CS230562B2 - Production method of halogen n-/mepkaptoacyl/proline derivatives - Google Patents
Production method of halogen n-/mepkaptoacyl/proline derivatives Download PDFInfo
- Publication number
- CS230562B2 CS230562B2 CS791134A CS113479A CS230562B2 CS 230562 B2 CS230562 B2 CS 230562B2 CS 791134 A CS791134 A CS 791134A CS 113479 A CS113479 A CS 113479A CS 230562 B2 CS230562 B2 CS 230562B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- hydrogen
- ethyl acetate
- acid
- formula
- proline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87903278A | 1978-02-21 | 1978-02-21 | |
| US93914878A | 1978-09-01 | 1978-09-01 | |
| US05/939,147 US4154935A (en) | 1978-02-21 | 1978-09-01 | Halogen substituted mercaptoacylamino acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS230562B2 true CS230562B2 (en) | 1984-08-13 |
Family
ID=27420501
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS791134A CS230562B2 (en) | 1978-02-21 | 1979-02-20 | Production method of halogen n-/mepkaptoacyl/proline derivatives |
Country Status (26)
| Country | Link |
|---|---|
| JP (1) | JPS54125656A (ja) |
| AR (2) | AR229152A1 (ja) |
| CA (1) | CA1124723A (ja) |
| CH (1) | CH639370A5 (ja) |
| CS (1) | CS230562B2 (ja) |
| DD (1) | DD141827A5 (ja) |
| DE (1) | DE2906768A1 (ja) |
| DK (1) | DK73379A (ja) |
| ES (3) | ES477878A1 (ja) |
| FI (1) | FI790593A (ja) |
| FR (1) | FR2417499A1 (ja) |
| GB (1) | GB2014987B (ja) |
| GR (1) | GR82336B (ja) |
| HK (1) | HK41383A (ja) |
| IE (1) | IE47971B1 (ja) |
| IL (1) | IL56662A0 (ja) |
| LU (1) | LU80946A1 (ja) |
| NL (1) | NL7901319A (ja) |
| NO (1) | NO790568L (ja) |
| NZ (1) | NZ189626A (ja) |
| PH (1) | PH15381A (ja) |
| PL (1) | PL118158B1 (ja) |
| PT (1) | PT69254A (ja) |
| RO (1) | RO77228A (ja) |
| SE (1) | SE431643B (ja) |
| SU (1) | SU882409A3 (ja) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1144930A (en) * | 1978-08-11 | 1983-04-19 | Miguel A. Ondetti | Mercaptoacyl derivatives of substituted prolines |
| NL7809120A (nl) * | 1978-09-07 | 1980-03-11 | Oce Andeno B V Grubbenvorsterw | Werkwijze voor de bereiding van proline-derivaten. |
| US4483861A (en) * | 1978-10-31 | 1984-11-20 | Santen Pharmaceutical Co., Ltd. | Antihypertensive sulfur-containing compounds |
| CA1132985A (en) * | 1978-12-22 | 1982-10-05 | John Krapcho | Ketal and thioketal derivatives of mercaptoacyl prolines |
| ZA802420B (en) * | 1979-05-18 | 1981-04-29 | Squibb & Sons Inc | Aminoacyl derivatives of mercaptoacyl amino acids |
| US4288368A (en) * | 1979-07-30 | 1981-09-08 | E. R. Squibb & Sons, Inc. | Dithioacylproline derivatives |
| AU542211B2 (en) * | 1980-03-07 | 1985-02-14 | Gruppo Lepetit S.P.A. | Mercaptocycloalkyl carbonyl prolines |
| JP2005213165A (ja) * | 2004-01-28 | 2005-08-11 | Mitsui Chemicals Inc | フルオロプロリン類の製造方法 |
| JP2011121872A (ja) * | 2009-12-08 | 2011-06-23 | Central Glass Co Ltd | 光学活性Ｎ−ｔｅｒｔ−ブトキシカルボニル−トランス−４−フルオロプロリンの精製方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU509899B2 (en) * | 1976-02-13 | 1980-05-29 | E.R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
-
1970
- 1970-02-15 PH PH22197A patent/PH15381A/en unknown
-
1979
- 1979-02-08 CA CA321,233A patent/CA1124723A/en not_active Expired
- 1979-02-12 NZ NZ189626A patent/NZ189626A/xx unknown
- 1979-02-13 GR GR58343A patent/GR82336B/el unknown
- 1979-02-14 IL IL56662A patent/IL56662A0/xx not_active IP Right Cessation
- 1979-02-15 IE IE297/79A patent/IE47971B1/en not_active IP Right Cessation
- 1979-02-19 GB GB7905788A patent/GB2014987B/en not_active Expired
- 1979-02-20 NO NO790568A patent/NO790568L/no unknown
- 1979-02-20 LU LU80946A patent/LU80946A1/xx unknown
- 1979-02-20 SE SE7901510A patent/SE431643B/sv not_active IP Right Cessation
- 1979-02-20 CS CS791134A patent/CS230562B2/cs unknown
- 1979-02-20 AR AR275559A patent/AR229152A1/es active
- 1979-02-20 PT PT69254A patent/PT69254A/pt unknown
- 1979-02-20 DK DK73379A patent/DK73379A/da unknown
- 1979-02-20 ES ES477878A patent/ES477878A1/es not_active Expired
- 1979-02-20 NL NL7901319A patent/NL7901319A/xx not_active Application Discontinuation
- 1979-02-21 PL PL1979213593A patent/PL118158B1/pl unknown
- 1979-02-21 FI FI790593A patent/FI790593A/fi unknown
- 1979-02-21 RO RO7996682A patent/RO77228A/ro unknown
- 1979-02-21 DE DE19792906768 patent/DE2906768A1/de not_active Ceased
- 1979-02-21 FR FR7904455A patent/FR2417499A1/fr active Granted
- 1979-02-21 JP JP2019979A patent/JPS54125656A/ja active Granted
- 1979-02-21 DD DD79211155A patent/DD141827A5/de unknown
- 1979-02-21 CH CH168679A patent/CH639370A5/fr not_active IP Right Cessation
- 1979-04-23 ES ES479832A patent/ES479832A1/es not_active Expired
- 1979-04-23 ES ES479833A patent/ES479833A1/es not_active Expired
-
1980
- 1980-02-04 SU SU802878653A patent/SU882409A3/ru active
- 1980-06-23 AR AR281499A patent/AR228036A1/es active
-
1983
- 1983-10-13 HK HK413/83A patent/HK41383A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR229152A1 (es) | 1983-06-30 |
| PL213593A1 (ja) | 1980-02-25 |
| PT69254A (en) | 1979-03-01 |
| DK73379A (da) | 1979-08-22 |
| AR228036A1 (es) | 1983-01-14 |
| NL7901319A (nl) | 1979-08-23 |
| NO790568L (no) | 1979-08-22 |
| IL56662A0 (en) | 1979-05-31 |
| IE790297L (en) | 1979-08-21 |
| PL118158B1 (en) | 1981-09-30 |
| FR2417499A1 (fr) | 1979-09-14 |
| SU882409A3 (ru) | 1981-11-15 |
| JPS54125656A (en) | 1979-09-29 |
| FI790593A (fi) | 1979-08-22 |
| JPH0134986B2 (ja) | 1989-07-21 |
| NZ189626A (en) | 1982-03-09 |
| ES479833A1 (es) | 1979-11-16 |
| ES477878A1 (es) | 1980-03-01 |
| HK41383A (en) | 1983-10-21 |
| IE47971B1 (en) | 1984-08-08 |
| CH639370A5 (fr) | 1983-11-15 |
| DE2906768A1 (de) | 1979-08-23 |
| GB2014987A (en) | 1979-09-05 |
| LU80946A1 (fr) | 1979-06-18 |
| ES479832A1 (es) | 1979-11-16 |
| SE431643B (sv) | 1984-02-20 |
| SE7901510L (sv) | 1979-08-22 |
| PH15381A (en) | 1982-12-17 |
| CA1124723A (en) | 1982-06-01 |
| DD141827A5 (de) | 1980-05-21 |
| RO77228A (ro) | 1981-08-17 |
| GR82336B (ja) | 1984-12-13 |
| GB2014987B (en) | 1982-11-03 |
| FR2417499B1 (ja) | 1982-06-04 |
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