CY1105254T1 - Θepαπεια του διαβητη με θειαζολιδινδιονη, εκκριταγωγο ινσουλινης και διγουανιδιο - Google Patents

Θepαπεια του διαβητη με θειαζολιδινδιονη, εκκριταγωγο ινσουλινης και διγουανιδιο

Info

Publication number
CY1105254T1
CY1105254T1 CY20051101486T CY051101486T CY1105254T1 CY 1105254 T1 CY1105254 T1 CY 1105254T1 CY 20051101486 T CY20051101486 T CY 20051101486T CY 051101486 T CY051101486 T CY 051101486T CY 1105254 T1 CY1105254 T1 CY 1105254T1
Authority
CY
Cyprus
Prior art keywords
insulin
secretago
diguanidium
thiazolidinedione
diabetes
Prior art date
Application number
CY20051101486T
Other languages
Greek (el)
English (en)
Inventor
Robin Edwin Buckingham
Stephen Alistair Smith
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of CY1105254T1 publication Critical patent/CY1105254T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/64Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
CY20051101486T 1997-07-18 2005-12-07 Θepαπεια του διαβητη με θειαζολιδινδιονη, εκκριταγωγο ινσουλινης και διγουανιδιο CY1105254T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9715295A GB9715295D0 (en) 1997-07-18 1997-07-18 Novel method of treatment
PCT/GB1998/002110 WO1999003477A1 (en) 1997-07-18 1998-07-16 Treatment of diabetes with thiazolidinedione, insulin secretagogue and diguanide

Publications (1)

Publication Number Publication Date
CY1105254T1 true CY1105254T1 (el) 2010-03-03

Family

ID=10816167

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20051101486T CY1105254T1 (el) 1997-07-18 2005-12-07 Θepαπεια του διαβητη με θειαζολιδινδιονη, εκκριταγωγο ινσουλινης και διγουανιδιο

Country Status (39)

Country Link
EP (1) EP1001783B1 (enEXAMPLES)
JP (2) JP2001510159A (enEXAMPLES)
KR (1) KR100671918B1 (enEXAMPLES)
CN (1) CN1264303A (enEXAMPLES)
AP (1) AP1352A (enEXAMPLES)
AR (1) AR016349A1 (enEXAMPLES)
AT (1) ATE305790T1 (enEXAMPLES)
AU (1) AU8448898A (enEXAMPLES)
BG (1) BG64785B1 (enEXAMPLES)
BR (1) BR9810445A (enEXAMPLES)
CA (1) CA2296653C (enEXAMPLES)
CO (1) CO4940420A1 (enEXAMPLES)
CY (1) CY1105254T1 (enEXAMPLES)
DE (1) DE69831808T2 (enEXAMPLES)
DK (1) DK1001783T3 (enEXAMPLES)
DZ (1) DZ2562A1 (enEXAMPLES)
EA (1) EA003021B1 (enEXAMPLES)
ES (1) ES2251093T3 (enEXAMPLES)
GB (1) GB9715295D0 (enEXAMPLES)
HU (1) HUP0003629A3 (enEXAMPLES)
ID (1) ID24211A (enEXAMPLES)
IL (1) IL134046A0 (enEXAMPLES)
IN (1) IN189275B (enEXAMPLES)
MA (1) MA24607A1 (enEXAMPLES)
MY (1) MY155219A (enEXAMPLES)
NO (1) NO325727B1 (enEXAMPLES)
NZ (2) NZ501164A (enEXAMPLES)
OA (1) OA11279A (enEXAMPLES)
PE (1) PE99599A1 (enEXAMPLES)
PL (2) PL197844B1 (enEXAMPLES)
SA (1) SA98190468B1 (enEXAMPLES)
SI (1) SI1001783T1 (enEXAMPLES)
SK (1) SK285484B6 (enEXAMPLES)
TR (1) TR200000134T2 (enEXAMPLES)
TW (1) TW505516B (enEXAMPLES)
UA (1) UA70303C2 (enEXAMPLES)
UY (1) UY25102A1 (enEXAMPLES)
WO (1) WO1999003477A1 (enEXAMPLES)
ZA (1) ZA986363B (enEXAMPLES)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6011049A (en) * 1997-02-19 2000-01-04 Warner-Lambert Company Combinations for diabetes
US6099862A (en) * 1998-08-31 2000-08-08 Andrx Corporation Oral dosage form for the controlled release of a biguanide and sulfonylurea
EP1813273A1 (en) * 1998-11-12 2007-08-01 Smithkline Beecham Plc Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
SE9902918D0 (sv) * 1999-08-13 1999-08-13 Pharmacia & Upjohn Ab Methods for identification of compounds stimulating insulin secretion
AU1403501A (en) * 1999-11-16 2001-05-30 Smithkline Beecham Plc Novel composition and use
AR030920A1 (es) 1999-11-16 2003-09-03 Smithkline Beecham Plc Composiciones farmaceuticas para el tratamiento de la diabetes mellitus y condiciones asociadas con la diabetes mellitus, y procedimientos para preparar dichas composiciones
FR2812547B1 (fr) * 2000-08-04 2002-10-31 Lipha Composition pharmaceutique comprenant une association metformine et derive de thiazolidinedione et son utilisation pour la preparation de medicaments destines a traiter le diabete
ATE508738T1 (de) 2001-01-12 2011-05-15 Sun Pharma Advanced Res Co Ltd System zur beabstandeten abgabe von arzneimitteln
ITFI20010126A1 (it) * 2001-07-09 2003-01-09 Molteni & C Composizioni farmaceutiche per uso orale,contenenti,in combinazione,metformina e gliclazide
EP1429747A4 (en) * 2001-07-10 2005-01-05 Kos Life Sciences Inc CORE FORMULATION WITH PIOGLITAZONE HYDROCHLORIDE AND A BIGUANIDE
PL376577A1 (pl) 2002-06-17 2006-01-09 Themis Laboratories Private Limited Wielowarstwowe tabletki zawierające tiazolidinedion i biguanidy oraz metody ich wytwarzania
KR101363679B1 (ko) * 2002-09-20 2014-02-14 안드렉스 랩스 엘엘씨 약제학적 정제
UA80991C2 (en) 2002-10-07 2007-11-26 Solid preparation containing an insulin resistance improving drug and an active ingredient useful as a remedy for diabetes
PL1677792T3 (pl) 2003-10-31 2016-05-31 Takeda Pharmaceuticals Co Stały preparat zawierający pioglitazon, glimepiryd i ester polioksyetylenosorbitanu z kwasem tłuszczowym
MXPA05010977A (es) * 2005-10-12 2007-04-11 Abdala Leopoldo Espinosa Composiciones farmaceuticas que comprenden sustancias antidiabeticas combinadas para su uso en diabetes mellitus.
KR100812538B1 (ko) * 2006-10-23 2008-03-11 한올제약주식회사 약물 제어방출형 메트포르민-글리메피리드 복합제제
CN101417130B (zh) * 2007-10-22 2010-10-06 鲁南制药集团股份有限公司 一种治疗ⅱ型糖尿病及其并发症的药物组合物
US11607441B2 (en) 2017-10-20 2023-03-21 Novmetapharma Co., Ltd. Pharmaceutical composition for preventing or treating diabetes, containing zinc salt, cyclo-hispro and antidiabetic drug as active ingredients

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS5697277A (en) * 1980-01-07 1981-08-05 Takeda Chem Ind Ltd Thiazolidine derivative
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
US4582839A (en) * 1984-03-21 1986-04-15 Takeda Chemical Industries, Ltd. 2,4-thiazolidinediones
CN1003445B (zh) * 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物,其制备方法和用途
JPH06779B2 (ja) * 1985-06-10 1994-01-05 武田薬品工業株式会社 チアゾリジオン誘導体およびそれを含んでなる医薬組成物
US4812570A (en) * 1986-07-24 1989-03-14 Takeda Chemical Industries, Ltd. Method for producing thiazolidinedione derivatives
US4791125A (en) * 1987-12-02 1988-12-13 Pfizer Inc. Thiazolidinediones as hypoglycemic and anti-atherosclerosis agents
WO1989008651A1 (en) * 1988-03-08 1989-09-21 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
FI904414A7 (fi) * 1988-03-08 1990-09-07 Pfizer Tiatsolidiinidioni-hypoglykeemisesti vaikuttavat aineet
WO1991007107A1 (en) * 1989-11-13 1991-05-30 Pfizer Inc. Oxazolidinedione hypoglycemic agents
JPH04210683A (ja) * 1990-12-06 1992-07-31 Terumo Corp チアゾリジン−2,4−ジオン誘導体およびこれを含有する糖尿病合併症治療薬
ATE151634T1 (de) * 1991-08-26 1997-05-15 Upjohn Co Flüssiges nahrungsmittel, das 3- guanidinopropionsäure enthält
US5917052A (en) * 1994-09-28 1999-06-29 Shaman Pharmaceuticals, Inc. Hypoglycemic agent from cryptolepis
TW438587B (en) * 1995-06-20 2001-06-07 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
CZ299310B6 (cs) * 1997-06-18 2008-06-18 Smithkline Beecham Plc Lécivo pro lécbu diabetes mellitus a stavu spojených s diabetes mellitus

Also Published As

Publication number Publication date
EP1001783B1 (en) 2005-10-05
UA70303C2 (uk) 2004-10-15
NO20000228D0 (no) 2000-01-17
KR20010021947A (ko) 2001-03-15
KR100671918B1 (ko) 2007-01-22
PL197844B1 (pl) 2008-05-30
SI1001783T1 (sl) 2006-02-28
SK592000A3 (en) 2000-09-12
ES2251093T3 (es) 2006-04-16
ATE305790T1 (de) 2005-10-15
OA11279A (en) 2003-07-31
BG64785B1 (bg) 2006-04-28
IL134046A0 (en) 2001-04-30
NZ501164A (en) 2001-06-29
DE69831808T2 (de) 2006-07-06
GB9715295D0 (en) 1997-09-24
JP2005213273A (ja) 2005-08-11
NZ511608A (en) 2002-12-20
AR016349A1 (es) 2001-07-04
DZ2562A1 (fr) 2003-02-15
SK285484B6 (sk) 2007-02-01
AU8448898A (en) 1999-02-10
DE69831808D1 (de) 2006-02-16
AP2000001733A0 (en) 2000-03-31
NO325727B1 (no) 2008-07-07
CA2296653C (en) 2007-10-02
UY25102A1 (es) 2000-12-29
MA24607A1 (fr) 1999-04-01
MY155219A (en) 2015-09-30
EA200000139A1 (ru) 2000-06-26
BG104135A (en) 2000-10-31
JP2001510159A (ja) 2001-07-31
DK1001783T3 (da) 2006-02-06
HUP0003629A2 (hu) 2001-07-30
HK1028550A1 (en) 2001-02-23
CN1264303A (zh) 2000-08-23
BR9810445A (pt) 2000-09-05
EA003021B1 (ru) 2002-12-26
HUP0003629A3 (en) 2003-04-28
PL198017B1 (pl) 2008-05-30
EP1001783A1 (en) 2000-05-24
ZA986363B (en) 2000-01-17
ID24211A (id) 2000-07-13
NO20000228L (no) 2000-01-17
WO1999003477A1 (en) 1999-01-28
PE99599A1 (es) 1999-12-18
SA98190468B1 (ar) 2007-01-20
CA2296653A1 (en) 1999-01-28
IN189275B (enEXAMPLES) 2003-01-25
TW505516B (en) 2002-10-11
PL338126A1 (en) 2000-09-25
CO4940420A1 (es) 2000-07-24
AP1352A (en) 2004-12-24
TR200000134T2 (tr) 2000-09-21

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