CS207393B2 - Method of making the new oxothia compounds - Google Patents

Method of making the new oxothia compounds Download PDF

Info

Publication number
CS207393B2
CS207393B2 CS772337A CS61578A CS207393B2 CS 207393 B2 CS207393 B2 CS 207393B2 CS 772337 A CS772337 A CS 772337A CS 61578 A CS61578 A CS 61578A CS 207393 B2 CS207393 B2 CS 207393B2
Authority
CS
Czechoslovakia
Prior art keywords
group
alkyl
alkoxy
formula
oxo
Prior art date
Application number
CS772337A
Other languages
Czech (cs)
English (en)
Inventor
Raymond Bernasconi
Pier G Ferrini
Richard Goeschke
Jacques Gosteli
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH453876A external-priority patent/CH630082A5/de
Priority claimed from CH1599476A external-priority patent/CH629797A5/de
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of CS207393B2 publication Critical patent/CS207393B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/64—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CS772337A 1976-04-09 1977-04-07 Method of making the new oxothia compounds CS207393B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH453876A CH630082A5 (de) 1976-04-09 1976-04-09 Verfahren zur herstellung von oxothiaverbindungen.
CH1599476A CH629797A5 (en) 1976-12-20 1976-12-20 Process for the preparation of salts of oxothia compounds

Publications (1)

Publication Number Publication Date
CS207393B2 true CS207393B2 (en) 1981-07-31

Family

ID=25695718

Family Applications (4)

Application Number Title Priority Date Filing Date
CS772337A CS207394B2 (en) 1976-04-09 1977-04-07 Method of making the new oxothia compounds
CS772337A CS207393B2 (en) 1976-04-09 1977-04-07 Method of making the new oxothia compounds
CS772337A CS207395B2 (en) 1976-04-09 1977-04-07 Method of making the new oxothia compounds
CS772337A CS207392B2 (en) 1976-04-09 1977-04-07 Method of making the new oxothia compounds

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CS772337A CS207394B2 (en) 1976-04-09 1977-04-07 Method of making the new oxothia compounds

Family Applications After (2)

Application Number Title Priority Date Filing Date
CS772337A CS207395B2 (en) 1976-04-09 1977-04-07 Method of making the new oxothia compounds
CS772337A CS207392B2 (en) 1976-04-09 1977-04-07 Method of making the new oxothia compounds

Country Status (27)

Country Link
US (1) US4320138A (da)
JP (1) JPS52125158A (da)
AR (3) AR218869A1 (da)
AT (1) AT357148B (da)
CA (1) CA1112248A (da)
CS (4) CS207394B2 (da)
CY (1) CY1138A (da)
DD (1) DD130659A5 (da)
DE (1) DE2713584C2 (da)
DK (1) DK152046C (da)
ES (1) ES457528A1 (da)
FI (1) FI69461C (da)
FR (1) FR2347363A1 (da)
GB (1) GB1544339A (da)
GR (1) GR70652B (da)
HK (1) HK6182A (da)
HU (1) HU180438B (da)
IE (1) IE44987B1 (da)
IL (1) IL51847A (da)
KE (1) KE3185A (da)
MY (1) MY8200244A (da)
NL (1) NL7703802A (da)
NO (1) NO146810C (da)
NZ (1) NZ183747A (da)
PL (3) PL110653B1 (da)
SE (1) SE432930B (da)
SU (4) SU795475A3 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH634840A5 (de) * 1978-06-29 1983-02-28 Ciba Geigy Ag 2-oxo-2,3-dihydro-benzo(b)thiophen-verbindung und daraus hergestellte pharmazeutische praeparate.
AT392787B (de) * 1978-06-29 1991-06-10 Ciba Geigy Ag Verfahren zur herstellung des neuen n-(2-thienyl)-2-oxo-2,3-dihydro-benzo(b)thiophen-3-carboxamids

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3413308A (en) * 1966-09-02 1968-11-26 Dow Chemical Co Substituted benzo(b)thiophene-2-carboxanilides
US3655693A (en) * 1969-06-25 1972-04-11 Merck & Co Inc Anti-inflammatory salicyclic acid derivatives
US3676463A (en) * 1970-10-15 1972-07-11 Pfizer Oxobenzofuran carboxamides
US3971814A (en) * 1972-11-27 1976-07-27 Warner-Lambert Company Benzo(b)thiophene derivatives
GB1571847A (en) * 1974-01-02 1980-07-23 Systems Eng & Mfg Waste water treatment

Also Published As

Publication number Publication date
CS207395B2 (en) 1981-07-31
HU180438B (en) 1983-03-28
AT357148B (de) 1980-06-25
PL197311A1 (pl) 1978-01-16
MY8200244A (en) 1982-12-31
DD130659A5 (de) 1978-04-19
NZ183747A (en) 1979-01-11
FR2347363A1 (fr) 1977-11-04
NO771231L (no) 1977-10-11
NO146810B (no) 1982-09-06
SE7704033L (sv) 1977-10-10
DK152046C (da) 1988-07-18
JPS52125158A (en) 1977-10-20
FI771044A (da) 1977-10-10
CS207394B2 (en) 1981-07-31
HK6182A (en) 1982-02-19
JPS6218556B2 (da) 1987-04-23
ATA248577A (de) 1979-11-15
FI69461B (fi) 1985-10-31
SE432930B (sv) 1984-04-30
IL51847A0 (en) 1977-06-30
IL51847A (en) 1981-09-13
DE2713584A1 (de) 1977-10-20
SU791239A3 (ru) 1980-12-23
CS207392B2 (en) 1981-07-31
FR2347363B1 (da) 1979-03-09
KE3185A (en) 1982-04-02
SU898956A3 (ru) 1982-01-15
DK152046B (da) 1988-01-25
CY1138A (en) 1982-05-07
NO146810C (no) 1982-12-15
GB1544339A (en) 1979-04-19
NL7703802A (nl) 1977-10-11
AR224614A1 (es) 1981-12-30
ES457528A1 (es) 1978-08-16
IE44987L (en) 1977-10-09
PL110653B1 (en) 1980-07-31
PL111456B1 (en) 1980-08-30
SU795475A3 (ru) 1981-01-07
US4320138A (en) 1982-03-16
DK158777A (da) 1977-10-10
PL111459B1 (en) 1980-08-30
FI69461C (fi) 1986-02-10
DE2713584C2 (de) 1986-09-04
GR70652B (da) 1982-12-03
IE44987B1 (en) 1982-06-02
SU738510A3 (ru) 1980-05-30
CA1112248A (en) 1981-11-10
AR225401A1 (es) 1982-03-31
AR218869A1 (es) 1980-07-15

Similar Documents

Publication Publication Date Title
EP0182165A1 (en) Thienyl condensed-pyrazole derivatives
US4185109A (en) 1-Benzothiepin-4-carboxamides
CA2047103A1 (en) Antitumor compositions and methods of treatment
IE41457B1 (en) Thienothiazine derivatives
CA2394603A1 (en) Urotensin-ii receptor antagonists
PL100135B1 (pl) Sposob wytwarzania nowych pochodnych tieno/1,5/benzodwuazepiny
US4517184A (en) Benzodioxole derivatives
CS207393B2 (en) Method of making the new oxothia compounds
US3647800A (en) 10-substituted - 1 2 3 4 - tetrahydrobenzo(b)(1 6)naphthyridines useful as cns depressants
US3681360A (en) Antiviral substituted acridanones
AU2009202704B2 (en) New cycloalkylated benzothiadiazines, a process for their preparation and pharmaceutical compositions containing them
US3842082A (en) 4-piperazinyl-10h-thieno(3,2-c)(1)benzazepines
US3740394A (en) Thiazolo and thiazino pyrimidines
US4396621A (en) Certain 2-oxo-2,3-dihydro-3-benzothiophene-carboxamides and their pharmaceutical compositions
PT95743B (pt) /processo para a preparacao de derivados da-benzo{b//1,8/ naftiridina e de composicoes farmaceuticas que os contem
NZ206035A (en) Benzodioxole derivatives and pharmaceutical compositions
US4260779A (en) Oxothia compounds
US4166126A (en) 1-benzothiepin-4-carboxamides
PL89178B1 (da)
GB1561521A (en) 3,4 - dihydro - 3 - oxo - 4-carbamoyl - 2h - thieno (2,3 - e) - 1 - 2-thiazine 1,1 - dioxide derivatives
US4226998A (en) 1-Benzothiepin-4-carboxamides
CA1157018A (en) Benzodiazepinones, a process for their preparation, their use and medicaments containing them
US4242266A (en) 1-Benzothiepin-4-carboxylic acid derivatives
KR810001977B1 (ko) 트리아졸로-티에노-디아제핀-1-온의 제조방법
US4277484A (en) 1-Benzothiepin-4-carboxamides