CU23253B7 - PREPARACION FARMACéUTICA ESTABILIZADA DE DERIVADOS DE áCIDO GAMMA-AMINOBUTIRICO Y PROCESO PARA ELABORAR LA MISMA - Google Patents
PREPARACION FARMACéUTICA ESTABILIZADA DE DERIVADOS DE áCIDO GAMMA-AMINOBUTIRICO Y PROCESO PARA ELABORAR LA MISMAInfo
- Publication number
- CU23253B7 CU23253B7 CU20000256A CU20000256A CU23253B7 CU 23253 B7 CU23253 B7 CU 23253B7 CU 20000256 A CU20000256 A CU 20000256A CU 20000256 A CU20000256 A CU 20000256A CU 23253 B7 CU23253 B7 CU 23253B7
- Authority
- CU
- Cuba
- Prior art keywords
- pharmaceutical preparation
- gamma
- prepare
- same
- acid derivatives
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical class NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 title 1
- -1 4-amino-3-substituted-butanoic acid Chemical class 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polymerisation Methods In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Esta invencion proporciona una preparacion farmacÉutica estabilizada de Acido 4-amino-3-substituído-butanoico que puede obtenerse incorporando un aminoAcido como estabilizador.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13311398 | 1998-05-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
CU23253B7 true CU23253B7 (es) | 2007-12-17 |
Family
ID=15097118
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CU20000256A CU23253B7 (es) | 1998-05-15 | 2000-11-15 | PREPARACION FARMACéUTICA ESTABILIZADA DE DERIVADOS DE áCIDO GAMMA-AMINOBUTIRICO Y PROCESO PARA ELABORAR LA MISMA |
Country Status (37)
Country | Link |
---|---|
US (1) | US7309719B1 (es) |
EP (1) | EP1077692B1 (es) |
JP (1) | JP4612923B2 (es) |
KR (1) | KR100602047B1 (es) |
CN (1) | CN1303991C (es) |
AR (1) | AR020323A1 (es) |
AT (1) | ATE271864T1 (es) |
AU (1) | AU768277B2 (es) |
BR (1) | BR9910508B1 (es) |
CA (1) | CA2327285C (es) |
CO (1) | CO5021224A1 (es) |
CR (1) | CR6026A (es) |
CU (1) | CU23253B7 (es) |
DE (1) | DE69918977T2 (es) |
DK (1) | DK1077692T3 (es) |
EG (1) | EG26803A (es) |
ES (1) | ES2221385T3 (es) |
GT (1) | GT199900069A (es) |
HK (1) | HK1036586A1 (es) |
HN (1) | HN1999000072A (es) |
HU (1) | HU228771B1 (es) |
ID (1) | ID27724A (es) |
IL (2) | IL139298A0 (es) |
IS (1) | IS2233B (es) |
MY (1) | MY157878A (es) |
NO (1) | NO328959B1 (es) |
NZ (1) | NZ508015A (es) |
PA (1) | PA8472801A1 (es) |
PE (1) | PE20000556A1 (es) |
PL (1) | PL204921B1 (es) |
PT (1) | PT1077692E (es) |
SI (1) | SI1077692T1 (es) |
SV (1) | SV1999000064A (es) |
TW (1) | TWI243054B (es) |
UY (1) | UY25512A1 (es) |
WO (1) | WO1999059573A1 (es) |
ZA (1) | ZA200006484B (es) |
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PL189872B1 (pl) | 1996-07-24 | 2005-10-31 | Warner Lambert Co | Zastosowanie izobutylogaby i jej pochodnych do wytwarzania leku do leczenia bólu |
EP1384473A1 (en) * | 2000-06-16 | 2004-01-28 | Teva Pharmaceutical Industries Ltd. | Stable gabapentin containing more than 20 ppm of chlorine ion |
EP1289364B1 (en) * | 2000-06-16 | 2003-12-10 | Teva Pharmaceutical Industries Ltd. | Stable gabapentin containing more than 2o ppm of chlorine ion |
EP1430893A1 (en) * | 2000-06-16 | 2004-06-23 | Teva Pharmaceutical Industries Ltd. | Stable gabapentin containing more than 20 ppm of chloride ion |
HUP0301919A3 (en) * | 2000-06-16 | 2006-01-30 | Teva Pharma | Stable gabapentin having ph within a controlled range |
US7056951B2 (en) * | 2000-09-26 | 2006-06-06 | Mutual Pharmaceutical Co., Inc. | Stable solid dosage forms of amino acids and processes for producing same |
OA12604A (en) * | 2001-05-25 | 2006-06-08 | Warner Lambert Co | Liquid pharmaceutical composition. |
DE602004006443T2 (de) * | 2004-02-04 | 2008-01-10 | Alembic Ltd., Vadodara | Beschichtete minitabletten von venlafaxinhydrochlorid mit verlängerter freisetzung |
EP1761255A1 (en) * | 2004-05-17 | 2007-03-14 | Odessa Pharma LLC | Decreasing brain neuronal glutamate levels using alpha-keto branched chain amino acids |
NL2000281C2 (nl) | 2005-11-02 | 2007-08-07 | Pfizer Prod Inc | Vaste farmaceutische samenstellingen die pregabaline bevatten. |
WO2007107835A2 (en) * | 2006-03-17 | 2007-09-27 | Aurobindo Pharma Limited | Stable liquid formulations of antiepileptic agents |
DE102007019071A1 (de) | 2007-04-23 | 2008-10-30 | Ratiopharm Gmbh | Stabilisierte pharmazeutische Zusammensetzung enthaltend Pregabalin |
FR2918567B1 (fr) * | 2007-07-11 | 2012-08-03 | Pf Medicament | Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine. |
EP2116618A1 (en) | 2008-05-09 | 2009-11-11 | Agency for Science, Technology And Research | Diagnosis and treatment of Kawasaki disease |
KR101709904B1 (ko) * | 2009-05-19 | 2017-02-23 | 뉴로덤 엘티디 | Dopa 데카르복실라제 억제제의 연속투여용 조성물 |
HU230031B1 (hu) | 2010-03-01 | 2015-05-28 | Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság | Pregabalint és izomaltot tartalmazó stabilizált gyógyszerkészítmény |
EP2389933A1 (en) | 2010-05-25 | 2011-11-30 | Sanovel Ilac Sanayi ve Ticaret A.S. | Controlled-Release Pregabalin Compositions |
TR201005241A1 (tr) | 2010-05-25 | 2012-01-23 | Sanovel �La� San. Ve T�C. A.�. | Kontrollü salım sağlayan pregabalin solüsyon formülasyonu. |
EP2389934A1 (en) | 2010-05-25 | 2011-11-30 | Sanovel Ilac Sanayi ve Ticaret A.S. | Controlled-Release Tablet Formulations of Pregabalin |
HUE047841T2 (hu) | 2010-11-15 | 2020-05-28 | Neuroderm Ltd | L-dopa, dopa dekarboxiláz inhibitorok, katekol-o-metil transzferáz inhibitorok folyamatos adagolására szolgáló készítmények |
TR201903492T4 (tr) | 2012-06-05 | 2019-04-22 | Neuroderm Ltd | Apomorfin ve organik asitler içeren bileşimler ve bunların kullanım alanları. |
CN103494796B (zh) * | 2013-09-30 | 2016-01-20 | 浙江华义医药有限公司 | 普瑞巴林稳定的药物组合物及其制备方法 |
WO2015114509A1 (en) | 2014-01-28 | 2015-08-06 | Ranbaxy Laboratories Limited | Stabilized gastroretentive tablets of pregabalin |
US10258585B2 (en) | 2014-03-13 | 2019-04-16 | Neuroderm, Ltd. | DOPA decarboxylase inhibitor compositions |
HUE064818T2 (hu) | 2014-03-13 | 2024-04-28 | Neuroderm Ltd | Dopa dekarboxiláz inhibitor készítmények |
WO2015144825A1 (en) * | 2014-03-27 | 2015-10-01 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Oral liquid pharmaceutical solution of gabapentin |
MA39272A (fr) * | 2014-04-09 | 2015-10-14 | Arven Ilac Sanayi Ve Ticaret As | Formulations à libération prolongée de gabapentine |
CA2953225A1 (en) | 2015-05-26 | 2016-12-01 | Isa Odidi | Controlled extended release pregabalin |
JP6919119B2 (ja) * | 2017-01-23 | 2021-08-18 | 日新製薬株式会社 | 3位が置換されたγ−アミノ酪酸誘導体を含有する圧縮固形医薬組成物。 |
US20220016061A1 (en) | 2018-10-04 | 2022-01-20 | Medrx Co., Ltd. | Preparation Stabilized by Means of Nonaqueous Solvent |
US10792262B1 (en) * | 2019-07-29 | 2020-10-06 | Saol International Limited | Stabilized formulations of 4-amino-3-substituted butanoic acid derivatives |
US11654124B2 (en) | 2019-07-29 | 2023-05-23 | Amneal Pharmaceuticals Llc | Stabilized formulations of 4-amino-3-substituted butanoic acid derivatives |
CA3159067A1 (en) | 2019-10-25 | 2021-04-29 | Kyoto University | Preventative or therapeutic agent for tauopathy |
US11331293B1 (en) | 2020-11-17 | 2022-05-17 | Neuroderm, Ltd. | Method for treatment of Parkinson's disease |
US11213502B1 (en) | 2020-11-17 | 2022-01-04 | Neuroderm, Ltd. | Method for treatment of parkinson's disease |
US11844754B2 (en) | 2020-11-17 | 2023-12-19 | Neuroderm, Ltd. | Methods for treatment of Parkinson's disease |
CN112843015A (zh) * | 2021-04-08 | 2021-05-28 | 海南鑫开源医药科技有限公司 | 一种加巴喷丁胶囊制剂及其制备方法 |
WO2023055457A1 (en) | 2021-09-29 | 2023-04-06 | Amneal Pharmaceuticals Llc | Baclofen-containing granule formulations and reduced patient exposure to metabolite variations |
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-
1999
- 1999-05-10 DK DK99924166T patent/DK1077692T3/da active
- 1999-05-10 PL PL344218A patent/PL204921B1/pl unknown
- 1999-05-10 CN CNB998061557A patent/CN1303991C/zh not_active Expired - Fee Related
- 1999-05-10 HU HU0102022A patent/HU228771B1/hu not_active IP Right Cessation
- 1999-05-10 WO PCT/US1999/010190 patent/WO1999059573A1/en active IP Right Grant
- 1999-05-10 ID IDW20002352A patent/ID27724A/id unknown
- 1999-05-10 ES ES99924166T patent/ES2221385T3/es not_active Expired - Lifetime
- 1999-05-10 KR KR1020007012759A patent/KR100602047B1/ko not_active IP Right Cessation
- 1999-05-10 AT AT99924166T patent/ATE271864T1/de active
- 1999-05-10 CA CA002327285A patent/CA2327285C/en not_active Expired - Lifetime
- 1999-05-10 US US09/674,815 patent/US7309719B1/en not_active Expired - Fee Related
- 1999-05-10 BR BRPI9910508-0A patent/BR9910508B1/pt not_active IP Right Cessation
- 1999-05-10 NZ NZ508015A patent/NZ508015A/en not_active IP Right Cessation
- 1999-05-10 AU AU40735/99A patent/AU768277B2/en not_active Ceased
- 1999-05-10 IL IL13929899A patent/IL139298A0/xx unknown
- 1999-05-10 SI SI9930624T patent/SI1077692T1/xx unknown
- 1999-05-10 EP EP99924166A patent/EP1077692B1/en not_active Expired - Lifetime
- 1999-05-10 DE DE69918977T patent/DE69918977T2/de not_active Expired - Lifetime
- 1999-05-10 PT PT99924166T patent/PT1077692E/pt unknown
- 1999-05-12 CR CR6026A patent/CR6026A/es unknown
- 1999-05-12 TW TW088107704A patent/TWI243054B/zh not_active IP Right Cessation
- 1999-05-13 EG EG1999050554A patent/EG26803A/en active
- 1999-05-13 MY MYPI99001901A patent/MY157878A/en unknown
- 1999-05-13 PA PA19998472801A patent/PA8472801A1/es unknown
- 1999-05-14 CO CO99030149A patent/CO5021224A1/es unknown
- 1999-05-14 HN HN1999000072A patent/HN1999000072A/es unknown
- 1999-05-14 AR ARP990102313A patent/AR020323A1/es active IP Right Grant
- 1999-05-14 SV SV1999000064A patent/SV1999000064A/es active IP Right Grant
- 1999-05-14 GT GT199900069A patent/GT199900069A/es unknown
- 1999-05-14 UY UY25512A patent/UY25512A1/es not_active IP Right Cessation
- 1999-05-14 PE PE1999000407A patent/PE20000556A1/es not_active Application Discontinuation
- 1999-05-14 JP JP13377399A patent/JP4612923B2/ja not_active Expired - Lifetime
-
2000
- 2000-10-16 IS IS5666A patent/IS2233B/is unknown
- 2000-10-26 IL IL139298A patent/IL139298A/en not_active IP Right Cessation
- 2000-11-09 ZA ZA200006484A patent/ZA200006484B/en unknown
- 2000-11-14 NO NO20005768A patent/NO328959B1/no not_active IP Right Cessation
- 2000-11-15 CU CU20000256A patent/CU23253B7/es unknown
-
2001
- 2001-10-18 HK HK01107298A patent/HK1036586A1/xx not_active IP Right Cessation
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