CS209458B2 - Method of making the complex of the insuline salt with the protamine - Google Patents
Method of making the complex of the insuline salt with the protamine Download PDFInfo
- Publication number
- CS209458B2 CS209458B2 CS722923A CS292372A CS209458B2 CS 209458 B2 CS209458 B2 CS 209458B2 CS 722923 A CS722923 A CS 722923A CS 292372 A CS292372 A CS 292372A CS 209458 B2 CS209458 B2 CS 209458B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- insulin
- protamine
- salt
- complex
- sodium
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13912071A | 1971-04-30 | 1971-04-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS209458B2 true CS209458B2 (en) | 1981-12-31 |
Family
ID=22485216
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS722923A CS209458B2 (en) | 1971-04-30 | 1972-04-28 | Method of making the complex of the insuline salt with the protamine |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US3758683A (de) |
| JP (1) | JPS5735185B1 (de) |
| BE (1) | BE782651A (de) |
| CA (1) | CA976085A (de) |
| CH (1) | CH566784A5 (de) |
| CS (1) | CS209458B2 (de) |
| DD (1) | DD100708A5 (de) |
| DE (1) | DE2219635C3 (de) |
| DK (1) | DK131760C (de) |
| ES (1) | ES402176A1 (de) |
| FI (1) | FI49773C (de) |
| FR (1) | FR2134658B1 (de) |
| GB (1) | GB1385086A (de) |
| HU (1) | HU166989B (de) |
| IL (1) | IL39181A (de) |
| NL (1) | NL178258C (de) |
| NO (1) | NO137178C (de) |
| PL (1) | PL86966B1 (de) |
| RO (1) | RO64387A (de) |
| SE (1) | SE378066B (de) |
| SU (1) | SU508162A3 (de) |
| YU (1) | YU36155B (de) |
| ZA (1) | ZA722243B (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK140801B (da) * | 1975-01-15 | 1979-11-19 | Nordisk Insulinlab | Fremgangsmåde til fremstilling af et stabilt langtidsvirkende insulinpræparat. |
| NL193099C (nl) * | 1981-10-30 | 1998-11-03 | Novo Industri As | Gestabiliseerde insuline-oplossing. |
| WO1988002633A1 (en) * | 1986-10-20 | 1988-04-21 | Novo Industri A/S | Protamine zinc insulin preparations |
| IE62879B1 (en) * | 1987-02-25 | 1995-03-08 | Novo Nordisk As | Novel insulin derivatives |
| DE19726167B4 (de) | 1997-06-20 | 2008-01-24 | Sanofi-Aventis Deutschland Gmbh | Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung |
| US6624141B1 (en) * | 1999-03-17 | 2003-09-23 | The Regents Of The University Of Michigan | Protamine fragment compositions and methods of use |
| DE10114178A1 (de) * | 2001-03-23 | 2002-10-10 | Aventis Pharma Gmbh | Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität |
| DE10227232A1 (de) * | 2002-06-18 | 2004-01-15 | Aventis Pharma Deutschland Gmbh | Saure Insulinzubereitungen mit verbesserter Stabilität |
| PT3228320T (pt) | 2008-10-17 | 2020-03-26 | Sanofi Aventis Deutschland | Combinação de uma insulina e de um agonista do glp-1 |
| TR201809460T4 (tr) | 2009-11-13 | 2018-07-23 | Sanofi Aventis Deutschland | Bir GLP- 1-agonisti, bir insülin ve metiyonin içeren farmasötik bileşim. |
| JP5973918B2 (ja) | 2009-11-13 | 2016-08-23 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Ｇｌｐ−１アゴニスト及びメチオニンを含む薬学的組成物 |
| JP6199186B2 (ja) | 2010-08-30 | 2017-09-20 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | ２型糖尿病の治療用の医薬の製造のためのａｖｅ００１０の使用 |
| US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
| AR087693A1 (es) | 2011-08-29 | 2014-04-09 | Sanofi Aventis Deutschland | Combinacion farmaceutica para uso en el control glucemico en pacientes con diabetes de tipo 2 |
| TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
| CA2970200A1 (en) | 2014-12-12 | 2016-06-16 | Sanofi-Aventis Deutschland Gmbh | Insulin glargine/lixisenatide fixed ratio formulation |
| TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第２型糖尿病病患治療 |
| TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第２型糖尿病病患之治療 |
| CN111050750A (zh) | 2017-08-24 | 2020-04-21 | 诺沃挪第克公司 | Glp-1组合物及其用途 |
| EP4106727A1 (de) | 2020-02-18 | 2022-12-28 | Novo Nordisk A/S | Pharmazeutische formulierungen |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR5038E (fr) * | 1904-03-09 | 1905-12-02 | Georges Frederic Brade | Perfectionnements dans la fabrication des organes du métronome |
| GB889769A (en) * | 1957-07-18 | 1962-02-21 | Nordisk Insulinlab | Slowly acting insulin preparation in crystalline form |
-
1971
- 1971-04-30 US US00139120A patent/US3758683A/en not_active Expired - Lifetime
-
1972
- 1972-04-04 ZA ZA722243A patent/ZA722243B/xx unknown
- 1972-04-10 IL IL39181A patent/IL39181A/en unknown
- 1972-04-17 FI FI721077A patent/FI49773C/fi active
- 1972-04-20 DD DD162448A patent/DD100708A5/xx unknown
- 1972-04-21 DE DE2219635A patent/DE2219635C3/de not_active Expired
- 1972-04-24 NO NO1423/72A patent/NO137178C/no unknown
- 1972-04-26 SU SU1778186A patent/SU508162A3/ru active
- 1972-04-26 BE BE782651A patent/BE782651A/xx not_active IP Right Cessation
- 1972-04-26 JP JP4209072A patent/JPS5735185B1/ja active Pending
- 1972-04-27 ES ES402176A patent/ES402176A1/es not_active Expired
- 1972-04-27 DK DK209472A patent/DK131760C/da not_active IP Right Cessation
- 1972-04-27 PL PL1972155003A patent/PL86966B1/pl unknown
- 1972-04-28 SE SE7205698A patent/SE378066B/xx unknown
- 1972-04-28 HU HUEI419A patent/HU166989B/hu unknown
- 1972-04-28 GB GB1974172A patent/GB1385086A/en not_active Expired
- 1972-04-28 CH CH633872A patent/CH566784A5/xx not_active IP Right Cessation
- 1972-04-28 YU YU1142/72A patent/YU36155B/xx unknown
- 1972-04-28 CS CS722923A patent/CS209458B2/cs unknown
- 1972-04-28 CA CA140,826A patent/CA976085A/en not_active Expired
- 1972-04-28 NL NLAANVRAGE7205865,A patent/NL178258C/xx not_active IP Right Cessation
- 1972-04-28 FR FR7215270A patent/FR2134658B1/fr not_active Expired
- 1972-04-29 RO RO7270743A patent/RO64387A/ro unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US3758683A (en) | 1973-09-11 |
| YU36155B (en) | 1982-02-25 |
| YU114272A (en) | 1981-06-30 |
| CA976085A (en) | 1975-10-14 |
| ES402176A1 (es) | 1975-03-01 |
| CH566784A5 (de) | 1975-09-30 |
| DE2219635C3 (de) | 1981-10-15 |
| DK131760C (da) | 1976-02-02 |
| IL39181A0 (en) | 1972-06-28 |
| NL178258B (nl) | 1985-09-16 |
| DE2219635B2 (de) | 1980-11-27 |
| DE2219635A1 (de) | 1972-11-09 |
| FI49773B (de) | 1975-06-30 |
| FR2134658B1 (de) | 1975-10-17 |
| NL178258C (nl) | 1986-02-17 |
| NO137178B (no) | 1977-10-10 |
| DD100708A5 (de) | 1973-10-05 |
| GB1385086A (en) | 1975-02-26 |
| IL39181A (en) | 1974-09-10 |
| BE782651A (fr) | 1972-10-26 |
| JPS5735185B1 (de) | 1982-07-27 |
| PL86966B1 (de) | 1976-06-30 |
| SU508162A3 (ru) | 1976-03-25 |
| FR2134658A1 (de) | 1972-12-08 |
| DK131760B (da) | 1975-09-01 |
| SE378066B (de) | 1975-08-18 |
| FI49773C (fi) | 1975-10-10 |
| ZA722243B (en) | 1973-11-28 |
| RO64387A (fr) | 1979-07-15 |
| HU166989B (de) | 1975-07-28 |
| NL7205865A (de) | 1972-11-01 |
| NO137178C (no) | 1978-01-18 |
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