UA100969C2 - Антитіло, яке специфічно зв'язує людський альфа5бета1 (alpha5beta1) - Google Patents

Антитіло, яке специфічно зв'язує людський альфа5бета1 (alpha5beta1)

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Publication number
UA100969C2
UA100969C2 UAA200812103A UAA200812103A UA100969C2 UA 100969 C2 UA100969 C2 UA 100969C2 UA A200812103 A UAA200812103 A UA A200812103A UA A200812103 A UAA200812103 A UA A200812103A UA 100969 C2 UA100969 C2 UA 100969C2
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UA
Ukraine
Prior art keywords
antagonists
relates
present
therapy involving
combinatorial therapy
Prior art date
Application number
UAA200812103A
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English (en)
Russian (ru)
Inventor
Анан ЧУНТХАРАПАЙ
Грег ПЛАУМАН
Марк Тесс'є-Лавін
Янь У
Вейлань Е
Original Assignee
Дженентек, Інк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дженентек, Інк. filed Critical Дженентек, Інк.
Publication of UA100969C2 publication Critical patent/UA100969C2/uk

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Abstract

Винахід належить до антитіла, яке специфічно зв'язує людський альфа5бета1 (alpha5beta1), продукованого гібридомою, вибраної з групи, яка складається з гібридоми АТСС № РТА-7421 та гібридоми, депонованої як АТСС № РТА-7420. Винахід також належить до молекули нуклеїнової кислоти, що кодує антитіло, клітини-хазяїна, способу виявлення альфа5бета1 у зразку, композиції, що містить антитіло, способу інгібування ангіогенезу і/або судинної проникності у суб'єкта, способу лікування раку та набору для визначення альфа5бета1 у суб'єкта.
UAA200812103A 2006-03-21 2007-03-21 Антитіло, яке специфічно зв'язує людський альфа5бета1 (alpha5beta1) UA100969C2 (uk)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US78470406P 2006-03-21 2006-03-21
US78533006P 2006-03-22 2006-03-22
US87174306P 2006-12-22 2006-12-22
PCT/US2007/064572 WO2008060645A2 (en) 2006-03-21 2007-03-21 Combinatorial therapy involving alpha5beta1 antagonists

Publications (1)

Publication Number Publication Date
UA100969C2 true UA100969C2 (uk) 2013-02-25

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UAA200812103A UA100969C2 (uk) 2006-03-21 2007-03-21 Антитіло, яке специфічно зв'язує людський альфа5бета1 (alpha5beta1)

Country Status (27)

Country Link
US (3) US20090220504A1 (uk)
EP (2) EP1989231B1 (uk)
JP (2) JP5298007B2 (uk)
KR (1) KR101454491B1 (uk)
AR (1) AR060040A1 (uk)
AU (1) AU2007319757B2 (uk)
BR (1) BRPI0709338A2 (uk)
CA (1) CA2646611A1 (uk)
CR (1) CR10311A (uk)
DK (1) DK1989231T3 (uk)
EC (1) ECSP088835A (uk)
ES (1) ES2544957T3 (uk)
HR (1) HRP20150884T1 (uk)
HU (1) HUE025989T2 (uk)
IL (1) IL193926A (uk)
MA (1) MA30384B1 (uk)
MX (1) MX2008011905A (uk)
MY (1) MY159375A (uk)
NO (1) NO20084396L (uk)
NZ (3) NZ571068A (uk)
PL (1) PL1989231T3 (uk)
PT (1) PT1989231E (uk)
RS (1) RS54156B1 (uk)
RU (1) RU2012129350A (uk)
TW (1) TWI397535B (uk)
UA (1) UA100969C2 (uk)
WO (1) WO2008060645A2 (uk)

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BRPI0711796A2 (pt) * 2006-05-24 2011-12-06 Bayer Schering Pharma Aktiendesellschaft anticorpos de bloqueio de função de integrinas anti-alfa5beta1 humanos e humanizados com imunogenicidade reduzida
JP2010534685A (ja) * 2007-07-27 2010-11-11 ファセット バイオテック コーポレイション チロシンキナーゼ阻害剤およびインテグリンα５β１（ＣＤ４９Ｅ）に対する抗体を含む薬学的な組み合わせ
AR066170A1 (es) * 2007-09-26 2009-07-29 Genentech Inc Anti integrina alfa 5 beta 1
CA2714071A1 (en) 2008-02-05 2009-08-13 Bristol-Myers Squibb Company Alpha 5 - beta 1 antibodies and their uses
CA2748158A1 (en) 2008-12-23 2010-07-01 Astrazeneca Ab Targeted binding agents directed to .alpha.5.beta.1 and uses thereof
JP6051048B2 (ja) 2009-03-25 2016-12-21 ジェネンテック， インコーポレイテッド 新規な抗α５β１抗体及びその使用
CN102253787B (zh) * 2010-05-21 2014-12-10 宸鸿科技(厦门)有限公司 电感式触控传感器及其触摸点侦测方法
US20140079637A1 (en) * 2011-03-23 2014-03-20 The Regents Of The University Of California Methods and compositions for improving antiangiogenic therapy with anti-integrins
US20150017091A1 (en) * 2011-08-18 2015-01-15 Cornell University Detection and treatment of metastatic disease
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