CO6511258A2 - Proceso fotoquimico para preparar artemisinina - Google Patents
Proceso fotoquimico para preparar artemisininaInfo
- Publication number
- CO6511258A2 CO6511258A2 CO12048458A CO12048458A CO6511258A2 CO 6511258 A2 CO6511258 A2 CO 6511258A2 CO 12048458 A CO12048458 A CO 12048458A CO 12048458 A CO12048458 A CO 12048458A CO 6511258 A2 CO6511258 A2 CO 6511258A2
- Authority
- CO
- Colombia
- Prior art keywords
- artemisinine
- prepare
- photochemical process
- artemisinin
- preparing
- Prior art date
Links
- BLUAFEHZUWYNDE-NNWCWBAJSA-N artemisinin Chemical compound C([C@](OO1)(C)O2)C[C@H]3[C@H](C)CC[C@@H]4[C@@]31[C@@H]2OC(=O)[C@@H]4C BLUAFEHZUWYNDE-NNWCWBAJSA-N 0.000 title abstract 4
- 229960004191 artemisinin Drugs 0.000 title abstract 4
- JYGAZEJXUVDYHI-DGTMBMJNSA-N dihydroartemisinic acid Chemical compound C1CC(C)=C[C@@H]2[C@H]([C@@H](C)C(O)=O)CC[C@@H](C)[C@@H]21 JYGAZEJXUVDYHI-DGTMBMJNSA-N 0.000 abstract 4
- 229930101531 artemisinin Natural products 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- JYGAZEJXUVDYHI-UHFFFAOYSA-N dihydroartemisininic acid Natural products C1CC(C)=CC2C(C(C)C(O)=O)CCC(C)C21 JYGAZEJXUVDYHI-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000007539 photo-oxidation reaction Methods 0.000 abstract 1
- 239000003504 photosensitizing agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/96—Esters of carbonic or haloformic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/36—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/08—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
- B01J19/12—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor employing electromagnetic waves
- B01J19/122—Incoherent waves
- B01J19/127—Sunlight; Visible light
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C68/00—Preparation of esters of carbonic or haloformic acids
- C07C68/02—Preparation of esters of carbonic or haloformic acids from phosgene or haloformates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
- C07D493/18—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/26—All rings being cycloaliphatic the ring system containing ten carbon atoms
- C07C2602/28—Hydrogenated naphthalenes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Electromagnetism (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Laminated Bodies (AREA)
Abstract
La presente invención se refiere a un proceso foto químico para preparar artemisinina y determinados compuestos derivados de ácido dihidroartemisínico útiles para preparar artemisinina, que comprende las etapas de preparar una mezcla que comprende un compuesto derivado de ácido dihidroartemisínico, por lo menos un solvente orgánico y un fotosensibilizador; someter dicha mezcla a fotooxidación por medio de una fuente de luz y recuperar la artemisinina así obtenida.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09305805A EP2289897A1 (en) | 2009-09-01 | 2009-09-01 | Photochemical process for producing artemisinin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO6511258A2 true CO6511258A2 (es) | 2012-08-31 |
Family
ID=41557558
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO12048458A CO6511258A2 (es) | 2009-09-01 | 2012-03-22 | Proceso fotoquimico para preparar artemisinina |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US8507697B2 (es) |
| EP (2) | EP2289897A1 (es) |
| JP (1) | JP5719366B2 (es) |
| KR (1) | KR101787777B1 (es) |
| CN (1) | CN102596967B (es) |
| AP (1) | AP2988A (es) |
| AU (2) | AU2010291253B2 (es) |
| BR (1) | BR112012004702B1 (es) |
| CA (1) | CA2772264C (es) |
| CL (1) | CL2012000554A1 (es) |
| CO (1) | CO6511258A2 (es) |
| CY (1) | CY1121969T1 (es) |
| EA (1) | EA021181B1 (es) |
| ES (1) | ES2561080T3 (es) |
| HK (1) | HK1171740A1 (es) |
| HU (1) | HUE027477T2 (es) |
| IL (1) | IL218346A0 (es) |
| MA (1) | MA33596B1 (es) |
| MX (1) | MX358030B (es) |
| MY (1) | MY155962A (es) |
| NZ (1) | NZ598878A (es) |
| PL (1) | PL2473512T3 (es) |
| SG (1) | SG178600A1 (es) |
| SI (1) | SI2473512T1 (es) |
| WO (1) | WO2011026865A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2289897A1 (en) * | 2009-09-01 | 2011-03-02 | Sanofi-Aventis | Photochemical process for producing artemisinin |
| EP2751113B1 (en) * | 2011-08-29 | 2017-07-05 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Method and device for the synthesis of artemisinin |
| CN103788110B (zh) * | 2013-11-28 | 2015-10-28 | 湖南科源生物制品有限公司 | 一种以青蒿酸为原料制备青蒿素的方法 |
| CN110327984B (zh) * | 2019-07-12 | 2022-04-22 | 西北工业大学 | 一种用于双氢青蒿酸制备青蒿素的Pt@PCN-224光催化剂及其制备方法 |
| CN110590802B (zh) * | 2019-09-18 | 2021-02-02 | 浙江海正药业股份有限公司 | 一种青蒿素的化学半合成方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5002582A (en) * | 1982-09-29 | 1991-03-26 | Bio-Metric Systems, Inc. | Preparation of polymeric surfaces via covalently attaching polymers |
| CN1023603C (zh) * | 1990-01-12 | 1994-01-26 | 中国科学院上海有机化学研究所 | 青蒿酸合成青蒿素的方法 |
| US4992561A (en) * | 1990-05-11 | 1991-02-12 | The United States Of America As Represented By The Secretary Of The Army | Simple conversion of artemisinic acid into artemisinin |
| CN1034017C (zh) * | 1993-03-25 | 1997-02-12 | 中国科学院上海有机化学研究所 | 4位取代青蒿素类似物 |
| IN184682B (es) | 1995-12-29 | 2000-09-23 | Council Scient Ind Res | |
| JP3148136B2 (ja) * | 1996-12-26 | 2001-03-19 | 高砂香料工業株式会社 | 新規なキラルジホスフィン化合物、その製造中間体、該ジホス フィン化合物を配位子とする遷移金属錯体並びに該錯体を含む 不斉水素化触媒 |
| US5995084A (en) * | 1997-01-17 | 1999-11-30 | Tritech Microelectronics, Ltd. | Touchpad pen-input and mouse controller |
| IN188174B (es) | 1997-03-17 | 2002-08-31 | Council Scient Ind Res | |
| JP3549390B2 (ja) * | 1998-03-23 | 2004-08-04 | 高砂香料工業株式会社 | ルテニウム−ホスフィン錯体及びその製造方法 |
| US20060270863A1 (en) | 2005-05-27 | 2006-11-30 | Amyris Biotechnologies | Conversion of amorpha-4,11-diene to artemisinin and artemisinin precursors |
| WO2009088404A1 (en) | 2007-12-30 | 2009-07-16 | Amyris Biotechnologies, Inc. | Processes for the preparation of artemisinin an its precursors |
| EP2289897A1 (en) * | 2009-09-01 | 2011-03-02 | Sanofi-Aventis | Photochemical process for producing artemisinin |
-
2009
- 2009-09-01 EP EP09305805A patent/EP2289897A1/en not_active Withdrawn
-
2010
- 2010-09-01 AU AU2010291253A patent/AU2010291253B2/en active Active
- 2010-09-01 PL PL10751915T patent/PL2473512T3/pl unknown
- 2010-09-01 MY MYPI2012000913A patent/MY155962A/en unknown
- 2010-09-01 US US12/873,925 patent/US8507697B2/en active Active
- 2010-09-01 WO PCT/EP2010/062811 patent/WO2011026865A1/en active Application Filing
- 2010-09-01 EA EA201270343A patent/EA021181B1/ru not_active IP Right Cessation
- 2010-09-01 EP EP10751915.9A patent/EP2473512B1/en active Active
- 2010-09-01 CN CN201080049390.1A patent/CN102596967B/zh active Active
- 2010-09-01 BR BR112012004702-7A patent/BR112012004702B1/pt active IP Right Grant
- 2010-09-01 JP JP2012526082A patent/JP5719366B2/ja active Active
- 2010-09-01 HU HUE10751915A patent/HUE027477T2/en unknown
- 2010-09-01 KR KR1020127008220A patent/KR101787777B1/ko active IP Right Grant
- 2010-09-01 MX MX2012002652A patent/MX358030B/es active IP Right Grant
- 2010-09-01 CA CA2772264A patent/CA2772264C/en active Active
- 2010-09-01 SG SG2012014114A patent/SG178600A1/en unknown
- 2010-09-01 NZ NZ598878A patent/NZ598878A/xx unknown
- 2010-09-01 SI SI201031120A patent/SI2473512T1/sl unknown
- 2010-09-01 ES ES10751915.9T patent/ES2561080T3/es active Active
- 2010-09-01 AP AP2012006186A patent/AP2988A/xx active
-
2012
- 2012-02-27 IL IL218346A patent/IL218346A0/en active IP Right Grant
- 2012-02-29 CL CL2012000554A patent/CL2012000554A1/es unknown
- 2012-03-21 MA MA34707A patent/MA33596B1/fr unknown
- 2012-03-22 CO CO12048458A patent/CO6511258A2/es active IP Right Grant
- 2012-12-03 HK HK12112455.9A patent/HK1171740A1/zh unknown
-
2013
- 2013-07-12 US US13/940,316 patent/US20130299338A1/en not_active Abandoned
-
2016
- 2016-01-27 CY CY20161100071T patent/CY1121969T1/el unknown
- 2016-06-16 AU AU2016204057A patent/AU2016204057B2/en active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Application granted |