WO2001047509A3 - Composition for the treatment diabetes mellitus containing an insuline sensitizer and agent used in the treatment of cardiac conditions - Google Patents

Composition for the treatment diabetes mellitus containing an insuline sensitizer and agent used in the treatment of cardiac conditions Download PDF

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Publication number
WO2001047509A3
WO2001047509A3 PCT/GB2000/005006 GB0005006W WO0147509A3 WO 2001047509 A3 WO2001047509 A3 WO 2001047509A3 GB 0005006 W GB0005006 W GB 0005006W WO 0147509 A3 WO0147509 A3 WO 0147509A3
Authority
WO
WIPO (PCT)
Prior art keywords
treatment
diabetes mellitus
cardiac conditions
agent used
insuline
Prior art date
Application number
PCT/GB2000/005006
Other languages
French (fr)
Other versions
WO2001047509A2 (en
Inventor
Robin Edward Buckingham
Original Assignee
Smithkline Beecham Plc
Robin Edward Buckingham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9930692.0A external-priority patent/GB9930692D0/en
Priority claimed from GBGB9930689.6A external-priority patent/GB9930689D0/en
Priority claimed from GBGB9930688.8A external-priority patent/GB9930688D0/en
Priority claimed from GBGB9930690.4A external-priority patent/GB9930690D0/en
Application filed by Smithkline Beecham Plc, Robin Edward Buckingham filed Critical Smithkline Beecham Plc
Priority to AU23826/01A priority Critical patent/AU2382601A/en
Priority to EP00987579A priority patent/EP1261373A2/en
Priority to JP2001548104A priority patent/JP2003518493A/en
Publication of WO2001047509A2 publication Critical patent/WO2001047509A2/en
Publication of WO2001047509A3 publication Critical patent/WO2001047509A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

A method for the treatment of diabetes mellitus, especially Type II diabetes and the cardiac conditions associated with diabetes mellitus in a mammal such as a human, which method comprises administering an effective non-toxic and pharmaceutically acceptable amount of an insulin sensitiser, such as Compound (I), and an agent used in the treatment of the cardiac conditions associated with diabetes mellitus.
PCT/GB2000/005006 1999-12-24 2000-12-22 Composition for the treatment diabetes mellitus containing an insuline sensitizer and agent used in the treatment of cardiac conditions WO2001047509A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU23826/01A AU2382601A (en) 1999-12-24 2000-12-22 Novel method of treatment
EP00987579A EP1261373A2 (en) 1999-12-24 2000-12-22 Composition for the treatment diabetes mellitus containing an insuline sensitizer and agent used in the treatment of cardiac conditions
JP2001548104A JP2003518493A (en) 1999-12-24 2000-12-22 New treatment methods

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB9930688.8 1999-12-24
GBGB9930692.0A GB9930692D0 (en) 1999-12-24 1999-12-24 Novel method of treatment
GB9930692.0 1999-12-24
GBGB9930689.6A GB9930689D0 (en) 1999-12-24 1999-12-24 Novel method of treatment
GB9930689.6 1999-12-24
GBGB9930688.8A GB9930688D0 (en) 1999-12-24 1999-12-24 Novel method of treatment
GB9930690.4 1999-12-24
GBGB9930690.4A GB9930690D0 (en) 1999-12-24 1999-12-24 Novel method of treatment

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10/168,872 A-371-Of-International US20030060489A1 (en) 1999-12-24 2000-12-22 Novel method of treatment
US10/803,300 Continuation US20040176373A1 (en) 1999-12-24 2004-03-18 Novel method of treatment

Publications (2)

Publication Number Publication Date
WO2001047509A2 WO2001047509A2 (en) 2001-07-05
WO2001047509A3 true WO2001047509A3 (en) 2002-09-12

Family

ID=27451929

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/005006 WO2001047509A2 (en) 1999-12-24 2000-12-22 Composition for the treatment diabetes mellitus containing an insuline sensitizer and agent used in the treatment of cardiac conditions

Country Status (4)

Country Link
EP (1) EP1261373A2 (en)
JP (1) JP2003518493A (en)
AU (1) AU2382601A (en)
WO (1) WO2001047509A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE341343T1 (en) 2000-12-26 2006-10-15 Sankyo Co MEDICAL COMPOSITIONS CONTAINING DIURETIC AND INSULIN RESISTANCE IMPROVEMENT AGENT
CN100377744C (en) * 2002-07-05 2008-04-02 安徽省生物医学研究所 Compound medicine for predicting ACEI pressure reducing medicine effect
ES2660170T3 (en) 2007-01-25 2018-03-21 NAIA Metabolic, Inc. Insulin sensitizers and treatment methods

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0861666A2 (en) * 1995-06-20 1998-09-02 Takeda Chemical Industries, Ltd. Pharmaceutical composition for use in treatment of diabetes
EP0930076A1 (en) * 1996-07-15 1999-07-21 Sankyo Company Limited Medicinal compositions
WO2000027434A1 (en) * 1998-11-11 2000-05-18 Smithkline Beecham P.L.C. Combinations comprising a beta-agonist and a further antidiabetic agent

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0861666A2 (en) * 1995-06-20 1998-09-02 Takeda Chemical Industries, Ltd. Pharmaceutical composition for use in treatment of diabetes
US5965584A (en) * 1995-06-20 1999-10-12 Takeda Chemical Industries, Ltd. Pharmaceutical composition
EP0930076A1 (en) * 1996-07-15 1999-07-21 Sankyo Company Limited Medicinal compositions
WO2000027434A1 (en) * 1998-11-11 2000-05-18 Smithkline Beecham P.L.C. Combinations comprising a beta-agonist and a further antidiabetic agent

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DAGOGO-JACK S ET AL: "PATHOPHYSIOLOGY OF TYPE 2 DIABETES AND MODES OF ACTION OF THERAPEUTIC INTERVENTIONS", ARCHIVES OF INTERNAL MEDICINE, XX, XX, vol. 157, no. 16, 8 September 1997 (1997-09-08), pages 1802 - 1817, XP000872498 *
HOSOKAWA, M. ET AL: "Troglitazone inhibits bicarbonate secretion in rat and human duodenum", J. PHARMACOL. EXP. THER. (1999), 290(3), 1080-1084, XP008002057 *
SHIMOYAMA, MASAKI ET AL: "Hemodynamic basis for the acute cardiac effects of troglitazone in isolated perfused rat hearts.", DIABETES, (MARCH, 1999) VOL. 48, NO. 3, PP. 609-615., XP001035237 *

Also Published As

Publication number Publication date
WO2001047509A2 (en) 2001-07-05
AU2382601A (en) 2001-07-09
EP1261373A2 (en) 2002-12-04
JP2003518493A (en) 2003-06-10

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