CS221269B2 - Method of preparation of new 1,5-disubstituted 2-pyrrolidone compounds - Google Patents

Method of preparation of new 1,5-disubstituted 2-pyrrolidone compounds Download PDF

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Publication number
CS221269B2
CS221269B2 CS775202A CS520277A CS221269B2 CS 221269 B2 CS221269 B2 CS 221269B2 CS 775202 A CS775202 A CS 775202A CS 520277 A CS520277 A CS 520277A CS 221269 B2 CS221269 B2 CS 221269B2
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CS
Czechoslovakia
Prior art keywords
pyrrolidone
ppm
compound
formula
solution
Prior art date
Application number
CS775202A
Other languages
Czech (cs)
English (en)
Inventor
Albin J Nelson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CS221269B2 publication Critical patent/CS221269B2/cs

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CS775202A 1976-08-06 1977-08-05 Method of preparation of new 1,5-disubstituted 2-pyrrolidone compounds CS221269B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71236276A 1976-08-06 1976-08-06

Publications (1)

Publication Number Publication Date
CS221269B2 true CS221269B2 (en) 1983-04-29

Family

ID=24861795

Family Applications (1)

Application Number Title Priority Date Filing Date
CS775202A CS221269B2 (en) 1976-08-06 1977-08-05 Method of preparation of new 1,5-disubstituted 2-pyrrolidone compounds

Country Status (31)

Country Link
JP (2) JPS5321159A (de)
AR (1) AR217080A1 (de)
AT (1) AT362887B (de)
AU (1) AU508007B2 (de)
BE (1) BE857506A (de)
BG (1) BG31073A3 (de)
CA (1) CA1077948A (de)
CH (1) CH624934A5 (de)
CS (1) CS221269B2 (de)
DD (2) DD143768A5 (de)
DE (1) DE2735904A1 (de)
DK (1) DK352077A (de)
ES (2) ES461388A1 (de)
FI (1) FI70009C (de)
FR (1) FR2369260A1 (de)
GB (2) GB1556569A (de)
GR (1) GR68688B (de)
HU (1) HU180273B (de)
IE (1) IE45505B1 (de)
IL (1) IL52615A (de)
LU (1) LU77936A1 (de)
NL (1) NL7708637A (de)
NO (1) NO772752L (de)
NZ (1) NZ184806A (de)
PH (1) PH17398A (de)
PL (2) PL200124A1 (de)
PT (1) PT66891B (de)
SE (1) SE423813B (de)
SU (3) SU703016A3 (de)
YU (1) YU192577A (de)
ZA (1) ZA774704B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5695569A (en) * 1979-12-27 1981-08-03 Canon Inc Forming method for bar lens sphere face
US4321201A (en) * 1980-09-22 1982-03-23 E. I. Du Pont De Nemours And Company Optically active tert-alkyl 7-(2-oxo-5-carbonyloxypyrrolidinyl) heptanoates
JPS59137224A (ja) * 1983-01-25 1984-08-07 Mitsubishi Electric Corp 電気鉄道用き電電圧補償装置
ATE327751T1 (de) * 2000-01-31 2006-06-15 Pfizer Prod Inc Verwendung von aktivatoren des prostaglandinrezeptores 4 zur behandlung von akuter oder chronischer niereninsuffizienz
WO2002024647A1 (fr) * 2000-09-21 2002-03-28 Ono Pharmaceutical Co., Ltd. Agonistes du recepteur de l'ep4 comprenant comme principe actif des derives de la 8-azaprostaglandine
DE60130675T2 (de) * 2000-11-27 2008-01-24 Pfizer Products Inc., Groton Selektive agonisten des ep4 rezeptors für die behandlung von osteoporose
KR100826866B1 (ko) * 2001-07-23 2008-05-06 오노 야꾸힝 고교 가부시키가이샤 Ep4 아고니스트를 유효 성분으로 하는 골량 저하질환의 치료제
AU2003207900A1 (en) * 2002-03-18 2003-09-29 Pfizer Products Inc. Methods of treatment with selective ep4 receptor agonists
US6573294B1 (en) * 2002-05-14 2003-06-03 Allergan, Inc. 8-azaprostaglandin analogs as agents for lowering intraocular pressure
EP1586564B1 (de) * 2003-01-21 2012-11-28 Ono Pharmaceutical Co., Ltd. 8-azaprostaglandinderivate und deren medizinische verwendung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1386146A (en) * 1972-05-03 1975-03-05 Ici Ltd Cyclopentane derivatives
JPS511460A (en) * 1974-06-24 1976-01-08 Tanabe Seiyaku Co 22 piroridonjudotaino seiho
JPS514166A (ja) * 1974-06-28 1976-01-14 Tanabe Seiyaku Co 22piroridonjudotaino seiho
US3975399A (en) * 1974-08-06 1976-08-17 E. I. Du Pont De Nemours And Company 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones
DE2528664A1 (de) * 1975-06-27 1977-01-13 Hoechst Ag Pyrrolidone und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
PH17398A (en) 1984-08-08
JPS5555161A (en) 1980-04-22
BG31073A3 (en) 1981-10-15
ATA579477A (de) 1980-11-15
DK352077A (da) 1978-02-07
LU77936A1 (de) 1978-04-27
IL52615A (en) 1981-09-13
AR217080A1 (es) 1980-02-29
PT66891B (en) 1979-01-26
IE45505B1 (en) 1982-09-08
GR68688B (de) 1982-02-01
JPS5321159A (en) 1978-02-27
GB1556569A (en) 1979-11-28
CH624934A5 (de) 1981-08-31
SU818480A3 (ru) 1981-03-30
PT66891A (en) 1977-09-01
SU850000A3 (ru) 1981-07-23
AU2751577A (en) 1979-02-08
GB1556570A (en) 1979-11-28
FR2369260B1 (de) 1982-02-12
FI70009B (fi) 1986-01-31
FI772376A (de) 1978-02-07
DE2735904A1 (de) 1978-02-09
NL7708637A (nl) 1978-02-08
SE7708642L (sv) 1978-02-07
DD143768A5 (de) 1980-09-10
IL52615A0 (en) 1977-10-31
BE857506A (fr) 1978-02-06
FI70009C (fi) 1986-09-12
PL200124A1 (pl) 1978-05-22
PL112931B1 (en) 1980-11-29
AU508007B2 (en) 1980-03-06
YU192577A (en) 1983-04-30
DD136135A5 (de) 1979-06-20
FR2369260A1 (fr) 1978-05-26
ES471349A1 (es) 1979-09-16
NO772752L (no) 1978-02-07
JPS5531147B2 (de) 1980-08-15
SE423813B (sv) 1982-06-07
JPS585196B2 (ja) 1983-01-29
AT362887B (de) 1981-06-25
IE45505L (en) 1978-02-06
HU180273B (en) 1983-02-28
NZ184806A (en) 1980-04-28
CA1077948A (en) 1980-05-20
ES461388A1 (es) 1978-12-01
SU703016A3 (ru) 1979-12-05
ZA774704B (en) 1978-06-28

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