CS234018B2 - Method of 3,5-diammino-6-1,2,4-triazine derivatives making - Google Patents

Method of 3,5-diammino-6-1,2,4-triazine derivatives making Download PDF

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Publication number
CS234018B2
CS234018B2 CS803829A CS382980A CS234018B2 CS 234018 B2 CS234018 B2 CS 234018B2 CS 803829 A CS803829 A CS 803829A CS 382980 A CS382980 A CS 382980A CS 234018 B2 CS234018 B2 CS 234018B2
Authority
CS
Czechoslovakia
Prior art keywords
hydrogen
chlorine
bromine
compounds
trifluoromethyl
Prior art date
Application number
CS803829A
Other languages
Czech (cs)
English (en)
Inventor
Martin G Baxter
Albert R Elphick
Alistair A Miller
David A Sawyer
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10505597&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CS234018(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of CS234018B2 publication Critical patent/CS234018B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
CS803829A 1979-06-01 1980-05-30 Method of 3,5-diammino-6-1,2,4-triazine derivatives making CS234018B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7919257 1979-06-01

Publications (1)

Publication Number Publication Date
CS234018B2 true CS234018B2 (en) 1985-03-14

Family

ID=10505597

Family Applications (1)

Application Number Title Priority Date Filing Date
CS803829A CS234018B2 (en) 1979-06-01 1980-05-30 Method of 3,5-diammino-6-1,2,4-triazine derivatives making

Country Status (30)

Country Link
US (2) US4486354A (ru)
EP (2) EP0059987B1 (ru)
JP (2) JPS5625169A (ru)
AR (1) AR227521A1 (ru)
AT (1) AT370097B (ru)
AU (2) AU530999B2 (ru)
BG (1) BG60427B2 (ru)
CA (1) CA1112643A (ru)
CS (1) CS234018B2 (ru)
CZ (1) CZ384891A3 (ru)
DD (1) DD151309A5 (ru)
DK (1) DK153787C (ru)
ES (1) ES8104993A1 (ru)
FI (1) FI67844C (ru)
GE (1) GEP19960470B (ru)
GR (1) GR68380B (ru)
HU (1) HU182086B (ru)
IE (1) IE49823B1 (ru)
IL (1) IL60201A (ru)
IT (1) IT1147087B (ru)
MX (1) MX9202962A (ru)
MY (1) MY8500062A (ru)
NL (1) NL950007I2 (ru)
NZ (1) NZ193890A (ru)
PL (1) PL124029B1 (ru)
SU (1) SU1055331A3 (ru)
UA (1) UA5576A1 (ru)
YU (1) YU145680A (ru)
ZA (1) ZA803250B (ru)
ZW (1) ZW12980A1 (ru)

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TWI808952B (zh) 2016-12-16 2023-07-21 瑞士商愛杜西亞製藥有限公司 包含t型鈣通道阻斷劑之醫藥組合
TWI826531B (zh) 2018-09-21 2023-12-21 南韓商愛思開生物製藥股份有限公司 具有㗁二唑之化合物及包含該化合物之醫藥組合物

Family Cites Families (8)

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GB759014A (en) * 1952-02-26 1956-10-10 Wellcome Found Improvements in triazines and their manufacture
AT190941B (de) * 1954-09-22 1957-07-25 Chemie Linz Ag Verfahren zur Herstellung neuer Guanylhydrazone
US2952677A (en) * 1956-10-01 1960-09-13 Ici Ltd Aminoguanadine compounds
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EP0086502B1 (en) * 1979-08-16 1987-03-25 The Wellcome Foundation Limited Substituted aromatic triazines

Also Published As

Publication number Publication date
ES491998A0 (es) 1981-05-16
EP0021121A1 (en) 1981-01-07
HU182086B (en) 1983-12-28
IL60201A (en) 1984-05-31
AU5890680A (en) 1980-12-04
IT8048848A0 (it) 1980-05-30
IL60201A0 (en) 1980-07-31
UA5576A1 (uk) 1994-12-28
ZW12980A1 (en) 1982-01-06
NL950007I2 (nl) 1997-02-03
ZA803250B (en) 1982-01-27
ES8104993A1 (es) 1981-05-16
EP0059987A1 (en) 1982-09-15
JPS6133163A (ja) 1986-02-17
JPH0144706B2 (ru) 1989-09-29
AU530999B2 (en) 1983-08-04
DK233880A (da) 1980-12-02
AU566870B2 (en) 1987-11-05
IE801126L (en) 1980-12-01
EP0021121B1 (en) 1983-05-11
ATA289680A (de) 1982-07-15
EP0059987B1 (en) 1985-08-14
FI801758A (fi) 1980-12-02
GEP19960470B (en) 1996-08-29
AT370097B (de) 1983-02-25
CZ384891A3 (en) 1993-10-13
SU1055331A3 (ru) 1983-11-15
FI67844C (fi) 1985-06-10
JPH0144179B2 (ru) 1989-09-26
US4486354A (en) 1984-12-04
NZ193890A (en) 1984-07-06
FI67844B (fi) 1985-02-28
AR227521A1 (es) 1982-11-15
NL950007I1 (nl) 1995-06-16
DK153787B (da) 1988-09-05
MY8500062A (en) 1985-12-31
DD151309A5 (de) 1981-10-14
US4602017A (en) 1986-07-22
MX9202962A (es) 1992-07-01
IE49823B1 (en) 1985-12-25
CA1112643A (en) 1981-11-17
YU145680A (en) 1983-02-28
IT1147087B (it) 1986-11-19
DK153787C (da) 1989-01-16
GR68380B (ru) 1981-12-28
PL124029B1 (en) 1982-12-31
PL224633A1 (ru) 1981-02-13
BG60427B2 (bg) 1995-03-31
JPS5625169A (en) 1981-03-10

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