CS235979B2 - Method of new anti-tumor analogues-daunorubicine and doxorubicine production - Google Patents

Method of new anti-tumor analogues-daunorubicine and doxorubicine production Download PDF

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Publication number
CS235979B2
CS235979B2 CS83374A CS37483A CS235979B2 CS 235979 B2 CS235979 B2 CS 235979B2 CS 83374 A CS83374 A CS 83374A CS 37483 A CS37483 A CS 37483A CS 235979 B2 CS235979 B2 CS 235979B2
Authority
CS
Czechoslovakia
Prior art keywords
tumor
hydrogen
day
methyl
effective
Prior art date
Application number
CS83374A
Other languages
Czech (cs)
English (en)
Inventor
Sergio Penco
Giuliano Franchi
Federico Arcamone
Anna M Casazza
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of CS235979B2 publication Critical patent/CS235979B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CS83374A 1982-01-26 1983-01-19 Method of new anti-tumor analogues-daunorubicine and doxorubicine production CS235979B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8202080 1982-01-26

Publications (1)

Publication Number Publication Date
CS235979B2 true CS235979B2 (en) 1985-05-15

Family

ID=10527864

Family Applications (1)

Application Number Title Priority Date Filing Date
CS83374A CS235979B2 (en) 1982-01-26 1983-01-19 Method of new anti-tumor analogues-daunorubicine and doxorubicine production

Country Status (28)

Country Link
JP (1) JPS58128396A (fi)
KR (1) KR900006214B1 (fi)
AT (1) AT378776B (fi)
AU (1) AU551700B2 (fi)
BE (1) BE895687A (fi)
CA (1) CA1197237A (fi)
CH (1) CH657622A5 (fi)
CS (1) CS235979B2 (fi)
DE (1) DE3301489A1 (fi)
DK (1) DK157322C (fi)
ES (1) ES8403140A1 (fi)
FI (1) FI74977C (fi)
FR (1) FR2520365B1 (fi)
GB (1) GB2116169B (fi)
GR (1) GR77890B (fi)
HU (1) HU192784B (fi)
IE (1) IE53750B1 (fi)
IL (1) IL67709A (fi)
IT (1) IT1210482B (fi)
NL (1) NL8300150A (fi)
NO (1) NO153456C (fi)
NZ (1) NZ203047A (fi)
PH (1) PH19130A (fi)
PT (1) PT76113A (fi)
SE (1) SE461591B (fi)
SU (1) SU1187724A3 (fi)
YU (1) YU43536B (fi)
ZA (1) ZA83450B (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2182926B (en) * 1985-11-19 1989-10-04 Erba Farmitalia Nitro anthracyclines, process for their preparation and use thereof
GB8708927D0 (en) * 1987-04-14 1987-05-20 Erba Farmitalia Chiral synthesis of anthracyclines

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1509875A (en) * 1976-06-14 1978-05-04 Farmaceutici Italia Optically active anthracyclinones and anthracycline glycosides
GB1573037A (en) * 1977-05-05 1980-08-13 Farmaceutici Italia Anthracyclines
ATE4387T1 (de) * 1979-07-04 1983-08-15 Farmitalia Carlo Erba S.P.A. Anthracyclin-glycoside, verfahren zu ihrer herstellung und sie enthaltende therapeutische zusammensetzung.
DE3100968A1 (de) * 1980-01-16 1982-01-14 Farmitalia Carlo Erba S.p.A., 20159 Milano Anthracyclinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
GB8301178D0 (en) 1983-02-16
ATA15683A (de) 1985-02-15
NL8300150A (nl) 1983-08-16
KR840003262A (ko) 1984-08-20
FI74977B (fi) 1987-12-31
IE53750B1 (en) 1989-02-01
FI830155L (fi) 1983-07-27
ZA83450B (en) 1983-10-26
DK157322B (da) 1989-12-11
DE3301489A1 (de) 1983-08-04
DK157322C (da) 1990-05-07
PT76113A (en) 1983-02-01
NO153456B (no) 1985-12-16
FR2520365A1 (fr) 1983-07-29
AU551700B2 (en) 1986-05-08
ES519255A0 (es) 1984-03-01
IE830144L (en) 1983-07-26
ES8403140A1 (es) 1984-03-01
NO830234L (no) 1983-07-27
KR900006214B1 (ko) 1990-08-25
JPS58128396A (ja) 1983-07-30
SU1187724A3 (ru) 1985-10-23
CH657622A5 (it) 1986-09-15
SE8300324L (sv) 1983-07-27
IL67709A (en) 1986-03-31
FI74977C (fi) 1988-04-11
HU192784B (en) 1987-07-28
GB2116169A (en) 1983-09-21
FI830155A0 (fi) 1983-01-17
PH19130A (en) 1986-01-08
SE461591B (sv) 1990-03-05
DK27683D0 (da) 1983-01-25
BE895687A (fr) 1983-05-16
NO153456C (no) 1986-03-26
IL67709A0 (en) 1983-05-15
GR77890B (fi) 1984-09-25
GB2116169B (en) 1985-09-04
IT1210482B (it) 1989-09-14
YU43536B (en) 1989-08-31
NZ203047A (en) 1985-10-11
YU8983A (en) 1986-02-28
AU1052583A (en) 1983-08-04
CA1197237A (en) 1985-11-26
AT378776B (de) 1985-09-25
JPS6328436B2 (fi) 1988-06-08
FR2520365B1 (fr) 1985-07-12
SE8300324D0 (sv) 1983-01-21
DK27683A (da) 1983-07-27
DE3301489C2 (fi) 1988-01-28
IT8319147A0 (it) 1983-01-18

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