FR2417499B1 - - Google Patents

Info

Publication number
FR2417499B1
FR2417499B1 FR7904455A FR7904455A FR2417499B1 FR 2417499 B1 FR2417499 B1 FR 2417499B1 FR 7904455 A FR7904455 A FR 7904455A FR 7904455 A FR7904455 A FR 7904455A FR 2417499 B1 FR2417499 B1 FR 2417499B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7904455A
Other languages
French (fr)
Other versions
FR2417499A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/939,147 external-priority patent/US4154935A/en
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2417499A1 publication Critical patent/FR2417499A1/fr
Application granted granted Critical
Publication of FR2417499B1 publication Critical patent/FR2417499B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
FR7904455A 1978-02-21 1979-02-21 Mercaptoacylamino-acides halogenes et leur utilisation therapeutique Granted FR2417499A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87903278A 1978-02-21 1978-02-21
US93914878A 1978-09-01 1978-09-01
US05/939,147 US4154935A (en) 1978-02-21 1978-09-01 Halogen substituted mercaptoacylamino acids

Publications (2)

Publication Number Publication Date
FR2417499A1 FR2417499A1 (fr) 1979-09-14
FR2417499B1 true FR2417499B1 (ja) 1982-06-04

Family

ID=27420501

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7904455A Granted FR2417499A1 (fr) 1978-02-21 1979-02-21 Mercaptoacylamino-acides halogenes et leur utilisation therapeutique

Country Status (26)

Country Link
JP (1) JPS54125656A (ja)
AR (2) AR229152A1 (ja)
CA (1) CA1124723A (ja)
CH (1) CH639370A5 (ja)
CS (1) CS230562B2 (ja)
DD (1) DD141827A5 (ja)
DE (1) DE2906768A1 (ja)
DK (1) DK73379A (ja)
ES (3) ES477878A1 (ja)
FI (1) FI790593A (ja)
FR (1) FR2417499A1 (ja)
GB (1) GB2014987B (ja)
GR (1) GR82336B (ja)
HK (1) HK41383A (ja)
IE (1) IE47971B1 (ja)
IL (1) IL56662A0 (ja)
LU (1) LU80946A1 (ja)
NL (1) NL7901319A (ja)
NO (1) NO790568L (ja)
NZ (1) NZ189626A (ja)
PH (1) PH15381A (ja)
PL (1) PL118158B1 (ja)
PT (1) PT69254A (ja)
RO (1) RO77228A (ja)
SE (1) SE431643B (ja)
SU (1) SU882409A3 (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1144930A (en) * 1978-08-11 1983-04-19 Miguel A. Ondetti Mercaptoacyl derivatives of substituted prolines
NL7809120A (nl) * 1978-09-07 1980-03-11 Oce Andeno B V Grubbenvorsterw Werkwijze voor de bereiding van proline-derivaten.
US4483861A (en) * 1978-10-31 1984-11-20 Santen Pharmaceutical Co., Ltd. Antihypertensive sulfur-containing compounds
CA1132985A (en) * 1978-12-22 1982-10-05 John Krapcho Ketal and thioketal derivatives of mercaptoacyl prolines
ZA802420B (en) * 1979-05-18 1981-04-29 Squibb & Sons Inc Aminoacyl derivatives of mercaptoacyl amino acids
US4288368A (en) * 1979-07-30 1981-09-08 E. R. Squibb & Sons, Inc. Dithioacylproline derivatives
AU542211B2 (en) * 1980-03-07 1985-02-14 Gruppo Lepetit S.P.A. Mercaptocycloalkyl carbonyl prolines
JP2005213165A (ja) * 2004-01-28 2005-08-11 Mitsui Chemicals Inc フルオロプロリン類の製造方法
JP2011121872A (ja) * 2009-12-08 2011-06-23 Central Glass Co Ltd 光学活性Ｎ−ｔｅｒｔ−ブトキシカルボニル−トランス−４−フルオロプロリンの精製方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds

Also Published As

Publication number Publication date
AR229152A1 (es) 1983-06-30
PL213593A1 (ja) 1980-02-25
CS230562B2 (en) 1984-08-13
PT69254A (en) 1979-03-01
DK73379A (da) 1979-08-22
AR228036A1 (es) 1983-01-14
NL7901319A (nl) 1979-08-23
NO790568L (no) 1979-08-22
IL56662A0 (en) 1979-05-31
IE790297L (en) 1979-08-21
PL118158B1 (en) 1981-09-30
FR2417499A1 (fr) 1979-09-14
SU882409A3 (ru) 1981-11-15
JPS54125656A (en) 1979-09-29
FI790593A (fi) 1979-08-22
JPH0134986B2 (ja) 1989-07-21
NZ189626A (en) 1982-03-09
ES479833A1 (es) 1979-11-16
ES477878A1 (es) 1980-03-01
HK41383A (en) 1983-10-21
IE47971B1 (en) 1984-08-08
CH639370A5 (fr) 1983-11-15
DE2906768A1 (de) 1979-08-23
GB2014987A (en) 1979-09-05
LU80946A1 (fr) 1979-06-18
ES479832A1 (es) 1979-11-16
SE431643B (sv) 1984-02-20
SE7901510L (sv) 1979-08-22
PH15381A (en) 1982-12-17
CA1124723A (en) 1982-06-01
DD141827A5 (de) 1980-05-21
RO77228A (ro) 1981-08-17
GR82336B (ja) 1984-12-13
GB2014987B (en) 1982-11-03

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Legal Events

Date Code Title Description
ST Notification of lapse