CS208654B2 - Method of making the hydantoine - Google Patents

Method of making the hydantoine

Info

Publication number
CS208654B2
CS208654B2 CS793513A CS271980A CS208654B2 CS 208654 B2 CS208654 B2 CS 208654B2 CS 793513 A CS793513 A CS 793513A CS 271980 A CS271980 A CS 271980A CS 208654 B2 CS208654 B2 CS 208654B2
Authority
CS
Czechoslovakia
Prior art keywords
butyl
phenyl
formula
hydantoin
alkyl
Prior art date
Application number
CS793513A
Other languages
Czech (cs)
English (en)
Inventor
William B Jamieson
William J Ross
Robin G Simmonds
John P Verge
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of CS208654B2 publication Critical patent/CS208654B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/96—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CS793513A 1978-05-23 1979-05-21 Method of making the hydantoine CS208654B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB21352/78A GB1601310A (en) 1978-05-23 1978-05-23 Aryl hydantoins

Publications (1)

Publication Number Publication Date
CS208654B2 true CS208654B2 (en) 1981-09-15

Family

ID=10161451

Family Applications (2)

Application Number Title Priority Date Filing Date
CS793513A CS208653B2 (en) 1978-05-23 1979-05-21 Method of making the hydantoine
CS793513A CS208654B2 (en) 1978-05-23 1979-05-21 Method of making the hydantoine

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CS793513A CS208653B2 (en) 1978-05-23 1979-05-21 Method of making the hydantoine

Country Status (31)

Country Link
US (2) US4241073A (el)
EP (1) EP0005647B1 (el)
JP (1) JPS54160373A (el)
KR (1) KR830000635B1 (el)
AR (2) AR225143A1 (el)
AT (1) AT366034B (el)
AU (1) AU530968B2 (el)
BE (1) BE876435A (el)
BG (2) BG32115A4 (el)
CA (1) CA1120481A (el)
CH (2) CH639650A5 (el)
CS (2) CS208653B2 (el)
DD (1) DD143769A5 (el)
DE (1) DE2963061D1 (el)
DK (1) DK207579A (el)
ES (1) ES480850A1 (el)
FI (1) FI791614A (el)
FR (1) FR2426681A1 (el)
GB (1) GB1601310A (el)
GR (1) GR68363B (el)
HU (1) HU184648B (el)
IL (1) IL57343A (el)
LU (1) LU81300A1 (el)
MX (1) MX5604E (el)
NZ (1) NZ190512A (el)
PL (2) PL119612B1 (el)
PT (1) PT69648A (el)
RO (2) RO79703A (el)
SU (2) SU873878A3 (el)
YU (1) YU120179A (el)
ZA (1) ZA792501B (el)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3013647C2 (de) * 1980-04-09 1985-07-11 Degussa Ag, 6000 Frankfurt Verfahren zur Herstellung von 5-Arylidenhydantoinen (B)
US4431656A (en) * 1981-02-05 1984-02-14 Kanegafuchi Chemical Industry Company Limited 3,5-di-Tert-butylstyrene derivatives, salts thereof, and pharmaceutical compositions containing the same as an active ingredient
US4684735A (en) * 1985-07-01 1987-08-04 Stauffer Chemical Company Promotion of raney nickel hydrogenation catalyst
JPS6317864A (ja) * 1986-07-11 1988-01-25 Mitsui Toatsu Chem Inc ヒダントイン類の製造方法
NL8800099A (nl) * 1987-01-31 1988-08-16 Sandoz Ag Pilocarpinederivaten en werkwijzen voor het bereiden en toepassen van deze derivaten.
IE940525L (en) * 1988-05-25 1989-11-25 Warner Lambert Co Known and selected novel arylmethylenyl derivatives of¹thiazolidinones, imidazolidinones and oxazolidinones useful¹as antiallergy agents and antiinflammatory agents
US5143928A (en) * 1990-03-27 1992-09-01 Warner-Lambert Company 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents
WO1991017151A1 (en) * 1990-04-27 1991-11-14 Orion-Yhtymä Oy New pharmacologically active catechol derivatives
FR2687153B1 (fr) * 1992-02-07 1994-05-13 Hoechst Ste Francaise Procede de preparation de la (thenyl-2)-5 hydantouine.
AU2351795A (en) * 1994-04-28 1995-11-29 Yamanouchi Pharmaceutical Co., Ltd. Imidazolidinedione derivative
SE0100902D0 (sv) * 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
SE0100903D0 (sv) * 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
SE0103710D0 (sv) * 2001-11-07 2001-11-07 Astrazeneca Ab Compounds
MXPA04005123A (es) * 2001-11-30 2005-02-17 Lilly Co Eli Agonistas del receptor activado por proliferador de peroxisoma.
SE0202539D0 (sv) * 2002-08-27 2002-08-27 Astrazeneca Ab Compounds
GB0221246D0 (en) * 2002-09-13 2002-10-23 Astrazeneca Ab Compounds
FR2845000B1 (fr) * 2002-09-27 2005-05-27 Oreal Utilisation d'un compose heterocyclique ou de l'un de ses sels pour stimuler ou induire la pousse des cheveux et/ou freiner leur chute
US7648992B2 (en) 2004-07-05 2010-01-19 Astrazeneca Ab Hydantoin derivatives for the treatment of obstructive airway diseases
SE0401762D0 (sv) * 2004-07-05 2004-07-05 Astrazeneca Ab Novel compounds
SE0403085D0 (sv) * 2004-12-17 2004-12-17 Astrazeneca Ab Novel componds
SE0403086D0 (sv) * 2004-12-17 2004-12-17 Astrazeneca Ab Compounds
TW200831488A (en) * 2006-11-29 2008-08-01 Astrazeneca Ab Novel compounds
EA016386B1 (ru) * 2007-05-30 2012-04-30 Ф. Хоффманн-Ля Рош Аг Ненуклеозидные ингибиторы обратной транскриптазы
WO2009059243A1 (en) * 2007-11-01 2009-05-07 The Uab Research Foundation Treating and preventing viral infections
GB2463514C (en) * 2008-09-11 2018-09-26 Galapagos Nv Imidazolidine compounds and uses therefor
ITBO20090078A1 (it) * 2009-02-13 2010-08-14 Consiglio Nazionale Ricerche Composti per il trattamento del tumore alla prostata e procedimenti per la loro sintesi

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR910275A (fr) * 1944-11-14 1946-06-03 Nouvelles hydantoïnes et leur procédé de préparation
US2479065A (en) * 1945-09-06 1949-08-16 Du Pont Preparation of 5-benzylhydantoin
US2861079A (en) * 1956-06-04 1958-11-18 Dow Chemical Co Process for making unsaturated hydantoins
GB846601A (en) * 1958-01-13 1960-08-31 British Oxygen Res And Dev Ltd Vinyl hydantoins
US3365296A (en) * 1964-05-18 1968-01-23 Gen Aniline & Film Corp Light-sensitive ultraviolet absorbing compounds and diazotype materials containing the same
US3395153A (en) * 1964-12-16 1968-07-30 United States Borax Chem 3, 5-dialkylhydantoins
JPS5136332B1 (el) * 1970-12-09 1976-10-07
US3847933A (en) * 1970-12-09 1974-11-12 Exxon Research Engineering Co Acid catalyzed alkylation of hydantoin
US3932449A (en) * 1973-10-09 1976-01-13 Morton-Norwich Products, Inc. 5-(P-dimethylaminobenzyl) hydantoin
GB1575904A (en) * 1976-04-23 1980-10-01 Lilly Industries Ltd Phenyl piperazines
JPS54122276A (en) * 1978-03-15 1979-09-21 Kanegafuchi Chem Ind Co Ltd Preparation of 5-(2-thienyl) hydantion

Also Published As

Publication number Publication date
ATA373379A (de) 1981-07-15
PL222701A1 (el) 1980-12-15
FI791614A (fi) 1979-11-24
RO79703A (ro) 1982-08-17
IL57343A (en) 1982-09-30
KR830000635B1 (ko) 1983-03-23
SU988190A3 (ru) 1983-01-07
GB1601310A (en) 1981-10-28
US4293563A (en) 1981-10-06
PL215773A1 (el) 1980-07-14
DE2963061D1 (en) 1982-07-29
AT366034B (de) 1982-03-10
ZA792501B (en) 1980-05-28
MX5604E (es) 1983-11-07
PL125075B1 (en) 1983-03-31
FR2426681A1 (fr) 1979-12-21
AR224186A1 (es) 1981-10-30
LU81300A1 (fr) 1980-12-16
CA1120481A (en) 1982-03-23
PT69648A (en) 1979-06-01
HU184648B (en) 1984-09-28
NZ190512A (en) 1984-10-19
AU4728979A (en) 1979-11-29
EP0005647B1 (en) 1982-06-09
SU873878A3 (ru) 1981-10-15
US4241073A (en) 1980-12-23
AR225143A1 (es) 1982-02-26
PL119612B1 (en) 1982-01-30
RO76807A (ro) 1981-04-26
FR2426681B1 (el) 1983-08-12
CH643546A5 (fr) 1984-06-15
DK207579A (da) 1979-11-24
ES480850A1 (es) 1980-02-01
JPS54160373A (en) 1979-12-19
CH639650A5 (fr) 1983-11-30
IL57343A0 (en) 1979-09-30
CS208653B2 (en) 1981-09-15
DD143769A5 (de) 1980-09-10
BE876435A (fr) 1979-11-21
EP0005647A1 (en) 1979-11-28
BG32115A4 (en) 1982-05-14
YU120179A (en) 1983-02-28
AU530968B2 (en) 1983-08-04
BG31799A3 (en) 1982-03-15
GR68363B (el) 1981-12-23

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