CS226013B2 - Method of preparing di-ammonium salt of 7beta-(d-(carboxy(4-hydroxyphenyl)-acetyle-amino)-7alpha-methoxy-3-(l(1-methyl-1h-tetrazol-5-yl)-thio)methyl)-8-oxo-5-oxa-1-azabicyclo(4,2,0)oct-2-ene-2-carbaoxylic acid - Google Patents

Method of preparing di-ammonium salt of 7beta-(d-(carboxy(4-hydroxyphenyl)-acetyle-amino)-7alpha-methoxy-3-(l(1-methyl-1h-tetrazol-5-yl)-thio)methyl)-8-oxo-5-oxa-1-azabicyclo(4,2,0)oct-2-ene-2-carbaoxylic acid Download PDF

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Publication number
CS226013B2
CS226013B2 CS803045A CS304580A CS226013B2 CS 226013 B2 CS226013 B2 CS 226013B2 CS 803045 A CS803045 A CS 803045A CS 304580 A CS304580 A CS 304580A CS 226013 B2 CS226013 B2 CS 226013B2
Authority
CS
Czechoslovakia
Prior art keywords
salt
solution
methyl
epimer
acid
Prior art date
Application number
CS803045A
Other languages
Czech (cs)
English (en)
Inventor
Shang Y Kuo
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CS226013B2 publication Critical patent/CS226013B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS803045A 1979-05-01 1980-04-30 Method of preparing di-ammonium salt of 7beta-(d-(carboxy(4-hydroxyphenyl)-acetyle-amino)-7alpha-methoxy-3-(l(1-methyl-1h-tetrazol-5-yl)-thio)methyl)-8-oxo-5-oxa-1-azabicyclo(4,2,0)oct-2-ene-2-carbaoxylic acid CS226013B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/035,037 US4252953A (en) 1979-05-01 1979-05-01 Antibiotic crystalline epimer

Publications (1)

Publication Number Publication Date
CS226013B2 true CS226013B2 (en) 1984-03-19

Family

ID=21880235

Family Applications (1)

Application Number Title Priority Date Filing Date
CS803045A CS226013B2 (en) 1979-05-01 1980-04-30 Method of preparing di-ammonium salt of 7beta-(d-(carboxy(4-hydroxyphenyl)-acetyle-amino)-7alpha-methoxy-3-(l(1-methyl-1h-tetrazol-5-yl)-thio)methyl)-8-oxo-5-oxa-1-azabicyclo(4,2,0)oct-2-ene-2-carbaoxylic acid

Country Status (34)

Country Link
US (1) US4252953A (es)
EP (1) EP0018811B1 (es)
JP (1) JPS55153788A (es)
KR (1) KR840000078B1 (es)
AR (1) AR230450A1 (es)
AT (1) AT370108B (es)
AU (1) AU538283B2 (es)
BE (1) BE882980A (es)
BG (1) BG34905A3 (es)
CA (1) CA1138867A (es)
CH (1) CH646434A5 (es)
CS (1) CS226013B2 (es)
DD (1) DD150352A5 (es)
DE (1) DE3061751D1 (es)
DK (1) DK177980A (es)
EG (1) EG14719A (es)
ES (1) ES8105316A1 (es)
FI (1) FI801345A (es)
FR (1) FR2455605A1 (es)
GB (1) GB2047707B (es)
GR (1) GR68202B (es)
HU (1) HU184750B (es)
IE (1) IE49775B1 (es)
IL (1) IL59912A (es)
IT (1) IT1141935B (es)
LU (1) LU82411A1 (es)
MY (1) MY8500601A (es)
NZ (1) NZ193528A (es)
PH (1) PH15596A (es)
PL (1) PL125579B1 (es)
PT (1) PT71140A (es)
RO (1) RO79684A (es)
SU (1) SU860705A3 (es)
ZA (1) ZA802475B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS597193A (ja) * 1982-07-02 1984-01-14 Shionogi & Co Ltd マロニルメチル基の異性化方法
EP1673272B1 (de) * 2003-10-08 2010-06-30 Behr GmbH & Co. KG Verfahren und vorrichtung zur herstellung eines bauteils, insbesondere eines hybridbaudteils für einen quertr ger eines fahrzeugs sowie bauteil und verwendung eines bauteils
DE502004011050D1 (de) * 2003-10-08 2010-05-27 Behr Gmbh & Co Kg Bauteil, insbesondere hybridträger für ein fahrzeug, und verwendung eines derartigen bauteils

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CY1158A (en) * 1976-03-25 1983-01-28 Shionogi & Co Arylmalonamido-1-oxadethiacephalosporins
CA1085392A (en) * 1976-03-25 1980-09-09 Masayuki Narisada Arylmalonamido-1-oxadethiacephalosporins
US4148997A (en) * 1977-11-07 1979-04-10 Yeda Research And Development Co., Ltd. 7-[Sulfomethyl)phenyl]acetamidocephalosporin derivatives
US4124762A (en) * 1977-11-07 1978-11-07 Yeda Research And Development Co., Ltd. 7-[(Pyridylthiomethyl)phenyl]acetamido-cephalosporin derivatives
US4125715A (en) * 1977-11-25 1978-11-14 Yeda Research And Development Co. Ltd. 7-[(Substituted-isothioureamethyl)phenyl]-acetamidocephalosporin derivatives

Also Published As

Publication number Publication date
NZ193528A (en) 1982-03-23
IE800882L (en) 1980-11-01
AU538283B2 (en) 1984-08-09
BG34905A3 (en) 1983-12-15
ES491085A0 (es) 1981-05-16
DD150352A5 (de) 1981-08-26
ES8105316A1 (es) 1981-05-16
KR830002779A (ko) 1983-05-30
KR840000078B1 (ko) 1984-02-08
JPS55153788A (en) 1980-11-29
HU184750B (en) 1984-10-29
PT71140A (en) 1980-05-01
GR68202B (es) 1981-11-10
GB2047707A (en) 1980-12-03
FR2455605B1 (es) 1983-05-27
PL223753A1 (es) 1981-02-13
DE3061751D1 (en) 1983-03-03
IT8021697A0 (it) 1980-04-29
PL125579B1 (en) 1983-05-31
CA1138867A (en) 1983-01-04
BE882980A (fr) 1980-10-27
EG14719A (en) 1985-06-30
SU860705A3 (ru) 1981-08-30
PH15596A (en) 1983-02-28
JPH0118077B2 (es) 1989-04-03
AT370108B (de) 1983-03-10
GB2047707B (en) 1983-05-18
EP0018811B1 (en) 1983-01-26
MY8500601A (en) 1985-12-31
DK177980A (da) 1980-11-02
AU5791480A (en) 1980-11-06
EP0018811A1 (en) 1980-11-12
ATA220980A (de) 1982-07-15
IT1141935B (it) 1986-10-08
IE49775B1 (en) 1985-12-11
US4252953A (en) 1981-02-24
FI801345A (fi) 1980-11-02
ZA802475B (en) 1981-12-30
IL59912A (en) 1984-02-29
FR2455605A1 (fr) 1980-11-28
RO79684A (ro) 1982-08-17
LU82411A1 (fr) 1980-07-31
AR230450A1 (es) 1984-04-30
CH646434A5 (fr) 1984-11-30

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