CS257791B2 - Method of eburnamenine's racemic and optically active derivatives' transstereoisomers production - Google Patents

Method of eburnamenine's racemic and optically active derivatives' transstereoisomers production Download PDF

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Publication number
CS257791B2
CS257791B2 CS862862A CS286286A CS257791B2 CS 257791 B2 CS257791 B2 CS 257791B2 CS 862862 A CS862862 A CS 862862A CS 286286 A CS286286 A CS 286286A CS 257791 B2 CS257791 B2 CS 257791B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
filtered
dihydro
compounds
chloroform
Prior art date
Application number
CS862862A
Other languages
Czech (cs)
English (en)
Inventor
Janos Kreidl
Gyoergy Visky
Laszlo Czibula
Bela Stefko
Maria Farkas
Zsolt Szombathelyi
Egon Karpati
Bela Kiss
Katalin Csomor
Laszlo Szporny
Lilla Forgacs
Csaba Kuthi
Aniko Gere
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of CS257791B2 publication Critical patent/CS257791B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
CS862862A 1985-04-19 1986-04-18 Method of eburnamenine's racemic and optically active derivatives' transstereoisomers production CS257791B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU851516A HU198207B (en) 1985-04-19 1985-04-19 Process for production of derivatives of eburnamenin and medical compositions containing them

Publications (1)

Publication Number Publication Date
CS257791B2 true CS257791B2 (en) 1988-06-15

Family

ID=10954833

Family Applications (1)

Application Number Title Priority Date Filing Date
CS862862A CS257791B2 (en) 1985-04-19 1986-04-18 Method of eburnamenine's racemic and optically active derivatives' transstereoisomers production

Country Status (32)

Country Link
US (1) US4839362A (sv)
JP (1) JPS61249982A (sv)
KR (1) KR860008175A (sv)
CN (1) CN1017429B (sv)
AR (1) AR242386A1 (sv)
AU (1) AU585973B2 (sv)
BE (1) BE904619A (sv)
CA (1) CA1314286C (sv)
CH (1) CH670449A5 (sv)
CS (1) CS257791B2 (sv)
DD (1) DD244555A5 (sv)
DE (1) DE3613199A1 (sv)
DK (1) DK179886A (sv)
ES (1) ES8801259A1 (sv)
FI (1) FI84352C (sv)
FR (1) FR2580647B1 (sv)
GB (1) GB2174092B (sv)
GR (1) GR861026B (sv)
HU (1) HU198207B (sv)
IL (1) IL78534A0 (sv)
IN (1) IN163020B (sv)
IT (1) IT1189462B (sv)
NL (1) NL8600987A (sv)
NO (1) NO861538L (sv)
NZ (1) NZ215881A (sv)
PH (1) PH22427A (sv)
PL (1) PL149331B1 (sv)
PT (1) PT82423B (sv)
SE (1) SE462684B (sv)
SU (1) SU1443801A3 (sv)
YU (1) YU46003B (sv)
ZA (1) ZA862937B (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2623501B1 (fr) * 1987-11-19 1990-03-16 Roussel Uclaf Nouveaux derives substitues de 20,21-dinoreburnamenine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions pharmaceutiques les renfermant
JPH02167279A (ja) * 1988-09-30 1990-06-27 Taisho Pharmaceut Co Ltd アポビンカミン酸誘導体

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2035784A1 (en) * 1969-03-27 1970-12-24 Olivier Louisette Vincamine derivs with therapeutic propert- - ies
FR2211004A5 (sv) * 1972-12-15 1974-07-12 Synthelabo
FR2259612B1 (sv) * 1974-01-31 1977-09-09 Synthelabo
FR2285390A1 (fr) * 1974-09-19 1976-04-16 Synthelabo Nouvelle methode de preparation du desoxyvincaminate d'hydroxy-2 propyle
HU171163B (hu) * 1974-09-27 1977-11-28 Richter Gedeon Vegyeszet Sposob poluchenija proizvodnykh trans eburnamenina
FR2299033A2 (fr) * 1975-01-31 1976-08-27 Synthelabo Esters de
HU170888B (hu) * 1975-06-10 1977-09-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh, opticheski aktivnykh proizvodnykh eburnameninov
HU171663B (hu) * 1975-09-01 1978-02-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh 14-skobka-zamehhennogo metil-skobka zakryta-vinkana
DE2703920A1 (de) * 1976-02-05 1977-08-11 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
GB1572189A (en) * 1976-09-03 1980-07-23 Buzas Andre 14 - alkoxycarbonyl - 3,4 - dehydro - 14,15 - dihydro-14,16 - eburnamenine perchlorates and their use to prepare stereoisomers of dihydro apovincaminic acid esters
AU532001B2 (en) * 1978-11-20 1983-09-15 Sumitomo Chemical Company, Limited Polycyclic indole derivatives
HU186891B (en) * 1981-06-12 1985-10-28 Richter Gedeon Vegyeszet Process for producing esters of apovincaminic acid

Also Published As

Publication number Publication date
IL78534A0 (en) 1986-08-31
DD244555A5 (de) 1987-04-08
GR861026B (en) 1986-08-11
GB8609532D0 (en) 1986-05-21
BE904619A (fr) 1986-08-18
IT1189462B (it) 1988-02-04
GB2174092A (en) 1986-10-29
DK179886D0 (da) 1986-04-18
AR242386A1 (es) 1993-03-31
CN1017429B (zh) 1992-07-15
CH670449A5 (sv) 1989-06-15
IT8620135A0 (it) 1986-04-18
IN163020B (sv) 1988-07-30
FI861656A0 (fi) 1986-04-18
HU198207B (en) 1989-08-28
SE8601798L (sv) 1986-10-20
YU60386A (en) 1988-08-31
NO861538L (no) 1986-10-20
PL149331B1 (en) 1990-02-28
SU1443801A3 (ru) 1988-12-07
PH22427A (en) 1988-09-12
ES554136A0 (es) 1987-12-16
DE3613199A1 (de) 1986-10-23
NZ215881A (en) 1989-01-06
FI84352B (fi) 1991-08-15
CN86102655A (zh) 1987-02-04
YU46003B (sh) 1992-12-21
CA1314286C (en) 1993-03-09
AU585973B2 (en) 1989-06-29
ES8801259A1 (es) 1987-12-16
ZA862937B (en) 1986-12-30
JPS61249982A (ja) 1986-11-07
PT82423B (pt) 1988-03-03
GB2174092B (en) 1989-10-25
FI861656A (fi) 1986-10-20
IT8620135A1 (it) 1987-10-18
SE8601798D0 (sv) 1986-04-18
AU5638086A (en) 1986-10-23
FR2580647B1 (fr) 1990-04-20
DK179886A (da) 1986-10-20
US4839362A (en) 1989-06-13
SE462684B (sv) 1990-08-13
KR860008175A (ko) 1986-11-12
FR2580647A1 (fr) 1986-10-24
NL8600987A (nl) 1986-11-17
HUT40653A (en) 1987-01-28
FI84352C (sv) 1991-11-25
PT82423A (en) 1986-05-01

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