CR10311A - Terapia combinatorial - Google Patents

Terapia combinatorial

Info

Publication number
CR10311A
CR10311A CR10311A CR10311A CR10311A CR 10311 A CR10311 A CR 10311A CR 10311 A CR10311 A CR 10311A CR 10311 A CR10311 A CR 10311A CR 10311 A CR10311 A CR 10311A
Authority
CR
Costa Rica
Prior art keywords
combinatory therapy
angiogenesis
antagonists
combinatory
therapy
Prior art date
Application number
CR10311A
Other languages
English (en)
Inventor
Anan Chuntharapai
Greg Plowman
Marc Tessier-Lavigne
Yan Wu
Weilan Ye
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CR10311A publication Critical patent/CR10311A/es

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    • C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
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    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Mycology (AREA)

Abstract

La presente invencion trata del uso de antagonistas VEGF y antagonistas alfa5beta1 para tratar el cancer e inhibir la angiogenesis y/o permeabilidad vascular, incluyendo la inhibicion de la angiogenesis anromal en enfermedades.
CR10311A 2006-03-21 2008-09-22 Terapia combinatorial CR10311A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78470406P 2006-03-21 2006-03-21
US78533006P 2006-03-22 2006-03-22
US87174306P 2006-12-22 2006-12-22

Publications (1)

Publication Number Publication Date
CR10311A true CR10311A (es) 2009-01-20

Family

ID=39402298

Family Applications (1)

Application Number Title Priority Date Filing Date
CR10311A CR10311A (es) 2006-03-21 2008-09-22 Terapia combinatorial

Country Status (27)

Country Link
US (3) US20090220504A1 (es)
EP (2) EP1989231B1 (es)
JP (2) JP5298007B2 (es)
KR (1) KR101454491B1 (es)
AR (1) AR060040A1 (es)
AU (1) AU2007319757B2 (es)
BR (1) BRPI0709338A2 (es)
CA (1) CA2646611A1 (es)
CR (1) CR10311A (es)
DK (1) DK1989231T3 (es)
EC (1) ECSP088835A (es)
ES (1) ES2544957T3 (es)
HR (1) HRP20150884T1 (es)
HU (1) HUE025989T2 (es)
IL (1) IL193926A (es)
MA (1) MA30384B1 (es)
MX (1) MX2008011905A (es)
MY (1) MY159375A (es)
NO (1) NO20084396L (es)
NZ (3) NZ571068A (es)
PL (1) PL1989231T3 (es)
PT (1) PT1989231E (es)
RS (1) RS54156B1 (es)
RU (1) RU2012129350A (es)
TW (1) TWI397535B (es)
UA (1) UA100969C2 (es)
WO (1) WO2008060645A2 (es)

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BRPI0711796A2 (pt) * 2006-05-24 2011-12-06 Bayer Schering Pharma Aktiendesellschaft anticorpos de bloqueio de função de integrinas anti-alfa5beta1 humanos e humanizados com imunogenicidade reduzida
JP2010534685A (ja) * 2007-07-27 2010-11-11 ファセット バイオテック コーポレイション チロシンキナーゼ阻害剤およびインテグリンα５β１（ＣＤ４９Ｅ）に対する抗体を含む薬学的な組み合わせ
AR066170A1 (es) * 2007-09-26 2009-07-29 Genentech Inc Anti integrina alfa 5 beta 1
CA2714071A1 (en) 2008-02-05 2009-08-13 Bristol-Myers Squibb Company Alpha 5 - beta 1 antibodies and their uses
CA2748158A1 (en) 2008-12-23 2010-07-01 Astrazeneca Ab Targeted binding agents directed to .alpha.5.beta.1 and uses thereof
JP6051048B2 (ja) 2009-03-25 2016-12-21 ジェネンテック， インコーポレイテッド 新規な抗α５β１抗体及びその使用
CN102253787B (zh) * 2010-05-21 2014-12-10 宸鸿科技(厦门)有限公司 电感式触控传感器及其触摸点侦测方法
US20140079637A1 (en) * 2011-03-23 2014-03-20 The Regents Of The University Of California Methods and compositions for improving antiangiogenic therapy with anti-integrins
US20150017091A1 (en) * 2011-08-18 2015-01-15 Cornell University Detection and treatment of metastatic disease
MX2019001355A (es) 2012-05-10 2023-01-17 Bioatla Llc Anticuerpos monoclonales multiespecíficos.
GB2509260B (en) * 2012-11-02 2016-05-04 True North Therapeutics Inc Anti-complement C1s antibodies and uses thereof
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
BR112018013407A2 (pt) 2015-12-30 2018-12-18 Kodiak Sciences Inc anticorpos e conjugados dos mesmos
WO2018106959A1 (en) 2016-12-07 2018-06-14 Progenity Inc. Gastrointestinal tract detection methods, devices and systems
EP4233902A3 (en) 2016-12-14 2024-02-28 Biora Therapeutics, Inc. Treatment of a disease of the gastrointestinal tract with an integrin inhibitor
WO2019147944A1 (en) 2018-01-26 2019-08-01 The Regents Of The University Of California Methods and compositions for treatment of angiogenic disordres using anti-vegf agents
US20230033021A1 (en) 2018-06-20 2023-02-02 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an integrin inhibitor
KR20210095165A (ko) 2018-11-19 2021-07-30 프로제너티, 인크. 바이오의약품으로 질환을 치료하기 위한 방법 및 디바이스
AU2020364071A1 (en) 2019-10-10 2022-05-26 Kodiak Sciences Inc. Methods of treating an eye disorder
WO2021108255A1 (en) 2019-11-25 2021-06-03 The Regents Of The University Of California Long-acting vegf inhibitors for intraocular neovascularization
EP4309722A2 (en) 2019-12-13 2024-01-24 Biora Therapeutics, Inc. Ingestible device for delivery of therapeutic agent to the gastrointestinal tract
CN117980334A (zh) * 2021-05-11 2024-05-03 帕西西娅治疗公司 α5β1整合素结合剂及其用途
US11723955B1 (en) 2022-05-13 2023-08-15 Allgenesis Biotherapeutics Inc. VEGFR fusion protein pharmaceutical composition

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EP1989231A2 (en) 2008-11-12
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