CS264349B2 - Process for preparing new derivatives of 1h,3h-pyrrolo-/1,2-c/thiazole - Google Patents

Process for preparing new derivatives of 1h,3h-pyrrolo-/1,2-c/thiazole Download PDF

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Publication number
CS264349B2
CS264349B2 CS875014A CS501487A CS264349B2 CS 264349 B2 CS264349 B2 CS 264349B2 CS 875014 A CS875014 A CS 875014A CS 501487 A CS501487 A CS 501487A CS 264349 B2 CS264349 B2 CS 264349B2
Authority
CS
Czechoslovakia
Prior art keywords
total
pyridyl
pyrrolo
temperature
solution
Prior art date
Application number
CS875014A
Other languages
Czech (cs)
English (en)
Other versions
CS501487A2 (en
Inventor
Jean-Louis Fabre
Claude James
Daniel Lave
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of CS501487A2 publication Critical patent/CS501487A2/cs
Publication of CS264349B2 publication Critical patent/CS264349B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Photoreceptors In Electrophotography (AREA)
CS875014A 1986-07-04 1987-07-02 Process for preparing new derivatives of 1h,3h-pyrrolo-/1,2-c/thiazole CS264349B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8609729A FR2601016B1 (fr) 1986-07-04 1986-07-04 Nouveaux derives du 1h,3h-pyrrolo (1,2-c) thiazole, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
CS501487A2 CS501487A2 (en) 1988-11-15
CS264349B2 true CS264349B2 (en) 1989-07-12

Family

ID=9337076

Family Applications (1)

Application Number Title Priority Date Filing Date
CS875014A CS264349B2 (en) 1986-07-04 1987-07-02 Process for preparing new derivatives of 1h,3h-pyrrolo-/1,2-c/thiazole

Country Status (28)

Country Link
US (1) US4786645A (pt)
EP (1) EP0252823B1 (pt)
JP (1) JP2517725B2 (pt)
KR (1) KR950012680B1 (pt)
AT (1) ATE54454T1 (pt)
AU (1) AU598560B2 (pt)
BG (1) BG47037A3 (pt)
CA (1) CA1294967C (pt)
CS (1) CS264349B2 (pt)
DD (1) DD263774A5 (pt)
DE (1) DE3763630D1 (pt)
DK (1) DK340187A (pt)
ES (1) ES2016375B3 (pt)
FI (1) FI84728C (pt)
FR (1) FR2601016B1 (pt)
GR (1) GR3000637T3 (pt)
HU (1) HU196414B (pt)
IE (1) IE60772B1 (pt)
IL (1) IL83067A (pt)
MA (1) MA21028A1 (pt)
MX (1) MX173699B (pt)
NO (1) NO170583C (pt)
NZ (1) NZ220930A (pt)
PL (1) PL150646B1 (pt)
PT (1) PT85236B (pt)
SU (1) SU1510719A3 (pt)
TN (1) TNSN87084A1 (pt)
ZA (1) ZA874815B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601015B1 (fr) * 1986-07-04 1988-08-05 Rhone Poulenc Sante Nouveaux derives du 1h,3h-pyrrolo (1,2-c) thiazole, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2617484B1 (fr) * 1987-07-02 1989-10-20 Rhone Poulenc Sante Procede de preparation de l'acide (pyridyl-3)-3 1h-3h-pyrrolo (1,2-c) thiazolecarboxylique-7 dextrogyre
FR2626004B1 (fr) * 1988-01-20 1991-08-02 Rhone Poulenc Sante Procede de preparation du (pyridyl-3)-3 1h, 3h-pyrrolo (1,2-c) thiazolecarbonitrile-7
FR2644456B1 (fr) * 1989-03-17 1991-07-05 Rhone Poulenc Sante Nouveaux derives du 1h, 3h-pyrrolo(1,2-c)thiazolecarboxamide-7, leur preparation et les compositions pharmaceutiques qui les contiennent
US5260451A (en) * 1989-05-11 1993-11-09 Merckle Gmbh Substituted pyrrole compounds and use thereof in pharmaceutical compositions
DE3915450A1 (de) * 1989-05-11 1990-11-15 Gerd Prof Dr Dannhardt Substituierte pyrrolverbindungen und deren anwendung in der pharmazie
JP3061631B2 (ja) * 1989-10-11 2000-07-10 山之内製薬株式会社 新規なヘテロ環化合物およびその製造法
US5120749A (en) * 1991-02-20 1992-06-09 Abbott Laboratories Platelet activating antagonists
US5120751A (en) * 1991-03-29 1992-06-09 Abbott Laboratories Benzoylphenyl pyridinylthiazolidine compounds as platelet activating antagonists
US5149704A (en) * 1991-05-03 1992-09-22 Abbott Laboratories Platelet activating antagonists
US5639782A (en) * 1992-03-04 1997-06-17 Center For Innovative Technology Neolignan derivatives as platelet activating factor receptor antagonists and 5-lipoxygenase inhibitors
US5530141A (en) * 1992-03-04 1996-06-25 Center For Innovative Technology 2,4-diaryl-1,3-dithiolanes; 2,4-diaryl-1,3-dioxolanes; 2,4-diaryl-1,3-oxathiolanes; and 2,5-diaryl-1,3-oxathiolanes for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
US5463083A (en) * 1992-07-13 1995-10-31 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5434151A (en) * 1992-08-24 1995-07-18 Cytomed, Inc. Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
US5358938A (en) * 1992-07-13 1994-10-25 Cytomed, Inc. Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
US5648486A (en) * 1992-07-13 1997-07-15 Cytomed, Inc. Compounds and methods for the treatment of inflammatory and immune disorders
WO1994001430A1 (en) 1992-07-13 1994-01-20 Cytomed, Inc. 2,5-diaryl tetrahydro-thiophenes, -furans and analogs for the treatment of inflammatory and immune disorders
US5703093A (en) * 1995-05-31 1997-12-30 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5792776A (en) * 1994-06-27 1998-08-11 Cytomed, Inc., Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5750565A (en) 1995-05-25 1998-05-12 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2541280B1 (fr) * 1983-01-13 1985-06-21 Rhone Poulenc Sante Nouveaux derives du 1h, 3h-pyrrolo (1,2c) thiazolecarboxamide-7, leur preparation et les medicaments qui les contiennent
FR2601015B1 (fr) * 1986-07-04 1988-08-05 Rhone Poulenc Sante Nouveaux derives du 1h,3h-pyrrolo (1,2-c) thiazole, leur preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
US4786645A (en) 1988-11-22
NZ220930A (en) 1989-10-27
NO872780D0 (no) 1987-07-02
EP0252823A1 (fr) 1988-01-13
AU7504187A (en) 1988-01-07
AU598560B2 (en) 1990-06-28
IL83067A0 (en) 1987-12-31
PL150646B1 (en) 1990-06-30
HU196414B (en) 1988-11-28
TNSN87084A1 (fr) 1990-01-01
BG47037A3 (en) 1990-04-16
CA1294967C (fr) 1992-01-28
ES2016375B3 (es) 1990-11-01
DD263774A5 (de) 1989-01-11
FI84728B (fi) 1991-09-30
SU1510719A3 (ru) 1989-09-23
ZA874815B (en) 1988-03-30
ATE54454T1 (de) 1990-07-15
NO170583B (no) 1992-07-27
DK340187A (da) 1988-01-05
HUT44790A (en) 1988-04-28
DK340187D0 (da) 1987-07-02
FI872932A (fi) 1988-01-05
PT85236B (pt) 1990-03-30
IE871768L (en) 1988-01-04
JPS6322588A (ja) 1988-01-30
NO170583C (no) 1992-11-04
FR2601016A1 (fr) 1988-01-08
IE60772B1 (en) 1994-08-10
PT85236A (fr) 1987-08-01
DE3763630D1 (de) 1990-08-16
PL266581A1 (en) 1988-09-01
CS501487A2 (en) 1988-11-15
FI84728C (fi) 1992-01-10
EP0252823B1 (fr) 1990-07-11
NO872780L (no) 1988-01-05
MA21028A1 (fr) 1988-04-01
KR880001680A (ko) 1988-04-26
MX7190A (es) 1993-10-01
IL83067A (en) 1991-01-31
KR950012680B1 (ko) 1995-10-20
JP2517725B2 (ja) 1996-07-24
FR2601016B1 (fr) 1988-10-07
FI872932A0 (fi) 1987-07-02
MX173699B (es) 1994-03-23
GR3000637T3 (en) 1991-09-27

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