CS61484A2 - Method of 4-cyanopyridazines preparation - Google Patents

Method of 4-cyanopyridazines preparation

Info

Publication number
CS61484A2
CS61484A2 CS84614A CS61484A CS61484A2 CS 61484 A2 CS61484 A2 CS 61484A2 CS 84614 A CS84614 A CS 84614A CS 61484 A CS61484 A CS 61484A CS 61484 A2 CS61484 A2 CS 61484A2
Authority
CS
Czechoslovakia
Prior art keywords
cyanopyridazines
preparation
cyanopyridazines preparation
Prior art date
Application number
CS84614A
Other languages
English (en)
Other versions
CS274405B2 (en
Inventor
Kathleen Biziere
Jean-Paul Kan
Camille-Georges Prof Wermuth
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8301366A external-priority patent/FR2540115B1/fr
Priority claimed from FR8318433A external-priority patent/FR2555178B1/fr
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of CS61484A2 publication Critical patent/CS61484A2/cs
Publication of CS274405B2 publication Critical patent/CS274405B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CS61484A 1983-01-28 1984-01-27 Method of 4-cyanopyridazines preparation CS274405B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8301366A FR2540115B1 (fr) 1983-01-28 1983-01-28 Derive de la pyridazine ayant une action psychotrope, son mode de preparation et les medicaments en contenant
FR8318433A FR2555178B1 (fr) 1983-11-18 1983-11-18 Derives cyanes de la pyridazine ayant une action psychotrope, leur mode de preparation et les medicaments en contenant

Publications (2)

Publication Number Publication Date
CS61484A2 true CS61484A2 (en) 1990-09-12
CS274405B2 CS274405B2 (en) 1991-04-11

Family

ID=26223263

Family Applications (1)

Application Number Title Priority Date Filing Date
CS61484A CS274405B2 (en) 1983-01-28 1984-01-27 Method of 4-cyanopyridazines preparation

Country Status (25)

Country Link
US (2) US4565814A (cs)
EP (1) EP0116494B1 (cs)
KR (1) KR910000639B1 (cs)
AU (1) AU566352B2 (cs)
CA (1) CA1218655A (cs)
CS (1) CS274405B2 (cs)
DD (1) DD215542A5 (cs)
DE (1) DE3469026D1 (cs)
DK (3) DK159969C (cs)
ES (1) ES529108A0 (cs)
FI (1) FI77453C (cs)
GR (1) GR81682B (cs)
HU (1) HU192975B (cs)
IE (1) IE56750B1 (cs)
IL (1) IL70755A (cs)
MA (1) MA20019A1 (cs)
NO (1) NO840329L (cs)
NZ (1) NZ206957A (cs)
OA (1) OA07645A (cs)
PH (1) PH21476A (cs)
PL (1) PL143994B1 (cs)
PT (1) PT77994B (cs)
SG (1) SG9389G (cs)
SU (1) SU1274623A3 (cs)
YU (1) YU14184A (cs)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2540113A1 (fr) * 1983-01-27 1984-08-03 Sanofi Sa Acides derives de la pyridazine actifs sur le systeme nerveux central
AU592574B2 (en) * 1985-06-14 1990-01-18 Eli Lilly And Company Fungicidal pyridazines
US5106973A (en) * 1987-11-23 1992-04-21 Janssen Pharmaceutica N.V. Pyridzainamine derivatives
AU756635B2 (en) 1998-08-20 2003-01-16 Toyama Chemical Co. Ltd. Nitrogenous heterocyclic carboxamide derivatives or salts thereof and antiviral agents containing both
JP4754693B2 (ja) 1999-01-22 2011-08-24 エラン ファーマシューティカルズ,インコーポレイテッド Vla−4関連障害を処置するアシル誘導体
TW200307671A (en) 2002-05-24 2003-12-16 Elan Pharm Inc Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins
TWI281470B (en) 2002-05-24 2007-05-21 Elan Pharm Inc Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins
US8338591B2 (en) * 2004-05-08 2012-12-25 Novartis International Pharmaceutical Ltd. 3-aryl-5,6-disubstituted pyridazines
EP1741709A1 (en) * 2005-06-28 2007-01-10 Sanofi-Aventis Deutschland GmbH Heteroaryl-substituted amides comprising a saturated linker group, and their use as pharmaceuticals
BRPI0616687A2 (pt) 2005-09-29 2011-06-28 Elan Pharm Inc compostos de pirimidinil amida que inibem a adesão leucocitária mediada por vla-4
DE602006020754D1 (de) 2005-09-29 2011-04-28 Elan Pharm Inc Carbamatverbindungen, die die durch vla-4 vermittelte leukozytenadhäsion inhibieren
US7579466B2 (en) 2006-02-27 2009-08-25 Elan Pharmaceuticals, Inc. Pyrimidinyl sulfonamide compounds which inhibit leukocyte adhesion mediated by VLA-4
JP2012525336A (ja) 2009-04-27 2012-10-22 エラン ファーマシューティカルズ,インコーポレイテッド α−4インテグリンのピリジノンアンタゴニスト
AR081331A1 (es) 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
WO2011133920A1 (en) 2010-04-23 2011-10-27 Cytokinetics, Inc. Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use
AR081626A1 (es) 2010-04-23 2012-10-10 Cytokinetics Inc Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1345880A (en) * 1971-06-18 1974-02-06 Cepbepe Pyridazine derivatives
FR2510998B1 (fr) * 1981-08-07 1986-01-10 Sanofi Sa Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent
FR2510997A1 (fr) * 1981-08-10 1983-02-11 Sanofi Sa Nouveaux derives de la methyl-4 phenyl-6 pyridazine, procede pour leur preparation et medicaments actifs sur le systeme nerveux central en contenant
FR2539739B1 (fr) * 1983-01-24 1985-11-22 Sanofi Sa Nouveaux derives de la naphtyl pyridazine actifs sur le systeme nerveux central, procede de preparation de ces derives et medicaments en contenant

Also Published As

Publication number Publication date
CS274405B2 (en) 1991-04-11
DK621689A (da) 1989-12-08
FI840349L (fi) 1984-07-29
GR81682B (cs) 1984-12-12
US4631280A (en) 1986-12-23
US4565814A (en) 1986-01-21
IE56750B1 (en) 1991-12-04
NO840329L (no) 1984-07-30
OA07645A (fr) 1985-05-23
NZ206957A (en) 1987-06-30
YU14184A (en) 1986-10-31
FI77453B (fi) 1988-11-30
PH21476A (en) 1987-10-28
DK621589D0 (da) 1989-12-08
IL70755A (en) 1987-03-31
CA1218655A (en) 1987-03-03
ES8500253A1 (es) 1984-10-01
KR840007587A (ko) 1984-12-08
DK162218C (da) 1992-03-02
DK162219C (da) 1992-03-02
HU192975B (en) 1987-08-28
EP0116494A1 (fr) 1984-08-22
DK25984A (da) 1984-07-29
AU566352B2 (en) 1987-10-15
IL70755A0 (en) 1984-04-30
KR910000639B1 (ko) 1991-01-31
PT77994A (fr) 1984-02-01
DE3469026D1 (en) 1988-03-03
IE840148L (en) 1984-07-28
DK621589A (da) 1989-12-08
PL143994B1 (en) 1988-04-30
SU1274623A3 (ru) 1986-11-30
MA20019A1 (fr) 1984-10-01
ES529108A0 (es) 1984-10-01
DK25984D0 (da) 1984-01-20
DK159969C (da) 1991-05-27
DD215542A5 (de) 1984-11-14
AU2372884A (en) 1984-08-02
SG9389G (en) 1989-07-07
FI840349A0 (fi) 1984-01-27
DK159969B (da) 1991-01-07
PT77994B (fr) 1986-04-10
DK621689D0 (da) 1989-12-08
DK162219B (da) 1991-09-30
EP0116494B1 (fr) 1988-01-27
PL245932A1 (en) 1985-05-21
DK162218B (da) 1991-09-30
FI77453C (fi) 1989-03-10

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