LU80946A1 - MERCAPTOACYLAMINO ACIDS SUBSTITUTED BY HALOGENS - Google Patents

MERCAPTOACYLAMINO ACIDS SUBSTITUTED BY HALOGENS

Info

Publication number
LU80946A1
LU80946A1 LU80946A LU80946A LU80946A1 LU 80946 A1 LU80946 A1 LU 80946A1 LU 80946 A LU80946 A LU 80946A LU 80946 A LU80946 A LU 80946A LU 80946 A1 LU80946 A1 LU 80946A1
Authority
LU
Luxembourg
Prior art keywords
halogens
acids substituted
mercaptoacylamino acids
mercaptoacylamino
substituted
Prior art date
Application number
LU80946A
Other languages
French (fr)
Inventor
A Ondetti Miguel
W Sprague Peter
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/939,147 external-priority patent/US4154935A/en
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of LU80946A1 publication Critical patent/LU80946A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
LU80946A 1978-02-21 1979-02-20 MERCAPTOACYLAMINO ACIDS SUBSTITUTED BY HALOGENS LU80946A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87903278A 1978-02-21 1978-02-21
US93914878A 1978-09-01 1978-09-01
US05/939,147 US4154935A (en) 1978-02-21 1978-09-01 Halogen substituted mercaptoacylamino acids

Publications (1)

Publication Number Publication Date
LU80946A1 true LU80946A1 (en) 1979-06-18

Family

ID=27420501

Family Applications (1)

Application Number Title Priority Date Filing Date
LU80946A LU80946A1 (en) 1978-02-21 1979-02-20 MERCAPTOACYLAMINO ACIDS SUBSTITUTED BY HALOGENS

Country Status (26)

Country Link
JP (1) JPS54125656A (en)
AR (2) AR229152A1 (en)
CA (1) CA1124723A (en)
CH (1) CH639370A5 (en)
CS (1) CS230562B2 (en)
DD (1) DD141827A5 (en)
DE (1) DE2906768A1 (en)
DK (1) DK73379A (en)
ES (3) ES477878A1 (en)
FI (1) FI790593A (en)
FR (1) FR2417499A1 (en)
GB (1) GB2014987B (en)
GR (1) GR82336B (en)
HK (1) HK41383A (en)
IE (1) IE47971B1 (en)
IL (1) IL56662A0 (en)
LU (1) LU80946A1 (en)
NL (1) NL7901319A (en)
NO (1) NO790568L (en)
NZ (1) NZ189626A (en)
PH (1) PH15381A (en)
PL (1) PL118158B1 (en)
PT (1) PT69254A (en)
RO (1) RO77228A (en)
SE (1) SE431643B (en)
SU (1) SU882409A3 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2440365A1 (en) * 1978-10-31 1980-05-30 Santen Pharmaceutical Co Ltd NOVEL MERCAPTO-AZOLIDINE-CARBOXYLIC ACID DERIVATIVES USEFUL AS HYPERTENSORS
FR2444669A1 (en) * 1978-12-22 1980-07-18 Squibb & Sons Inc MERCAP ACETALS AND THIOACETALS
FR2462428A1 (en) * 1979-07-30 1981-02-13 Squibb & Sons Inc DITHIOACYLDIHYDROPYRAZOLE CARBOXYLIC ACID DERIVATIVES, DITHIOACYLPROLINE DERIVATIVES, AND RELATED COMPOUNDS WITH ANTIHYPERTENSIVE ACTION
FR2477539A1 (en) * 1980-03-07 1981-09-11 Lepetit Spa 1 - ((2-MERCAPTOCYCLOALKYL) -CARBONYL) -L-PROLINES DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, INTERMEDIATE PRODUCTS OF THEIR SYNTHESIS AND THEIR USE AS ANTI-HYPERTENISING AGENTS

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1144930A (en) * 1978-08-11 1983-04-19 Miguel A. Ondetti Mercaptoacyl derivatives of substituted prolines
NL7809120A (en) * 1978-09-07 1980-03-11 Oce Andeno B V Grubbenvorsterw PROCESS FOR THE PREPARATION OF PROLINE DERIVATIVES.
ZA802420B (en) * 1979-05-18 1981-04-29 Squibb & Sons Inc Aminoacyl derivatives of mercaptoacyl amino acids
JP2005213165A (en) * 2004-01-28 2005-08-11 Mitsui Chemicals Inc Method for producing fluoroproline compounds
JP2011121872A (en) * 2009-12-08 2011-06-23 Central Glass Co Ltd Method for purifying optically active n-tert-butoxycarbonyl-trans-4-fluoroproline

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2440365A1 (en) * 1978-10-31 1980-05-30 Santen Pharmaceutical Co Ltd NOVEL MERCAPTO-AZOLIDINE-CARBOXYLIC ACID DERIVATIVES USEFUL AS HYPERTENSORS
FR2444669A1 (en) * 1978-12-22 1980-07-18 Squibb & Sons Inc MERCAP ACETALS AND THIOACETALS
FR2462428A1 (en) * 1979-07-30 1981-02-13 Squibb & Sons Inc DITHIOACYLDIHYDROPYRAZOLE CARBOXYLIC ACID DERIVATIVES, DITHIOACYLPROLINE DERIVATIVES, AND RELATED COMPOUNDS WITH ANTIHYPERTENSIVE ACTION
FR2477539A1 (en) * 1980-03-07 1981-09-11 Lepetit Spa 1 - ((2-MERCAPTOCYCLOALKYL) -CARBONYL) -L-PROLINES DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, INTERMEDIATE PRODUCTS OF THEIR SYNTHESIS AND THEIR USE AS ANTI-HYPERTENISING AGENTS

Also Published As

Publication number Publication date
AR229152A1 (en) 1983-06-30
JPS54125656A (en) 1979-09-29
ES479833A1 (en) 1979-11-16
GB2014987A (en) 1979-09-05
PL118158B1 (en) 1981-09-30
NZ189626A (en) 1982-03-09
ES477878A1 (en) 1980-03-01
FR2417499B1 (en) 1982-06-04
CS230562B2 (en) 1984-08-13
PL213593A1 (en) 1980-02-25
GR82336B (en) 1984-12-13
IL56662A0 (en) 1979-05-31
DD141827A5 (en) 1980-05-21
HK41383A (en) 1983-10-21
IE47971B1 (en) 1984-08-08
NO790568L (en) 1979-08-22
SE7901510L (en) 1979-08-22
CA1124723A (en) 1982-06-01
SU882409A3 (en) 1981-11-15
RO77228A (en) 1981-08-17
PT69254A (en) 1979-03-01
ES479832A1 (en) 1979-11-16
DE2906768A1 (en) 1979-08-23
SE431643B (en) 1984-02-20
IE790297L (en) 1979-08-21
GB2014987B (en) 1982-11-03
JPH0134986B2 (en) 1989-07-21
FI790593A (en) 1979-08-22
CH639370A5 (en) 1983-11-15
NL7901319A (en) 1979-08-23
AR228036A1 (en) 1983-01-14
FR2417499A1 (en) 1979-09-14
DK73379A (en) 1979-08-22
PH15381A (en) 1982-12-17

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