILASE

Also Published As

Publication number Publication date
AU4046699A (en) 1999-12-30
EP1084258A1 (en) 2001-03-21
IL140073A0 (en) 2002-02-10
WO1999064607A1 (en) 1999-12-16
CA2331150A1 (en) 1999-12-16
FR2780416B1 (en) 2002-12-20
JP2002517252A (en) 2002-06-18
AU753879B2 (en) 2002-10-31
FR2780416A1 (en) 1999-12-31

Similar Documents

Publication Publication Date Title
AU5102899A (en) Process and materials for production of glucosamine
MXPA03002683A (en) ESCHERICHIA COLI CEPAS WHICH OVERPRODUCTS L-TREONIN AND PROCEDURES FOR PRODUCTION OF L-TREONIN BY FERMENTATION ..
ATE290599T1 (en) CELLULASE FROM ACTINOMYCETES AND PRODUCTION PROCESS THEREOF
Anbu et al. Extracellular keratinase from Trichophyton sp. HA-2 isolated from feather dumping soil
DE60313188D1 (en) METHOD AND MEDIA FOR CONTROLLING THE SIALYING OF PROTEINS PRODUCED BY MAMMALIAN CELLS
ATE57391T1 (en) CHITINASE PRODUCING BACTERIA.
EP1360314A4 (en) Chemically defined medium for cultured mammalian cells
PL1863920T3 (en) Method for improved isolation of recombinantly produced proteins
DE69834741D1 (en) CELLULASE FROM ACTINOMYCETES AND METHOD OF MANUFACTURING THEREOF
SG161210A1 (en) Methods for expression and purification of recombinant human growth hormone
BR9803346B1 (en) Transformed Microorganisms, as well as Process for the Preparation of L-Cysteine, L-Cystine, N-Acetyl-Serine or Thiazolidine Derivatives
EA200100023A1 (en) INDUSTRIAL METHOD OF MANUFACTURE OF HETEROLOGICAL PROTEINS SUITABLE FOR THIS METHOD OF E.COLI STRAINS
HUP0303843A2 (en) Use of clya hemolysin for excretion of proteins
IL155482A (en) Method for increasing product yield of a mammalian polypeptide produced by recombinant bacterial host cells
PT1194575E (en) STIMULATION FACTOR OF MODIFIED HUMAN GRANULOCYTE COLONIES AND PROCESSES FOR THEIR PRODUCTION
ATE353953T1 (en) HOST CELL EXPRESSING REDUCED AMOUNTS OF A METALLOPROTEASE AND METHODS OF USING THIS HOST CELL FOR PROTEIN PRODUCTION
EA199600001A3 (en) Process of extraction of periplasmic proteins from prokaryotic microorganisms in the presence of arginine
CR6905A (en) BETTER INSECTICIDES IMPROVED AND METHODS TO MAKE AND USE THEM.
RU94043769A (en) Method of protein c production increase, method of increase of its modification level
FR2815640B1 (en) PROCESS FOR PRODUCING PROTEINS BY ELECTROPULSATION OF YEAST
DK1639119T3 (en) Process for microbiological isomerization of alpha-hydroxycarboxylic acids
ATE293170T1 (en) PHAGE-DEPENDENT SUPERPRODUCTION OF BIOLOGICALLY ACTIVE PROTEINS AND PEPTIDES
TR200401332T4 (en) Method for production of biological material
PT1246909E (en) PROCESS FOR THE PRODUCTION OF HYDROXINITRILE LIASES
ATE288476T1 (en) PRODUCTION OF PROTEINS