CS238637B2 - Production method of a rigid shaped article including in advance chosen amount unit of chemical compound - Google Patents
Production method of a rigid shaped article including in advance chosen amount unit of chemical compound Download PDFInfo
- Publication number
- CS238637B2 CS238637B2 CS828515A CS851582A CS238637B2 CS 238637 B2 CS238637 B2 CS 238637B2 CS 828515 A CS828515 A CS 828515A CS 851582 A CS851582 A CS 851582A CS 238637 B2 CS238637 B2 CS 238637B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- mold
- mixture
- chemical
- angle
- vertical
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title description 5
- 150000001875 compounds Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 claims abstract description 46
- 239000000126 substance Substances 0.000 claims abstract description 20
- 239000002552 dosage form Substances 0.000 claims abstract description 12
- 239000012876 carrier material Substances 0.000 claims abstract description 10
- 239000002904 solvent Substances 0.000 claims abstract description 10
- 239000007787 solid Substances 0.000 claims abstract description 8
- 238000000034 method Methods 0.000 claims description 19
- 108010010803 Gelatin Proteins 0.000 claims description 16
- 229920000159 gelatin Polymers 0.000 claims description 16
- 239000008273 gelatin Substances 0.000 claims description 16
- 235000019322 gelatine Nutrition 0.000 claims description 16
- 235000011852 gelatine desserts Nutrition 0.000 claims description 16
- 239000000463 material Substances 0.000 claims description 7
- 238000007710 freezing Methods 0.000 abstract description 5
- 230000008014 freezing Effects 0.000 abstract description 5
- 238000000859 sublimation Methods 0.000 abstract description 2
- 230000008022 sublimation Effects 0.000 abstract description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 239000004800 polyvinyl chloride Substances 0.000 description 7
- 229920000915 polyvinyl chloride Polymers 0.000 description 7
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 6
- ZORQXIQZAOLNGE-UHFFFAOYSA-N 1,1-difluorocyclohexane Chemical compound FC1(F)CCCCC1 ZORQXIQZAOLNGE-UHFFFAOYSA-N 0.000 description 5
- 229930195725 Mannitol Natural products 0.000 description 5
- 238000001035 drying Methods 0.000 description 5
- 239000010410 layer Substances 0.000 description 5
- 239000000594 mannitol Substances 0.000 description 5
- 235000010355 mannitol Nutrition 0.000 description 5
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 5
- 229920000053 polysorbate 80 Polymers 0.000 description 5
- 238000010438 heat treatment Methods 0.000 description 4
- SEOVTRFCIGRIMH-UHFFFAOYSA-N indole-3-acetic acid Chemical compound C1=CC=C2C(CC(=O)O)=CNC2=C1 SEOVTRFCIGRIMH-UHFFFAOYSA-N 0.000 description 4
- 239000000725 suspension Substances 0.000 description 4
- 229960004535 oxazepam Drugs 0.000 description 3
- ADIMAYPTOBDMTL-UHFFFAOYSA-N oxazepam Chemical compound C12=CC(Cl)=CC=C2NC(=O)C(O)N=C1C1=CC=CC=C1 ADIMAYPTOBDMTL-UHFFFAOYSA-N 0.000 description 3
- 235000011069 sorbitan monooleate Nutrition 0.000 description 3
- 239000001593 sorbitan monooleate Substances 0.000 description 3
- 229940035049 sorbitan monooleate Drugs 0.000 description 3
- 239000004094 surface-active agent Substances 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 229920001328 Polyvinylidene chloride Polymers 0.000 description 2
- 239000002585 base Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 238000011049 filling Methods 0.000 description 2
- 239000003617 indole-3-acetic acid Substances 0.000 description 2
- JTEDVYBZBROSJT-UHFFFAOYSA-N indole-3-butyric acid Chemical compound C1=CC=C2C(CCCC(=O)O)=CNC2=C1 JTEDVYBZBROSJT-UHFFFAOYSA-N 0.000 description 2
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 239000008177 pharmaceutical agent Substances 0.000 description 2
- 230000008635 plant growth Effects 0.000 description 2
- -1 polytetrafluoroethylene Polymers 0.000 description 2
- 239000005033 polyvinylidene chloride Substances 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- DIWRORZWFLOCLC-HNNXBMFYSA-N (3s)-7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one Chemical compound N([C@H](C(NC1=CC=C(Cl)C=C11)=O)O)=C1C1=CC=CC=C1Cl DIWRORZWFLOCLC-HNNXBMFYSA-N 0.000 description 1
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- 241000220479 Acacia Species 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- 229920002307 Dextran Polymers 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 235000010643 Leucaena leucocephala Nutrition 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- SEQDDYPDSLOBDC-UHFFFAOYSA-N Temazepam Chemical compound N=1C(O)C(=O)N(C)C2=CC=C(Cl)C=C2C=1C1=CC=CC=C1 SEQDDYPDSLOBDC-UHFFFAOYSA-N 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229960003515 bendroflumethiazide Drugs 0.000 description 1
- HDWIHXWEUNVBIY-UHFFFAOYSA-N bendroflumethiazidum Chemical compound C1=C(C(F)(F)F)C(S(=O)(=O)N)=CC(S(N2)(=O)=O)=C1NC2CC1=CC=CC=C1 HDWIHXWEUNVBIY-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 239000011247 coating layer Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 239000002826 coolant Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000006184 cosolvent Substances 0.000 description 1
- 229940019862 cyclopenthiazide 0.5 mg Drugs 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 238000009363 floriculture Methods 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- ZZUFCTLCJUWOSV-UHFFFAOYSA-N furosemide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC(C(O)=O)=C1NCC1=CC=CO1 ZZUFCTLCJUWOSV-UHFFFAOYSA-N 0.000 description 1
- 229960003883 furosemide Drugs 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 229960000905 indomethacin Drugs 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 239000002648 laminated material Substances 0.000 description 1
- 229960004391 lorazepam Drugs 0.000 description 1
- 229940033312 lormetazepam 1 mg Drugs 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- 230000005499 meniscus Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 229940127234 oral contraceptive Drugs 0.000 description 1
- 239000003539 oral contraceptive agent Substances 0.000 description 1
- 229940080083 oxazepam 15 mg Drugs 0.000 description 1
- 229940095438 oxazepam 30 mg Drugs 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 229920006316 polyvinylpyrrolidine Polymers 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 238000000527 sonication Methods 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 229960003188 temazepam Drugs 0.000 description 1
- 238000003856 thermoforming Methods 0.000 description 1
- 239000012815 thermoplastic material Substances 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/34—Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Environmental Sciences (AREA)
- Mechanical Engineering (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Dentistry (AREA)
- Toxicology (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Materials For Medical Uses (AREA)
- Glass Compositions (AREA)
- Seasonings (AREA)
- Jellies, Jams, And Syrups (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8136360 | 1981-12-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS238637B2 true CS238637B2 (en) | 1985-12-16 |
Family
ID=10526336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS828515A CS238637B2 (en) | 1981-12-02 | 1982-11-26 | Production method of a rigid shaped article including in advance chosen amount unit of chemical compound |
Country Status (41)
| Country | Link |
|---|---|
| US (1) | US4758598A (pl) |
| EP (1) | EP0081912B1 (pl) |
| JP (1) | JPS58113123A (pl) |
| KR (1) | KR880001206B1 (pl) |
| AR (1) | AR229543A1 (pl) |
| AT (1) | ATE27058T1 (pl) |
| AU (1) | AU554816B2 (pl) |
| BR (1) | BR8206982A (pl) |
| CA (1) | CA1200960A (pl) |
| CS (1) | CS238637B2 (pl) |
| CY (1) | CY1326A (pl) |
| DD (1) | DD206534A1 (pl) |
| DE (1) | DE3276260D1 (pl) |
| DK (1) | DK159797C (pl) |
| DO (1) | DOP1982004083A (pl) |
| DZ (1) | DZ481A1 (pl) |
| EG (1) | EG15502A (pl) |
| ES (1) | ES517853A0 (pl) |
| FI (1) | FI77155C (pl) |
| GB (1) | GB2119246B (pl) |
| GR (1) | GR77773B (pl) |
| HK (1) | HK19586A (pl) |
| HU (1) | HU187802B (pl) |
| IE (1) | IE53696B1 (pl) |
| IL (1) | IL67266A (pl) |
| IN (1) | IN157896B (pl) |
| JO (1) | JO1225B1 (pl) |
| KE (1) | KE3601D (pl) |
| MA (1) | MA19658A1 (pl) |
| MX (1) | MX195411A (pl) |
| MY (1) | MY8600502A (pl) |
| NO (1) | NO159060C (pl) |
| NZ (1) | NZ202482A (pl) |
| PH (1) | PH18441A (pl) |
| PL (1) | PL139503B1 (pl) |
| PT (1) | PT75923B (pl) |
| SA (1) | SA91110229B1 (pl) |
| SU (1) | SU1514239A3 (pl) |
| YU (1) | YU43727B (pl) |
| ZA (1) | ZA828371B (pl) |
| ZW (1) | ZW25282A1 (pl) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4950689A (en) * | 1987-03-31 | 1990-08-21 | Yang Robert K | Pectin delivery system |
| US5206025A (en) * | 1989-05-24 | 1993-04-27 | Rhone-Poulenc Sante | Porous pharmaceutical form and its preparation |
| US4946684A (en) * | 1989-06-20 | 1990-08-07 | American Home Products Corporation | Fast dissolving dosage forms |
| US5215756A (en) * | 1989-12-22 | 1993-06-01 | Gole Dilip J | Preparation of pharmaceutical and other matrix systems by solid-state dissolution |
| WO1993012770A1 (en) * | 1991-12-20 | 1993-07-08 | Pfizer Inc. | Porous shaped delivery devices and method of producing thereof |
| JPH07502736A (ja) * | 1992-01-17 | 1995-03-23 | アルファテック−ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 親水性巨大分子からなる骨格を有する作用物質含有固形物およびその調製法 |
| US5876754A (en) * | 1992-01-17 | 1999-03-02 | Alfatec-Pharma Gmbh | Solid bodies containing active substances and a structure consisting of hydrophilic macromolecules, plus a method of producing such bodies |
| US5298261A (en) * | 1992-04-20 | 1994-03-29 | Oregon Freeze Dry, Inc. | Rapidly distintegrating tablet |
| US5271874A (en) * | 1992-11-04 | 1993-12-21 | Wesley-Jessen Corporation | Method for molding a hydrophilic contact lens |
| WO1995001782A2 (en) * | 1993-07-09 | 1995-01-19 | R.P. Scherer Corporation | Method for making freeze dried drug dosage forms |
| US5738875A (en) * | 1994-10-28 | 1998-04-14 | R.P. Scherer Corporation | Process for preparing solid pharmaceutical dosage forms |
| US5837287A (en) * | 1994-10-28 | 1998-11-17 | R P Scherer Corporation | Process for preparing solid pharmaceutical dosage forms |
| ATE241346T1 (de) * | 1995-03-02 | 2003-06-15 | Scherer Technologies Inc R P | Arzneimittel enthaltend monoaminooxidase-b-hemmer |
| EG23659A (en) | 1995-03-24 | 2007-03-26 | Lilly Co Eli | Process and crystal forms of methyl-thieno-benzodiazepine |
| EP0910345B1 (en) | 1996-06-17 | 2002-02-13 | Janssen Pharmaceutica N.V. | Biconvex rapidly disintegrating dosage forms |
| US7255877B2 (en) * | 1996-08-22 | 2007-08-14 | Jagotec Ag | Fenofibrate microparticles |
| US6465016B2 (en) | 1996-08-22 | 2002-10-15 | Research Triangle Pharmaceuticals | Cyclosporiine particles |
| US7189753B1 (en) | 1997-11-06 | 2007-03-13 | Cady Roger K | Preemptive prophylaxis of migraine |
| US6066092A (en) * | 1997-11-06 | 2000-05-23 | Cady; Roger K. | Preemptive prophylaxis of migraine device and method |
| US6979456B1 (en) | 1998-04-01 | 2005-12-27 | Jagotec Ag | Anticancer compositions |
| DE69914742T2 (de) | 1998-05-29 | 2004-11-25 | Skyepharma Canada Inc., Verdun | Gegen hitzeeinwirkung geschützte mikropartikel und verfahren zur terminalen dampfsterilisation derselben |
| RU2233654C2 (ru) | 1998-11-20 | 2004-08-10 | Ртп Фарма Инк. | Диспергируемые стабилизированные фосфолипидом микрочастицы |
| JP4848572B2 (ja) * | 1999-05-07 | 2011-12-28 | 井関農機株式会社 | 乗用型作業車 |
| CN1174741C (zh) * | 1999-09-21 | 2004-11-10 | Rtp药品公司 | 生物活性物质的表面改性微粒组合物 |
| RU2004107501A (ru) * | 2001-08-14 | 2005-02-20 | Байотай Терапис Корпорейшн (Fi) | Способ лечения алкоголизма или злоупотребления алкоголем |
| JP4042394B2 (ja) * | 2001-12-04 | 2008-02-06 | 味の素株式会社 | ブロック状凍結乾燥食品類の製造法 |
| EP1551373B1 (de) * | 2002-10-16 | 2014-11-12 | MedSkin Solutions Dr. Suwelack AG | Verwendung von formkörpern zur äusseren anwendung |
| US20040234579A1 (en) * | 2003-05-22 | 2004-11-25 | Mark D. Finke, Inc. | Dietary supplements and methods of preparing and administering dietary supplements |
| DE20321887U1 (de) | 2003-11-10 | 2012-01-20 | Allergan, Inc. | Arzneimittel umfassend niedrige Dosierungen von Desmopressin |
| AU2003287591C1 (en) | 2003-11-10 | 2009-12-10 | Serenity Pharmaceuticals Llc | Pharmaceutical compositions including low dosages of desmopressin |
| JP2010254691A (ja) | 2009-04-22 | 2010-11-11 | Dr Suwelack Skin & Health Care Ag | コーティングされた凍結乾燥成型品 |
| CN101919805B (zh) | 2009-04-22 | 2014-01-29 | 苏维拉克博士皮肤治疗方案股份公司 | 包含抗坏血酸磷酸酯镁盐的冻干模塑制品 |
| US20130098950A1 (en) * | 2010-05-31 | 2013-04-25 | Haremilik Gida, Dekorasyon Ve Ekipmanlari Ticaret Sanayi Limited Sirketi | Capsule for Pouring a Powder in a Device |
| RU2015128794A (ru) | 2012-12-20 | 2017-01-25 | КАШИВ ФАРМА, ЭлЭлСи | Композиция перорально распадающейся таблетки, обеспечивающая повышенную биодоступность |
| US10238600B2 (en) | 2017-04-13 | 2019-03-26 | Richard C. Fuisz | Package, system and methods for custody and control of drugs, and method and composition for making an oral soluble film, containing at least one active agent |
| US9901545B1 (en) | 2017-04-13 | 2018-02-27 | Richard C. Fuisz | Method and composition for making an oral soluble film, containing at least one active agent |
| AU2019229784A1 (en) | 2018-03-08 | 2020-08-13 | Catalent U.K. Swindon Zydis Limited | Process to reduce endotoxin in gelatin |
| KR20210024549A (ko) * | 2018-06-29 | 2021-03-05 | 우니베르지타이트 겐트 | 제품 용량 단위의 동결, 건조 및/또는 동결 건조 |
| PL3927322T3 (pl) | 2019-02-22 | 2024-02-05 | Catalent U.K. Swindon Zydis Limited | Minimalizacja napowietrzania zawiesin podczas mieszania typu in-line |
| MX2021009845A (es) | 2019-02-22 | 2021-09-10 | Catalent Uk Swindon Zydis Ltd | Minimizacion de la aglomeracion de material de revestimiento de particula de medicamento durante el almacenaje para estabilizar los tiempos de desintegracion de productos farmaceuticos. |
| CA3129404A1 (en) | 2019-02-22 | 2020-08-27 | Catalent U.K. Swindon Zydis Limited | Preserving functionally-coated api particles produced by solventless mixing processes in aqueous suspension |
| MX2021009679A (es) | 2019-02-22 | 2021-09-10 | Catalent Uk Swindon Zydis Ltd | Minimizacion de aglomeracion, aireacion y conservacion del revestimiento de composiciones farmaceuticas que comprenden ibuprofeno. |
| US20230172844A1 (en) * | 2019-08-12 | 2023-06-08 | Tenshi Kaizen Private Limited | Cannabidiol orally disintegrating tablets |
| US11173114B1 (en) | 2020-07-10 | 2021-11-16 | Nova Thin Film Pharmaceuticals Llc | Method and system for manufacturing and oral soluble films and oral soluble films made by thereby |
| AR123109A1 (es) | 2020-07-31 | 2022-10-26 | Catalent Uk Swindon Zydis Ltd | Composiciones farmacéuticas que comprenden ifa |
| EP4294368A4 (en) | 2021-02-19 | 2024-11-06 | Nova Thin Film Pharmaceuticals LLC | METHOD AND SYSTEM FOR PRODUCING ORAL SOLUBLE FILMS, ORAL SOLUBLE FILMS COMPOSITIONS, ORAL SOLUBLE FILMS PRODUCED THEREWITH AND METHODS OF USE THEREOF |
| US20240251791A1 (en) * | 2021-06-02 | 2024-08-01 | Ibiden Co., Ltd. | Powdery plant activator |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE709590A (pl) * | 1967-01-24 | 1968-05-30 | ||
| GB1548022A (en) * | 1976-10-06 | 1979-07-04 | Wyeth John & Brother Ltd | Pharmaceutial dosage forms |
| IE45770B1 (en) * | 1976-10-06 | 1982-11-17 | Wyeth John & Brother Ltd | Pharmaceutical dosage forms |
| CA1097233A (en) * | 1977-07-20 | 1981-03-10 | George K. E. Gregory | Packages |
-
1982
- 1982-11-08 IE IE2663/82A patent/IE53696B1/en not_active IP Right Cessation
- 1982-11-10 CA CA000415339A patent/CA1200960A/en not_active Expired
- 1982-11-11 GR GR69796A patent/GR77773B/el unknown
- 1982-11-11 CY CY1326A patent/CY1326A/en unknown
- 1982-11-11 GB GB08232189A patent/GB2119246B/en not_active Expired
- 1982-11-12 IN IN1325/CAL/82A patent/IN157896B/en unknown
- 1982-11-12 NZ NZ202482A patent/NZ202482A/en unknown
- 1982-11-15 AR AR291296A patent/AR229543A1/es active
- 1982-11-15 EP EP82306067A patent/EP0081912B1/en not_active Expired
- 1982-11-15 IL IL67266A patent/IL67266A/xx not_active IP Right Cessation
- 1982-11-15 AT AT82306067T patent/ATE27058T1/de not_active IP Right Cessation
- 1982-11-15 DE DE8282306067T patent/DE3276260D1/de not_active Expired
- 1982-11-15 ZA ZA828371A patent/ZA828371B/xx unknown
- 1982-11-16 AU AU90618/82A patent/AU554816B2/en not_active Expired
- 1982-11-19 FI FI823983A patent/FI77155C/fi not_active IP Right Cessation
- 1982-11-22 PH PH28170A patent/PH18441A/en unknown
- 1982-11-24 DZ DZ826716A patent/DZ481A1/fr active
- 1982-11-26 YU YU2655/82A patent/YU43727B/xx unknown
- 1982-11-26 CS CS828515A patent/CS238637B2/cs unknown
- 1982-11-29 ZW ZW252/82A patent/ZW25282A1/xx unknown
- 1982-11-30 DK DK532682A patent/DK159797C/da not_active IP Right Cessation
- 1982-11-30 DD DD82245370A patent/DD206534A1/xx unknown
- 1982-11-30 PT PT75923A patent/PT75923B/pt unknown
- 1982-11-30 DO DO1982004083A patent/DOP1982004083A/es unknown
- 1982-12-01 ES ES517853A patent/ES517853A0/es active Granted
- 1982-12-01 EG EG710/82A patent/EG15502A/xx active
- 1982-12-01 NO NO824023A patent/NO159060C/no not_active IP Right Cessation
- 1982-12-01 SU SU823520359A patent/SU1514239A3/ru active
- 1982-12-01 HU HU823858A patent/HU187802B/hu unknown
- 1982-12-01 JO JO19821225A patent/JO1225B1/en active
- 1982-12-01 BR BR8206982A patent/BR8206982A/pt not_active IP Right Cessation
- 1982-12-01 MA MA19871A patent/MA19658A1/fr unknown
- 1982-12-01 KR KR8205393A patent/KR880001206B1/ko not_active Expired
- 1982-12-01 PL PL1982239301A patent/PL139503B1/pl unknown
- 1982-12-02 MX MX19541182A patent/MX195411A/es unknown
- 1982-12-02 JP JP57212580A patent/JPS58113123A/ja active Granted
-
1986
- 1986-01-28 KE KE3601BD patent/KE3601D/xx unknown
- 1986-03-20 HK HK195/86A patent/HK19586A/xx not_active IP Right Cessation
- 1986-04-08 US US06/850,430 patent/US4758598A/en not_active Expired - Fee Related
- 1986-12-30 MY MY502/86A patent/MY8600502A/xx unknown
-
1991
- 1991-02-11 SA SA91110229A patent/SA91110229B1/ar unknown
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