LU80946A1 - Mercaptoacylamino-acides substitues par des halogenes - Google Patents

Mercaptoacylamino-acides substitues par des halogenes

Info

Publication number
LU80946A1
LU80946A1 LU80946A LU80946A LU80946A1 LU 80946 A1 LU80946 A1 LU 80946A1 LU 80946 A LU80946 A LU 80946A LU 80946 A LU80946 A LU 80946A LU 80946 A1 LU80946 A1 LU 80946A1
Authority
LU
Luxembourg
Prior art keywords
halogens
acids substituted
mercaptoacylamino acids
mercaptoacylamino
substituted
Prior art date
Application number
LU80946A
Other languages
English (en)
French (fr)
Inventor
A Ondetti Miguel
W Sprague Peter
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/939,147 external-priority patent/US4154935A/en
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of LU80946A1 publication Critical patent/LU80946A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
LU80946A 1978-02-21 1979-02-20 Mercaptoacylamino-acides substitues par des halogenes LU80946A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87903278A 1978-02-21 1978-02-21
US93914878A 1978-09-01 1978-09-01
US05/939,147 US4154935A (en) 1978-02-21 1978-09-01 Halogen substituted mercaptoacylamino acids

Publications (1)

Publication Number Publication Date
LU80946A1 true LU80946A1 (fr) 1979-06-18

Family

ID=27420501

Family Applications (1)

Application Number Title Priority Date Filing Date
LU80946A LU80946A1 (fr) 1978-02-21 1979-02-20 Mercaptoacylamino-acides substitues par des halogenes

Country Status (26)

Country Link
JP (1) JPS54125656A (ja)
AR (2) AR229152A1 (ja)
CA (1) CA1124723A (ja)
CH (1) CH639370A5 (ja)
CS (1) CS230562B2 (ja)
DD (1) DD141827A5 (ja)
DE (1) DE2906768A1 (ja)
DK (1) DK73379A (ja)
ES (3) ES477878A1 (ja)
FI (1) FI790593A (ja)
FR (1) FR2417499A1 (ja)
GB (1) GB2014987B (ja)
GR (1) GR82336B (ja)
HK (1) HK41383A (ja)
IE (1) IE47971B1 (ja)
IL (1) IL56662A0 (ja)
LU (1) LU80946A1 (ja)
NL (1) NL7901319A (ja)
NO (1) NO790568L (ja)
NZ (1) NZ189626A (ja)
PH (1) PH15381A (ja)
PL (1) PL118158B1 (ja)
PT (1) PT69254A (ja)
RO (1) RO77228A (ja)
SE (1) SE431643B (ja)
SU (1) SU882409A3 (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2440365A1 (fr) * 1978-10-31 1980-05-30 Santen Pharmaceutical Co Ltd Nouveaux derives d'acides mercapto-azolidine-carboxyliques utiles comme hypertenseurs
FR2444669A1 (fr) * 1978-12-22 1980-07-18 Squibb & Sons Inc Acetals et thioacetals de mercap
FR2462428A1 (fr) * 1979-07-30 1981-02-13 Squibb & Sons Inc Derives d'acide dithioacyldihydropyrazole carboxylique, derives de dithioacylproline, et composes apparentes, a action antihypertensive
FR2477539A1 (fr) * 1980-03-07 1981-09-11 Lepetit Spa Derives de 1-((2-mercaptocycloalkyl)-carbonyl)-l-prolines, procede pour leur preparatitn, produits intermediaires de leur synthese et leur utilisation en tant qu'agents anti-hypertenseurs

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1144930A (en) * 1978-08-11 1983-04-19 Miguel A. Ondetti Mercaptoacyl derivatives of substituted prolines
NL7809120A (nl) * 1978-09-07 1980-03-11 Oce Andeno B V Grubbenvorsterw Werkwijze voor de bereiding van proline-derivaten.
ZA802420B (en) * 1979-05-18 1981-04-29 Squibb & Sons Inc Aminoacyl derivatives of mercaptoacyl amino acids
JP2005213165A (ja) * 2004-01-28 2005-08-11 Mitsui Chemicals Inc フルオロプロリン類の製造方法
JP2011121872A (ja) * 2009-12-08 2011-06-23 Central Glass Co Ltd 光学活性Ｎ−ｔｅｒｔ−ブトキシカルボニル−トランス−４−フルオロプロリンの精製方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2440365A1 (fr) * 1978-10-31 1980-05-30 Santen Pharmaceutical Co Ltd Nouveaux derives d'acides mercapto-azolidine-carboxyliques utiles comme hypertenseurs
FR2444669A1 (fr) * 1978-12-22 1980-07-18 Squibb & Sons Inc Acetals et thioacetals de mercap
FR2462428A1 (fr) * 1979-07-30 1981-02-13 Squibb & Sons Inc Derives d'acide dithioacyldihydropyrazole carboxylique, derives de dithioacylproline, et composes apparentes, a action antihypertensive
FR2477539A1 (fr) * 1980-03-07 1981-09-11 Lepetit Spa Derives de 1-((2-mercaptocycloalkyl)-carbonyl)-l-prolines, procede pour leur preparatitn, produits intermediaires de leur synthese et leur utilisation en tant qu'agents anti-hypertenseurs

Also Published As

Publication number Publication date
CS230562B2 (en) 1984-08-13
SE431643B (sv) 1984-02-20
NL7901319A (nl) 1979-08-23
PL213593A1 (ja) 1980-02-25
IL56662A0 (en) 1979-05-31
CA1124723A (en) 1982-06-01
PT69254A (en) 1979-03-01
HK41383A (en) 1983-10-21
FR2417499B1 (ja) 1982-06-04
ES479833A1 (es) 1979-11-16
RO77228A (ro) 1981-08-17
NO790568L (no) 1979-08-22
FI790593A (fi) 1979-08-22
DE2906768A1 (de) 1979-08-23
GR82336B (ja) 1984-12-13
SE7901510L (sv) 1979-08-22
ES479832A1 (es) 1979-11-16
FR2417499A1 (fr) 1979-09-14
DD141827A5 (de) 1980-05-21
JPS54125656A (en) 1979-09-29
AR229152A1 (es) 1983-06-30
GB2014987B (en) 1982-11-03
IE790297L (en) 1979-08-21
DK73379A (da) 1979-08-22
JPH0134986B2 (ja) 1989-07-21
ES477878A1 (es) 1980-03-01
NZ189626A (en) 1982-03-09
CH639370A5 (fr) 1983-11-15
PH15381A (en) 1982-12-17
IE47971B1 (en) 1984-08-08
AR228036A1 (es) 1983-01-14
SU882409A3 (ru) 1981-11-15
PL118158B1 (en) 1981-09-30
GB2014987A (en) 1979-09-05

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