CS271343B2 - Method of new diphenylamine derivatives production - Google Patents
Method of new diphenylamine derivatives production Download PDFInfo
- Publication number
- CS271343B2 CS271343B2 CS875119A CS511987A CS271343B2 CS 271343 B2 CS271343 B2 CS 271343B2 CS 875119 A CS875119 A CS 875119A CS 511987 A CS511987 A CS 511987A CS 271343 B2 CS271343 B2 CS 271343B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- formula
- hydrogen
- compound
- compounds
- chlorine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/16—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/58—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU862873A HU200591B (en) | 1986-07-11 | 1986-07-11 | Process for producing new diphenyl propylamine derivatives and pharmaceutical compositions comprising such compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
CS511987A2 CS511987A2 (en) | 1989-08-14 |
CS271343B2 true CS271343B2 (en) | 1990-09-12 |
Family
ID=55982790
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS875119A CS271343B2 (en) | 1986-07-11 | 1987-07-06 | Method of new diphenylamine derivatives production |
Country Status (28)
Country | Link |
---|---|
US (1) | US4988730A (fr) |
EP (1) | EP0253327B1 (fr) |
JP (1) | JP2637737B2 (fr) |
KR (1) | KR910000864B1 (fr) |
CN (1) | CN1019571B (fr) |
AT (1) | ATE75722T1 (fr) |
AU (1) | AU599117B2 (fr) |
CA (1) | CA1335104C (fr) |
CS (1) | CS271343B2 (fr) |
DD (1) | DD263980A5 (fr) |
DE (1) | DE3778770D1 (fr) |
DK (1) | DK360187A (fr) |
ES (1) | ES2032778T3 (fr) |
FI (1) | FI95128C (fr) |
GR (1) | GR3004518T3 (fr) |
HR (1) | HRP930508A2 (fr) |
HU (1) | HU200591B (fr) |
IE (1) | IE60028B1 (fr) |
IL (1) | IL83044A (fr) |
NO (1) | NO167658C (fr) |
NZ (1) | NZ221036A (fr) |
PH (1) | PH24514A (fr) |
PL (1) | PL150887B1 (fr) |
PT (1) | PT85304B (fr) |
SI (1) | SI8711299A8 (fr) |
SU (2) | SU1597096A3 (fr) |
YU (1) | YU46559B (fr) |
ZA (1) | ZA874812B (fr) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1205124B (it) * | 1987-06-05 | 1989-03-15 | Simens Soteta Italiana Medicin | Composto attivo nella terapia carciovascolare |
GB8823203D0 (en) * | 1988-10-04 | 1988-11-09 | Pfizer Ltd | Therapeutic agents |
JPH04329415A (ja) * | 1991-04-30 | 1992-11-18 | Fujitsu Ltd | カード型入出力インタフェース装置及びシステム |
US5763569A (en) * | 1991-08-23 | 1998-06-09 | The Brigham And Women's Hospital, Inc | Calcium receptor-active molecules |
US5858684A (en) * | 1991-08-23 | 1999-01-12 | The Brigham And Women's Hospital, Inc. | Method of screening calcium receptor-active molecules |
ATE312347T1 (de) * | 1991-08-23 | 2005-12-15 | Nps Pharma Inc | Screening-verfahren für kalzium-rezeptor aktive verbindungen |
US5688938A (en) * | 1991-08-23 | 1997-11-18 | The Brigham & Women's Hospital, Inc. | Calcium receptor-active molecules |
US6011068A (en) * | 1991-08-23 | 2000-01-04 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US6001884A (en) * | 1991-08-23 | 1999-12-14 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US6313146B1 (en) | 1991-08-23 | 2001-11-06 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US6031003A (en) * | 1991-08-23 | 2000-02-29 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US5198548A (en) * | 1992-01-30 | 1993-03-30 | Warner-Lambert Company | Process for the preparation of D(-) and L(+)-3,3-diphenylalanine and D(-) and L(+)-substituted 3,3-diphenylalanines and derivatives thereof |
US6071970A (en) * | 1993-02-08 | 2000-06-06 | Nps Pharmaceuticals, Inc. | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
US5962314A (en) * | 1993-02-23 | 1999-10-05 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
RU2146132C1 (ru) * | 1993-02-23 | 2000-03-10 | Брихэм энд Уимен З Хоспитал, Инк. | Фармацевтическая композиция, активная в отношении рецептора кальция, способ лечения пациента, способ анализа соединения оказывать влияние на активность рецептора неорганического иона, нуклеиновая кислота, кодирующая рецептор, рецептор кальция |
US5492933A (en) * | 1993-10-08 | 1996-02-20 | Sepracor, Inc. | Methods and compositions for treating urinary incontinence and other disorders using optically pure R-terodiline and hydroxylated derivatives thereof |
PL183499B1 (pl) | 1994-10-21 | 2002-06-28 | Nps Pharma Inc | Związki do modulowania receptorów wapniowych i kompozycje farmaceutyczne |
DK0907631T3 (da) | 1996-05-01 | 2003-09-22 | Nps Pharma Inc | Uorganiske ionreceptoraktive forbindelser |
SE9701144D0 (sv) * | 1997-03-27 | 1997-03-27 | Pharmacia & Upjohn Ab | Novel compounds, their use and preparation |
US6124507A (en) | 1997-12-10 | 2000-09-26 | Union Carbide Chemicals & Plastics Technology Corporation | Electron donors |
EP0957073A1 (fr) * | 1998-05-12 | 1999-11-17 | Schwarz Pharma Ag | Dérivés de 3,3-diphénylpropylamines |
DE10315917A1 (de) * | 2003-04-08 | 2004-11-18 | Schwarz Pharma Ag | Hochreine Basen von 3,3-Diphenylpropylaminmonoestern |
FR2902789A1 (fr) * | 2006-06-21 | 2007-12-28 | Genfit Sa | Derives de 1,3-diphenylpropane substitues, preparations et utilisations |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1171930B (de) * | 1961-08-10 | 1964-06-11 | Chinoin Gyogyszer Es Vegyeszet | Verfahren zur Herstellung von koronardilatent wirksamen substituierten Propylaminderivaten |
CH462189A (de) * | 1961-08-10 | 1968-09-15 | Chinoin Gyogyszer Es Vegyeszet | Verfahren zur Herstellung von substituierten Propylaminderivaten |
GB1032650A (en) * | 1962-05-24 | 1966-06-15 | Chinoin Gyogyszer Es Vegyeszet | Improvements in or relating to diphenyl-propylamine derivatives |
DD122967A1 (de) * | 1975-07-10 | 1976-11-12 | Lothar Luecke | Hylamin-derivate |
-
1986
- 1986-07-11 HU HU862873A patent/HU200591B/hu not_active IP Right Cessation
-
1987
- 1987-07-01 IL IL83044A patent/IL83044A/xx unknown
- 1987-07-02 ZA ZA874812A patent/ZA874812B/xx unknown
- 1987-07-06 CS CS875119A patent/CS271343B2/cs unknown
- 1987-07-07 PH PH35508A patent/PH24514A/en unknown
- 1987-07-10 DK DK360187A patent/DK360187A/da not_active Application Discontinuation
- 1987-07-10 YU YU129987A patent/YU46559B/sh unknown
- 1987-07-10 PT PT85304A patent/PT85304B/pt not_active IP Right Cessation
- 1987-07-10 IE IE186687A patent/IE60028B1/en not_active IP Right Cessation
- 1987-07-10 PL PL1987266759A patent/PL150887B1/pl unknown
- 1987-07-10 FI FI873069A patent/FI95128C/fi not_active IP Right Cessation
- 1987-07-10 DE DE8787109989T patent/DE3778770D1/de not_active Expired - Fee Related
- 1987-07-10 NO NO872880A patent/NO167658C/no unknown
- 1987-07-10 SU SU874202957A patent/SU1597096A3/ru active
- 1987-07-10 CA CA000541775A patent/CA1335104C/fr not_active Expired - Fee Related
- 1987-07-10 DD DD87304844A patent/DD263980A5/de not_active IP Right Cessation
- 1987-07-10 EP EP87109989A patent/EP0253327B1/fr not_active Expired - Lifetime
- 1987-07-10 AT AT87109989T patent/ATE75722T1/de not_active IP Right Cessation
- 1987-07-10 ES ES198787109989T patent/ES2032778T3/es not_active Expired - Lifetime
- 1987-07-10 JP JP62172731A patent/JP2637737B2/ja not_active Expired - Lifetime
- 1987-07-10 AU AU75526/87A patent/AU599117B2/en not_active Ceased
- 1987-07-10 SI SI8711299A patent/SI8711299A8/sl unknown
- 1987-07-10 NZ NZ221036A patent/NZ221036A/xx unknown
- 1987-07-11 KR KR1019870007467A patent/KR910000864B1/ko not_active IP Right Cessation
- 1987-07-11 CN CN87104753A patent/CN1019571B/zh not_active Expired
-
1988
- 1988-01-25 SU SU884355073A patent/SU1588740A1/ru active
-
1989
- 1989-07-21 US US07/385,539 patent/US4988730A/en not_active Expired - Fee Related
-
1992
- 1992-05-07 GR GR920400801T patent/GR3004518T3/el unknown
-
1993
- 1993-03-24 HR HR930508A patent/HRP930508A2/hr not_active Application Discontinuation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CS271343B2 (en) | Method of new diphenylamine derivatives production | |
EP0178874B1 (fr) | Alkylsulfonamidophénylalkylamines | |
LV12258B (en) | DIAMINOCYCLOBUTE-3,4-DIONES AS GLUDO MUSCULAR RELAXATION | |
FR2504920A1 (fr) | Derives phenylcyclobutyliques, leur procede de preparation et leur application therapeutique | |
DE69119013T2 (de) | Benzen-, Pyridin-, Pyrimidinderivat | |
FR2533924A1 (fr) | Nouveaux derives du 4-(1h-indol-3-yl)a-methyl piperidine-1-ethanol, leurs sels, le procede de preparation, l'application a titre de medicaments et les compositions les renfermant | |
CH631162A5 (fr) | Derives de la pyrrolidine, leur procede de preparation et leur application en therapeutique. | |
JPS6215062B2 (fr) | ||
US4596827A (en) | Alkylsulfonamidophenylalkylamine compounds used for treating arrhythmia | |
FI73206C (fi) | Foerfarande foer framstaellning av terapeutiskt anvaendbara alkyltiofenoxipropylaminer. | |
NO883070L (no) | 4-amino-substituerte 1,2-dihydroksynaftalin-derivater. | |
IE49549B1 (en) | Piperazine derivatives | |
JPS58116434A (ja) | 置換されたフエノキシアルカノ−ルアミン類及びフエノキシアルカノ−ル−シクロアルキルアミン類 | |
US4000192A (en) | Pharmacologically active compounds | |
EP0339878A2 (fr) | Dérivés de la propanamine | |
CS203057B2 (en) | Method of producing novel derivatives of n-/3,3-diphenyl propyl/-propylendiamine | |
EP0027679B1 (fr) | Composés substitués du 5 ((-7-chloro-4-quinoléinyl)amino)-3-(aminométhyl)-(1,1'-biphényl)-2-ol; procédé pour leur préparation; et compositions pharmaceutiques les contenant | |
US4101579A (en) | Phenethanolamine ethers | |
JPS6252740B2 (fr) | ||
EP0157762B1 (fr) | Nouvelles piperidinoguanidines substituees, leur procede de preparation et les compositions pharmaceutiques en renfermant | |
US4727180A (en) | Antihypertensive polyhalohydroxylisopropyl phenylalkanoic and phenylalkenoic acids, amides and esters and intermediates thereto | |
JPS6140247A (ja) | フエニルエチルアミノプロピオフエノン誘導体 | |
US3547974A (en) | Aromatic propylamino cyano compounds | |
KR840001077B1 (ko) | N⁴-카르바모일 피페라지노 프로판올 유도체의 제조방법 | |
CS208458B2 (en) | Method of making the now 1,4-cyclalkanoxazepines |