IL139298A0 - Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same - Google Patents

Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same

Info

Publication number
IL139298A0
IL139298A0 IL13929899A IL13929899A IL139298A0 IL 139298 A0 IL139298 A0 IL 139298A0 IL 13929899 A IL13929899 A IL 13929899A IL 13929899 A IL13929899 A IL 13929899A IL 139298 A0 IL139298 A0 IL 139298A0
Authority
IL
Israel
Prior art keywords
gamma
preparing
same
acid derivatives
pharmaceutical preparations
Prior art date
Application number
IL13929899A
Other languages
English (en)
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=15097118&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL139298(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of IL139298A0 publication Critical patent/IL139298A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymerisation Methods In General (AREA)
IL13929899A 1998-05-15 1999-05-10 Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same IL139298A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP13311398 1998-05-15
PCT/US1999/010190 WO1999059573A1 (en) 1998-05-15 1999-05-10 Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same

Publications (1)

Publication Number Publication Date
IL139298A0 true IL139298A0 (en) 2001-11-25

Family

ID=15097118

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13929899A IL139298A0 (en) 1998-05-15 1999-05-10 Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same
IL139298A IL139298A (en) 1998-05-15 2000-10-26 Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL139298A IL139298A (en) 1998-05-15 2000-10-26 Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same

Country Status (37)

Country Link
US (1) US7309719B1 (xx)
EP (1) EP1077692B1 (xx)
JP (1) JP4612923B2 (xx)
KR (1) KR100602047B1 (xx)
CN (1) CN1303991C (xx)
AR (1) AR020323A1 (xx)
AT (1) ATE271864T1 (xx)
AU (1) AU768277B2 (xx)
BR (1) BR9910508B1 (xx)
CA (1) CA2327285C (xx)
CO (1) CO5021224A1 (xx)
CR (1) CR6026A (xx)
CU (1) CU23253B7 (xx)
DE (1) DE69918977T2 (xx)
DK (1) DK1077692T3 (xx)
EG (1) EG26803A (xx)
ES (1) ES2221385T3 (xx)
GT (1) GT199900069A (xx)
HK (1) HK1036586A1 (xx)
HN (1) HN1999000072A (xx)
HU (1) HU228771B1 (xx)
ID (1) ID27724A (xx)
IL (2) IL139298A0 (xx)
IS (1) IS2233B (xx)
MY (1) MY157878A (xx)
NO (1) NO328959B1 (xx)
NZ (1) NZ508015A (xx)
PA (1) PA8472801A1 (xx)
PE (1) PE20000556A1 (xx)
PL (1) PL204921B1 (xx)
PT (1) PT1077692E (xx)
SI (1) SI1077692T1 (xx)
SV (1) SV1999000064A (xx)
TW (1) TWI243054B (xx)
UY (1) UY25512A1 (xx)
WO (1) WO1999059573A1 (xx)
ZA (1) ZA200006484B (xx)

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DE60101476T2 (de) * 2000-06-16 2004-05-27 Teva Pharmaceutical Industries Ltd. Stabiles gabapentin, das mehr als 20 ppm chlor enthält
PL363155A1 (en) * 2000-06-16 2004-11-15 Teva Pharmaceutical Industries, Ltd. Stable gabapentin having ph within a controlled range
US7056951B2 (en) * 2000-09-26 2006-06-06 Mutual Pharmaceutical Co., Inc. Stable solid dosage forms of amino acids and processes for producing same
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WO2007107835A2 (en) * 2006-03-17 2007-09-27 Aurobindo Pharma Limited Stable liquid formulations of antiepileptic agents
DE102007019071A1 (de) 2007-04-23 2008-10-30 Ratiopharm Gmbh Stabilisierte pharmazeutische Zusammensetzung enthaltend Pregabalin
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JP2010043063A (ja) * 2008-05-09 2010-02-25 Agency For Science Technology & Research 川崎病の診断及び治療
MX364974B (es) 2009-05-19 2019-05-16 Neuroderm Ltd Composiciones para la administracion continua de inhibidores de dopa descarboxilasa.
HU230031B1 (hu) 2010-03-01 2015-05-28 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság Pregabalint és izomaltot tartalmazó stabilizált gyógyszerkészítmény
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EP2389933A1 (en) 2010-05-25 2011-11-30 Sanovel Ilac Sanayi ve Ticaret A.S. Controlled-Release Pregabalin Compositions
EP2389934A1 (en) 2010-05-25 2011-11-30 Sanovel Ilac Sanayi ve Ticaret A.S. Controlled-Release Tablet Formulations of Pregabalin
WO2012066538A1 (en) 2010-11-15 2012-05-24 Neuroderm Ltd Continuous administration of l-dopa, dopa decarboxylase inhibitors, catechol-o-methyl transferase inhibitors and compositions for same
EP3456315A1 (en) 2012-06-05 2019-03-20 Neuroderm Ltd Compositions comprising apomorphine and organic acids and uses thereof
CN103494796B (zh) * 2013-09-30 2016-01-20 浙江华义医药有限公司 普瑞巴林稳定的药物组合物及其制备方法
US20160338949A1 (en) 2014-01-28 2016-11-24 Sun Pharmaceutical Industries Limited Stabilized gastroretentive tablets of pregabalin
US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
RS65060B1 (sr) 2014-03-13 2024-02-29 Neuroderm Ltd Sastavi inhibitora dopa dekarboksilaze
EP2923694B1 (en) * 2014-03-27 2018-11-14 Sanovel Ilac Sanayi ve Ticaret A.S. Oral liquid pharmaceutical solution of gabapentin
MA39272A (fr) * 2014-04-09 2015-10-14 Arven Ilac Sanayi Ve Ticaret As Formulations à libération prolongée de gabapentine
US10561602B2 (en) 2015-05-26 2020-02-18 Isa Odidi Controlled extended release pregabalin
JP6919119B2 (ja) * 2017-01-23 2021-08-18 日新製薬株式会社 ３位が置換されたγ−アミノ酪酸誘導体を含有する圧縮固形医薬組成物。
CN113164423A (zh) 2018-10-04 2021-07-23 美德阿利克斯株式会社 用非水溶剂稳定化的制剂
US10792262B1 (en) * 2019-07-29 2020-10-06 Saol International Limited Stabilized formulations of 4-amino-3-substituted butanoic acid derivatives
US11654124B2 (en) 2019-07-29 2023-05-23 Amneal Pharmaceuticals Llc Stabilized formulations of 4-amino-3-substituted butanoic acid derivatives
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US11331293B1 (en) 2020-11-17 2022-05-17 Neuroderm, Ltd. Method for treatment of Parkinson's disease
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Also Published As

Publication number Publication date
CO5021224A1 (es) 2001-03-27
HK1036586A1 (en) 2002-01-11
ES2221385T3 (es) 2004-12-16
GT199900069A (es) 2000-11-04
CN1301155A (zh) 2001-06-27
WO1999059573A9 (en) 2000-05-04
IS2233B (is) 2007-04-15
ZA200006484B (en) 2002-02-11
KR100602047B1 (ko) 2006-07-19
MY157878A (en) 2016-07-29
HN1999000072A (es) 2000-06-05
PL344218A1 (en) 2001-10-08
CA2327285C (en) 2005-06-14
NO20005768L (no) 2000-11-14
KR20010043611A (ko) 2001-05-25
CR6026A (es) 2008-08-26
NO20005768D0 (no) 2000-11-14
SI1077692T1 (en) 2004-10-31
PT1077692E (pt) 2004-12-31
WO1999059573A1 (en) 1999-11-25
EG26803A (en) 2014-09-21
DK1077692T3 (da) 2004-12-06
HUP0102022A2 (hu) 2001-11-28
DE69918977T2 (de) 2005-07-28
TWI243054B (en) 2005-11-11
EP1077692B1 (en) 2004-07-28
BR9910508B1 (pt) 2012-01-24
SV1999000064A (es) 2000-03-31
AR020323A1 (es) 2002-05-08
ATE271864T1 (de) 2004-08-15
HUP0102022A3 (en) 2002-11-28
ID27724A (id) 2001-04-26
PE20000556A1 (es) 2000-08-10
AU4073599A (en) 1999-12-06
PL204921B1 (pl) 2010-02-26
EP1077692A1 (en) 2001-02-28
CN1303991C (zh) 2007-03-14
HU228771B1 (en) 2013-05-28
CU23253B7 (es) 2007-12-17
JP2000034226A (ja) 2000-02-02
IL139298A (en) 2009-07-20
NO328959B1 (no) 2010-06-28
US7309719B1 (en) 2007-12-18
NZ508015A (en) 2003-11-28
PA8472801A1 (es) 2001-12-14
CA2327285A1 (en) 1999-11-25
JP4612923B2 (ja) 2011-01-12
BR9910508A (pt) 2001-01-02
IS5666A (is) 2000-10-16
DE69918977D1 (de) 2004-09-02
AU768277B2 (en) 2003-12-04
UY25512A1 (es) 1999-07-19

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