CS208463B2 - Method of making the 4-/n-acetyl/amino-tetrahydro-1,3,5-triazine-2,6-dions - Google Patents

Method of making the 4-/n-acetyl/amino-tetrahydro-1,3,5-triazine-2,6-dions Download PDF

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Publication number
CS208463B2
CS208463B2 CS781045A CS104578A CS208463B2 CS 208463 B2 CS208463 B2 CS 208463B2 CS 781045 A CS781045 A CS 781045A CS 104578 A CS104578 A CS 104578A CS 208463 B2 CS208463 B2 CS 208463B2
Authority
CS
Czechoslovakia
Prior art keywords
group
formula
protons
isopropyl
alkyl
Prior art date
Application number
CS781045A
Other languages
Czech (cs)
English (en)
Inventor
Edward D Brown
Walter Hepworth
Ian T Kay
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Ltd filed Critical Ici Ltd
Publication of CS208463B2 publication Critical patent/CS208463B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/42—One nitrogen atom
    • C07D251/46—One nitrogen atom with oxygen or sulfur atoms attached to the two other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS781045A 1977-02-21 1978-02-17 Method of making the 4-/n-acetyl/amino-tetrahydro-1,3,5-triazine-2,6-dions CS208463B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7183/77A GB1599518A (en) 1977-02-21 1977-02-21 1,3,5-triazine-2,6-diones and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
CS208463B2 true CS208463B2 (en) 1981-09-15

Family

ID=9828208

Family Applications (2)

Application Number Title Priority Date Filing Date
CS781045A CS208463B2 (en) 1977-02-21 1978-02-17 Method of making the 4-/n-acetyl/amino-tetrahydro-1,3,5-triazine-2,6-dions
CS803610A CS208464B2 (en) 1977-02-21 1980-05-22 Method of making the 4-/n-acetyl/amino-tetrahydro-1,3,5-triazin-2,6-dions

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS803610A CS208464B2 (en) 1977-02-21 1980-05-22 Method of making the 4-/n-acetyl/amino-tetrahydro-1,3,5-triazin-2,6-dions

Country Status (32)

Country Link
US (1) US4156002A (no)
JP (1) JPS53105487A (no)
AR (1) AR220120A1 (no)
AT (1) AT358592B (no)
AU (1) AU519803B2 (no)
BE (1) BE864124A (no)
CA (1) CA1117867A (no)
CH (1) CH637646A5 (no)
CS (2) CS208463B2 (no)
DD (1) DD134091A5 (no)
DE (1) DE2807381A1 (no)
DK (1) DK67978A (no)
ES (3) ES467170A1 (no)
FI (1) FI64152C (no)
FR (1) FR2381034A1 (no)
GB (1) GB1599518A (no)
GR (1) GR62157B (no)
HU (2) HU182653B (no)
IE (1) IE46650B1 (no)
IL (1) IL54026A (no)
IT (1) IT1158652B (no)
LU (1) LU79092A1 (no)
MW (1) MW478A1 (no)
NL (1) NL7801921A (no)
NO (1) NO780576L (no)
NZ (1) NZ186406A (no)
PL (2) PL109995B1 (no)
PT (1) PT67668B (no)
SE (1) SE440775B (no)
SU (2) SU890976A3 (no)
ZA (1) ZA78671B (no)
ZM (1) ZM1878A1 (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0005911B1 (en) * 1978-05-26 1982-02-17 Imperial Chemical Industries Plc Analgesic 6-acylaminotetrahydro-1,3,5-triazine-2,4-dione derivatives, pharmaceutical compositions thereof, and process for their manufacture
GB8629567D0 (en) * 1986-12-10 1987-01-21 Boots Co Plc Therapeutic agents
US6348216B1 (en) * 1996-06-10 2002-02-19 Knoll Pharmaceutical Company Ibuprofen and narcotic analgesic compositions
US6361794B1 (en) 1996-06-12 2002-03-26 Basf Corporation Method of making ibuprofen and narcotic analgesic composition
CA2752269C (en) * 2009-02-13 2016-08-30 Hiroyuki Kai Novel triazine derivative and pharmaceutical composition comprising the same
JP6075621B2 (ja) 2010-08-10 2017-02-08 塩野義製薬株式会社 新規複素環誘導体およびそれらを含有する医薬組成物
WO2012020749A1 (ja) 2010-08-10 2012-02-16 塩野義製薬株式会社 トリアジン誘導体およびそれを含有する鎮痛作用を有する医薬組成物
WO2013118855A1 (ja) 2012-02-09 2013-08-15 塩野義製薬株式会社 複素環および炭素環誘導体
TWI637949B (zh) 2013-06-14 2018-10-11 塩野義製藥股份有限公司 胺基三衍生物及含有其等之醫藥組合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK117230B (da) * 1965-07-21 1970-03-31 Takeda Chemical Industries Ltd Analogifremgangsmåde til fremstilling af 1-phenyl- eller -cyclohexyl-5-(γ-carboxypropyl-, γ-hydroxy-n-butyl-, β-acetylethyl- eller γ-hydroxy-n-butyl)-barbitursyrer eller salte deraf.
GB1543037A (en) * 1975-02-05 1979-03-28 Ici Ltd Selective herbicidal triazine-diones
US4035365A (en) * 1973-11-01 1977-07-12 Imperial Chemical Industries Limited Triazinediones
JPS5623425B2 (no) * 1973-11-09 1981-05-30

Also Published As

Publication number Publication date
IE46650B1 (en) 1983-08-10
PT67668A (en) 1978-03-01
IL54026A (en) 1983-06-15
FI64152C (fi) 1983-10-10
FR2381034A1 (fr) 1978-09-15
CS208464B2 (en) 1981-09-15
PL107871B1 (pl) 1980-03-31
NO780576L (no) 1978-08-22
ES476427A1 (es) 1979-04-16
US4156002A (en) 1979-05-22
IT7820500A0 (it) 1978-02-21
PL109995B1 (en) 1980-06-30
GB1599518A (en) 1981-10-07
SE7801930L (sv) 1978-08-22
PL204641A1 (pl) 1978-12-04
DD134091A5 (de) 1979-02-07
ZA78671B (en) 1978-12-27
JPS53105487A (en) 1978-09-13
HU176980B (hu) 1981-06-28
NL7801921A (nl) 1978-08-23
ES467170A1 (es) 1979-08-16
AR220120A1 (es) 1980-10-15
MW478A1 (en) 1980-02-13
FI64152B (fi) 1983-06-30
ZM1878A1 (en) 1981-06-22
ATA127178A (de) 1980-02-15
CH637646A5 (de) 1983-08-15
GR62157B (en) 1979-03-01
NZ186406A (en) 1984-08-24
AT358592B (de) 1980-09-25
IT1158652B (it) 1987-02-25
LU79092A1 (fr) 1979-05-25
SU890976A3 (ru) 1981-12-15
FR2381034B1 (no) 1980-09-19
HU182653B (en) 1984-02-28
PT67668B (en) 1979-09-20
IE780217L (en) 1978-08-21
AU519803B2 (en) 1981-12-24
DE2807381A1 (de) 1978-08-24
ES476428A1 (es) 1979-05-01
FI780529A (fi) 1978-08-22
DK67978A (da) 1978-08-22
BE864124A (fr) 1978-08-21
AU3311278A (en) 1979-08-16
SU867303A3 (ru) 1981-09-23
CA1117867A (en) 1982-02-09
SE440775B (sv) 1985-08-19

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