CS266593B2 - Method of 2-(2-hydroxy-3-phenosypropylamine) ethoxyphenolh's derivativesprodduction - Google Patents

Method of 2-(2-hydroxy-3-phenosypropylamine) ethoxyphenolh's derivativesprodduction Download PDF

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Publication number
CS266593B2
CS266593B2 CS865735A CS573586A CS266593B2 CS 266593 B2 CS266593 B2 CS 266593B2 CS 865735 A CS865735 A CS 865735A CS 573586 A CS573586 A CS 573586A CS 266593 B2 CS266593 B2 CS 266593B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
group
hydroxy
amino
pharmaceutically acceptable
Prior art date
Application number
CS865735A
Other languages
Czech (cs)
English (en)
Other versions
CS573586A2 (en
Inventor
Brian R Holloway
Ralph Howe
Balbir Singh Rao
Donald Stribling
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Publication of CS573586A2 publication Critical patent/CS573586A2/cs
Publication of CS266593B2 publication Critical patent/CS266593B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
CS865735A 1985-07-30 1986-07-30 Method of 2-(2-hydroxy-3-phenosypropylamine) ethoxyphenolh's derivativesprodduction CS266593B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858519154A GB8519154D0 (en) 1985-07-30 1985-07-30 Aromatic ethers

Publications (2)

Publication Number Publication Date
CS573586A2 CS573586A2 (en) 1989-04-14
CS266593B2 true CS266593B2 (en) 1990-01-12

Family

ID=10583042

Family Applications (1)

Application Number Title Priority Date Filing Date
CS865735A CS266593B2 (en) 1985-07-30 1986-07-30 Method of 2-(2-hydroxy-3-phenosypropylamine) ethoxyphenolh's derivativesprodduction

Country Status (27)

Country Link
US (1) US4772631A (de)
EP (1) EP0210849B1 (de)
JP (2) JPH0651661B2 (de)
KR (1) KR870001142A (de)
CN (1) CN1014516B (de)
AR (1) AR242176A1 (de)
AT (1) ATE55980T1 (de)
AU (1) AU603987B2 (de)
CA (1) CA1283122C (de)
CS (1) CS266593B2 (de)
DD (1) DD251551A5 (de)
DE (1) DE3673722D1 (de)
DK (1) DK168761B1 (de)
ES (1) ES2002720A6 (de)
FI (1) FI88030C (de)
GB (1) GB8519154D0 (de)
GR (1) GR861994B (de)
HU (1) HUT44757A (de)
IE (1) IE60157B1 (de)
IL (1) IL79447A0 (de)
NO (1) NO170480C (de)
NZ (1) NZ217011A (de)
PH (1) PH22503A (de)
PL (1) PL152320B1 (de)
PT (1) PT83085B (de)
SU (1) SU1632370A3 (de)
ZA (1) ZA865097B (de)

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EP0300290B1 (de) * 1987-07-21 1991-12-18 F. Hoffmann-La Roche Ag Phenoxypropanolamine
GB8801306D0 (en) * 1988-01-21 1988-02-17 Ici Plc Chemical compounds
GB8905336D0 (en) * 1989-03-08 1989-04-19 Ici Plc Chemical compounds
GB8910374D0 (en) * 1989-05-05 1989-06-21 Ici Plc Chemical compounds
KR920005952B1 (ko) * 1989-05-26 1992-07-25 이사무 이와이 오수정화조의 여과재 순환 정화장치
GB8925032D0 (en) * 1989-11-06 1989-12-28 Ici Plc Chemical compounds
GB8926083D0 (en) * 1989-11-17 1990-01-10 Ici Plc Therapeutic agents
GB9003185D0 (en) * 1990-02-13 1990-04-11 Ici Plc Pharmaceutical compositions
US5106867A (en) * 1990-05-04 1992-04-21 American Cyanamid Company Method of increasing lean meat in edible animals
US5151439A (en) * 1990-05-04 1992-09-29 American Cyanamid Company Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles
US5061727A (en) * 1990-05-04 1991-10-29 American Cyanamid Company Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles
US5245053A (en) * 1990-05-04 1993-09-14 American Cyanamid Company Substituted 5-(2-(2-aryl-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxoles
GB9016655D0 (en) * 1990-07-30 1990-09-12 Ici Plc Therapeutic agents
GB9111425D0 (en) * 1991-05-28 1991-07-17 Ici Plc Chemical compounds
GB9111426D0 (en) * 1991-05-28 1991-07-17 Ici Plc Chemical compounds
US5502078A (en) * 1991-05-28 1996-03-26 Zeneca Limited Chemical compounds
GB9224740D0 (en) * 1992-11-26 1993-01-13 Ici Plc Therapeutic agents
US5578638A (en) * 1993-11-05 1996-11-26 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists
US5563171A (en) * 1993-11-05 1996-10-08 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists
US5776983A (en) * 1993-12-21 1998-07-07 Bristol-Myers Squibb Company Catecholamine surrogates useful as β3 agonists
US5488064A (en) * 1994-05-02 1996-01-30 Bristol-Myers Squibb Company Benzo 1,3 dioxole derivatives
US5491134A (en) * 1994-09-16 1996-02-13 Bristol-Myers Squibb Company Sulfonic, phosphonic or phosphiniic acid β3 agonist derivatives
US5541204A (en) * 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
ZA967892B (en) * 1995-09-21 1998-03-18 Lilly Co Eli Selective β3 adrenergic agonists.
US6075040A (en) 1996-09-05 2000-06-13 Eli Lilly And Company Selective β3 adrenergic agonists
US5770615A (en) * 1996-04-04 1998-06-23 Bristol-Myers Squibb Company Catecholamine surrogates useful as β3 agonists
ATE215369T1 (de) 1996-09-05 2002-04-15 Lilly Co Eli Carbazolanaloge als selektive beta3-adrenergische agonisten
CO5011072A1 (es) 1997-12-05 2001-02-28 Lilly Co Eli Etanolaminas pirazinil substituidas como agfonistas de los receptores
GB9812709D0 (en) * 1998-06-13 1998-08-12 Glaxo Group Ltd Chemical compounds
US6344481B1 (en) 1999-03-01 2002-02-05 Pfizer Inc. Thyromimetic antiobesity agents
US7504435B2 (en) * 2001-01-31 2009-03-17 The Arizona Board Of Regents On Behalf Of The University Of Arizona Method for stimulating weight loss and/or for lowering triglycerides in patients
US7709677B2 (en) * 2001-01-31 2010-05-04 Glaxosmithkline Llc Process of preparing arylethanoldiamines
GB0102407D0 (en) 2001-01-31 2001-03-14 Glaxo Group Ltd Process
US7202222B2 (en) * 2003-01-06 2007-04-10 National Bioscience Corporation Methods for treatment of obesity and effective fat loss promotion
WO2008106213A1 (en) * 2007-02-27 2008-09-04 Titan Pharmaceuticals, Inc. Administration of 3,5-diiodothyropropionic acid for stimulating weight loss, and/or lowering triglyceride levels, and/or treatment of metabolic syndrome.
US9044606B2 (en) 2010-01-22 2015-06-02 Ethicon Endo-Surgery, Inc. Methods and devices for activating brown adipose tissue using electrical energy
US8476227B2 (en) 2010-01-22 2013-07-02 Ethicon Endo-Surgery, Inc. Methods of activating a melanocortin-4 receptor pathway in obese subjects
US9522129B2 (en) 2010-08-03 2016-12-20 Velicept Therapeutics, Inc. Pharmaceutical Combination
US9907767B2 (en) 2010-08-03 2018-03-06 Velicept Therapeutics, Inc. Pharmaceutical compositions and the treatment of overactive bladder
CA2866080C (en) * 2012-03-01 2021-01-19 University Of Cincinnati Ros-activated compounds as selective anti-cancer therapeutics
KR20170086659A (ko) 2014-12-03 2017-07-26 벨리셉트 테라퓨틱스, 인크. 하부 요로 증상을 위한 변형 방출형 솔라베그론을 이용한 조성물 및 방법
US10092738B2 (en) 2014-12-29 2018-10-09 Ethicon Llc Methods and devices for inhibiting nerves when activating brown adipose tissue
US10080884B2 (en) 2014-12-29 2018-09-25 Ethicon Llc Methods and devices for activating brown adipose tissue using electrical energy
FI3365321T3 (fi) 2015-10-23 2024-01-02 B3Ar Therapeutics Inc Solabegron-Zwitterioni ja sen käyttöjä

Family Cites Families (14)

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Publication number Priority date Publication date Assignee Title
GB1245148A (en) * 1968-11-18 1971-09-08 Pfizer Ltd Propanolamine derivatives
DE1957706C3 (de) * 1968-11-18 1978-06-29 Pfizer Corp., Colon (Panama) Kernsubstituierte 3-Phenoxy-l-phenoxyalkylamino-propan-2-ole und Arzneimittel auf deren Basis
SE354851B (de) * 1970-02-18 1973-03-26 Haessle Ab
US4146638A (en) * 1976-02-17 1979-03-27 Boehringer Ingelheim Gmbh N-(3-phenoxy-2-hydroxy-propyl)-n-(2-phenyl-2-hydroxy-ethyl)-amines
US4191765A (en) * 1976-05-25 1980-03-04 Hoechst Aktiengesellschaft 1-Aryloxy-2-hydroxy-3-aminopropanes
CH632987A5 (en) * 1976-10-07 1982-11-15 Haessle Ab Process for preparing novel amines
SE416545B (sv) * 1976-10-07 1981-01-19 Haessle Ab Forfarande for framstellning av nya hjertaktiva 1-frnoxi-3-aminopropan-2-ol-derivat
EP0006735B1 (de) * 1978-06-28 1983-06-15 Beecham Group Plc Sekundäre Amine, ihre Herstellung, pharmazeutische Zusammensetzungen, die sie enthalten, und deren Verwendung
SE7807408L (sv) * 1978-06-30 1979-12-31 Haessle Ab Hjertaktiva foreningar
ATE1994T1 (de) * 1979-06-16 1982-12-15 Beecham Group Plc Aethanamin-derivate, ihre herstellung und verwendung in pharmazeutischen zusammensetzungen.
ATE2265T1 (de) * 1979-10-25 1983-02-15 Beecham Group Plc Sekundaere amine, ihre herstellung und verwendung in pharmazeutischen zusammensetzungen.
IL65541A0 (en) * 1981-05-06 1982-07-30 Haessle Ab Alkylamino-2-propanols,process for their preparation and pharmaceutical preparations containing same
GB8415377D0 (en) * 1984-06-15 1984-07-18 Beecham Group Plc Compounds
GB8510146D0 (en) * 1985-04-20 1985-05-30 Smith Kline French Lab Chemical compounds & processes

Also Published As

Publication number Publication date
KR870001142A (ko) 1987-03-11
ES2002720A6 (es) 1988-10-01
GR861994B (en) 1986-11-26
NZ217011A (en) 1990-02-26
NO863061D0 (no) 1986-07-29
PT83085B (pt) 1989-01-30
DD251551A5 (de) 1987-11-18
IL79447A0 (en) 1986-10-31
PH22503A (en) 1988-09-12
NO863061L (no) 1987-02-02
IE60157B1 (en) 1994-06-15
CN86105400A (zh) 1987-03-11
AU603987B2 (en) 1990-12-06
FI88030B (fi) 1992-12-15
SU1632370A3 (ru) 1991-02-28
JPH06340597A (ja) 1994-12-13
DE3673722D1 (en) 1990-10-04
JPH0651661B2 (ja) 1994-07-06
AU6002986A (en) 1987-02-05
US4772631A (en) 1988-09-20
FI862896A (fi) 1987-01-31
EP0210849A1 (de) 1987-02-04
AR242176A1 (es) 1993-03-31
JPH0819062B2 (ja) 1996-02-28
NO170480C (no) 1992-10-21
GB8519154D0 (en) 1985-09-04
HUT44757A (en) 1988-04-28
CS573586A2 (en) 1989-04-14
ATE55980T1 (de) 1990-09-15
JPS6277357A (ja) 1987-04-09
DK359986D0 (da) 1986-07-29
IE861827L (en) 1987-01-30
FI862896A0 (fi) 1986-07-09
PL152320B1 (en) 1990-12-31
PL260759A1 (en) 1988-09-15
FI88030C (fi) 1993-03-25
PT83085A (en) 1986-08-01
NO170480B (no) 1992-07-13
DK359986A (da) 1987-01-31
EP0210849B1 (de) 1990-08-29
DK168761B1 (da) 1994-06-06
CA1283122C (en) 1991-04-16
ZA865097B (en) 1987-03-25
CN1014516B (zh) 1991-10-30

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