CS200242B2 - Process for preparing inclusion complexes of derivatives prostacycline with beta-cyclodextrine - Google Patents

Process for preparing inclusion complexes of derivatives prostacycline with beta-cyclodextrine Download PDF

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Publication number
CS200242B2
CS200242B2 CS786036A CS603678A CS200242B2 CS 200242 B2 CS200242 B2 CS 200242B2 CS 786036 A CS786036 A CS 786036A CS 603678 A CS603678 A CS 603678A CS 200242 B2 CS200242 B2 CS 200242B2
Authority
CS
Czechoslovakia
Prior art keywords
prostacyclin
beta
cyclodextrin
solution
complexes
Prior art date
Application number
CS786036A
Other languages
Czech (cs)
English (en)
Inventor
Jozsef Szejtli
Magdolna Szejtli
Gyoergy Cseh
Istvan Stadler
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of CS200242B2 publication Critical patent/CS200242B2/cs

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CS786036A 1977-09-23 1978-09-18 Process for preparing inclusion complexes of derivatives prostacycline with beta-cyclodextrine CS200242B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77CI1770A HU179141B (ru) 1977-09-23 1977-09-23

Publications (1)

Publication Number Publication Date
CS200242B2 true CS200242B2 (en) 1980-08-29

Family

ID=10994670

Family Applications (1)

Application Number Title Priority Date Filing Date
CS786036A CS200242B2 (en) 1977-09-23 1978-09-18 Process for preparing inclusion complexes of derivatives prostacycline with beta-cyclodextrine

Country Status (20)

Country Link
JP (1) JPS5456685A (ru)
AT (1) AT369362B (ru)
BE (1) BE870646A (ru)
CH (1) CH637388A5 (ru)
CS (1) CS200242B2 (ru)
DD (1) DD138600A5 (ru)
DE (1) DE2840142A1 (ru)
DK (1) DK420778A (ru)
FI (1) FI65912C (ru)
FR (1) FR2404006A1 (ru)
GB (1) GB2006193B (ru)
GR (1) GR65001B (ru)
HU (1) HU179141B (ru)
IL (1) IL55569A (ru)
IT (1) IT1160661B (ru)
NL (1) NL7809643A (ru)
PL (1) PL121664B1 (ru)
SE (1) SE447574B (ru)
SU (1) SU847914A3 (ru)
YU (1) YU220678A (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53136513A (en) * 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds
US4352793A (en) * 1979-04-26 1982-10-05 Sumitomo Chemical Company, Limited Pharmaceutical composition comprising bencyclane fumarate and cyclodextrin
JPS5920230A (ja) * 1982-07-19 1984-02-01 チバ−ガイギ−・アクチエンゲゼルシヤフト ピルプロフエン含有薬剤
JPS61289034A (ja) * 1985-06-17 1986-12-19 Teijin Ltd イソカルバサイクリン類脂肪乳剤
DE3608088C2 (de) * 1986-03-07 1995-11-16 Schering Ag Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten
DE3740838A1 (de) * 1987-11-27 1989-06-08 Schering Ag Cyclodextrinclathrate von 5-cyano-prostacyclinderivaten und ihre verwendung als arzneimittel
WO2005073223A1 (ja) 2004-01-29 2005-08-11 Eisai R & D Management Co., Ltd. マクロライド系化合物の安定化方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS503362B1 (ru) * 1970-06-10 1975-02-04
US3953435A (en) * 1974-01-10 1976-04-27 Ono Pharmaceutical Company Aldehyde derivatives of prostaglandins
JPS5395958A (en) * 1977-01-31 1978-08-22 Ono Pharmaceut Co Ltd Prostaglandin analogues and process for their preparation
US4178367A (en) * 1977-02-21 1979-12-11 Ono Pharmaceutical Co. Ltd. Prostaglandin I2 analogues
JPS53136513A (en) * 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds

Also Published As

Publication number Publication date
GB2006193A (en) 1979-05-02
YU220678A (en) 1983-10-31
PL121664B1 (en) 1982-05-31
CH637388A5 (de) 1983-07-29
FI65912C (fi) 1984-08-10
BE870646A (fr) 1979-01-15
JPS5456685A (en) 1979-05-07
HU179141B (ru) 1982-08-28
IT7869160A0 (it) 1978-09-19
DD138600A5 (de) 1979-11-14
FI782878A (fi) 1979-03-24
SE447574B (sv) 1986-11-24
ATA677478A (de) 1982-05-15
AT369362B (de) 1982-12-27
SE7809946L (sv) 1979-03-24
DK420778A (da) 1979-03-24
NL7809643A (nl) 1979-03-27
SU847914A3 (ru) 1981-07-15
FR2404006A1 (fr) 1979-04-20
GR65001B (en) 1980-06-12
FI65912B (fi) 1984-04-30
IT1160661B (it) 1987-03-11
FR2404006B1 (ru) 1981-07-31
PL209773A1 (pl) 1979-06-04
IL55569A (en) 1981-12-31
DE2840142A1 (de) 1979-04-05
IL55569A0 (en) 1978-12-17
GB2006193B (en) 1982-05-26

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